PERFIL CLÍNICO-EPIDEMIOLÓGICO E AVALIAÇÃO PÓS-OPERATÓRIA E PERINATAL DE PACIENTES SUBMETIDAS À MIOMECTOMIA DURANTE A GESTAÇÃO / CLINICAL EPIDEMIOLOGICAL PROFILE AND POST-OPERATIVE AND PERINATAL EVALUATION OF PATIENTS THAT UNDERWENT MYOMECTOMY DURING PREGNANCY

Introdução: O leiomioma é o tumor benigno do músculo liso mais frequente no sexo feminino, podendo apresentar crescimentodurante a gestação em até metade dos casos. A miomectomia neste período pode ser realizada em casos selecionados,porém se observa uma escassez de publicações sobre o tema. Objetivos: Avaliar o perfil clínico-epidemiológico, resultadospós-operatório e perinatais de pacientes submetidas à miomectomia na Unidade Materno Infantil do Hospital Universitário daUniversidade Federal do Maranhão (HUMI-UFMA) no período de 2005 a 2013. Métodos: Trata-se de um estudo descritivo,retrospectivo, de caráter exploratório com abordagem quantitativa. Foram incluídas todas as gestantes submetidas a miomectomiae que fizeram acompanhamento pré-natal no ambulatório de Miomatose e Gravidez no período de 2005 a 2013 no HUMIUFMA.As variáveis maternas e neonatais foram obtidas por revisão dos prontuários e ficha pré-natal. Foram pesquisadas intercorrênciasno transoperatório e pós-operatório. Foram analisadas características do parto, resultados perinatais e suas intercorrências.Resultados: Foram identificadas 12 gestantes submetidas à miomectomia. A idade média foi de 35,5 anos, a corparda foi predominante, as primíparas foram responsáveis por 66,7% dos casos. A idade gestacional na miomectomia foi frequentementeo segundo trimestre (83,3%). A indicação em todas as pacientes foi dor intratável. As pacientes evoluíram bem notransoperatório e pós-operatório. Não houve perda fetal, parto prematuro ou aborto. O índice de cesárea foi de 100%. Todos osrecém-nascidos tiveram Apgar entre 9-10. Conclusão: A maioria das mulheres se autodeclararam pardas e eram primíparas.A intervenção ocorreu em sua maioria no segundo trimestre, devido ao aumento acelerado do volume uterino é a presença dedor. Não houve intercorrências durante a cirurgia, e casos de abortamento ou partos prematuros.Palavras-chave: Leiomiomas Uterinos. Miomectomia na gestação. Pós-operatório. Perinatal.AbstractIntroduction: The myoma is the most frequent benign tumor of the smooth muscle among women can grow during the pregnancyin 50% of all cases. The myomectomy in this period can be done in selected cases; however little publication has been doneis this matter. Objectives: Analyse the clinical and epidemiological profile, post-operation and perinatal results of the patientsundergoing myomectomy, in the Materno Infantil University Hospital (HUMI) in the period of 2005-2013. Methods: This is astudy of exploratory retrospective descriptive nature with quantitative approach. It were included all pregnant women that didtheir pre-natal follow up in the Myomatosis and Pregnancy clinic in the period of 2003 through 2015 in the HUMI. The maternaland neonatal variables were obtained through the records and pre natal file. Complications were surveyed during surgery andin the postoperative. The features of the labor, perinatal results and their complications were analyzed. Results: There were 12pregnant women that underwent trough myomectomy. The average age was 35,5 years old, brown women were the mostcases, and 66,7% of all cases were in woman that were having their first child. In 83,3% of all myomectomies happened in thesecond trimester. The indication of surgery in all patients was the incurable pain. The patients had good outcomes in the operatingroom and in the post operatory. There were no fetal losses, premature birth or abortions. All births were through cesarean.All the newborns had APGAR score between 9-1. Conclusion: this study brought as conclusion that the epidemiological profilewas constituted of white women in their first pregnancy. The intervencion occurred mostly in the second trimester, due to thegrowth of the uterus size associated with non controllable pain. There were no complications during surgery, neither abortionsor need for rapprochement. No premature birth was registred.Keywords: Uterine leiomyomas. Miomectomy during pregnancy. Post operatory. perinatal

Characterisation of microbial attack on archaeological bone

As part of an EU funded project to investigate the factors influencing bone preservation in the archaeological record, more than 250 bones from 41 archaeological sites in five countries spanning four climatic regions were studied for diagenetic alteration. Sites were selected to cover a range of environmental conditions and archaeological contexts. Microscopic and physical (mercury intrusion porosimetry) analyses of these bones revealed that the majority (68%) had suffered microbial attack. Furthermore, significant differences were found between animal and human bone in both the state of preservation and the type of microbial attack present. These differences in preservation might result from differences in early taphonomy of the bones. © 2003 Elsevier Science Ltd. All rights reserved