66 research outputs found

    Study of Bc+B_c^+ decays to the K+Kπ+K^+K^-\pi^+ final state and evidence for the decay Bc+χc0π+B_c^+\to\chi_{c0}\pi^+

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    A study of Bc+K+Kπ+B_c^+\to K^+K^-\pi^+ decays is performed for the first time using data corresponding to an integrated luminosity of 3.0 fb1\mathrm{fb}^{-1} collected by the LHCb experiment in pppp collisions at centre-of-mass energies of 77 and 88 TeV. Evidence for the decay Bc+χc0(K+K)π+B_c^+\to\chi_{c0}(\to K^+K^-)\pi^+ is reported with a significance of 4.0 standard deviations, resulting in the measurement of σ(Bc+)σ(B+)×B(Bc+χc0π+)\frac{\sigma(B_c^+)}{\sigma(B^+)}\times\mathcal{B}(B_c^+\to\chi_{c0}\pi^+) to be (9.83.0+3.4(stat)±0.8(syst))×106(9.8^{+3.4}_{-3.0}(\mathrm{stat})\pm 0.8(\mathrm{syst}))\times 10^{-6}. Here B\mathcal{B} denotes a branching fraction while σ(Bc+)\sigma(B_c^+) and σ(B+)\sigma(B^+) are the production cross-sections for Bc+B_c^+ and B+B^+ mesons. An indication of bˉc\bar b c weak annihilation is found for the region m(Kπ+)<1.834GeV ⁣/c2m(K^-\pi^+)<1.834\mathrm{\,Ge\kern -0.1em V\!/}c^2, with a significance of 2.4 standard deviations.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2016-022.html, link to supplemental material inserted in the reference

    The Parkinson's Disease-Linked Protein DJ-1 Associates with Cytoplasmic mRNP Granules During Stress and Neurodegeneration.

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    Mutations in the gene encoding DJ-1 are associated with autosomal recessive forms of Parkinson's disease (PD). DJ-1 plays a role in protection from oxidative stress, but how it functions as an "upstream" oxidative stress sensor and whether this relates to PD is still unclear. Intriguingly, DJ-1 may act as an RNA binding protein associating with specific mRNA transcripts in the human brain. Moreover, we previously reported that the yeast DJ-1 homolog Hsp31 localizes to stress granules (SGs) after glucose starvation, suggesting a role for DJ-1 in RNA dynamics. Here, we report that DJ-1 interacts with several SG components in mammalian cells and localizes to SGs, as well as P-bodies, upon induction of either osmotic or oxidative stress. By purifying the mRNA associated with DJ-1 in mammalian cells, we detected several transcripts and found that subpopulations of these localize to SGs after stress, suggesting that DJ-1 may target specific mRNAs to mRNP granules. Notably, we find that DJ-1 associates with SGs arising from N-methyl-D-aspartate (NMDA) excitotoxicity in primary neurons and parkinsonism-inducing toxins in dopaminergic cell cultures. Thus, our results indicate that DJ-1 is associated with cytoplasmic RNA granules arising during stress and neurodegeneration, providing a possible link between DJ-1 and RNA dynamics which may be relevant for PD pathogenesis

    Measurement of the B0s →J/ψη lifetime

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    Using a data set corresponding to an integrated luminosity of 3 fb−1, collected by the LHCb experiment in pp collisions at centre-of-mass energies of 7 and 8 TeV, the effective lifetime in the Bs0→J/ψη decay mode, τeff, is measured to be τeff=1.479±0.034 (stat)±0.011 (syst) ps. Assuming CP conservation, τeff corresponds to the lifetime of the light Bs0 mass eigenstate. This is the first measurement of the effective lifetime in this decay mode

    Measurement of the CKM angle γ\gamma using B0DK0B^0 \rightarrow D K^{*0} with DKS0π+πD \rightarrow K^0_S \pi^+ \pi^- decays

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    A model-dependent amplitude analysis of the decay B0D(KS0π+π)K0B^0\rightarrow D(K^0_S\pi^+\pi^-) K^{*0} is performed using proton-proton collision data corresponding to an integrated luminosity of 3.0fb1^{-1}, recorded at s=7\sqrt{s}=7 and 8TeV8 TeV by the LHCb experiment. The CP violation observables x±x_{\pm} and y±y_{\pm}, sensitive to the CKM angle γ\gamma, are measured to be \begin{eqnarray*} x_- &=& -0.15 \pm 0.14 \pm 0.03 \pm 0.01, y_- &=& 0.25 \pm 0.15 \pm 0.06 \pm 0.01, x_+ &=& 0.05 \pm 0.24 \pm 0.04 \pm 0.01, y_+ &=& -0.65^{+0.24}_{-0.23} \pm 0.08 \pm 0.01, \end{eqnarray*} where the first uncertainties are statistical, the second systematic and the third arise from the uncertainty on the DKS0π+πD\rightarrow K^0_S \pi^+\pi^- amplitude model. These are the most precise measurements of these observables. They correspond to γ=(8022+21)\gamma=(80^{+21}_{-22})^{\circ} and rB0=0.39±0.13r_{B^0}=0.39\pm0.13, where rB0r_{B^0} is the magnitude of the ratio of the suppressed and favoured B0DK+πB^0\rightarrow D K^+ \pi^- decay amplitudes, in a KπK\pi mass region of ±50MeV\pm50 MeV around the K(892)0K^*(892)^0 mass and for an absolute value of the cosine of the K0K^{*0} decay angle larger than 0.40.4.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2016-007.htm

    Observation of the Annihilation Decay Mode <i>B</i><SUP>0</SUP> → <i>K</i><SUP>+</SUP><i>K</i><SUP>-</SUP>

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    A search for the B^{0}→K^{+}K^{-} decay is performed using pp-collision data collected by LHCb. The data set corresponds to integrated luminosities of 1.0 and 2.0  fb^{-1} at center-of-mass energies of 7 and 8 TeV, respectively. This decay is observed for the first time, with a significance of more than 5 standard deviations. The analysis also results in an improved measurement of the branching fraction for the B_{s}^{0}→π^{+}π^{-} decay. The measured branching fractions are B(B^{0}→K^{+}K^{-})=(7.80±1.27±0.81±0.21)×10^{-8} and B(B_{s}^{0}→π^{+}π^{-})=(6.91±0.54±0.63±0.19±0.40)×10^{-7}. The first uncertainty is statistical, the second is systematic, the third is due to the uncertainty on the B^{0}→K^{+}π^{-} branching fraction used as a normalization. For the B_{s}^{0} mode, the fourth accounts for the uncertainty on the ratio of the probabilities for b quarks to hadronize into B_{s}^{0} and B^{0} mesons

    MEASUREMENT OF THE MASS OF THE Z-BOSON AND THE ENERGY CALIBRATION OF LEP

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    The mass of the Z boson has been determined by combining the data from the four LEP experiments ALEPH, DELPHI, L3 and OPAL. The dominant error arises from uncertainties in the calibration of the energy of the beams in LEP. A programme of investigations including energy calibration by resonant depolarization of transversely polarized beams has led to a significant reduction of the uncertainty on the Z mass compared with the precision achieved with the 1990 data. The mass of the Z is measured to be M(Z) = (91.187 +/- 0.007) GeV

    Search for structure in the B-s(0)pi(+/-) invariant mass spectrum

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    The B0sπ± invariant mass distribution is investigated in order to search for possible exotic meson states. The analysis is based on a data sample recorded with the LHCb detector corresponding to 3  fb−1 of pp collision data at s√=7 and 8 TeV. No significant excess is found, and upper limits are set on the production rate of the claimed X(5568) state within the LHCb acceptance. Upper limits are also set as a function of the mass and width of a possible exotic meson decaying to the B0sπ± final state. The same limits also apply to a possible exotic meson decaying through the chain B*0sπ±, B*0s→B0sγ where the photon is excluded from the reconstructed decays
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