Persistent topographic development along a strike-slip fault system: The Mount McKinley restraining bend

The Denali Fault is a major strike-slip fault extending from British Colombia, into western Alaska. Mount McKinley, at 6,114 m, is the highest peak in North America and is located to the south of a bend in the Denali Fault (Fig.1). To the north, at the apex of the bend in the fault, Peters Dome (3,221 m) is the highest peak and north-side peak elevations rapidly decrease moving away from the bend’s apex

Stoffwechsel, Energie und Entropie in Marx‘ Kritik der Politischen Ökonomie: Jenseits des Podolinsky-Mythos (Teil 2)

"Thermodynamische Überlegungen zu Fragen der Energieerhaltung, der entropischen Dissipation durch Reibung sowie zur Wechselwirkung physikalischer Kräfte spielen im ersten Band des Kapital eine zentrale Rolle. Sie finden sich vor allem im Kapitel über Maschinerie und große Industrie, das den zentralen Teil der Marxschen Untersuchung der industriellen Entwicklung im Kapitalismus darstellt...

Stoffwechsel, Energie und Entropie in Marx’ Kritik der Politischen Ökonomie:: Jenseits des Podolinsky-Mythos (Teil 1)

Until recently, most commentators, including ecological Marxists, have assumed that Marx’s historical materialism was only marginally ecologically sensitive at best, or even that it was explicitly anti-ecological. However, research over the last decade has demonstrated not only that Marx deemed ecological materialism essential to the critique of political economy and to investigations into socialism, but also that his treatment of the coevolution of nature and society was in many ways the most sophisticated to be put forth by any social theorist prior to the late twentieth century. Still, criticisms continue to be leveled at Marx and Engels for their understanding of thermodynamics and the extent to which their work is said to conflict with the core tenets of ecological economics. In this respect, the rejection by Marx and Engels of the pioneering contributions of the Ukrainian socialist Sergei Podolinsky, one of the founders of energetics, has been frequently offered as the chief ecological case against them. Building on an earlier analysis of Marx’s and Engels’s response to Podolinsky, this article shows that they relied on an open-system, metabolic-energetic model that adhered to all of the main strictures of ecological economics – but one that also (unlike ecological economics) rooted the violation of solar and other environmental-sustainability conditions in the class relations of capitalist society. The result is to generate a deeper understanding of classical historical materialism’s ecological approach to economy and society – providing an ecological- materialist critique that can help uncover the systemic roots of today’s “treadmill of production” and global environmental crisis

Homiletics as mnemonic practice : collective memory and contemporary Christian preaching, with special reference to the work of Maurice Halbwachs

In his book Twilight Memories Andreas Huyssen (1995) famously described contemporary Western culture as 'a culture of amnesia'. That concern about social memory is evident in many areas of contemporary discourse. Social memory's confabulatory, subjective, and ambiguous nature makes its analysis an arena of conflicting and diverse opinions. Drawing on Maurice Halbwachs' concept of 'collective memory', and its use in more recent sociological studies, this study uses preaching theory and practice as a way of addressing those wider memory concerns in the life of the church. In particular, the profound challenge of memory work to Christianity's insistence on remembrance as the foundation of its authenticity is examined through contemporary homiletic practice. It is argued that, alongside the familiar didactic, cognitive, epistemological and contextual categories employed in preaching practice, the current crisis of memory requires a new emphasis on memory maintenance. Sermons are presented as mnemonic events essential to the ongoing living tradition of the faith.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Junior Recital

List of performers and performances

Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response.

Mechanical signals from the extracellular microenvironment have been implicated in tumor and metastatic progression. Here, we identify nucleoporin NUP210 as a metastasis susceptibility gene for human estrogen receptor positive (ER+) breast cancer and a cellular mechanosensor. Nup210 depletion suppresses lung metastasis in mouse models of breast cancer. Mechanistically, NUP210 interacts with LINC complex protein SUN2 which connects the nucleus to the cytoskeleton. In addition, the NUP210/SUN2 complex interacts with chromatin via the short isoform of BRD4 and histone H3.1/H3.2 at the nuclear periphery. In Nup210 knockout cells, mechanosensitive genes accumulate H3K27me3 heterochromatin modification, mediated by the polycomb repressive complex 2 and differentially reposition within the nucleus. Transcriptional repression in Nup210 knockout cells results in defective mechanotransduction and focal adhesion necessary for their metastatic capacity. Our study provides an important role of nuclear pore protein in cellular mechanosensation and metastasis

Faculty Convocation

Program listing performers and works performe

The relationships between golf and health:A scoping review

OBJECTIVE: To assess the relationships between golf and health. DESIGN: Scoping review. DATA SOURCES: Published and unpublished reports of any age or language, identified by searching electronic databases, platforms, reference lists, websites and from consulting experts. REVIEW METHODS: A 3-step search strategy identified relevant published primary and secondary studies as well as grey literature. Identified studies were screened for final inclusion. Data were extracted using a standardised tool, to form (1) a descriptive analysis and (2) a thematic summary. RESULTS AND DISCUSSION: 4944 records were identified with an initial search. 301 studies met criteria for the scoping review. Golf can provide moderate intensity physical activity and is associated with physical health benefits that include improved cardiovascular, respiratory and metabolic profiles, and improved wellness. There is limited evidence related to golf and mental health. The incidence of golfing injury is moderate, with back injuries the most frequent. Accidental head injuries are rare, but can have serious consequences. CONCLUSIONS: Practitioners and policymakers can be encouraged to support more people to play golf, due to associated improved physical health and mental well-being, and a potential contribution to increased life expectancy. Injuries and illnesses associated with golf have been identified, and risk reduction strategies are warranted. Further research priorities include systematic reviews to further explore the cause and effect nature of the relationships described. Research characterising golf's contribution to muscular strengthening, balance and falls prevention as well as further assessing the associations and effects between golf and mental health are also indicated