27 research outputs found
The clinical relevance of oliguria in the critically ill patient : Analysis of a large observational database
- Author
- Abel P.
- Abella A.
- Abugaber D.
- Achilli C.
- Adib N. A. N.
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2020
- Field of study
Get PDFFunding Information: Marc Leone reports receiving consulting fees from Amomed and Aguettant; lecture fees from MSD, Pfizer, Octapharma, 3 M, Aspen, Orion; travel support from LFB; and grant support from PHRC IR and his institution. JLV is the Editor-in-Chief of Critical Care. The other authors declare that they have no relevant financial interests. Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Urine output is widely used as one of the criteria for the diagnosis and staging of acute renal failure, but few studies have specifically assessed the role of oliguria as a marker of acute renal failure or outcomes in general intensive care unit (ICU) patients. Using a large multinational database, we therefore evaluated the occurrence of oliguria (defined as a urine output 16 years) patients in the ICON audit who had a urine output measurement on the day of admission were included. To investigate the association between oliguria and mortality, we used a multilevel analysis. Results: Of the 8292 patients included, 2050 (24.7%) were oliguric during the first 24 h of admission. Patients with oliguria on admission who had at least one additional 24-h urine output recorded during their ICU stay (n = 1349) were divided into three groups: transient - oliguria resolved within 48 h after the admission day (n = 390 [28.9%]), prolonged - oliguria resolved > 48 h after the admission day (n = 141 [10.5%]), and permanent - oliguria persisting for the whole ICU stay or again present at the end of the ICU stay (n = 818 [60.6%]). ICU and hospital mortality rates were higher in patients with oliguria than in those without, except for patients with transient oliguria who had significantly lower mortality rates than non-oliguric patients. In multilevel analysis, the need for RRT was associated with a significantly higher risk of death (OR = 1.51 [95% CI 1.19-1.91], p = 0.001), but the presence of oliguria on admission was not (OR = 1.14 [95% CI 0.97-1.34], p = 0.103). Conclusions: Oliguria is common in ICU patients and may have a relatively benign nature if only transient. The duration of oliguria and need for RRT are associated with worse outcome.publishersversionPeer reviewe
Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome associated with COVID-19: An Emulated Target Trial Analysis.
- Author
- Abbosh Nathalie
- Abraham Paul
- Achino Chloé
- Ait Oufella Hafid
- Alessandri Claire
- Alexandru Nica
- Amouretti Marc
- Andremont Olivier
- Andreu Pascal
- Anghel Radu
- Annane Djillali
- Argaud Laurent
- Asfar Pierre
- Assefi Mona
- Aubron Cécile
- Aubrun Frédéric
- Auchabie Johann
- Avargues Patrick
- Avenel Alexandre
- Azoulay Elie
- Bajolet Marie-France
- Baldacini Mathieu
- Barbarot Nicolas
- Baron Elodie
- Baudic Thibaut
- Baudry Thomas
- Bavozet Florent
- Bavozet Florent
- Bayle Frédérique
- Beduneau Gaetan
- Begot Emmanuelle
- Beilouny Bassem
- Beloncle François
- Belot Aurélien
- Benchetrit Deborah
- Benhamida Sarah
- Benhamou Michel
- Benzidi Younès
- Bereiziat Marine
- Bergero Nicoletta
- Berteau Florin
- Bertrand Pierre-Jean
- Besse Marie-Catherine
- Beuret Pascal
- Beurton Alexandra
- Beurton Alexandra
- Bigot Christelle
- Bionz Gauthier
- Biston Patrick
- Bitker Laurent
- Blanc Quentin
- Blayau Clarisse
- Blot Rose-Marie
- Bobet Mathieu
- Bodenes Laetitia
- Boiste Fabienne
- Bonnet Nicolas
- Bonnet-Chateau Justine
- Bornstain Caroline
- Bouchet Bruno
- Boudinaud Michel
- Bouglé Adrien
- Bougouin Wulfran
- Bouilland Anne-Laure
- Boukhanza Messabi
- Bouniol François
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- Bouzat Pierre
- Boyer Déborah
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- Bruckert Vincent
- Bruel Cédric
- Bruna Franklin
- Bruneau Amandine
- Bruneel Fabrice
- Brunet Jennifier
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- Cady Julien
- Cailliez Pauline
- Calus Julien
- Canet Emmanuel
- Cantier Marie
- Capellier Gilles
- Cardinale Mickael
- Carenco Lisa
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- Daviet Florence
- de la Chapelle Arnaud
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- Valette Sarah
- van Vong Ly
- Veber Benoit
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- Vivet Bérengère
- Vivier Emmanuel
- Voicu Sébastian
- Voiriot Guillaume
- W. Thille Arnaud
- Weiss Emmanuel
- Weiss Nicolas
- Werner Marie
- Winiszewski Hadrien
- Yvin Elise
- Zafimahazo Daniel
- Zlotnik Diane
- Zylberfajn Cécile
- Publication venue
- 'American Thoracic Society'
- Publication date
- 01/01/2022
- Field of study
Get PDFRATIONALE: Whether COVID patients may benefit from extracorporeal membrane oxygenation (ECMO) compared with conventional invasive mechanical ventilation (IMV) remains unknown. OBJECTIVES: To estimate the effect of ECMO on 90-Day mortality vs IMV only Methods: Among 4,244 critically ill adult patients with COVID-19 included in a multicenter cohort study, we emulated a target trial comparing the treatment strategies of initiating ECMO vs. no ECMO within 7 days of IMV in patients with severe acute respiratory distress syndrome (PaO2/FiO2 <80 or PaCO2 ≥60 mmHg). We controlled for confounding using a multivariable Cox model based on predefined variables. MAIN RESULTS: 1,235 patients met the full eligibility criteria for the emulated trial, among whom 164 patients initiated ECMO. The ECMO strategy had a higher survival probability at Day-7 from the onset of eligibility criteria (87% vs 83%, risk difference: 4%, 95% CI 0;9%) which decreased during follow-up (survival at Day-90: 63% vs 65%, risk difference: -2%, 95% CI -10;5%). However, ECMO was associated with higher survival when performed in high-volume ECMO centers or in regions where a specific ECMO network organization was set up to handle high demand, and when initiated within the first 4 days of MV and in profoundly hypoxemic patients. CONCLUSIONS: In an emulated trial based on a nationwide COVID-19 cohort, we found differential survival over time of an ECMO compared with a no-ECMO strategy. However, ECMO was consistently associated with better outcomes when performed in high-volume centers and in regions with ECMO capacities specifically organized to handle high demand. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/)
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- Yang Shunzhu
- Yang Yanping
- Yang YongXia
- Yao Xiuying
- Yao Yanlan
- Yao Zhiru
- Ye Man
- Ye Mei
- Yeni Nomhle Princess
- Yeon-Joo Lee
- Yildiz İsmail
- Yilmaz Hakan
- Yin Hai
- Yin Li
- Young Charlotte
- Young-Jae Cho
- Yu Jing
- Yu Min
- Yu Tingting
- Yu Zhu Jun
- Yuan Cui
- Yuan Weilian
- Yuan Yuxia
- Yuchen Wu
- Yuemen Ly
- Yumei Chen
- Zahra Hajer Ben
- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
- Zgrzheblovska Lesia
- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
- Zhang Libing
- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- 'Organisation for Economic Co-Operation and Development (OECD)'
- Publication date
- 26/02/2021
- Field of study
Get PDFFunder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
Recommended from our members
Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Abdala Antonio
- Abidi Khalid
- Abillama Fayez François
- Abos Francisco Javier Saenz
- Aboufray Ahmed Ali
- Abregal Giancarlo
- Abroug Fekri
- Achilleos Eleni
- Acosta Ysica
- Adam Višnja Nesek
- Adamina Ileana
- Adams John
- Adamuz Jordi
- Adejumo Prisca Olabisi
- Adekola Oyebola
- Ademokun Jane
- Adenekan Anthony
- Adib Nik Azman Nik
- Adipa Faustina Excel
- Afonso Elsa
- Aganon Ferdinand
- Agarwal Sonika
- Aguirre Joaquin
- Aguirre Lydia Gallego
- Aguirre-Bermeo Hernan
- Ahmad Fatima Kasem El
- Ahmad Meraj
- Ahmed Hazem
- Ahn Jong-Joon
- Ahtiala Maarit
- Akbas Turkay
- Akdağ Devrim
- Akker Mustafa
- Akselsen Gro Ringstad
- Al-Alawi Maram Milud Said
- Alabuzidi Aya
- Alampi Daniela
- Albaiceta Guillermo Muñiz
- Albert Patricia
- Albrecht Lea
- Albrett Jonathan
- Alexandropoulou Paraskevi
- Alexandrou Anna
- Ali Ashwaq
- Ali Mohd Nazri
- Alias Anita
- Alkhumsi Soad Imhmed R.
- Allaert Silvie
- Allison Nicola
- Almekhlafi Ghaleb
- Alonso Helena Fernandez
- Alsheikhly Ahmed Subhy
- Alshrif Abdualhamid I
- Alvarenga Gloria
- Alvarez Diana
- Alvarez Gonzalo Martín
- Alvarez Gustavo Andres
- Alvarez Jorge Duerto
- Alvarez Josep Trenado
- Alvarez Raquel Garcia
- Alves Paulo
- Andersen Marit Hildegunn
- Andersen Yvonne
- Andresen Hanne
- Anisoglou Souzana
- Antonio Maria Gracia San
- Antunes Nelson
- Anvelt Eneli
- Aperocho Cristal April Jane
- Aponte Cesar
- Araya Paola
- Arcas María Luisa Bravo
- Arikan Huseyin
- Arntsen Wenche
- Arteta Arteta Donaldo S.
- Ashour Firas
- Assiri Amer
- Atchade Enora
- Ateya Zainab
- Attwood Ben
- Aucapina Alejandra
- Avalos Fernando
- Aves Emma
- Avogadro Prune
- Avramopoulou Lamprini
- Ay Mustafa
- Ay Serap Avcı
- Aya Umeda
- Ayala Maria
- Aydemir Semih
- Aydin Demet Tok
- Azencot Mazal
- Azoia Joao
- Baasanjav Battsetseg
- Babych Volodymyr
- Baccaro Fernando
- Badariotti Gustavo
- Bae Jung-Min
- Baek Jonghyun
- Baftiu Nehat
- Bagshaw Sean
- Bahrin Laila Kamaliah Kamalul
- Bai Dongmei
- Bai Xiaowu
- Baini Matías
- Bakas Apostolos
- Baker Helen
- Baker Nerilee
- Balasubramanian Madhu
- Balbay Abidin Oner
- Balon Sandrine
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- Banwarie Preveen
- Bao Guijun
- Baptiste-Savoie Jacqueline
- Barakat-Johnson Michelle
- Barefield Cindy
- Barkas Diane
- Barnes Christopher
- Barone Antonio
- Baronia Arvind
- Barr Louise
- Barreiro Emma Moreno
- Barros Elaine
- Barrowcliffe Suzanne
- Barrueco-Francioni Jesus Emilio
- Bartoli Julio Ricardo
- Baruah Rosaleen
- Bascary Carlos Alejandro
- Baskakov Danil
- Baskoro Windu
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- Belii Adrian
- Belkhair Wesal Ali
- Belskiy Vladislav
- Ben-Hamouda Nawfel
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- Benbenishty Julie
- Bench Suzanne
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- Berry Gillian
- Bertoletti Fernando Pablo
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- Besch Guillaume
- Bestle Morten
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- Bhakhtiani Lakshay
- Bhargava Vaibhav
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- Bielskute Egidija
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- Birgisdóttir Hrönn
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- Blanco Maria Pilar Sogues
- Blasco Maria Luisa
- Bliksted Inger Abildgaard
- Blondal Asbjorn
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- Bonaccorso Luciano
- Bongiorno Benjamin
- Bonsignore Pablo Julio Maldonaldo
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- Bowes Bonnie
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- Brett Stephen
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- de Almeida Angelica Olivetto
- de Anda Gilberto Felipe Vazquez
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- de la Ventana Ana Belén Sánchez
- De lange Dylan
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- de Molina Serrano José Ivan Rodriguez
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- De Rosa Silvia
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- Dormans Tom
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- Dragoumanis Christos
- Du Guifang
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- D’Ambrosio Francesco
- D’Ambrosio Paolo
- Ebaid Maie
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- Efe Serdar
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- Efthymiou Anna
- Egi Moritoki
- Egorova Natalya
- Ei Poe Poe
- Elatrous Souheil
- Elay Gülseren
- Elgammudi Mala
- Elhadi Ahmed
- Elhadi Muhammed
- Elhechmi Youssef Zied
- Elkhayari Mina
- Ellazar Chris Gerome
- Eller Philipp
- Eltorai Ashley Szabo
- Enamorado Judy
- Enamorado Judy Enamorado
- Eneas Antony
- Eng Timothy
- Erdivanli Başar
- Erdogan Elif
- Eroglu Ahmet
- Ershova Olga
- Escalante Rosana Gabriela
- Espinosa Cristina Paños
- Esposito Romina
- Essardy Fatiha
- Etourneau Fabienne
- Evers Mirjam
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- Khanna Ashish K.
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- Lajara Miguel Angel Gimenez
- Lajeunesse Jennifer
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- Tuo Lili
- Turan Can
- Turan Sema
- Turc Jean
- Turner Sarah Jane
- Turčan Anton
- Tutillo Diego Rolando Morocho
- Twagirumugabe Theogene
- Twiggs Hilary
- Uba Stella
- Uccelli Francesco
- Udiljak Nikolina
- Ugwu Innocent
- Umek Nejc
- Undar Hasan Nabi
- Vakalos Aristeidis
- Valerio Idália
- Valgolio Emanuel
- Valta Maija
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- van Axel Alisha
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- Van Vliet Peter
- Vanroest Margijske
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- Villafuerte Missael Vladimir Espinoza
- Villanueva Ximena
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- Vlaovic Janko
- Vochin Ana
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- von der Osten Ingrid
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- Wahab Sherliza
- Wahlbom Ewa
- Waibel Hansjoerg
- Wallin Ewa
- Walsh Amy
- Wan Jianhong
- Wan Yan
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- Wang Jing
- Wang Kefang
- Wang LingLing
- Wang RuiXia
- Wang Shuhui
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- Wang Wenmei
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- Wang Ying
- Wang Yingli
- Wang Yuping
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- Waweru-Siika Wangari
- Wei Dongfang
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- Wei Xiyan
- Wei Ying
- Welters Ingeborg D.
- White Joanne
- White Nigel
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- Wiborg Elisabeth
- Wijnands Patricia
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- Williams Ged
- Williams Helen
- Williams Karen
- Williams Lynne
- Wilting Rob
- Wise Robert
- Woods Justin
- Wright Kerry
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- Wu Xiaojun
- Wu Xiaoying
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- Wu Yun
- Wu Zijing
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- Xia Chun Jie
- Xia Xinhua
- Xiao Lina
- Xiao Min
- Xiao Yan
- Xiaoyan Yang
- Xie Yan
- Xing Cynthia
- Xiong Yunfeng
- Xixi Li
- Xu Lina
- Xu Xiao
- Xu Xuelian
- Xu Yan
- Xue Xiujuan
- Yaghi Aktham
- Yakubu Yakubu H.
- Yamamoto Ryohey
- Yan Howe
- Yan Xiaoli
- Yan Yan
- Yang Fan
- Yang Fengling
- Yang Huai
- Yang Jing
- Yang Lei
- Yang Qiao
- Yang Shunzhu
- Yang Yanping
- Yang YongXia
- Yao Xiuying
- Yao Yanlan
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- Yildiz İsmail
- Yilmaz Hakan
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- Zahra Hajer Ben
- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
- Zgrzheblovska Lesia
- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
- Zhang Libing
- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- Intensive Care Medicine
- Publication date
- 09/04/2021
- Field of study
Get PDFThe original version of this article unfortunately contained a mistake
Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Aaron Joffe
- Aaron Mark Hernandez
- Aaron Mark Hernandez
- Abby Lewis
- Abdelhamid Hachimi
- Abdualhamid I Alshrif
- Abel Viveiros
- Abhijit Duggal
- Abidin Oner Balbay
- Achilleas Chovas
- Ade Susanti
- Adi Hadzibegovic
- Adonis Dungca
- Adrian Belii
- Adrian Belii
- Adriana Onelli
- Afolabi Owojuyigbe
- Agnieszka Kubisz-Pudelko
- Agnès Blanc
- Ahmed Ali Aboufray
- Ahmed Elhadi
- Ahmed Ramadan Triki
- Ahmed Subhy Alsheikhly
- Ahmed Zaki
- Ahmet Eroglu
- Aidan O'Shea
- Aikaterini Dimoula
- Aikaterini Efthimiou
- Aikaterini Flevari
- Ailesh Corcoran
- AiPing Bi
- Aiua Ren
- Aizhi Zhang
- Ajitha Rajendran
- Akemi Hirao
- Akira Ohuchi
- Aktham Yaghi
- Ala Khaled
- Alan Sustic
- Alan Sustic
- Alba Riera
- Alban Greca
- Alberto de Jesús Ortiz
- Alberto Peratoner
- Alejandra Aucapina
- Alejandra Azahara Marguello Fernandez
- Alejandro Ibarra
- Aleksandar Šuput
- Aleksandra Gutysz-Wojnicka
- Alessandra Negro
- Alessandro Di Risio
- Alessandro Galazzi
- Alexander Dullenkopf
- Alexander Kiselev
- Alexander Tsarev
- Alexandra Pivkina
- Alexandra Vasquez
- Alexis Tabah
- Ali Kağnıcı
- Alida Moise
- Aline Ramalho
- Alinoy Lavy
- Alisha van Axel
- Alma Cani
- Alvaro Ortega Guerrero
- Amalia Corso
- Amber Markham
- Amelia Ferreira
- Amer Assiri
- Amilcar Garcia
- Amilcar Garcia
- Amit Gupta
- Amit Gupta
- Amy Collins
- Amy Thompson
- Amy Walsh
- Amylkar Garay Reyes
- Amylkar José Garay Reyes
- Ana Alabart Llinas
- Ana Alícia Velarde Pineda
- Ana Bantar
- Ana Belén Curto Polo
- Ana Belén Sánchez de la Ventana
- Ana Diaz
- Ana Diaz
- Ana Isabel Clement
- Ana Laura Gonzalez
- Ana Lucia Vitti Ronchini
- Ana Margarida Feranandes
- Ana María De Pablo
- Ana Pascual-Bielsa
- Ana Tavares
- Ana Vochin
- Ana Wensell Fernández
- Anastasia Spyropoulou
- Anastasio Espejo Cano
- Andeas Stübner
- Andrea Bruni
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Giampaoletti
- Andrea Martonova
- Andrea Martonova
- Andrea McDonnell
- Andrea McLucas
- Andrej Markota
- Andrijan Kartalov
- Andréa Maria Laizner
- Andréa Maria Laizner
- Andréa Maria Laizner
- Ane Stenset
- Angela Trposak
- Angelica Olivetto de Almeida
- Anisette Hoegenhaven
- Anita Alias
- Anita Jans
- Anita Vuković
- Anita-Chrysolyte Kusi-Appiah
- Anja Diers
- Anja Hansen
- Ann-Sofie Malvemyr
- Anna Alexandrou
- Anna Diaz
- Anna Efthymiou
- Anna Kyriakoudi
- Anna Leonova
- Anna Vita Bruno
- Anne Fishman
- Anne Langvad
- Anne Marie Kodal
- Anne Sofie Bomholt Pedersen
- Anne Williams
- Anne-Sophie Debue
- Annette Carey
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- Min Xiao
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- Mina Elkhayari
- Mina Mathaios
- Minna Peltomaa
- Miquel Sanz
- Mireia Llaurado-Serra
- Mireia Llaurado-Serra
- Mirjam Evers
- Mirjana Shosholcheva
- Mirjana Shosolcheva
- Miroslaw Czuczwar
- Misa Fister
- Missael Vladimir Espinoza Villafuerte
- Mohamed Abdurazzag Ali Ghula
- Mohamed Benlamin
- Mohan Gurjar
- Mohan Gurjar
- Mohd Basri Mat Nor
- Mohd Nazri Ali
- Mohd Zulfakar Mazlan
- Mohd Zulfakar Mazlan
- Mona Ringdal
- Monica Adriana Scutariu
- Monica Garcia Diaz
- Monica Gomez
- Monica Popescu
- Monica Recio Losilla
- Monica Rocco
- Monika Rothenfusser
- Montserrat Venturas Nieto
- Morena Milic
- Moris Rosati
- Moritoki Egi
- Morten Bestle
- Mrina Oikonomou
- Mu Jianhong
- Muhammed Elhadi
- Muhommed Ridwaan Syed
- Mukta Singh
- Murat Emre Tokur
- Muriel Fartoukh
- Mustafa Akker
- Mustafa Ay
- Na Jia
- Na Zhang
- Nadezhda Zubareva
- Nadine Flessel
- Nafseen Mostafa
- Nafseen Mostafa
- Nahla Ismail
- Nancy Hernandez-Sanchez
- Naraindath N Boedjawan
- Natalia Franco
- Natalia Hagau
- Natalia Monges
- Natalie Fox
- Natalie Remor
- Natalya Egorova
- Nathalie Fox
- Nathalie Gautheret
- Nathalie Heitzler
- Nawfel Ben-Hamouda
- Nayeli Rocio Cañas Padilla
- Nebia Peker
- Nehat Baftiu
- Neil Smith
- Nejc Umek
- Nelson Antunes
- Nerilee Baker
- Nestor Caicedo
- Neus Calpe
- Ngu Pei Hua
- Nicola Allison
- Nicola Horrigan
- Nicola McCann
- Nicola Vaughan-Jones
- Nicolas De Schryver
- Nie Bocui
- Niels Van Regenmortel
- Nigel White
- Nik Azman Nik Adib
- Nika Zorko
- Nikita Matiushkov
- Nikki Sarkar
- Nikolaj Kamenshchikov
- Nikolaos Kakaras
- Nikolaos Kazakos
- Nikolaos Pantelas
- Nikolina Udiljak
- Nina Kolbe
- Ning Li
- Nisha Bhandari Subedi
- Nivisha Parag
- Nobuaki Shime
- Noelia Rivas
- Nomhle Princess Yeni
- Nordian Xhindi
- Noryani Mohd Samat
- Noushin Taghavi
- Nurdan Ünlü
- Nurulhuda Binti A Manap
- Oksana Zueva
- Oktay Demirkiran
- Olakunle Idowu
- Olga Ershova
- Olga Farre
- Olga Ignatenko
- Oliva Matrona
- Orla Smith
- Osama Wanees Emhemid Tababa
- Oscar Fernandez
- Oscar Fernández Rostello
- Oscar Oiting
- Ourania Mousafiri
- Outi Kauppi
- Oyebola Adekola
- Oyebola Adekola
- Ozcengiz Dilek
- Ozlem Ozkan Kuscu
- Pablo Garcia Olivares
- Pablo Julio Maldonaldo Bonsignore
- Pablo Lopez-Arcas Calleja
- Pablo Monedero
- Pablo Saul
- Pamela Rocha
- Panagiotis Ioannides
- Paola Araya
- Paolo Ciorba
- Paolo Cortellazi
- Paolo D'Ambrosio
- Paraskevi Alexandropoulou
- Pascal Beuret
- Pasquale Iozzo
- Patricia Albert
- Patricia Brizuela
- Patricia Delgado
- Patricia Gordon
- Patricia Wijnands
- Patrick Biston
- Patrick M Honore
- Patrick M Honore
- Patrick M Honoré
- Patrick Meybohm
- Patrick Toppin
- Paul Caddell
- Paul Eric Reyes
- Paul Hayden
- Paul Kuijpers
- Paul Pulak
- Paula Cabrita
- Paula Cristina Nogueira
- Paula Villegas
- Pauline Fivecoat
- Paulo Alves
- Paulo Carlos Garcia
- Pavlina Kleanthous
- Pedro Gutierrez
- Pedro Mogrovejo
- Pedro Silva
- Penny Parsons
- Peter Creber
- Peter Delve
- Peter Firment
- Peter Marko
- Peter Van Vliet
- Petr Piza
- Petra Crone
- Petra Polgarova
- Phil Broadhurst
- Philipp Douschan
- Philipp Eller
- Philipp Eller
- Philipp Simon
- Philippe Montravers
- Phumele Jali
- Pia Molina
- Pierina Arias Campos
- Pieter Hoste
- Pilar Martinez
- Pina Migliorino
- Pınar Karabacak
- Poe Poe Ei
- Poon Shing Tak
- Prabha Gautam
- Prabha Gautam
- Preveen Banwarie
- Prisca Olabisi Adejumo
- Prune Avogadro
- Przemyslaw Jasiewicz
- Purificacion Sanchez Zamora
- Qi Bo
- Qi Li
- Qi Zeng
- Qian Zhao
- Qiang Lin
- Qiao Yang
- Qin Fei
- Qing Feng Jiao
- Qing Li
- Qingli Zhao
- Qingping Huang
- Qiong Liang
- Qiong Ran
- Qun Xia Jiang
- Rachael Parke
- Rachael Parke
- Rachel Baumber
- Rachel Jarman
- Radmilo Jankovic
- Radmilo Jankovic
- Radmilo Jankovic
- Rafael Gonzalez
- Rafael Sierra
- Rajnish Saha
- Ramanathan Lakshmanan
- Ramon Molina Chueca
- Rand Butcher
- Rannveig J Jonasdottir
- Ranveig Lind
- Raquel Cavaco
- Raquel Garcia Alvarez
- Raquel Jimenez
- Rayanne Santos
- Raysa Cristina Schmidt
- Regina Martinez
- Regina Mulvey
- Reimer Riessen
- Renata Curic Radivojevic
- Reni Jacob
- René Favre
- René Schmutz
- Rhian Bull
- Rica Dagooc
- Ricardo Gregorio
- Richard Lebon
- Richard Whitticase
- Rihard Knafelj
- Rihard Knafelj
- Rik T Gerritsen
- Rima Song
- Rishi Ghosh
- Rita Foss Hargott
- Ritoo Kapoor
- Rob Wilting
- Robert Villa
- Robert Wise
- Roberto Gonzalez
- Rodney Rosalia
- Romina Esposito
- Romina Marconi
- Romuald Hentchoya
- Romuald Hentchoya
- Rong Fen Huang
- Rong Hua Zhao
- Ronghua Zhao
- Rongjun Ling Hu
- Rosa Del Bosque Diez
- Rosa Garcia
- Rosaleen Baruah
- Rosana Gabriela Escalante
- Rosanna Vaschetto
- Rosario Cosano
- Rosario Spina
- Rose Ekama Ilesanmi
- Rose Ilesanmi
- Rose Raizman
- Rosie Reece-Anthony
- Rosina Shayamano
- Ruben Fernandez
- RuiXia Wang
- Ruth Palfrey
- Ryohey Yamamoto
- Ryszard Gawda
- Sabah Abu Shawish
- Sabina Dhakal Pathak
- Sabrina Pelz
- Saeed Mahmood
- Saira Gomez
- Sait Karakurt
- Salma Kamoun
- Salvatore Girianni
- Salvatore Maurizio Maggiore
- Samantha Hagan
- Samantha North
- Samantha Smith
- San Juan Roman Nandyelly
- Sandra McPherson
- Sandrine Balon
- Sang-Miin Lee
- Sang-Min Lee
- Sanne Mikkelsen
- Santhana Kannan
- Sara Lospitao
- Sarah Bean
- Sarah Brumwell
- Sarah Buckley
- Sarah Farnell-Ward
- Sarah Grotheer
- Sarah Jane Turner
- Sarah Jones
- Sasha Sankar-Maharaj
- Satoru Hashimoto
- Saulius Vosylius
- Savino Spadaro
- Sean Bagshaw
- Sean Bagshaw
- Sean Bagshaw
- Sean Bagshaw
- Sean Bagshaw
- Sebastian Geijer
- Sebastian Schüppel
- Sebastian Stehr
- Sema Turan
- Semih Aydemir
- Senay Goksu
- Seok Chan Kim
- Seok Jeong Lee
- Serap Avcı Ay
- Serdar Efe
- Sergio Reyes Iburrigarro
- Seung Yong Park
- Seval İzdes
- Seyed Mohammadreza Hashemian
- Shaly George
- Shanshan Lv
- Shanthi Ratnam
- Shanthi Ratnam
- Shanti Ratnam
- Shanti Rudra Deva
- Sharon McDowell-Skaines
- Shella Delossantos
- Shelley Schmollgruber
- Sherissa Microys
- Sherliza Wahab
- ShiFen Wu
- Shu Chuan Chang
- Shuchi Kaushik
- Shuhui Wang
- Shumin Jiang
- Shunsuke Taito
- Shunzhu Yang
- Shuo Wang
- Sibel Ocak Serin
- Silvia Angelica Jorge
- Silvia Call Manosa
- Silvia Calvino Günther
- Silvia Calvino-Gunther
- Silvia Calvino-Gunther
- Silvia Chaparro
- Silvia De Rosa
- Silvia Fernandez
- Silvie Allaert
- Silvina Bravo
- Silvio A Ñamendys-Silva
- Simant Jha
- Simeon Olanipekun
- Simeon Olanipekun
- Simon Dolenc
- Simon Mandaroux
- Simon Whiteley
- Simona Casaioli
- Sini John
- Siobhan O'Nuallain
- Siri Hansen
- Sirley Gill
- Siti Rohayah Sulaiman
- Siv Karin Malmin
- Siw Trudvang
- Slobodan Mihaljevic
- So Young Park
- Soad Imhmed R Alkhumsi
- Sofia Dias
- Sofia Kanakaki
- Sofia Putruele
- Sofia Zepoy
- Solenne Ory
- Sonia O Labeau
- Sonia Stiban
- Sonika Agarwal
- Sophie Liu
- Souheil Elatrous
- Souzana Anisoglou
- Srđan Gavrilovic
- Stacey Watts
- Stanislas Ledochowski
- Stefan Goller
- Stefan Schaller
- Stefano Coremans
- Stella Soundoulounaki
- Stella Uba
- Stephan Graeser
- Stephanie Harris
- Stephen Brett
- Stephen J Brett
- Stephen M Pastores
- Stijn I Blot
- Stijn Van de Velde
- Styliani Bastani
- Styliani Kourelea
- Suha Bozbay
- Sun Lijuan
- Sun Zhiping
- Sundaresan Maiyalagan
- Sundaresan Maiyalagan
- Sundaresan Maiyalagan
- Sung Wai Ho
- Sunghoon Park
- Sunthiti Morakul
- Susana Ferreira
- Susana Pinto
- Susanna Hojden
- Susanne Fischer
- Suzana Bianchini
- Suzana Pečenković
- Suzanne Barrowcliffe
- Suzanne Bench
- Swagata Tripathy
- Swagotika Salo
- Sylvi Vullum
- Syragoula Tsikriki
- Sébastien Jochmans
- Sébastien Pili-Floury
- Taha Khaled
- Tai Sun Park
- Takoua Merhabene
- Talia Ben-Jacob
- Tamas Szakmany
- Tamas Vymazal
- Tanja Depuydt
- Tanja Goranovic
- Tao Zan
- Tara Clesi
- Tarek Dendane
- Tarja Tervo-Heikkinen
- Tatiana Patrichi
- Tatjana Beker
- Taís Pantaleao
- Teena Maguire
- Theogene Twagirumugabe
- Theogene Twagirumugabe
- Theonymfi Papavasilopoulou
- Thierry Dugernier
- Thomai Tholioti
- Thomas Dimski
- Thomas Leong
- Thomas Llewellym
- Tianfei Chen
- Ticiane Campanili
- Tien Meng Khoo
- Tim Chimunda
- Timothy Eng
- Tina Charlotte Bitsch Hansen
- Tina Damgaar Thomsen
- Tine Melgaard Frandsen
- Ting Han
- Tingting Li
- Tingting Yu
- Tobias Heinicke
- Tobias Odenthal
- Tobias Schulze
- Tom Dormans
- Tomas Jovaisa
- Tomas Jovaisa
- Tomas Vymazal
- Tomasz Torlinski
- Tomislav Mirkovic
- Tonia Onyeka
- Touraj Rastegar
- Treiza Trueman-Dawkins
- Trina Zhivotneva
- Troy Browne
- Turkay Akbas
- Ulf Guenther
- Ulla Kesti
- Ulla Sandberg
- Ulrica Mickelsson
- Ulrich Jaschinski
- Umeda Aya
- Una Gunter
- Uri Gorokhovatsky
- Uta Kolussi
- V Gusarov
- Vaarisan Ganeshalingam
- Vaibhav Bhargava
- Valentina Bendelari
- Valentina Di Gravio
- Vanda Seromenho
- Vanesa Mercado Telleria
- Vanesa Mercado Telleria
- Vanja Gievski
- Vanja Misic
- Vasileios Bekos
- Vasiliki Chantziara
- Vasilios Koulouras
- Vasilios Koulouras
- Veronica Curilen
- Veronika Kotanidi
- Vesna Bumbasirevic
- Vicent Salvà-Costa
- Victor Gonzalez
- Victoria Houghton
- Victoria Khoronenko
- Victoria Marriott
- Vilas Kushare
- Vincent Castelain
- Vincent Fraipont
- Vincianne Pleitinckx
- Virginie Souppart
- Virpi Lusenius
- Vishnu Das Sasidharan Nair
- Vitaly Gusarev
- Vitaly Gusarov
- Vitor Gomes
- Vitor Manuel Vaz Pinto
- Viveca Hamback Hellkvist
- Višnja Nesek Adam
- Vladimir Gurevich
- Vladimir Kulakov
- Vladislav Belskiy
- Volkan Inal
- Volodymyr Babych
- Vongayi Ogbeide
- W Nazaruddin W Hassan
- Walid Naija
- Walid Sellami
- Walter Swinnen
- Wan Nasrudin Wan Ismail
- Wang Zhijuan
- Wangari Waweru-Siika
- Wangari Waweru-Siika
- Wangyan Jin
- Wei Sun
- Wei Wang
- Wei Wei
- Wei Zhang
- Wei Zhang
- Weilian Yuan
- Weiwei Li
- Wenche Arntsen
- Wendy Brown
- Wendy Chaboyer
- Wendy Chaboyer
- Wendy Milner
- Wenjie Ju
- Wenmei Wang
- Wenmin Chen
- Wenwen Zhao
- Wenzhen Cao
- Wesal Ali Belkhair
- Willem Dieperink
- Windu Baskoro
- Won-Yeon Lee
- Wu Yuchen
- Xia Cui
- Xia Huang
- Xianhong Zheng
- Xianping Luo
- Xiao Fang Tian
- Xiao Xu
- XiaoChun Hu
- Xiaodi Liu
- Xiaofang Luo
- Xiaohan Li
- Xiaohan Li
- Xiaojun Wu
- Xiaoli Yan
- Xiaomin Wang
- Xiaoqiong Deng
- Xiaowu Bai
- Xiaoyan Chen
- Xiaoyan Chen
- Xiaoying Wu
- XiaoZhe Liu
- Ximena Villanueva
- Xingguo Li
- Xinhua Xia
- Xinhua Xia
- Xinjian Li
- Xinran Ding
- Xinxia Li
- Xinxia Li
- Xiuhua Fang
- Xiuhua Fang
- Xiujuan Xue
- XiuMei Liu
- Xiuying Yao
- Xiyan Wei
- Xu Peipei
- Xue Lin
- Xue Qin Li
- Xuejuan Liang
- XueLian Liu
- Xuelian Pang
- Xuelian Xu
- Xueping Jiao
- Yajun Ding
- Yakubu H Yakubu
- Yali Zhang
- Yalım Dikmen
- Yalım Dikmen
- Yalim Dikmen
- Yan Gao
- Yan Li
- Yan Liu
- Yan Liu
- Yan Long
- Yan Wan
- Yan Wang
- Yan Xiao
- Yan Xie
- Yan Xu
- Yan Yan
- Yanfei Long
- Yang Lei
- Yang Liu
- Yang Wu
- Yang Xiaoyan
- Yanhong Di
- Yanhua Hao
- Yani Tian
- Yanlan Yao
- Yanling Shen
- Yanman Jian
- Yanmei Gu
- Yanming Ding
- Yann Le Guen
- Yanping Yang
- Yasser Mandourah
- Yenny Cardenas
- Yenny Cardenas
- Yesim Serife Bayraktar
- Yin He
- Ying Cao
- Ying Li
- Ying Liu
- Ying Wang
- Ying Wei
- Ying Zhang
- Yingjuan Zhao
- Yingli Wang
- Yinhua Guo
- Yolanda Mendiara
- YongXia Yang
- Yoshimasa Nishime
- Yoshiro Hayashi
- Youjin Chang
- Youru Jiang
- Youssef Zied Elhechmi
- Ysica Acosta
- Yu Chao
- Yu Han
- Yu Liu
- Yu Liu
- Yue Sun
- Yue Ying Gong
- Yuming Zhou
- Yun Su Sim
- Yun Wu
- Yunchun Dong
- Yunfeng Xiong
- Yupeng Liu
- Yuping Wang
- Yuxia Huo
- Yuxia Wang
- Yuxia Yuan
- Yvan Fleury
- Yvonne Andersen
- Zainab Ateya
- Zaneta Bogoevska-Miteva
- Zeya Shi
- Zhang Zhigang
- ZhangShuangzi Li
- ZhangXia Feng
- Zhaoxia Feng
- Zhaoxing Dai
- Zhenxia Zhang
- Zhihong Chen
- Zhiru Yao
- Zhixia Jiang
- ZhiXia Jiang
- Zhixia Tian
- Zhu Jun Yu
- Zhuqing Li
- Zied Hajjej
- Zijing Wu
- Zsuzsann Ágoston
- Zu Qing Cao
- Zulkifli Zulkifli
- Ângela Lima
- Publication venue
- Intensive Care Medicine
- Publication date
- 29/08/2020
- Field of study
Get PDFFunder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
ANALYSE DES FLUCTUATIONS DU RAYONNEMENT ATMOSPHERIQUE AUTOUR DE 4,3 MICRONS POUR DES VISEES SATELLITALES PROCHES DU NADIR
- Publication venue
- Publication date
- 01/01/2000
- Field of study
No full textPARIS7-Bibliothèque centrale (751132105) / SudocSudocFranceF
A Simple and Reliable Strategy for BK Virus Subtyping and Subgrouping
- Author
- Publication venue
- 'American Society for Microbiology'
- Publication date
- 01/01/2017
- Field of study
No full textInternational audiencevirus (BKV)-associated diseases in transplant recipients are an emerging issue. However, identification of the various BK virus subtypes/subgroups is a long and delicate process on the basis of currently available data. Therefore, we wanted to define a simple and effective one-step strategy for characterizing all BK virus strains from the VP1 gene sequence. Based on the analysis of 199 available complete DNA VP1 sequences, phylogenetic trees, alignments, and isolated polymorphisms were used to define an effective strategy for distinguishing the 12 different BK virus subtypes/subgroups. Based on the 12 subtypes identified from the 199 complete BKV VP1 sequences (1,089 bp), 60 mutations that can be used to differentiate these various subtypes/ subgroups were identified. Some genomic areas were more variable and comprised mutational hot spots. From a subregion of only 100 bp in the VP1 region (1977 through 2076), we therefore constructed an algorithm that enabled rapid determination of all BKV subtypes/subgroups with 99% agreement (197/ 199) relative to the complete VP1 sequence. We called this domain of the BK viral genome the BK typing and grouping region (BKTGR). Finally, we validated our viral subtype identification process in a population of 100 transplant recipients with 100% efficiency. The new simpler method of BKV subtyping/subgrouping reported here constitutes a useful tool for future studies that will help us to more clearly understand the impact of BKV subtypes/subgroups on diagnosis, infection, and BK virus-associated diseases
BK polyomavirus in the urine for follow-up of kidney transplant recipients
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2019
- Field of study
No full textInternational audienceOBJECTIVES: After kidney transplantation, human BK polyomavirus (BKPyV) can induce a progressive disease, in three stages: viruria, viremia, and then nephropathy after a few months of viral replication. Therapeutic intervention is recommended when BKPyV is detected in the plasma. The objective of our study was to assess urinary BKPyV nucleic acid test as a predictor for developing viremia. METHODS: We first defined a viruria threshold based on 393 time-matched urine and plasma samples collected after kidney transplantation and then to validate this threshold, we followed-up a cohort of 236 kidney transplant patients. RESULTS: A BKPyV viruria threshold of 6.71 log10 copies/mL best discriminated between plasma-positive and plasma-negative patients (sensitivity: 90.9% (95%CI: 86.5-95); specificity: 90.3% (95%CI: 86.3-94.3); area under the curve: 0.953 (95%CI: 0.933-0.974). In the validation cohort, the risk of developing BKPyV viremia at one year was 16.5% (39/236) and rose to 90.7% (39/43) if BKPyV viruria remained above the threshold of 6.71 for more than one month. CONCLUSION: Sustained BKPyV viruria is a reliable, early marker of patients at high risk of developing BKPyV viremia. This marker should alert the clinician early, and thus allow timely therapeutic intervention
The impact of pre-graft serology on the risk of BKPyV infection post-renal transplantation
- Author
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2022
- Field of study
No full textInternational audienceAbstract Objectives BK polyomavirus associated nephropathy, is a troublesome disease induced by BK polyomavirus (BKPyV) infection in immunocompromised renal graft recipients with no effective available treatment, making immunosuppression reduction the only management option. Thus, pre-graft predictive BKPyV replication markers are needed for high-risk viremia patient identification. Methods we conducted a retrospective study to assess the correlation between the BKPyV pre-transplant serostatus and post-transplant BKPyV infection incidence. Sera from 329 recipients and 222 matched donors were tested for anti-BKV antibodies against BKPyV serotypes I and IV by a VLPs-based IgG ELISA, and BKPyV DNA load was monitored for at least 1 year post transplantation. Results 80 recipients were viruric and 59 recipients were viremic post transplantation. In the post-transplant period, the probability of developing viremia for serotype I was increasing from 4.3% for the D-/R + group to 12.1% for the D+/R + group and climbing to 37.5% for the D+/R- group (p < 0.05). When calculating the recipient mean titers for serotypes I and IV, we observed a clear difference in the proportions of viremia passing from 50% for mean titers < 400 to 13.5% for titers ≥ 400 (p < 0.001) with also a higher proportion of presumptive nephropathy (50% vs 23.1%, p < 0.05). In univariate analysis this parameter has an odds ratio of 6.41 for the risk of developing post-transplant BKPyV viremia (95% CI: 3.16–13.07; p < 0.0001). Conclusions Both donor and recipient BKPyV seropositivity determination before transplantation and antibody titer may serve as a predictive tool to manage clinical BKPyV infection by identification of patients at high risk
Effect of anakinra versus usual care in adults in hospital with COVID-19 and mild-to-moderate pneumonia (CORIMUNO-ANA-1): a randomised controlled trial
- Author
- Abad Sebastien
- Ackermann Félix
- Adda Anne
- Adda Mireille
- Aguilar Claire
- Ait Hamou Zakaria
- Alary Stéphanie
- Alby-Laurent Fanny
- Allanic Laure
- Allenbach Yves
- Alyanakian Marie-Alexandra
- Amara Yaël
- Andres Emmanuel
- Anguel Nadia
- Annonay Laurence
- Antignac Marie
- Aratus Gladys
- Archer Gabrielle
- Arlet Jean-Benoit
- Arzoine Jérémy
- Asselate Belkacem
- Aunay Lucie
- Azoulay Elie
- Bachelard Antoine
- Baghli Kamyl
- Bah Aïcha
- Bakouboula Prissile
- Bardou Marc
- Bariz Thinhinane
- Baron Gabriel
- Bastard Jean-Philippe
- Baudry Elodie
- Bayer Sophie
- Becker Guillaume
- Belaube Nicolas
- Belazouz Syllia
- Belilita Ridha
- Bellenfant Florence
- Belloul Mohamed
- Ben-Mabrouk Ines
- Benafla Moustafa
- Benainous Ruben
- Benarab Souad
- Benattia Amira
- Benghanem Sarah
- Benhida Jaouad
- Benoit Philippe
- Benveniste Olivier
- Berard Laurence
- Berbour Férial
- Bergeron Anne
- Bergerot Damien
- Bernard Lise
- Berton Laure
- Bertrand Eliane
- Beurton Alexandra
- Beziriganyan Kristina
- Biard Lucie
- Bienvenu Boris
- Bironne Timothee
- Blanc Frédéric
- Blanchard Anne
- Blanche Philippe
- Blin Emmanuelle
- Bloch Queyrat Coralie
- Boleto Gonçalo
- Bondeelle Louise
- Bonnet Nicolas
- Borie Raphael
- Boudali Yacine
- Bouhris Marion
- Bounhiol Agathe
- Bouras Chaouki
- Bourgoin Alexandre
- Boussard Catherine
- Boutboul David
- Brahmi Sabrina
- Brin Stéphane
- Brindele Isabelle
- Briois Sandrine
- Broissand Christine
- Buffet Alexandre
- Bugnet Emmanuelle
- Bulifon Sophie
- Bureau Côme
- Bureau Serge
- Burger Carole
- Burlacu Ruxandra
- Cacoub Patrice
- Cadranel Jacques
- Cailhol Johann
- Caillat-Zucman Sophie
- Camara-Clayette Valérie
- Campos-Vega Clara
- Camuset Juliette
- Canellas Antony
- Canoui Etienne
- Cardet Kévin
- Carlier Nicolas
- Castelain Vincent
- Cavelot Sébastien
- Celli Lebras Karine
- Chabert Julien
- Chaigne Benjamin
- Chalal Lynda
- Chalal Solaya
- Chambrin-Lauvray Helene
- Champtiaux Nicolas
- Chansombat Malikhone
- Charbonnier Fanny
- Charreteur Robin
- Chas Julie
- Chatelus Emmanuel
- Chatron Eva
- Chauffier Jeanne
- Chavarot Nathalie
- Cheref Kahina
- Chitour Kamil
- Choinier Pascaline
- Cholley Bernard
- Chopin Dorothée
- Choupeaux Laure
- Chousterman Benjamin
- Cisse Mamadou Salif
- Clan Hew Wai Aurélie
- Clarac Ulrich
- Clarke Ada
- Clavere Gaelle
- Clovet Olivier
- Clément Melissa
- Codorniu Anaïs
- Cohen Yves
- Collange Olivier
- Colomba Emeline
- Comarmond Cloé
- Comparon Celine
- Contejean Adrien
- Cordel Hugues
- Cornic Mathias
- Corvol Jean-Christophe
- Costedoat-Chalumeau Nathalie
- Coupez Elisabeth
- Courtin Claire
- Cransac Amélie
- Crespin Paul
- Crestani Bruno
- Cylly Laurent
- d'Ortenzio Eric
- da Silva Rosa
- Daconceicao Olivia
- Daguenel-Nguyen Anne
- Dalibey Sarah
- Danion François
- Darmont Michaël
- Dautel Dominique
- Davoine Claire
- de Blay Frédéric
- de Castro Nathalie
- de Lastours Victoire
- de Sarcus Martin
- Debrix Isabelle
- Decavele Maxence
- Deconinck Laurene
- Defrancq Fanny
- Dehais Mélanie
- Dejean Valérie
- Delaugerre Constance
- Delemazure Julie
- Deleris Robin
- Demerville Lauren
- Demonsant Eric
- Demoule Alexandre
- Denies Fanette
- Denis Blandine
- Derridj Nawal
- Desbois Anne Claire
- Deslée Gaetan
- Dhote Robin
- Diehl Jean-Luc
- Diemunsch Pierre
- Diemunsch Sophie
- Dieude Philippe
- Dieye Thierno
- Djadel Mourad
- Djadi-Prat Juliette
- Djaghout Lalia
- Domont Fanny
- Dossier Antoine
- Dougados Maxime
- Dournon Nathalie
- Dres Martin
- Drouard Laurence
- Drouet Elodie
- Dubert Marie
- Duceau Baptiste
- Duchemann Boris
- Duclos-Vallée Jean-Charles
- Ducrocq Greggory
- Dunogue Bertrand
- Dupin Clairelyne
- Dupland Pierre
- Dupré Celine
- Durand Philippe
- Duranteau Jacques
- Durel - Maurisse Aurélie
- Dusanter Isabelle
- Duée Frédéric
- Ebstein Nathan
- El Amine Younes
- Elisee Virginie
- Emmerich Joseph
- Escaut Lelia
- Estellat Candice
- Fabre Solène
- Fain Olivier
- Fallet Vincent
- Fartoukh Muriel
- Faure Morgane
- Fauvaux Catherine
- Faye Pierre
- Fayol Antoine
- Fellahi Soraya
- Felten Renaud
- Feredj Elsa
- Ferfar Yasmina
- Feyeux Delphine
- Figueiredo Samy
- Fillon Julie
- Flamand Saskia
- Flamarion Edouard
- Fodil Hanane
- Fois Elena
- Fournier Benjamin
- Fourreau Alain
- François Hélène
- Frazier Aline
- Fremont Dimitri
- Fuentes Axelle
- Galicier Lionel
- Gamany Naura
- Gambier Nicolas
- Garcia Gilles
- Garnier Marc
- Gaudefroy Caroline
- Gauzit Remy
- Georgin-Lavialle Sophie
- Geri Guillaume
- Gernez Coralie
- Gervais Anne
- Ghembaza Amine
- Ghosn Jade
- Gilbert Marie
- Gimeno Linda
- Giroux-Leprieur Benedicte
- Godier Anne
- Goichot Bernard
- Gorget Thomas
- Gottenberg Jacques-Eric
- Goupil de Bouille Jeanne
- Grailles Guillaume
- Granville Sophie
- Greigert Valentin
- Grimaldi Lamiae
- Grisot Paul Henri
- Gros Antoine
- Gros Hélène
- Guerin Corinne
- Guffroy Aurélien
- Guidet Bertrand
- Guillaud Constance
- Guillaume-Jugnot Perrine
- Guillot Emmanuelle
- Guinot Pierre-Grégoire
- Gysembergh-Houal Anne
- Hadjam Tassadit
- Hai Dhiaa Meriem
- Hamada Sophie-Rym
- Hamiria Samir
- Hammal Soumeya
- Hansmann Yves
- Harrois Anatole
- Haudebourg Luc
- Hauw-Berlemont Caroline
- Heger Bob
- Henriques Mickael
- Henry Estelle
- Hermine Olivier
- Honsel Vasco
- Hulot Jean-Sébastien
- Humbert Marc
- Hutt Anne
- Isernia Valentina
- Ismael Sophie
- Issorat Elodie
- Jacob Aude
- Jacolot Anne
- Jallouli Moez
- Jambon Julie
- Jaubert Paul
- Jauréguiberry Stéphane
- Jaïs Xavier
- Jegu Anne Lise
- Jesuthasan Denis,
- Jevnikar Mitja
- Joly Veronique
- Joseph Adrien
- Jouany Pauline
- Joumaa Hassan
- Jourdaine Clément
- Jouve Charléne
- Jozwiak Mathieu
- Julia Zelie
- Junquera Ramon
- Kaeuffer Charlotte
- Karachi Carine
- Kassegne Loic
- Kebir Amina
- Kedzia Cécile
- Keo Vixra
- Kerneis Solen
- Keroumi Younes
- Kiouris Elena
- Klasen Alison
- Knosp Camille
- Kolta Sami
- Korganow Anne Sophie
- Koumis Ilias
- Kozaliewicz Ewa
- Krause Le Garrec Jessica
- Lachatre Marie
- Lacombe Karine
- Lafoeste Hélène
- Lambotte Olivier
- Lancon Victor
- Languille Laetitia
- Larcheveque Cecile
- Lariven Sylvie
- Le Borgne Pierrick
- Le Bourlout Catherine
- Le Gac Sylvie
- Le Guen Pierre
- Le Marchand Mathilde
- Le Marec Julien
- Le Pluart Diane
- Le Tiec Clotilde Le Tiec
- Lebeaux David
- Lecomte Laurence
- Lecronier Marie
- Lefebvre Nicolas
- Lefèvre Edouard
- Lefèvre Guillaume
- Legendre Paul
- Legros Marie-Hélène
- Lehir Isabelle
- Lehmann Blandine
- Lelievre Jean-Daniel
- Lemagner Christine
- Lemarié Nadège
- Lemoine Matthieu
- Lengliné Etienne
- Lenoir Olivia
- Leplay Céline
- Leprun Gaël
- Leroux Gaelle
- Lescure F-Xavier
- Licois Marion
- Lim Pascal
- Livrozet Marine
- Liégeon Geoffroy
- London Jonathan
- Lorillon Gwenaël
- Louapre Céline
- Louis Zeina
- Louni Francoise
- Luong Nguyen Liem Binh
- Maalouf Georgina
- Mabrouki Asmaa
- Madelaine Claire
- Madeleine Isabelle
- Mahevas Matthieu
- Mahtal Nassim
- Mameri Lakhdar
- Mamoune Asmaa
- Manivet Philippe
- Marey Jonathan
- Mariani Louise-Laure
- Mariette Xavier
- Marin Nathalie
- Mariotte Eric
- Marquis Eric
- Martel Pascal
- Martin de Frémont Grégoire
- Martin Karine
- Martin Tristan
- Matignon Marie
- Maurer Agnes
- Mayaux Julien
- Mcavoy Chloe
- Meddah Hakim
- Meftali Ramdane
- Megarbane Bruno
- Mekid Yasmina
- Mekinian Arsène
- Mekontso-Dessaps Armand
- Melica Giovanna
- Menage Nathalie
- Mertes Paul Michel
- Messaoudi Yasmine
- Metzger Catherine
- Meunier Jeanne
- Meunier Martine
- Meyer Nicolas
- Michel Marc
- Michon Adrien
- Michot Jean-Marie
- Mirouse Adrien
- Mohebbi Abolfazl
- Molina Jean-Michel
- Molinari Domitille
- Monnet Xavier
- Montani David
- Montlahuc Claire
- Moores Alexandre
- Mora Pierre
- Morawiec Elise
- Morbieu Caroline
- Morel Alexandre
- Morgand Marjolaine
- Morin Florence
- Mourad Jean-Jacques
- Mourvillier Bruno
- Mouthon Luc
- Nadal Marine
- Ndiaye Awa
- Nemlaghi Safaa
- Neuschwander Arthur
- Nguyen Lee
- Nguyen Yann
- Nisand Gabriel
- Nizard Mandy
- Noaillon Mathilde
- Noel Nicolas
- Noll Eric
- Nunes Hilario
- Nyanou Corine
- Oberlin Mathieu
- Ohlmann-Caillard Sophie
- Oksenhendler Eric
- Olivier Olivier
- Ouamri Sabrine
- Oziel Johanna
- Pacanowski Jerome
- Pacheco Claire
- Palmieri Lola-Jade
- Papo Thomas
- Paquet Valérie
- Pari Marie Hélène
- Parisey Marion
- Parrot Antoine
- Patin Florence
- Pattyn Anne
- Pavot Arthur
- Pavy Stéphan
- Peffault de Latour Régis
- Peigney Isabelle
- Pene Frédéric
- Penet Marie-Aude
- Pereira Maria
- Pernin Claire
- Pernot Corinne
- Perrodeau Elodie
- Petit-Hoang Camille
- Phibel Audrey
- Phung Bao
- Pialoux Gilles
- Pierron Cédric
- Planquette Benjamin
- Poindron Vincent
- Poissy Julien
- Pommeret Fanny
- Porcher Raphaël
- Pottecher Julien
- Pouliquen Anne-Lise
- Pourbaix Annabelle
- Pourchet-Martinez Valérie
- Pradon Caroline
- Provitolo Vincent
- Puéchal Oriane
- Rachline Anne
- Rahli Roza
- Raked Nabil
- Ranque Brigitte
- Rathouin Vanessa
- Ravato Sylviane
- Ravaud Philippe
- Razurel Anaïs
- Rech Jean-Simon
- Regent Alexis
- Renaud Stéphane
- Renet Sophie
- Resche-Rigon Matthieu
- Resmini Léa
- Richard Christian
- Richette Pascal
- Rigal Marthe
- Rigolet Aude
- Rioux Christophe
- Riveline Jean-Pierre
- Rolland-Debord Camille
- Roques Anne-Marie
- Rossi Geoffrey
- Roulot Dominique
- Roux Damien
- Rouzaud Claire
- Rozensztajn Nathalie
- Ruch Yvon
- Sabatier Brigitte
- Sacco Emmanuelle
- Sacleux Sophie-Caroline
- Sadaoui Thiziri
- Sakkal Madona
- Saleh-Mghir Samira
- Saliba Faouzi
- Sambin Sara
- Sanchez Olivier
- Saussereau Julien
- Sautereau Aurelie
- Savale Laurent
- Schlemmer Frédéric
- Schmitz David
- Semaille Caroline
- Semerano Luca
- Semri Hala
- Sene Damien
- Senet Patricia
- Servettaz Amélie
- Sguiouar Naima
- Siguier Martin
- Simon Tabassome
- Sitbon Olivier
- Smati Julie
- Soria Angèle
- Soyez-Herkert Loren
- Stan Emilia
- Steg Gabriel
- Stoclin Annabelle
- Suarez Lydia
- Sublon Cédric
- Szwebel Tali-Anne
- Tantet Claire
- Tarhini Hassan
- Tayebi Hakim
- Tazi Abdellatif
- Teboul Jean-Louis
- Terrier Benjamin
- Tharaux Pierre-Louis
- Thibaut Pélagie
- Thiemele Alaki
- Tibi Annick
- Tissieres Pierre
- Toquet Segolene
- Tremorin Marie-Thérèse
- Tréhan Anne
- Tubach Florence
- Tudesq Jean-Jacques
- Urbina Tomas
- Uzunhan Yurdagul
- Uzzan Matthieu
- Valayer Simon
- Vallet Mathilde
- Vallois Dorothee
- Vanhoye Damien
- Vasquez-Ibarra Miguel Alejandro
- Vauboin Pernelle
- Vautier Mathieu
- Vayssettes Marie
- Vermes Paul
- Verny Christiane
- Verstuyft Céline Verstuyft
- Vicaut Eric
- Vieira Matheus
- Vigna Véronique
- Vimpere Damien
- Virlouvet Myriam
- Virolle Sara
- Volle Geoffroy
- Volpe Thomas
- Walter-Petrich Anouk
- Weill François
- Weiss Emmanuel
- Willekens Chistophe
- Wilpotte Celine
- Wynckel Alain
- Yazdanpanah Yazdan
- Yelles Nessima
- Yelnik Cécile
- Zafrani Lara
- Zahrate-Ghoul Aida
- Zaidan Mohamad
- Zarrouk Virginie
- Zerbit Jérémie
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/03/2021
- Field of study
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