¿Cómo han evolucionado los museos desde el punto de vista didáctico?

Este trabajo de fin de grado (TFG) tiene como fin recopilar la bibliografía necesaria para extraer las ideas principales que han manifestado diferentes autores/as acerca de cómo han evolucionado los museos a lo largo de la historia haciendo especial hincapié en la evolución didáctica que ha tenido lugar en estas instituciones y su relevancia. Para ello, se mostrará en primer lugar un recorrido histórico que abarcará desde la creación de los museos hasta los cambios que provocó la Nueva Museología en estas instituciones a partir de los años 70. Seguidamente, se indagará acerca de la importancia de la educación dentro de los museos y en cómo se ha ido introduciendo en estos espacios a través de los departamentos educativos. Finalmente, se mostrarán los resultados en cuanto a la evolución didáctica de los museos destacando el papel que han tenido las herramientas tecnológicas en este proceso.This Bachelor´s degree final project aims to collect the necessary bibliography to extract the main ideas expressed by different authors about how museums have evolved throughout history highlighting the didactic evolution in these institutions and their relevance. For this, it will be displayed in the first place a historical tour that will cover from the creation of the museums to the changes caused by the New Museology in these institutions from the 70s. Next, it will inquire about the importance of education within museums and how it has been introduced into these spaces’ trough the educational departments. Finally, the results will be shown in term of didactic evolution of museums highlighting the role that technological tools have had in this process

Desarrollo de una estación meteorológica mediante Raspberry Pi con predicción del tiempo.

En este proyecto se realiza el diseño de una estación meteorológica doméstica que, además de incluir las funcionalidades básicas que se esperan de estos dispositivos relativas al conocimiento de las condiciones meteorológicas, permita al usuario una monitorización más completa del entorno local y de las variables que definen dichas condiciones en un punto geográfico concreto. Se han trabajado especialmente tres aspectos: el diseño de una interfaz gráfica que proporciona información sobre las condiciones actuales del entorno (temperatura y estado del cielo) sin necesidad de acceder a un servidor web, el pronóstico del tiempo local (basado en las medidas recogidas por la propia estación) y la creación de una plataforma, vinculada a internet, que almacena y muestra toda la información recogida y generada.<br /

Genotoxicity of Copper and Nickel Nanoparticles in Somatic Cells of Drosophila melanogaster

Copper and nickel nanoparticles (Cu-NPs and Ni-NPs, respectively) are used in a variety of industrial applications, such as semiconductors, catalysts, sensors, and antimicrobial agents. Although studies on its potential genotoxicity already exist, few of them report in vivo data. In the present study we have used the wing-spot assay in Drosophila melanogaster to determine the genotoxic activity of Cu-NPs and Ni-NPs, and these data have been compared with those obtained with their microparticle forms (MPs). Additionally, a complete physical characterization of NPs using transmission electronic microscopy (TEM), dynamic light scattering (DLS), and laser Doppler velocimetry (LDV) techniques was also performed. Results obtained with Cu-NPs and Cu-MPs indicate that both failed to induce an increase in the frequency of mutant spots formation in the wings of the adults, suggesting a lack of genotoxicity in somatic cells of D. melanogaster. However, when Ni-NPs and Ni-MPs were evaluated, a significant increase of small single spots and total mutant spots was observed only for Ni-NPs (P<0.05) at the highest dose assessed. Thus, the genotoxicity of Ni-NPs seem to be related to their nanoscale size, because no genotoxic effects have been reported with their microparticles and ions. This study is the first assessing the in vivo genotoxic potential of Cu-NPs and Ni-NPs in the Drosophila mode

Comprehensive approach to peritoneal dialysis-related peritonitis by enteric microorganisms: comparison between single organism and polymicrobial infections

[Abstract] Background: Peritoneal infections of enteric origin (EntP) have been classically investigated using partial strategies, focused on particular subgroups of microorganisms. A more comprehensive approach may facilitate the definition of the nomenclature and clinical presentation of these infections. Objectives: To investigate the clinical presentation and outcomes of a full spectrum of EntP, with a particular interest in the comparison between single-organism and polymicrobial infections. Method: Following an observational design, we investigated 165 single-organism and 83 polymicrobial peritonitis episodes with isolation of at least 1 enteric bacteria (Enterobacteriaceae, Enterococcus spp. and/or intestinal anaerobics). We compared the risk of treatment failure for these 2 types of infection and explored the significance of the isolation of specific microorganisms and of their antibacterial susceptibility patterns. Results: Polymicrobial EntP was associated with higher rates of hospitalization, more changes to initial antibiotic therapy, more surgical explorations, and higher mortality and treatment failure rates than monobacterial EntP. However, stratified and multivariate analyses revealed that the burden of these differences rested on the isolation of intestinal anaerobics (odds ratio [OR] 12.05, 95% confidence interval [CI] 2.53–31.09, p < 0.001) and/or Enterococcus faecium (OR 3.37, 95% CI 1.02–11.30, p = 0.046), while other polymicrobial infections were more comparable with single-organism peritonitis, except for even higher mortality rates in the former group. Lower antibiotic susceptibility of the isolations (OR 1.18, 95% CI 0.51–2.70, p = 0.70) did not perform as a predictor of treatment failure. Conclusion: A comprehensive approach to peritoneal infections by intestinal microorganisms may provide a focused perspective of the clinical presentation and outcomes of these complications of peritoneal dialysis

Inhibition of gastric acid secretion by H2 receptor antagonists associates a definite risk of enteric peritonitis and infectious mortality in patients treated with peritoneal dialysis

[Abstract] Background. Evidences linking treatment with inhibitors of gastric acid secretion (IGAS) and an increased risk of serious infections are inconclusive, both in the population at large and in the particular case of patients with chronic kidney disease. We have undertaken an investigation to disclose associations between treatment with IGAS and infectious outcomes, in patients undergoing chronic Peritoneal Dialysis (PD). Method. Observational, historic cohort, single center design. Six hundred and ninety-one patients incident on PD were scrutinized for an association among treatment with IGAS (H2 antagonists H2A or proton pump inhibitors PPI) (main study variable), on one side, and the risks of enteric peritoneal infection (main outcome), overall peritoneal infection, and general and infectious mortality (secondary outcomes). We applied a three-step multivariate approach, based on classic Cox models (baseline variables), time-dependent analyses and, when appropriate, competing risk analyses. Main results. The clinical characteristics of patients treated with H2A, PPI or none of these were significantly different. Multivariate analyses disclosed a consistently increased risk of enteric peritonitis in patients treated with IGAS (RR 1.65, 95% CI 1.08–2.55, p = 0.018, Cox). Stratified analysis indicated that patients treated with H2A, rather than those on PPI, supported the burden of this risk. Similar findings applied for the risk of infectious mortality. On the contrary, we were not able to detect any association among the study variables, on one side, and the general risks of peritonitis or mortality, on the other. Conclusions. Treatment with IGAS associates increased incidences of enteric peritonitis and infectious mortality, among patients on chronic PD. The association is clear in the case of H2A but less consistent in the case of PPI. Our results support the convenience of preferring PPI to H2A, for gastric acid inhibition in PD patients

¿Existe relacion entre los parametros de composicion corporal y el riesgo de infección peritoneal (IP) en dialisis peritoneal (DP)?: estudio longitudinal

Resumen de comunicación ora

Bathyal megabenthic assemblages in the SE Iberian Peninsula (Western Mediterranean Sea)

The Iberian SE is an interesting transition and connectivity zone between the Alboran Sea and the Algerian-Balearic basin. It hosts important deep water fisheries targeting mostly red shrimp (Aristeus antennatus). The area comprises a complex system of tectonic canyons (Mazarron Escarpment), seamounts, knolls and hills (Palos, Planazo, Plis-Plas), and pockmark fields (Acosta et al., 2013). Few studies have been conducted on the bathyal megabenthos, unlike in the neighbouring Chella Bank (De la Torriente et al. 2018) and Balearic Islands (Massuti et al. 2022). The LIFE IP Intemares project is filling this gap

Characterization of Patients With Lupus Nephritis Included in a Large Cohort From the Spanish Society of Rheumatology Registry of Patients With Systemic Lupus Erythematosus (RELESSER)

The aim of the study was to profile those patients included in the RELESSER registry with histologically proven renal involvement in order to better understand the current state of lupus nephritis (LN) in Spain. RELESSER-TRANS is a multicenter cross-sectional registry with an analytical component. Information was collected from the medical records of patients with systemic lupus erythematosus who were followed at participating rheumatology units. A total of 359 variables including demographic data, clinical manifestations, disease activity, severity, comorbidities, LN outcome, treatments, and mortality were recorded. Only patients with a histological confirmation of LN were included.We performed a descriptive analysis, chi-square or Student?s t tests according to the type of variable and its relationship with LN. Odds ratio and confidence intervals were calculated by using simple logistic regression. LN was histologically confirmed in 1092/3575 patients (30.5%). Most patients were female (85.7%), Caucasian (90.2%), and the mean age at LN diagnosis was 28.4 12.7 years. The risk for LN development was higher in men (M/F:47.85/30.91%, P<0.001), in younger individuals (P<0.001), and in Hispanics (P¼0.03). Complete response to treatment was achieved in 68.3% of patients; 10.35% developed ESRD, which required a kidney transplant in 45% of such cases. The older the patient, the greater was the likelihood of complete response (P<0.001). Recurrences were associated with persistent lupus activity at the time of the last visit (P<0.001) and with ESRD (P<0.001). Thrombotic microangiopathy was a risk factor for ESRD (P¼0.04), as for the necessity of dialysis (P¼0.01) or renal transplantation (P¼0.03). LN itself was a poor prognostic risk factor of mortality (OR 2.4 [1.81?3.22], P<0.001). Patients receiving antimalarials had a significantly lower risk of developing LN (P<0.001) and ESRD (P<0.001), and responded better to specific treatments for LN (P¼0.014). More than two-thirds of the patients with LN from a wide European cohort achieved a complete response to treatment. The presence of positive anti-Sm antibodies was associated with a higher frequency of LN and a decreased rate of complete response to treatment. The use of antimalarials reduced both the risk of developing renal disease and its severity, and contributed to attaining a complete renal response

Evaluación del manejo del dolor postquirúrgico en pacientes adultos de una clínica de tercer nivel de Pereira Colombia

El dolor es la primera manifestación clínica del postoperatorio. El objetivo del presente trabajo es evaluar el nivel de dolor percibido por pacientes adultos en el postquirúrgico mediante una Escala Visual Analógica en la Clínica Los Rosales de Pereira

DOCument Scraping for Student Research: From Documents to Knowledge

Laboratorio de enseñanza-aprendizaje-proinvestigación para incentivar la vocación investigadora mediante la inmersión en procesos de extracción de datos (scraping), fomento de capacidades transversales y métodos de la investigación científica, en el ámbito de las Ciencias de la Documentació