71 research outputs found

    A note on completeness of weighted normed spaces of analytic functions

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    [EN] Given a non-negative weight v, not necessarily bounded or strictly positive, defined on a domain G in the complex plane, we consider the weighted space H-v(infinity) (G)of all holomorphic functions on G such that the product v vertical bar f vertical bar is bounded in G and study the question of when such a space is complete under the canonical sup-seminorm. We obtain both some necessary and some sufficient conditions in terms of the weight v, exhibit several relevant examples, and characterize completeness in the case of spaces with radial weights on balanced domains.The first author was partially supported by MTM2013-43540-P and MTM2016-76647-P by MINECO/FEDER-EU and GVA Prometeo II/2013/013. The second author was partially supported by the MINECO/FEDER-EU Grant MTM2015-65792-P. Both authors were partially supported by Thematic Research Network MTM2015-69323-REDT, MINECO, Spain.Bonet Solves, JA.; Vukotic, D. (2017). A note on completeness of weighted normed spaces of analytic functions. Results in Mathematics. 72(1-2):263-279. https://doi.org/10.1007/s00025-017-0696-2S263279721-2Arcozzi, N., Björn, A.: Dominating sets for analytic and harmonic functions and completeness of weighted Bergman spaces. Math. Proc. R. Ir. Acad. 102A, 175–192 (2002)Berenstein, C.A., Gay, R.: Complex Variables, An Introduction. Springer, New York (1991)Bierstedt, K.D., Bonet, J., Galbis, A.: Weighted spaces of holomorphic functions on bounded domains. Mich. Math. J. 40, 271–297 (1993)Bierstedt, K.D., Bonet, J., Taskinen, J.: Associated weights and spaces of holomorphic functions. Stud. Math. 127, 137–168 (1998)Björn, A.: Removable singularities for weighted Bergman spaces. Czechoslov. Math. J. 56, 179–227 (2006)Bonet, J., Domański, P., Lindström, M.: Essential norm and weak compactness of composition operators on weighted Banach spaces of analytic functions. Can. Math. Bull. 42(2), 139–148 (1999)Bonet, J., Vogt, D.: Weighted spaces of holomorphic functions and sequence spaces. Note Mat. 17, 87–97 (1997)Conway, J.B.: Functions of One Complex Variable, Second Edition, Graduate Texts in Mathematics, vol. 11. Springer, New York (1978)Gaier, D.: Lectures on Complex Approximation. Birkhäuser, Boston (1987)Grosse-Erdmann, K.-G.: A weak criterion for vector-valued holomorphic functions. Math. Proc. Camb. Philos. Soc. 136, 399–411 (2004)Hörmander, L.: An Introduction to Complex Analysis in Several Variables. North-Holland, Amsterdam (1979)Horváth, J.: Topological Vector Spaces and Distributions. Addison-Wesley, Reading (1966)Lusky, W.: On weighted spaces of harmonic and holomorphic functions. J. Lond. Math. Soc. 51, 309–320 (1995)Lusky, W.: On the isomorphism classes of weighted spaces of harmonic and holomorphic functions. Stud. Math. 175, 19–45 (2006)Nakazi, T.: Weighted Bloch spaces which are Banach spaces. Rend. Circ. Mat. Palermo 62, 427–440 (2013)Shields, A.L., Williams, D.L.: Bounded projections, duality and multipliers in spaces of analytic functions. Trans. Am. Math. Soc. 162, 287–302 (1971

    Undergraduate medical student perceptions and use of Evidence Based Medicine: A qualitative study

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    <p>Abstract</p> <p>Background</p> <p>Many medical schools teach the principles of Evidence Based Medicine (EBM) as a subject within their medical curriculum. Few studies have explored the barriers and enablers that students experience when studying medicine and attempting to integrate EBM in their clinical experience. The aim of this study was to identify undergraduate medical student perceptions of EBM, including their current use of its principles as students and perceived future use as clinicians.</p> <p>Methods</p> <p>Third year medical students were recruited via email to participate in focus group discussions. Four focus groups were conducted separately across four hospital sites. All focus groups were conducted by the same facilitator. All discussions were transcribed verbatim, and analysed independently by the two authors according to the principles of thematic analysis.</p> <p>Results</p> <p>Focus group discussions were conducted with 23 third-year medical students, representing three metropolitan and one rural hospital sites. Five key themes emerged from the analysis of the transcripts: (1) Rationale and observed use of EBM in practice, (2) Current use of EBM as students, (3) Perceived use of EBM as future clinicians, (4) Barriers to practicing EBM, and (5) Enablers to facilitate the integration of EBM into clinical practice. Key facilitators for promoting EBM to students include competency in EBM, mentorship and application to clinical disciplines. Barriers to EBM implementation include lack of visible application by senior clinicians and constraints by poor resourcing.</p> <p>Conclusions</p> <p>The principles and application of EBM is perceived by medical students to be important in both their current clinical training and perceived future work as clinicians. Future research is needed to identify how medical students incorporate EBM concepts into their clinical practice as they gain greater clinical exposure and competence.</p

    Crystal Structure of a Complex of DNA with One AT-Hook of HMGA1

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    We present here for the first time the crystal structure of an AT-hook domain. We show the structure of an AT-hook of the ubiquitous nuclear protein HMGA1, combined with the oligonucleotide d(CGAATTAATTCG)2, which has two potential AATT interacting groups. Interaction with only one of them is found. The structure presents analogies and significant differences with previous NMR studies: the AT-hook forms hydrogen bonds between main-chain NH groups and thymines in the minor groove, DNA is bent and the minor groove is widened

    Construction of a large scale integrated map of macrophage pathogen recognition and effector systems

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    <p>Abstract</p> <p>Background</p> <p>In an effort to better understand the molecular networks that underpin macrophage activation we have been assembling a map of relevant pathways. Manual curation of the published literature was carried out in order to define the components of these pathways and the interactions between them. This information has been assembled into a large integrated directional network and represented graphically using the modified Edinburgh Pathway Notation (mEPN) scheme.</p> <p>Results</p> <p>The diagram includes detailed views of the toll-like receptor (TLR) pathways, other pathogen recognition systems, NF-kappa-B, apoptosis, interferon signalling, MAP-kinase cascades, MHC antigen presentation and proteasome assembly, as well as selected views of the transcriptional networks they regulate. The integrated pathway includes a total of 496 unique proteins, the complexes formed between them and the processes in which they are involved. This produces a network of 2,170 nodes connected by 2,553 edges.</p> <p>Conclusions</p> <p>The pathway diagram is a navigable visual aid for displaying a consensus view of the pathway information available for these systems. It is also a valuable resource for computational modelling and aid in the interpretation of functional genomics data. We envisage that this work will be of value to those interested in macrophage biology and also contribute to the ongoing Systems Biology community effort to develop a standard notation scheme for the graphical representation of biological pathways.</p

    Myalgic encephalomyelitis/chronic fatigue syndrome and encephalomyelitis disseminata/multiple sclerosis show remarkable levels of similarity in phenomenology and neuroimmune characteristics

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    Lipid, blood pressure and kidney update 2013

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    Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

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    publisher: Elsevier articletitle: Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes journaltitle: Cell articlelink: https://doi.org/10.1016/j.cell.2018.05.046 content_type: article copyright: © 2018 Elsevier Inc

    Acute encephalopathy associated with Campylobacter jejuni enteritis

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    We present for the first time a case of acute encephalopathy in an adult patient induced by Campylobacter jejuni enteritis. Possible pathogenic mechanisms and importance of neuropsychological testing in the assessment of infection-related encephalopathy are discussed
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