91 research outputs found
La Cooperación comercial CE-ACP : Evaluación del Protocolo del Azúcar
A pesar de que estos compromisos comerciales especiales han implicado sustanciales transferencias para algunos países ACP participantes, éstas no han logrado, en general, la expansión del bienestar económico de dichos países. Dan soporte a ello determinados elementos influyentes tanto en el diseño como en la aplicación del Protocolo. En consecuencia, se pretende aportar líneas de mejora de la política europea de cooperación al desarrollo de los países ACP beneficiarios del Protocolo en el ámbito del azúcar, en el marco de la nueva cooperación comercial CE-ACP y la propuesta de reforma de la OCM del azúcar.Tot i que aquests compromisos comercials especials han implicat substancials transferències per alguns països ACP participants, aquestes no han aconseguit, en general, l'expansió del benestar econòmic d'aquests països. Donen suport a això determinats elements influents tant en el disseny com en l'aplicació del Protocol. En conseqüència, es pretén aportar línies de millora de la política europea de cooperació al desenvolupament dels països ACP beneficiaris del Protocol en l'àmbit del sucre, en el marc de la nova cooperació comercial CE-ACP i la proposta de reforma de l'OCM del sucre
Las relaciones comerciales de la Union Europea con sus vecinos: europeizacion, internacionalizacion o coordinacion?
La politica de Vecindad de la Union Europea se acostumbra a interpretar como un instrumento de europeizacion forzada. Gracias a su fuerza de negociacion, la Union Europea impondria a sus vecinos su modelo economico y hasta politico y social. Esta sin embargo no es la evidencia que se obtiene en el ambito del comercio. En consonancia con el modelo teorico de relaciones exteriores desarrollado por varios investigadores bajo la direccion de Esther Barbe, observamos como, en el ambito comercial, el modelo de relaciones entre la Union Europea y cuatro paises de la politica de Vecindad puede ser tanto de europeizacion como tambien de internacionalizacion o de coordinacion. El tipo de modelo aplicado viene condicionado, como asevera el marco teorico, por el cumplimiento de las condiciones necesarias que se requieren para que Europa imponga sus normas: legitimidad, incentivos y coherencia interna. Estas condiciones varian en funcion tanto del tema tratado como del pais vecino.trade policy, european neighbourhood policy, european union, europeanisation
20 anys de Catalunya a la Unió Europea
Aquest llibre aprofita la efemèride del vintè aniversari de la integració de Catalunya a la UE per analitzar l'impacte de les principals polítiques europees i la seva influència en l'evolució de les polítiques a nivell catalàEste libro aprovecha la efeméride del vigésimo aniversario de la integración de Cataluña en la UE para analizar el impacto de las principales políticas europeas y su influencia en la evolución de las políticas a nivel catalá
Safety and efficacy of a feed additive consisting of endo‐1,4‐beta‐xylanase (produced by Aspergillus oryzae DSM 33700) (RONOZYME® WX (CT/L)) for all poultry species and all Suidae (DSM nutritional products ltd)
Free PMC article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585426/The additive RONOZYME® WX (CT/L) contains endo-1,4-beta-xylanase produced with a genetically modified strain of the filamentous fungus Aspergillus oryzae; the additive is currently authorised for poultry for fattening, weaned piglets, pigs for fattening, lactating sows and laying hens. The applicant has requested to change the production strain, substituting strain A. oryzae DSM 26372 with A. oryzae DSM 33700, and to extend the use of the additive to all poultry species and all Suidae. RONOZYME® WX (CT/L), manufactured with the production strain A. oryzae DSM 33700, did not give rise to safety concerns with regard to the genetic modification of the production strain. No viable cells of the production strain nor its DNA were detected in an intermediate product representative of both final formulations of the additive. RONOZYME® WX (CT/L) was considered safe for all poultry species and all Suidae at the recommended inclusion levels. The use of RONOZYME® WX CT and L manufactured with the production strain A. oryzae DSM 33700 raised no concerns for consumers. RONOZYME® WX L is not an eye irritant; however, no conclusions could be drawn on the potential of RONOZYME® WX CT to be an eye irritant. Both formulations are not irritant to the skin, but due to the lack of data, the FEEDAP Panel was not able to conclude on the potential of both formulations of the additive to be skin sensitisers. Due to the proteinaceous nature of the active substance, the additive is considered a respiratory sensitiser. The additive manufactured by A. oryzae DSM 33700 raises no safety concerns for the environment. The additive has the potential to be efficacious in all poultry species and all Suidae at 100 and 200 FXU/kg complete feed, respectively.info:eu-repo/semantics/publishedVersio
Safety and efficacy of the feed additive consisting of protease produced by Bacillus licheniformis DSM 33099 (ProAct 360) for use in poultry species for fattening or reared for laying/breeding (DSM Nutritional Products Ltd)
Free PMC article:Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a protease (ProAct 360) produced by a genetically modified strain of Bacillus licheniformis (DSM 33099) as a zootechnical feed additive for poultry species for fattening or reared for laying/breeding. The production strain and its recombinant DNA were not detected in an intermediate concentrated product representative of the final formulation. The final product did not trigger a safety concern with regard to the genetic modification. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that ProAct 360 is considered safe for all growing poultry species at the recommended inclusion level of 30,000 NFP/kg complete feed. The use ProAct 360 as a feed additive did not give rise to concerns for the consumers or the environment. The additive is not an eye or a dermal irritant but should be considered a respiratory sensitiser. In the absence of data, no conclusions could be reached on the skin sensitisation potential of the additive. The FEEDAP Panel concluded that the additive has the potential to be efficacious at 30,000 NFP/kg complete feed for all poultry species for fattening or reared for laying/breeding.info:eu-repo/semantics/publishedVersio
Autoantibodies against type I IFNs in patients with critical influenza pneumonia
In an international cohort of 279 patients with hypoxemic influenza pneumonia, we identified 13 patients (4.6%) with autoantibodies neutralizing IFN-alpha and/or -omega, which were previously reported to underlie 15% cases of life-threatening COVID-19 pneumonia and one third of severe adverse reactions to live-attenuated yellow fever vaccine. Autoantibodies neutralizing type I interferons (IFNs) can underlie critical COVID-19 pneumonia and yellow fever vaccine disease. We report here on 13 patients harboring autoantibodies neutralizing IFN-alpha 2 alone (five patients) or with IFN-omega (eight patients) from a cohort of 279 patients (4.7%) aged 6-73 yr with critical influenza pneumonia. Nine and four patients had antibodies neutralizing high and low concentrations, respectively, of IFN-alpha 2, and six and two patients had antibodies neutralizing high and low concentrations, respectively, of IFN-omega. The patients' autoantibodies increased influenza A virus replication in both A549 cells and reconstituted human airway epithelia. The prevalence of these antibodies was significantly higher than that in the general population for patients 70 yr of age (3.1 vs. 4.4%, P = 0.68). The risk of critical influenza was highest in patients with antibodies neutralizing high concentrations of both IFN-alpha 2 and IFN-omega (OR = 11.7, P = 1.3 x 10(-5)), especially those <70 yr old (OR = 139.9, P = 3.1 x 10(-10)). We also identified 10 patients in additional influenza patient cohorts. Autoantibodies neutralizing type I IFNs account for similar to 5% of cases of life-threatening influenza pneumonia in patients <70 yr old
COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study
Background:
The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms.
Methods:
International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms.
Results:
‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≤ 18 years: 69, 48, 23; 85%), older adults (≥ 70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P < 0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country.
Interpretation:
This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men
Underlying Event measurements in pp collisions at and 7 TeV with the ALICE experiment at the LHC
Evaluación de impacto del Protocolo del Azúcar CE-ACP
[spa] Con el ánimo de contribuir a la construcción de la nueva cooperación comercial entre la Comunidad Europea (CE) y los países de África, el Caribe y el Pacífico (ACP), esta tesis se centra en el estudio del actual régimen de acceso a productos agrícolas concedido por la CE al grupo ACP. En concreto, se realiza un análisis y una evaluación del Protocolo del Azúcar CE-ACP (o, formalmente, el Protocolo nº 3 sobre el azúcar ACP), el cual aparece, por primera vez, en el Convenio de Lomé firmado el 28 de febrero de 1975. La principal preocupación por este instrumento de cooperación en particular es que su contenido es más beneficioso que el los demás Protocolos de productos agrícolas. Así, este acuerdo comercial sobre el azúcar es el único que se basa en un compromiso de compra, por parte de la CE, y de venta, por el lado de los ACP, de unas cantidades especificadas en el marco de un elevado precio garantizado. En la práctica, estos compromisos especiales han implicado transferencias monetarias sustanciales y un nivel de estabilidad significativo de los ingresos de exportación de azúcar para algunos de los países ACP participantes, especialmente para aquellos que presentaron vínculos comerciales históricos con Gran Bretaña. El objetivo final de este estudio consiste en proponer si el Protocolo del Azúcar CE-ACP debe ser integrado en los AAE o, por lo contrario, si es mejor mantenerlo bajo la posible exclusión permitida en el artículo XXIV del Acuerdo General sobre Aranceles y Comercio (GATT). Esta investigación también presenta la opción para el Protocolo del Azúcar de ser incluido en el Sistema de Preferencias Generalizadas (SPG) de la CE, aunque las reducciones arancelarias y no arancelarias, junto a las exenciones específicas, sean menos generosas que las otorgadas a las importaciones europeas de productos ACP. Con esta finalidad, en este estudio se efectúa una evaluación de impacto del Protocolo del Azúcar CE-ACP sobre el desarrollo económico de los países ACP beneficiarios. Con ello, se demuestra que las transferencias monetarias implícitas apropiadas por las empresas azucareras de los Estados ACP participantes no han logrado, en general, una expansión del bienestar económico de sus economías. Este resultado ha sido alcanzado utilizando distintos modelos econométricos: un modelo de regresión lineal, un modelo de corrección de errores y un modelo con datos panel. En consecuencia, concluimos que el Protocolo del Azúcar CE-ACP no ha funcionado como un verdadero instrumento de cooperación al desarrollo. Para recomendar cómo mejorar las relaciones comerciales CE-ACP sobre el azúcar, el trabajo econométrico realizado se ha complementado con el análisis del funcionamiento del mercado internacional del azúcar (especialmente en relación a los precios y a los flujos comerciales). Asimismo, se ha considerado la reforma de la Política Agrícola Común ante los cambios que implicará en el mercado europeo del azúcar. Todos estos elementos nos permiten sugerir dos opciones alternativas al Protocolo, permitidas en el Acuerdo de Cotonú, con vistas a dirigir la cooperación comercial CE-ACP sobre el azúcar desde 2008, momento en el que está prevista la progresiva aplicación de los Acuerdos de Asociación Económica (AAE) CE-ACP.Ambas opciones son compatibles con las normas de la Organización Mundial del Comercio y dependen de la decisión de cada Estado ACP respecto a la celebración de un AAE con la CE. Por un lado, para aquellos Estados ACP que decidan implementar un AAE, consideramos que el azúcar debería quedar cubierto en los esquemas resultantes de integración económica entre ambas Partes, lo que significa que se debería eliminar cualquier restricción que dificulte el comercio CE-ACP de azúcar. Por otro lado, en el caso de que algunos países ACP no alcancen un AAE con la Comunidad Europea, creemos que el azúcar tendría que formar parte del SPG mejorado de la CE, que será el trato comercial más probable que la CE ofrecerá a estos países ACP, como a los demás países en desarrollo. En cualquier caso, el proceso de cambio debería acompañarse de la concesión de ayuda financiera y técnica dirigida a dichos países ACP para ayudarlos a reestructurar el sector del azúcar y, en general, apoyarlos a que se adapten a las nuevas condiciones económicas de un mercado más globalizado. NOTA: Esta tesis recibió el "Premi Maspons i Anglasell" del "Patronat Català Pro Europa" (actualmente "Patronat Catalunya-Món") de la Generalitat de Catalunya a la mejor tesis doctoral en el bienio 2004-2005 (14a edición), el día 18 de abril de 2007.[eng] IMPACT EVALUATION OF THE ACP-EC SUGAR PROTOCOL.In order to contribute in constructing the new trade co-operation between the European Community (EC) and the African, Caribbean and Pacific States (ACP), this thesis focuses in the current European access regime for agricultural products originating from the ACP Group. To be exact, it is carried out an analysis and evaluation of the ACP-EC Sugar Protocol (or, formally, Protocol 3 on ACP sugar) appearing the first time, in the ACP-EC Convention of Lomé signed on 28th February 1975. The principal reason for this particular co-operation instrument is that its provision is more beneficial than the other agricultural products Protocols. Thus, this commercial sugar agreement is the only one based on a purchase commitment from the EC and a sale commitment from the ACP beneficiary countries, of specified quantities, in the framework of a guaranteed high price -similar to the intervention price in the European sugar market-. In practice, this special trading agreement has implied substantial income transfers and a significant stability level of sugar export earnings for some of the ACP participant countries, especially those that presented historic sugar trading links with the United Kingdom. The final goal of this study consists of proposing if the ACP-EC Sugar Protocol has to be integrated in the EPAs or, on the contrary, it is better to keep it under the possible exclusion permitted in article XXIV of the General Agreement on Tariffs and Trade (GATT). This research also presents the option for the Sugar Protocol to be included in the EC's Generalised System of Preferences (GSP), even though tariff and non-tariff reductions, together with the specific exemptions, are less generous than those granted to European imports of ACP products. Within this aim, this study deals with an impact evaluation of the ACP-EC Sugar Protocol over economic development of ACP beneficiary countries. It demonstrates that the implicit income transfers by sugar companies from the ACP Sugar Group has not implied, in general, an economic welfare expansion for their economies. This outcome has been obtained using different econometric models: a linear regression model, an error correction model and a model with panel data. In consequence, we conclude that the ACP-EC Sugar Protocol has not functioned as a true development co-operation instrument.In order to recommend how to improve the ACP-EC trade relations on sugar, that econometric study has been complemented with an analysis of the international sugar market functioning (especially, referring to prices and commercial flows). The changes the Common Agriculture Policy reform will imply on the European sugar market have been considered as well. All of these items allow us to suggest the two alternative options to the Protocol, permitted in the Cotonou Agreement, in order to lead the ACP-EC trade co-operation on sugar since 2008. Both options are compatible with the World Trade Organisation rules and depend on the ACP State decision about the celebration of an EPA with the EC. On the one hand, for those ACP States that decide to implement an EPA, we consider that sugar should be covered in the resulting economic integration schemes between both parties, which means that any restriction on ACP-EC sugar trade should be eliminated. On the other hand, in the case that some ACP countries do not achieve an EPA with the EC, we believe that sugar should take part of the improved EC's GSP, which will be the most probable trade treatment that the EC will offer to those ACP States, as well as to the rest of developing countries. In both cases, the change process should be accompanied with the granting of financial and technical assistance to these ACP countries in order to help them to restructure the sugar sector and, in general, to support them to adjust to the new economic conditions within more globalised market. N.B.: Maspons i Anglasell Prize awarded by the Patronat Català Pro Europa (presently, Patronat Catalunya-Món) of la Generalitat (government institution) of Catalonia (Spain) for the best doctoral thesis in European integration for the biennium 2004-2005 (14th edition), 18 April of 2007
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