8 research outputs found
A novel Alzheimer disease locus located near the gene encoding tau protein
- Author
- A Boland
- A C Naj
- A David Smith
- A Hofman
- A L Destefano
- A L Fitzpatrick
- A M Goate
- A R Laza
- A R Winslow
- A Ramirez
- A V Smith
- Adam Boxer
- Aimee Pierce
- Alberto Llèo
- Alberto Pilotto
- Alexa Beiser
- Alexandra Stretton
- Alexis Brice
- Allan I Levey
- Amanda G Smith
- Amanda J Myers
- Amanda Partch
- Ammar Al-Chalabi
- Amy Gerrish
- Ana Mauleón
- Andre G Uitterlinden
- Andrew B Singleton
- Andrew J Saykin
- Andrew McQuillin
- Andrew N McDavid
- Andrew P Lieberman
- André Lacour
- Angharad Morgan
- Ann C McKee
- Anna Karydas
- Anna M Toeglhofer
- Anna Maria Töglhofer
- Annick Alpérovitch
- Anthony Bayer
- Antonia Germanou
- Antonio González-Perez
- Aoibhinn Lynch
- Ashok Raj
- B Grenier-Boley
- B M Psaty
- B W Kunkle
- Badri N Vardarajan
- Barry Reisberg
- Benedetta Nacmias
- Bernadette McGuinness
- Bernardino Ghetti
- Bradley F Boeve
- Bradley T Hyman
- Brian Lawlor
- Britta Schürmann
- Bruce L Miller
- C A Ibrahim-Verbaas
- C Bellenguez
- C Berr
- C Brayne
- C Cruchaga
- C Dufouil
- C Holmes
- C M van Duijn
- C Tzourio
- C Van Broeckhoven
- Carlos Cruchaga
- Carol A Miller
- Caroline Graff
- Chang-En Yu
- Charlene Thomas
- Charles DeCarli
- Chiao-Feng Lin
- Chris S Carlson
- Christiane Reitz
- Christine Herold
- Christine M Hulette
- Christopher E Shaw
- Christopher Medway
- Chuang-Kuo Wu
- Chuanhai Cao
- Claudia Satizabal
- Clinton B Wright
- Clinton T Baldwin
- Constantine G Lyketsos
- Craig S Atwood
- Cynthia M Carlsson
- D A Bennett
- D Beekly
- D Campion
- D Evans
- D Hannequin
- D Harold
- D Rujescu
- D Zelenika
- Daniel C Marson
- Daniel H Geschwind
- Daniela Galimberti
- Daniilidou Makrina
- David C Rubinsztein
- David Craig
- David G Clark
- David H Cribbs
- David Mann
- David Wallon
- Davide Seripa
- DClin Psy
- Debby W Tsuang
- Deborah Blacker
- Deborah C Mash
- Dennis W Dickson
- Dennis W Dickson
- Despoina Avramidou
- Dmitriy Drichel
- Donald R Royall
- Donald Warden
- Douglas R Galasko
- E B Larson
- E M Reiman
- E R Martin
- Edward H Koo
- Eileen H Bigio
- Ekaterina Rogaeva
- Elaine Peskind
- Eliecer Coto
- Eliezer Masliah
- Elio Scarpini
- Elizabeth A Crocco
- Elizabeth Fisher
- Elizabeth Head
- Emma Vardy
- Eric Boerwinkle
- Erik D Roberson
- F Pasquier
- F Yesim Demirci
- Fernando Rivadeneira
- Florentino Sanchez Garcia
- Francesco Panza
- Francisco J Morón
- Frank Jessen
- Frank M LaFerla
- Frank Martiniuk
- G D Schellenberg
- G Eiriksdottir
- G Jun
- G W Beecham
- Gail P Jarvik
- Ge Li
- Gerhard Ransmayr
- Giancarlo Russo
- Gianfranco Spalletta
- Gill Livingston
- Gina Bisceglio
- Gordon Wilcock
- Gregory A Jicha
- H Hampel
- H Schmidt
- H-Erich Wichmann
- Hakon Hakonarson
- Harriet Oldham
- Harry V Vinters
- Heike Kölsch
- Helena C Chui
- Hendrik van den Bussche
- Henry L Paulson
- Hlikka Soininen
- Howard J Rosen
- Hugh Gurling
- Huntington Potter
- Ignacio Mateo
- Isabel Hernández
- Isabella Heuser
- J C Bis
- J Chung
- J D Buxbaum
- J F Powell
- J Hardy
- J I Rotter
- J Jakobsdóttir
- J L Haines
- J R Wendland
- J S K Kauwe
- J Williams
- J-C Lambert
- J-F Dartigues
- Jacques Epelbaum
- Jade Chapman
- James B Leverenz
- James D Bowen
- James J Lah
- James R Burke
- James T Becker
- James T Becker
- James Turton
- James Uphill
- Jan Bressler
- Janet A Johnston
- Jason Corneveaux
- Jason D Warren
- Jean Paul Vonsattel
- Jeffrey A Kaye
- Jennifer Williamson
- Jenny Lord
- Jens Wiltfang
- Jill R Murrell
- Joan S Reisch
- Joel H Kramer
- Johannes Kornhuber
- John C Morris
- John Collinge
- John Gallacher
- John H Growdon
- John Hardy
- John M Olichney
- John M Ringman
- John Q Trojanowski
- John R Gilbert
- John SK Kauwe
- Jonathan D Glass
- Jonathan M Schott
- Jordi Clarimon
- Josef J M Marksteiner
- Joseph E Parisi
- Joseph F Quinn
- Joshua A Sonnen
- Joshua W Miller
- Juan C Troncoso
- Julie A Schneider
- K C Wilhelmsen
- K L Hamilton-Nelson
- K L Lunetta
- K Morgan
- Karl-Heinz Jöckel
- Karolien Bettens
- Kathleen A Welsh-Bohmer
- Kelley M Faber
- Kenneth B Fallon
- Kenneth Rice
- Kevin Mayo
- Kristel Sleegers
- Kristelle Brown
- L A Farrer
- L B Cantwell
- L J Launer
- L Jones
- L Letenneur
- L Tárraga
- L-S Wang
- Lars Lannfelt
- Laura Fratiglioni
- Lawrence S Honig
- Lee-Way Jin
- Lei Yu
- Lewis H Kuller
- Li Ma
- Liana G Apostolova
- Lina Keller
- Linda J Van Eldik
- Lindy E Harrell
- Lisa L Barnes
- Lon S Schneider
- Lutz Frölich
- M A Ikram
- M A Nalls
- M A Pericak-Vance
- M Boada
- M C O'Donovan
- M Carasquillo
- M Gill
- M I Kamboh
- M L Dunstan
- M Lathrop
- M M Nöthen
- M Vronskaya
- Magda Tsolaki
- Maitee Rosende Roca
- Malcolm Dick
- Manuel Mayhaus
- Marc Delepine
- Maria Bullido
- Maria Candida Deniz Naranjo
- Maria del Zampo
- Maria Koutroumani
- Marilyn S Albert
- Mark A Sager
- Marla Gearing
- Marsel Mesulam
- Martin Dichgans
- Martin Ingelsson
- Martin R Farlow
- Martin Rossor
- Mary Sano
- Matthew J Huentelman
- Matthew P Frosch
- Matthias Riemenschneider
- Michael Hüll
- Michael J Owen
- Michael Nalls
- Michelangelo Mancuso
- Michelle Lupton
- Michjael M Barmada
- Mikko Hiltunen
- Minerva M Carrasquillo
- Montserrat Alegret
- Murray Raskind
- Myriam Fornage
- N Amin
- N C Fox
- N Denning
- N Fievet
- Natalie Ryan
- Neil W Kowall
- Neill R Graff-Radford
- Neill R Graff-Radford
- Nicholas J Bass
- Nick Warner
- Nigel J Cairns
- Nigel M Hooper
- Nilufer Ertekin-Taner
- Norman Klopp
- null null
- O Hanon
- O L Lopez
- O Valladares
- Olymbia Gkatzima
- Onofre Combarros
- Oscar L Lopez
- P Amouyel
- P De Jager
- P H St George-Hyslop
- P Holmans
- P K Crane
- P Passmore
- P Pastor
- P V Jonsson
- Panagiotis Deloukas
- Paola Bossù
- Paolo Caffara
- Pascale Barberger-Gateau
- Patrick G Kehoe
- Patrizia Mecocci
- Paul Freudenberger
- Paul Hollingworth
- Per Hoffmann
- Perrie M Adams
- Peter Dal-Bianco
- Peter J Koudstaal
- Petroula Proitsi
- Philip A Wolf
- Philip L De Jager
- R Barber
- R Clarke
- R F A G de Bruijn
- R Mayeux
- R Schmidt
- R Sims
- Rachelle S Doody
- Randall L Woltjer
- Ranjan Duara
- Regina M Carney
- Reiner Heun
- Reposo Ramírez-Lorca
- Rhian Gwilliam
- Rhoda Au
- Rita Guerreiro
- Robert A Stern
- Robert C Green
- Roger L Albin
- Roger N Rosenberg
- Ronald C Petersen
- Ronald Kim
- Ronald L Hamilton
- Rudolph E Tanzi
- Ryan M Huebinger
- S G Younkin
- S J van der Lee
- S Love
- S Mead
- S Seshadri
- S-H Choi
- Sabrina Pichler
- Salvatore Spina
- Sandra Weintraub
- Sandro Sorbi
- Sanjay Asthana
- Sara Ortega-Cubero
- Sarah Wishnek
- Shubhabrata Mukherjee
- Sid O'Bryant
- Simon Lovestone
- Steffi Riedel-Heller
- Stephen Todd
- Steven E Arnold
- Steven Ferris
- Steven L Carroll
- Steven T DeKosky
- Stuart Pickering-Brown
- Susan M McCurry
- Susanne Moebus
- T Becker
- T H Mosley
- T J Montine
- T M Foroud
- Tamara B Harris
- Thomas Benke
- Thomas D Bird
- Thomas Feulner
- Thomas G Beach
- Thomas J Fairchild
- Thomas Lumley
- Tricia A Thornton-Wells
- V Chouraki
- V Deramecourt
- V Emilsson
- V Escott-Price
- V Gudnason
- Vernon S Pankratz
- Victoria Alvarez
- Vivianna M Van Deerlin
- W A Kukull
- W Maier
- Wayne C McCormick
- Wayne W Poon
- Wei Gu
- Wendy J Mack
- William Perry
- William T Longstreth Jr
- William W Seeley
- Y Kamatani
- Yoav Ben-Shlomo
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 17/03/2015
- Field of study
This is the author accepted manuscript. The final version is available from the publisher via the DOI in this recordAPOE ε4, the most significant genetic risk factor for Alzheimer disease (AD), may mask effects of other loci. We re-analyzed genome-wide association study (GWAS) data from the International Genomics of Alzheimer's Project (IGAP) Consortium in APOE ε4+ (10 352 cases and 9207 controls) and APOE ε4- (7184 cases and 26 968 controls) subgroups as well as in the total sample testing for interaction between a single-nucleotide polymorphism (SNP) and APOE ε4 status. Suggestive associations (P<1 × 10-4) in stage 1 were evaluated in an independent sample (stage 2) containing 4203 subjects (APOE ε4+: 1250 cases and 536 controls; APOE ε4-: 718 cases and 1699 controls). Among APOE ε4- subjects, novel genome-wide significant (GWS) association was observed with 17 SNPs (all between KANSL1 and LRRC37A on chromosome 17 near MAPT) in a meta-analysis of the stage 1 and stage 2 data sets (best SNP, rs2732703, P=5·8 × 10-9). Conditional analysis revealed that rs2732703 accounted for association signals in the entire 100-kilobase region that includes MAPT. Except for previously identified AD loci showing stronger association in APOE ε4+ subjects (CR1 and CLU) or APOE ε4- subjects (MS4A6A/MS4A4A/MS4A6E), no other SNPs were significantly associated with AD in a specific APOE genotype subgroup. In addition, the finding in the stage 1 sample that AD risk is significantly influenced by the interaction of APOE with rs1595014 in TMEM106B (P=1·6 × 10-7) is noteworthy, because TMEM106B variants have previously been associated with risk of frontotemporal dementia. Expression quantitative trait locus analysis revealed that rs113986870, one of the GWS SNPs near rs2732703, is significantly associated with four KANSL1 probes that target transcription of the first translated exon and an untranslated exon in hippocampus (P≤1.3 × 10-8), frontal cortex (P≤1.3 × 10-9) and temporal cortex (P≤1.2 × 10-11). Rs113986870 is also strongly associated with a MAPT probe that targets transcription of alternatively spliced exon 3 in frontal cortex (P=9.2 × 10-6) and temporal cortex (P=2.6 × 10-6). Our APOE-stratified GWAS is the first to show GWS association for AD with SNPs in the chromosome 17q21.31 region. Replication of this finding in independent samples is needed to verify that SNPs in this region have significantly stronger effects on AD risk in persons lacking APOE ε4 compared with persons carrying this allele, and if this is found to hold, further examination of this region and studies aimed at deciphering the mechanism(s) are warranted
Up-stream events in the nuclear factor κB activation cascade in response to sparsely ionizing radiation
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2009
- Field of study
Radiation is a potentially limiting factor for manned long-term space missions. Prolonged exposure to galactic cosmic rays may
shorten the healthy life-span after return to Earth due to cancer induction. During the mission, a solar flare can be life threatening.
For better risk estimation and development of appropriate countermeasures, the study of the cellular radiation response is necessary.
Since apoptosis may be a mechanism the body uses to eliminate damaged cells, the induction by cosmic radiation of the nuclear antiapoptotic
transcription factor nuclear factor κB (NF-κB) could influence the cancer risk of astronauts exposed to cosmic radiation
by improving the survival of radiation-damaged cells. In previous studies using a screening assay for the detection of NF-κB-dependent
gene induction (HEK-pNF-κB-d2EGFP/Neo cells), the activation of this transcription factor by heavy ions was shown [Baumstark-
Khan, C., Hellweg, C.E., Arenz, A., Meier, M.M. Cellular monitoring of the nuclear factor kappa B pathway for assessment of space
environmental radiation. Radiat. Res. 164, 527–530, 2005]. Studies with NF-κB inhibitors can map functional details of the NF-κB pathway
and the influence of radiation-induced NF-κB activation on various cellular outcomes such as survival or cell cycle arrest.
In this work, the efficacy and cytotoxicity of four different NF-κB inhibitors, caffeic acid phenethyl ester (CAPE), capsaicin, the proteasome
inhibitor MG-132, and the cell permeable peptide NF-κB SN50 were analyzed using HEK-pNF-κB-d2EGFP/Neo cells. In the
recommended concentration range, only CAPE displayed considerable cytotoxicity. CAPE and capsaicin partially inhibited NF-κB activation
by the cytokine tumor necrosis factor α. MG-132 completely abolished the activation and was therefore used for experiments with
X-rays. NF-κB SN-50 could not reduce NF-κB dependent expression of the reporter destabilized Enhanced Green Fluorescent Protein
(d2EGFP). MG-132 entirely suppressed the X-ray induced NF-κB activation in HEK-pNF-κB-d2EGFP/Neo cells. In conclusion, the
degradation of the inhibitor of NF-κB (IκB) in the proteasome is essential for X-ray induced NF-κB activation, and MG-132 will be
useful in studies of the NF-κB pathway involvement in the cellular response to heavy ion exposure and other space-relevant radiation
qualities
Vorbereitung auf den Übergang von der Schule in die Arbeitswelt
- Author
- Albert Scherr
- Andreas Walther
- Arnulf Bojanowski
- Barbara Stauber
- Barbara Stauber
- Bernhard Schäfers
- Britta Reitz
- Christian Reutlinger
- Christine Resch
- Els Peters
- Erich Ribolits
- Frank Gusinde
- Franz Josef Krafeld
- Franz Josef Krafeld
- Gerd Mutz
- Günter Voß
- Heike Kahlert
- Heiner Keupp
- Heinz Reinders
- Heinz Reinders
- Heinz Reinders
- Ingo Leven
- Jutta Ecarius
- Jürgen Mansel
- Jürgen Zinnecker
- Jürgen Zinnecker
- Jürgen Zinnecker
- Klaus Hurrelmann
- Klaus Hurrelmann
- Laura Behrmann
- Lothar Böhnisch
- Lynne Chisholm
- Naomi Klein
- Nicole Dietrich
- Rainer Hubner
- Richard Münchmeier
- Richard Sennett
- Sabine Maschke
- Thomas Gericke
- Tilly Lex
- Ulrich Beck
- Uwe Sander
- Walter Hornstein
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Can Practicing Mindfulness Improve Lawyer Decision-Making, Ethics, and Leadership?
- Author
- &
- &
- &
- &
- .
- A Joseph
- A L Heifetz
- A S Norman
- Aaron Marjorie Corman
- Alexander Schlegel
- Amanda Machado
- Amiriam Elwork
- Amy Saltzman
- Andrea Naccache
- Aner Sela
- Angela Harris
- Angie Morgan
- Anna North
- Anna Ridderinkhof
- Anne Brafford
- Arden Rowell
- Barbara Fredrickson
- Barbara Fredrickson
- Barbara Fredrickson
- Betty Reddy
- Brian E Goldhagen
- Britta K H�lzel
- Cantrell
- Center For Mindfulness In
- Clair Brown
- Clair Brown
- Colo
- Colo
- Dan Kahan
- David Brendel
- David M Zlotnick
- Deane H See Generally
- Deborah Cantrell
- Deborah J Cantrell
- Deborah L Rhode
- Deborah L Rhode
- Deborah Rhode
- Debra S See Generally
- Derek Bok
- Donald J Polden
- Drucker Sch
- E F Schumacher
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E G See
- E Ronald
- E Sanford
- Edward K See Generally
- Elena Lytkina Botelho
- Elisha Goldstein
- Emily Holland
- Emily K Lindsay
- Eric L See Generally
- Eyal Rosenstreich
- Fadel Zeidan
- Farb
- Felder
- Francesco Pagnini
- Fred B See Generally
- G Richard
- George Siedel
- Gerd Gigerenzer
- H Deane
- H Id
- H Peter
- H Peter
- H Peter
- H Peter
- Hafenbrack
- Hafenbrack
- Hamilton
- Howard B Beckman
- Howard See
- Huang
- Huang
- Huang
- Id
- Id
- Id
- Id
- Id
- Id
- Id
- Id
- Id
- Id
- Id
- Id
- Id
- Id
- J
- J Nick Badgerow
- James Podgers
- Jennifer L Aaker
- Jennifer Mueller
- Jennifer Mueller
- Jennifer Mueller
- Jennifer S
- Jeremy Hunter &
- Jerome M Organ
- Jo Ann Heydenfeldt
- Johan M�rtensson
- Johannes Grapendorf
- Jonathan Vehar
- Jr Shapiro
- Judson A Brewer
- Judson A Brewer
- Judson Brewer
- Katerina P Lewinbuk
- Katrina June Lee
- Katrina Schwartz
- Kenneth J Arrow
- Kenneth J Arrow
- L J St
- Laura Huang
- Leo Katz
- Leonard L Riskin
- Linda E Carlson
- Lisa J Merlo
- Luke Fortney
- M
- M Brent
- Madhav Goyal
- Maeda Riaz
- Maria Gonzalez
- Mark Williams &
- Mary Brophy
- Mary Catherine Beach
- Matthew Flickstein
- Megan Reitz
- Mercer L
- Michael Chaskalson
- Michael Wheeler
- Michelle Obama
- Miguel Farias &
- Mindful
- Mindful
- Model
- Mueller
- Nathalie Martin
- Negotiating Shirli Kopelman
- Nicholas Barnes
- Owen D Jones
- Pat Croskerry
- Patricia L Dobkin
- Patrick R Krill
- Paul Brest &
- Peter H. Huang
- Phillip Moffitt
- Phillip See
- Psychol Behav
- Purser &
- Rafael A Calvo &
- Rafal Marciniak
- Reitz
- Reitz
- Richard C See Generally
- Riskin
- Riskin
- Robert Rosenbaum
- Robert Wright
- Roger Fisher &
- Rosenbaum
- Russell Golman
- Ruth Whippman
- Sally Satel
- See David Gelles
- See Generally
- See Jerker Denrell
- See Teresa Kissane Brostoff
- Shapiro
- Shauna L Shapiro
- Sheila N Garland
- Sturm Coll
- Supra Mertz
- Supra Mueller
- Thalia Gonzalez
- The
- The Ceo Genome Website
- Tim Kasser
- Todd B Kashdan
- Tor Neuroscience Lab
- Transforming Steven Keeva
- U Ark Rock L
- W Ben
- Walden
- What&apos
- William P See Generally
- Yi-Yuan Tang &
- Yoshio Nakamura
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2017
- Field of study
Future avenues for Alzheimer's disease detection and therapy: liquid biopsy, intracellular signaling modulation, systems pharmacology drug discovery
- Author
- A. Claudio Cuello
- Abate
- Aguilar
- Aisen
- Alejandro Lucía
- Alexandrov
- Alzforum
- Anand
- Andrea Vergallo
- Andreasson
- Andrieu
- Anstey
- Arnsten
- Aso
- Bacioglu
- Baldacci
- Baldacci
- Baldacci
- Baldacci
- Baldacci
- Barnes
- Barro
- Bartels
- Bartsch
- Bassett
- Bero
- Bettcher
- Blokland
- Bode
- Boettner
- Britta Hänisch
- Brosseron
- Brown
- Bruhn
- Bruno Vellas
- Brureau
- Byers
- Cao
- Caraci
- Cavedo
- Cha
- Chiesa
- Chiesa
- Christ
- Cirrito
- Citron
- Corbett
- Cotman
- Cuello
- Cummings
- Cummings
- Cummings
- Dage
- Deng
- Dickerson
- Diniz
- Dragicevic
- Drange
- Dubois
- Dubois
- Dubois
- Dubois
- Edison
- Eikelenboom
- Enzo Emanuele
- European Medicines Agency
- Ezio Giacobini
- Fan
- Farlow
- Fehér
- Ferretti
- Fiandaca
- Filippo Baldacci
- Filippo Caraci
- Fisher
- Forlenza
- Fossati
- Francisco Llavero
- Franzmeier
- Freret
- Gaetani
- Gates
- Geerts
- Geerts
- Geerts
- Giacobini
- Giacobini
- Giacobini
- Giacobini
- Glahn
- Goetzl
- Goetzl
- Goetzl
- Goetzl
- Grieco
- Guzman-Martinez
- Hammond
- Hampel
- Hampel
- Hampel
- Hampel
- Hampel
- Hampel
- Hampel
- Hampel
- Hampel
- Hampel
- Hampel
- Hanzel
- Hao
- Hara
- Harald Hampel
- Haroutunian
- Harrold
- Hatanpää
- Hayashi
- Hill
- Hillman
- Holmquist
- Hooper
- Horrocks
- Hospital
- Huesa
- Hung
- Hölscher
- Iulita
- Iulita
- Jack
- Jack
- Jaffe
- Janelidze
- Janelidze
- Jelic
- Jojo
- Jorgensen
- José L. Zugaza
- Kang
- Karl Broich
- Karran
- Kelly Virecoulon Giudici
- Kern
- Kou
- Kozakov
- Kuhle
- Kumar
- Lagorce
- Lahiri
- Laurent
- Layé
- Lista
- Lopera
- Macalino
- Mahringer
- Maillet
- Mandolesi
- Manterola
- Marion Haberkamp
- Marrazzo
- Mattsson
- Mattsson
- Mattsson
- Maurice
- McGeer
- McKhann
- Medland
- Melah
- Mielke
- Mielke
- Miller
- Minthon
- Mitsopoulos
- Mizuarai
- Mohs
- Molinuevo
- Moreno-Gonzalez
- Morgan
- Mori
- Mori
- Morisaki
- Morris
- Mustapic
- Nabers
- Nakamura
- Nct02244541
- Nct02756858
- Ngandu
- Nikolic
- Nilsberth
- Nitsch
- Nordengen
- O'Bryant
- Olsson
- Ovod
- Pablo Lemercier
- Pakaski
- Palmqvist
- Palop
- Palop
- Parbo
- Park
- Parri
- Perez-Nievas
- Petzold
- Popp
- Preische
- Prickaerts
- Putcha
- Rainer
- Rask-Andersen
- Reiman
- Reitz
- Ribe
- Richiardi
- Robert
- Robert Nisticò
- Rocco
- Rodriguez-Vieitez
- Rogers
- Rogers
- Rogers
- Roukos
- Saito
- Scarmeas
- Schlaepfer
- Schwarz
- Seeley
- Seino
- Selkoe
- Sheline
- Shine
- Simone Lista
- Skillback
- Snapper
- Solarski
- Stepanov
- Sutphen
- Szczechowiak
- Sánchez-Valle
- Sørensen
- Tang
- Teipel
- Teunissen
- Thorsell
- Torrisi
- Toschi
- Trojanowski
- van Assema
- van Charante
- Vandame
- Vassalle
- Vauzour
- Vauzour
- Vega
- Vergallo
- Vergallo
- Vergallo
- Wallin
- Wallin
- Wallin
- Wallin
- Walsh
- Wang
- Wattmo
- Wattmo
- Wattmo
- Westlye
- Weston
- Weston
- Wilson
- Winblad
- Winblad
- Wu
- Yan
- Yang
- Zetterberg
- Zetterberg
- Zhang
- Zhao
- Zhao
- Zhao
- Zhao
- Zheng
- Öhrfelt
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
New insights into the genetic etiology of Alzheimer’s disease and related dementias
- Author
- Aaltonen Lauri
- Aaltonen Vesa
- Aarsland Dag
- Aavikko Mervi
- Abalos Mariana Sanchez
- Abdelnour Carla
- Abner Erin
- Abraham Richard
- Adams Hieab
- Adams Perrie M.
- Adarmes-Gómez Ad
- Adarmes-Gómez Astrid D.
- Aguilera Nuria
- Aguilera Nuria
- Aguirre Alyssa
- Ahmad Shahzad
- Akinyemi Rufus O.
- Al-Chalabi Ammar
- Alarcón-Martín Emilio
- Albert Marilyn S.
- Albin Roger L.
- Alcolea Daniel
- Alegret Montserrat
- Ali Muhammad
- Allen Mariet
- Allende Irene Rosas
- Alonso María Dolores
- Alonso María Dolores
- Alvarez Ignacio
- Alvarez Lisa
- Amer-Ferrer Guillermo
- Amin Najaf
- Amouyel Philippe
- Anastasiou Anna
- Anastasiou Costas
- Andrade Victor
- Andreassen Ole A.
- Andreoni Simona
- Antequera Martirio
- Antikainen Riitta
- Antonell Anna
- Anttonen Vuokko
- Antúnez Carmen
- Aparicio Hugo J.
- Apostolova Liana G.
- Appollonio Ildebrando
- Arcaro Marina
- Archetti Silvana
- Armstrong Nicola
- Armstrong Nicola J.
- Arnold Steven E.
- Arosio Beatrice
- Arvas Mikko
- Assogna Francesca
- Asthana Sanjay
- Athanasiu Lavinia
- Atwood Craig S.
- Auge Franck
- Auranen Annika
- Auvinen Päivi
- Awaisa Ghazal
- Ayres Gayle
- Bacha Juan Ignacio
- Bahadori Maryam
- Bahrami Shahram
- Bailly Henri
- Baldwin Clinton T.
- Banaj Nerisa
- Baquero Miquel
- Barber Robert C.
- Barnes Lisa L.
- Barral Sandra
- Barral Sandra
- Bass Nicholas J.
- Bass Nick
- Bastiani Patrizia
- Bayer Anthony
- Beach Thomas G.
- Becker James T.
- Becker James T.
- Becker Tim
- Beecham Gary W.
- Beekly Duane
- Behrens Tim
- Beiser Alexa
- Belezhanska Diyana
- Bellenguez Céline
- Below Jennifer E.
- Below Jennifer E.
- Ben-Shlomo Yoav
- Benchek Penelope
- Benchek Penelope
- Benitez Bruno A.
- Bennett David
- Benussi Alberto
- Benussi Luisa
- Bergh Sverre
- Bernardo-Harrington Mateus
- Berr Claudine
- Bertelson John
- Besse Céline
- Bessi Valentina
- Betts Jo
- Bhangale Tushar
- Biessels Geert Jan
- Binetti Giuliano
- Bing Nan
- Bird Thomas D.
- Bis Joshua C.
- Biswas Shameek
- Bizarro Alessandra
- Bjerke Maria
- Blacker Deborah
- Blesa Rafael
- Blomster Timo
- Boada Mercè
- Boecker Henning
- Boerwinkle Eric
- Boeve Bradley F.
- Boland Anne
- Borroni Barbara
- Boschi Silvia
- Bosnes Ingunn
- Bossù Paola
- Bowen James D.
- Bowers Natalie
- Boxer Adam
- Brauer Matt
- Brayne Carol
- Brein Georg
- Bresner Catherine
- Bressler Jan
- Breteler Monique
- Brewer James
- Brice Alexis
- Brodaty Henry
- Broeckhoven Christine Van
- Bronson Paola
- Brookes KJ
- Brown Kristelle
- Brown Kristelle S.
- Brusco Luis Ignacio
- Bråthen Geir
- Buendia Mar
- Buiza-Rueda Dolores
- Bullido María J.
- Burguera Juan Andrés
- Burholt Vanessa
- Burke James R.
- Burns Jeffrey M.
- Bush Will S.
- Bush William S.
- Buxbaum Joseph D.
- Bûrger Katharina
- Cairns Nigel J.
- Calero Miguel
- Caliskan Minal
- Call Katherine
- Call Kathy
- campion Dominique
- Campos-Martin Rafael
- Cano Amanda
- Cantwell Laura B.
- Cao Chuanhai
- Carlson Christopher S.
- Carlsson Cynthia M.
- Carney Regina M.
- Carpén Olli
- Carracedo Ángel
- Carrasquillo Minerva M.
- Carrillo F.
- Carrillo Fátima
- Carrion-Claro M.
- Carrión-Claro Mario
- Casajeros María José
- Castaño Eduardo M.
- Cañabate Pilar
- Cañabate Pilar
- Cecchetti Roberta
- Cervera-Carles Laura
- Challis Ben
- Chang Diana
- Chapuis Julien
- Charbonnier Camille
- Chasman Daniel
- Chasse Scott
- Chatelain Clement
- Chauhan Ganesh
- Chen Chia-Yen
- Chen Hao
- Chen Hubert
- Chen Hung-Hsin
- Chen Xing
- Chene Geneviève
- Chesi Alessandra
- Chesselet Marie-Francoise
- Chhibber Aparna
- Chillotti Caterina
- Chin Nathaniel A.
- Chipi Elena
- Choy David
- Chu Audrey
- Chui Helena C.
- Chung Jaeyoon
- Chung Jaeyoon
- Ciccone Simona
- Ciullo Valentina
- Claassen Jurgen A. H. R.
- Clarimon Jordi
- Clark Christopher
- Clarke Robert
- Close David
- Collinge John
- Comic Hata
- Conti Elisa
- Cores Valeria
- Corma-Gómez Anaïs
- Costa Marcos R.
- Costantini Emanuele
- Cox Simon
- Craft Suzanne
- Craig David
- Crane Paul K.
- Cribbs David H.
- Crocco Elizabeth A.
- Crohns Marika
- Cruchaga Carlos
- Cuccaro Michael L.
- Cuccaro Michael L.
- Cuesta Carolina
- Cullum Munro
- Cummings Beryl
- Cupples Adrienne L.
- Custodero Carlo
- Daian Delphine
- Dalmasso Maria Carolina
- Daly Mark
- Damotte Vincent
- Daniele Antonio
- Darby Eveleen
- Dardiotis Efthimios
- Dartigues Jean-François
- Davies Chloe
- Davies Gail
- Davis Barbara
- Davis Justin Wade
- de Deyn Peter Paul
- De Jager Philip L.
- de Mendonça Alexandre
- de Munain Adolfo Lopez
- de Paiva Lopes Katia
- de Rojas Itziar
- de Witte Lot D.
- Debette Stéphanie
- DeCarli Charles
- DeCarli Charles S.
- Deckert Jürgen
- del Ser Teodoro
- Deleuze Jean-François
- della Briotta Parola Pietro
- della Briotta Parolo Pietro
- Deloukas Panagiotis
- Deloukas Pangiotis
- Denning Nicola
- Deramecourt Vincent
- Deramerourt Vincent
- DeStefano Anita
- DeToledo John
- Dichgans Martin
- Dick Malcolm
- Dickson Dennis W.
- Diego Susana
- Diehl-Schmid Janine
- Diez-Fairen Mónica
- Diogo Dorothee
- Djurovic Srdjan
- Dombroski Beth A.
- Dongen Jasper Van
- Donner Kati
- Doody Rachelle S.
- Dowzell Kimberley
- Drichel Dmitriy
- Duara Ranjan
- Dubois Bruno
- Dufouil Carole
- Duperron Marie-Gabrielle
- Dupuis Josée
- Duron Emmanuelle
- Düzel Emrah
- Eaton Susan
- Ehm Meg
- Eicher John
- Eiriksdottir Gudny
- Eklund Kari
- Elenius Klaus
- Elliott Amanda
- Engelborghs Sebastiaan
- Epelbaum Jacques
- Ertekin-Taner Nilüfer
- Escott-Price Valentina
- Escuela R.
- Escuela Rocío
- Esmaeeli Sahar
- Espinosa Ana
- Espinosa Miguel Angel Labrador
- Etchepareborda Ignacio
- Evans Denis A.
- Evans Tavia
- Ewers Michael
- Faber Kelley M.
- Fabrizio Tagliavini
- Fairchild Thomas J.
- Fallon Kenneth B.
- Fan Frank
- Fardo David W.
- Farlow Martin R.
- Farotti Lucia
- Farrell John J.
- Farrer Lindsay A.
- Fenoglio Chiara
- Fernandez-Hernandez Victoria
- Fernández-Fuertes Marta
- Ferrarese Carlo
- Ferrari Raffaele
- Ferreira Catarina B.
- Ferri Evelyn
- Ferris Steven
- Feulner Thomas
- Fievet Nathalie
- Fin Bertrand
- Fischer Peter
- Fisher Elizabeth
- Fitzpatrick Annette
- Fladby Tormod
- Fließbach Klaus
- Fohner Alison E.
- Fongang Bernard
- Fornage Myriam
- Foroud Tatiana M.
- Forsell Charlotte
- Fortea Juan
- Fostinelli Silvia
- Fox Caroline
- Fox Nick
- Fox Nick C.
- Franco-Macías Emlio
- Frank-García Ana
- Frikke-Schmidt Ruth
- Froelich Lutz
- Frosch Matthew P.
- Frölich Lutz
- Fulton-Howard Brian
- Fulton-Howard Brian
- Färkkilä Martti
- Gailhajenet Anna
- Galasko Douglas R.
- Galeano Pablo
- Galimberti Daniela
- Gamboa Adriana
- Ganguli Mary
- Ganna Andrea
- Garcia-Gonzalez Pablo
- Garcia-Madrona Sebastian
- Garcia-Ribas Guillermo
- Garcia-Tabuenca Javier
- García-Alberca Jose Maria
- García-González Pablo
- Garrote-Espina L.
- Garrote-Espina Lorena
- Gearing Marla
- Geerlings Mirjam
- Georgantas Bob
- George-Hyslop Peter St
- Germani Sandra
- Gerrish Amy
- Geschwind Daniel H.
- Ghanbari Mohsen
- Ghetti Bernardino
- Ghidoni Roberta
- Ghosh Soumitra
- Giedraitis Vilmantas
- Giegling Ina
- Gilbert John R.
- Gill Michael
- Giorgio Giaccone
- Glatt Stephen J.
- Goate Alison M.
- Goldhardt Oliver
- Gomez-Fonseca Duber
- Gonzalez Hector M.
- González-Pérez Antonio
- Gordillo Jorge Esparza
- Gormley Padhraig
- Goss Monica
- Gossel Matthias
- Grabe Hans
- Grabowski Thomas J.
- Gracia-Tabuenca Javier
- Graff Caroline
- Graff-Radford Neill R.
- Graham Robert
- Grand Quentin Le
- Grande Giulia
- Grant Struan F. A.
- Green Emma
- Green Robert C.
- Greenberg Steven
- Grenier-Boley Benjamin
- Grimmer Timo
- Growdon John H.
- Grunin Michelle
- Grünblatt Edna
- Gu Wei
- Gudnason Vilmundur
- Guerreiro Rita
- Guetta-Baranes Tamar
- Guitart Marina
- Gurling Hugh
- Gursoy Ulvi
- Gwilliam Rhian
- Gómez-Garre P.
- Gómez-Garre Pilar
- Haapasalo Annakaisa
- Habes Mohamad
- Hadjigeorgiou Georgios
- Haines Jonathan L.
- Haines Jonathan L.
- Hakonarson Hakon
- Hall James
- Hamilton Ronald L.
- Hamilton-Nelson Kara L.
- Hampel Harald
- Hannequin Didier
- Hannula-Jouppi Katariina
- Hanon Olivier
- Harari Oscar
- Hardy John
- Harju Jarmo
- Harju Terttu
- Harold Denise
- Harrell Lindy E.
- Hartmann Annette M.
- Harvima Ilkka
- Harwood Janet
- Hausner Lucrezia
- Haut Jacob
- Hautala Nina
- Havulinna Aki
- Head Elizabeth
- Heap Graham
- Heckbert Susan R.
- Hedman Åsa
- Heikkinen Sami
- Heilmann-Heimbach Stefanie
- Helisalmi Seppo
- Henderson Victor W.
- Hendolin Minna
- Heneka Michael T.
- Hernandez Michelle
- Hernández Isabel
- Herold Christine
- Heron Samuel
- Herrmann Martin J.
- Heun Reinhard
- Heuser Isabella
- Hevilla Saray
- Heyne Henrike
- Hiekkalinna Tero
- Hiltunen Mikko
- Hinttala Reetta
- Hochfeld Marla
- Hodges Angela
- Hofer Edith
- Hoffman Joshua
- Hoffmann Per
- Hohman Timothy
- Hollingworth Paul
- Holmans Peter A.
- Holmes Clive
- Holstege Henne
- Holzinger Emily
- Hong Elliot
- Honig Lawrence S.
- Hooper Nigel M.
- Hort Jakub
- Hu Xinli
- Huang Yunfeng
- Huebinger Ryan M.
- Huentelman Matthew J.
- Hughes Timothy
- Huhtakangas Johanna
- Huilaja Laura
- Hulette Christine M.
- Hulsman Marc
- Humphrey Jack
- Hunkapiller Julie
- Hyman Bradley T.
- Hynan Linda S.
- Hyvärinen Kati
- Hüll Michael
- Ibanez Laura
- Ibarria Marta
- Ikram M. Arfan
- Ingelsson Martin
- Ingino Carlos
- Iriarte Maite Mendioroz
- Isomäki Pia
- Jacob Howard
- Jalanko Anu
- Jambulingam Dhanaprakash
- Janowitz Daniel
- Jansen Iris E.
- Jarvik Gail P.
- Jayadev Suman
- Jessen Frank
- Jesús S.
- Jesús Silvia
- Jian Xueqiu
- Jiménez Manuel González
- Jin Lee-Way
- Joensuu Heikki
- Johansson Charlotte
- John Sally
- Johnson Kim
- Johnson Leigh
- Johnston Janet A.
- Johnston Jarret A.
- Jones Lesley
- Juan Pascual Sánchez
- Julkunen Valtteri
- Jun Gyungah R.
- Junttila Juhani
- Juonala Markus
- Jussila Airi
- Järvensivu Elina
- Jöckel Karl-Heinz
- Kaarniranta Kai
- Kaarteenaho Riitta
- Kaiharju Essi
- Kaipiainen-Seppänen Oili
- Kajanne Risto
- Kalaoja Marita
- Kalpala Kirsi
- Kamboh M. Ilyas
- Kanai Masahiro
- Kangasniemi Eeva
- Kankaanranta Hannu
- Kaprio Jaakko
- Karihtala Peeter
- Karjalainen Juha
- Karjalainen Minna
- Karlsson Antti
- Karydas Anna M.
- Kastumata Yuriko
- Katz Mindy J.
- Kaunisto Mari
- Kauppi Paula
- Kauppila Saila
- Kautz Tiffany F.
- Kauwe John
- Kaye Jeffrey A.
- Keene C. Dirk
- Kehoe Patrick G.
- Kerchner Geoff
- Kettunen Johannes
- Khaleeq Aisha
- Kiiskinen Tuomo
- Kilander Lena
- Kilpeläinen Elina
- Kilpi Terhi
- Kim Ronald
- King Karen S.
- Kiviniemi Mikko
- Kivipelto Miia
- Kleineidam Luca
- Klinger Kathy
- Klopp Norman
- Knebl Janice
- Knol Maria
- Kochen Silvia
- Kohler Eduardo
- Kohler Matias
- Koivisto Anne
- Kornhuber Johannes
- Koskinen Miika
- Kosma Veli-Matti
- Kosmidis Mary H.
- Koulu Leena
- Kowall Neil W.
- Kramer Joel H.
- Kremen William
- Kristiansson Kati
- Kujala Urho
- Kuksa Pavel P.
- Kuksa Pavel P.
- Kukull Walter A.
- Kulkarni Diptee
- Kunkle Brian W.
- Kurki Mitja
- Kuulasmaa Teemu
- Kuzma Amanda B.
- Kvikstad Erika
- Kähönen Mika
- Kälviäinen Reetta
- Kölsch Heike
- Küçükali Fahri
- Laakkonen Eija
- Laakso Markku
- Laatikainen Tiina
- Labrador Ma
- Lacaze Paul
- Lacidogna Giordano
- Lacour André
- Laczo Jan
- LaFerla Frank M.
- Lafuente Asunción
- Lage Carmen
- Lage Carmen
- Lah James J.
- Lahdenperä Sanni
- Lahti Jari
- Laiho Päivi
- Laitinen Tarja
- Laivuori Hannele
- Lambert Jean-Charles
- Larson Eric B.
- Laske Christoph
- Laukka Erika J.
- Laukkanen Jari
- Laukkanen Markku
- Launer Lenore
- Lauria Alessandra
- Lawlor Brian
- Lee Chien-Yueh
- Lee Chien-Yueh
- Lee Edward B.
- Lee Jiwoo
- Legaz Agustina
- Lehisto Arto
- Lehistö Arto
- Lehtisalo Jenni
- Lehtonen Anne
- Lehtonen Heli
- Lemmelä Susanna
- Lerch Ondrej
- Lerner Alan
- Lertratanakul Apinya
- Leung Yuk Yee
- Leverenz James B.
- Levey Allan I.
- Li Mingyao
- Li Shuo
- Lieberman Andrew P.
- Linden Kari
- Lindström Jaana
- Lipton Richard B.
- Lisso Julieta
- Litkowski Elizabeth
- Liu Dan
- Liu Dongyu
- Liu Jimmy
- Liu Xuan
- Livingston Gill
- Lleó Alberto
- Llorens Vincent
- Loboda Andrey
- Loerch Patrick
- Logue Mark
- Loitfelder Marisa
- Longstreth William
- Loomis Stephanie
- Lopez Oscar
- Lord Jenny
- Loukola Anu
- Love Seth
- Lovestone Simon
- Lu Tim
- Luckcuck Lauren
- Lunetta Kathryn L.
- Luodonpää Marja
- Lupton Michelle
- Lyketsos Constantine G.
- Lynch Aoibhinn
- Lähteenmäki Sini
- López-García Sara
- López-García Sara
- Löwemark Malin
- Ma Yiyi
- Macias Juan
- Macias-García D.
- Macias-García Daniel
- MacLeod Catherine A.
- Macías Juan
- Maier Wolfgang
- Maillard Pauline
- Mains Douglas
- Malamon John
- Malarstig Anders
- Malik Rainer
- Mangialasche Francesca
- Mangone Carlos
- Mann David
- Mannermaa Arto
- Manning Alisa
- Mantere Tuomo
- Manzanares Salvadora
- Maranville Joseph
- Margaret Flanagan E.
- Marioni Riccardo
- Maroñas Olalla
- Marquié Marta
- Mars Nina
- Marshall Catherine
- Marshall Rachel
- Marson Daniel C.
- Martin Eden R.
- Martinez de Pancorbo Marian
- Martiniuk Frank
- Martín Elvira
- Martínez Begoña
- Martínez Victoriana
- Martínez-Lage Álvarez Pablo
- Martínez-Larrad María Teresa
- Marín M.
- Marín Marta
- Marín Tamara
- Marín-Muñoz Juan
- Mash Deborah C.
- Masliah Eliezer
- Massman Paul
- Masullo Carlo
- Masurkar Arjun
- Matakidou Athena
- Mather Karen
- Matoska Vaclav
- Mattson Johanna
- Mattsson Hannele
- Mauleón Ana
- Mayeux Richard
- Mayhaus Manuel
- Mazoyer Bernard
- McCarthy Linda
- McCarthy Mark
- McCormick Wayne C.
- McCurry Susan M.
- McDavid Andrew N.
- McDonough Stefan
- McDonough Stefan
- McGuinness Bernadette
- McKee Ann C.
- McQuillin Andrew
- Mead Simon
- Mecocci Patrizia
- Medel Nancy
- Medina Miguel
- Meggy Alun
- Mehrabian Shima
- Mehta Vinay
- Mei Hao
- Mendoza Silvia
- Menéndez-González Manuel
- Meretoja Tuomo
- Merlín Isabel Sastre
- Mesulam Marsel
- Metsärinne Kaj
- Mez Jesse
- Michon John
- Mihova Kalina Yonkova
- Miller Bruce L.
- Miller Carol A.
- Miller Joshua W.
- Miller Melissa
- Mir Pablo
- Mishra Aniket
- Moebus Susanne
- Mohammed Elhaj
- Mol Merel
- Molina-Porcel Laura
- Montes Angel Martín
- Montine Thomas J.
- Montrreal Laura
- Monuki Edwin S.
- Morales Atahualpa Castillo
- Morelli Laura
- Moreno Fermin
- Moreno Mariona
- Moreno-Grau Sonia
- Morgan Kevin
- Morris John C.
- Mosley Thomas
- Muchnik Carolina
- Mukherjee Shubhabrata
- Mummery Catherine
- Muslin Anthony
- Myers Amanda J.
- Mäkelä Johanna
- Mäkelä Tomi
- Männikkö Lotta
- Mäntylä Päivi
- Nacmias Benedetta
- Naj Adam C.
- Nash William
- Natunen Teemu
- Ngandu Tiia
- Nguyen Trung
- Nicolas Gael
- Nielsen Sune Fallgaard
- Niemi Mari E.
- Nieminen Pekka
- Niiranen Teemu
- Nordestgaard Børge G.
- Novack Gisela
- Nuñez-Llaves Raúl
- Nyquist Paul
- Nöthen Markus M.
- Oh Danny
- Olaso Robert
- Olichney John M.
- Olivar Natividad
- Olivé Clàudia
- Ollila Terhi
- Orellana Adelina
- Orsini Michela
- Ortega Gemma
- Ortiz Cecilia
- Ory Marcia
- Owen Michael
- Owen Michael J.
- O’Bryant Sid
- O’Connell Jeffrey
- O’Donovan Michael
- O’Donovan Michael C.
- Paajanen Teemu
- Padovani Alessandro
- Pakkanen Raimo
- Palacio Dana Lis
- Palin Kimmo
- Palmer Raymond
- Palomäki Antti
- Palotie Aarno
- Palotie Ulla
- Palta Priit
- Pancho Ana
- Paolo Caffarra
- Papenberg Goran
- Parisi Joseph E.
- Parkkinen Jaakko
- Parnetti Lucilla
- Partanen Jukka
- Parveen Kayenat
- Pasquier Florence
- Passmore Peter
- Passmore Peter
- Pastor Alfonso Arias
- Pastor Ana Belén
- Pastor Pau
- Patel Yash
- Patel Yogen
- Paulson Henry L.
- Paus Tomas
- Pausova Zdenka
- Pavlik Valory
- Paydarfar David
- Pelejà Esther
- Pelejá Ester
- Pelkonen Margit
- Peloso Gina
- Peltola Jukka
- Peltonen Markku
- Peltonen Sirkku
- Pendergrass Sarah
- Perez Victoria
- Pericak-Vance Margaret A.
- Pericard Pierre
- Periñán Mt
- Periñán-Tocino María Teresa
- Perneczky Robert
- Perola Markus
- Peskind Elaine
- Peters Oliver
- Petersen Ronald C.
- Peterson Andrew
- Petrovski Slavé
- Phillips-Cremins Jennifer E.
- Pickering-Brown Stuart
- Pierce Aimee
- Pihlajamäki Jussi
- Pijnenburg Yolande A. L.
- Pikkarainen Sampsa
- Pinchler Sabrina
- Pineda Juan A.
- Pineda-Sánchez R.
- Pineda-Sánchez Rocío
- Piras Fabrizio
- Piras Federica
- Pirilä Laura
- Pisanu Claudia
- Pitkäranta Anne
- Piñol-Ripoll Gerard
- Plenge Robert
- Podgornaia Anna
- Polak Thomas
- Politis Daniel G.
- Polk Marsha
- Poon Wayne W.
- Popovic Relja
- Popp Julius
- Posthuma Danielle
- Potter Huntington
- Powell John
- Powell John F.
- Preckler Silvia
- Prestia Federico Ariel
- Priller Josef
- Proitsi Petra
- Prokic Ivana
- Psaty Bruce M.
- Puerta Raquel
- Pulford David
- Pulkki Kari
- Pussinen Pirkko
- Pylkäs Katri
- Pärn Kalle
- Pérez-Cordón Alba
- Pérez-Tur Jordi
- Qu Liming
- Quarless Danjuma
- Quenez Olivier
- Quiceno Mary
- Quinn Joseph F.
- Quintela Inés
- Rahimov Fedik
- Raikkonen-Talvitie Katri
- Rainero Innocenzo
- Raj Ashok
- Raj Towfique
- Rajabli Farid
- Rajpal Deepak
- Rajula Reddy
- Ramakers Inez
- Ramirez Alfredo
- Raskind Murray
- Rathinakannan Venkat Subramaniam
- Real de Asúa Diego
- Real Luis M.
- Reeve Mary Pat
- Reiman Eric M.
- Reinders Marcel J. T.
- Reisberg Barry
- Reisch Joan S.
- Reitz Christiane
- Remes Anne
- Reyes-Dumeyer Dolly
- Riaz Moeen
- Rice David
- Rich Stephen
- Ridge Perry
- Riedel-Heller Steffi
- Riederer Peter
- Riemenschneider Matthias
- Riley-Gillis Bridget
- Ringman John M.
- Rinne Juha
- Rios Mario
- Ripatti Samuli
- Ritari Jarmo
- Rivas Manuel
- Roberson Erik D.
- Roberto Natalia
- Rodrigo Silvia
- Rodrigo-Herrero Silvia
- Rodriguear Monica
- Rodriguez-Rodriguez Eloy
- Rodríguez Carmen Martínez
- Roeck Ellen De
- Rogaeva Ekaterina
- Rojo Matias
- Romero Jose
- Rongve Arvid
- Rosen Howard J.
- Rosenberg Roger N.
- Rosende-Roca Maitée
- Roshchupkin Gena
- Rossi Giacomina
- Rossi Paolo Dionigi
- Rossor Martin
- Rossor Martin
- Rotter Jerome
- Roveta Fausto
- Royall Donald R.
- Royo Jose Luis
- Rubino Elisa
- Rubinsztein David C.
- Ruiz Agustín
- Rujescu Dan
- Runz Heiko
- Ryan Natalie S.
- Ryan Nathalie
- Rábano Alberto
- Rüeger Sina
- Saba Yasaman
- Sachdev Perminder
- Saenz Aldo
- Sager Mark A.
- Sakka Paraskevi
- Sala Gessica
- Salmi Teea
- Salminen Aino
- Salo Tuula
- Salomaa Veikko
- Saltvedt Ingvild
- Salvadori Nicola
- Sanabria Ángela
- Sanchez-Garcia Florentino
- Sando Sigrid B.
- Sano Mary
- Sargurupremraj Murali
- Sarnowski Chloé
- Sastre Isabel
- Satizabal Claudia L.
- Saykin Andrew J.
- Scamosci Michela
- Scarmeas Nikolaos
- Scarpini Elio
- Schellenberg Gerard D.
- Scheltens Philip
- Scherbaum Norbert
- Scherer Martin
- Schleutker Johanna
- Schmid Matthias
- Schmidt Helena
- Schmidt Reinhold
- Schneider Anja
- Schneider Julie A.
- Schneider Lon S.
- Schott Jonathan M.
- Schutzman Jennifer
- Schürmann Britta
- Seeley William W.
- Seitsonen Sanna
- Sekhar Hema
- Selbæk Geir
- Selnes Per
- Seripa Davide
- Serpente Maria
- Serpi Raisa
- Serrano Manuel
- Seshadri Sudha
- Sevillano Zulma
- Sha Jin
- Shadrin Alexey A.
- Shaikho Elmutaz
- Shaw Christopher E.
- Shcherban Anastasia
- Shin Jean
- Shofany Jacob
- Shulman Joshua M.
- Siirtola Harri
- Simino Jeannette
- Sims Rebecca
- Sinisalo Juha
- Sipeky Csilla
- Sipilä Kirsi
- Sipilä Timo P.
- Siponen Maria
- Sistonen Tuuli
- Skrobot Olivia
- Sleegers Kristel
- Slifer Susan
- Slifer Susan H.
- Sliz Eeva
- Small Scott
- Smaoui Nizar
- Smith A. David
- Smith Amanda G.
- Smith Janet P.
- Smith Jennifer
- Snijders Gijsje J. L.
- Soininen Hilkka
- Solfrizzi Vincenzo
- Solis Patricia
- Solomon Alina
- Song Yeunjoo
- Song Yeunjoo E.
- Sonnen Joshua A.
- Sorbi Sandro
- Sotolongo-Grau Oscar
- Spallazzi Marco
- Spalletta Gianfranco
- Spina Salvatore
- Spottke Annika
- Squassina Alessio
- Stern Robert A.
- Stevens Alan B.
- Stordal Eystein
- Strandberg Timo
- Strauss Erich
- Strittmatter Stephen M.
- Ståhlbom Anne Kinhult
- Sultzer David
- Suominen Liisa
- Sussams Rebecca
- Swerdlow Russell H.
- Sáez María Eugenia
- Sánchez-Arjona María Bernal
- Sánchez-Valle Raquel
- Takalo Mari
- Tanzi Rudolph E.
- Tartan Juan Pablo
- Tasanen Kaisa
- Taskinen Marja-Riitta
- Teipel Stefan
- Teng Edmond
- Tesí Niccolo
- Teumer Alexander
- Thalamuthu Anbupalam
- Thomas Alvin
- Thomas Charlene
- Thomas Tegos
- Thomassen Jesper Qvist
- Thonberg Håkan
- Tienari Pentti
- Tilson Jeffrey L.
- Tin Adrienne
- Todd Stephen
- Toso Carlos Reyes
- Tosto Giuseppe
- Traykov Latchezar
- Tremolizzo Lucio
- Trojanowski John Q.
- Troncoso Juan C.
- Tsai Ellen
- Tsolaki Anthoula
- Tsolaki Magda
- Tsuang Debby W.
- Tsuo Kristin
- Tucker-Drob Elliot
- Tukiainen Taru
- Tuomi Tiinamaija
- Tuomilehto Jaakko
- Tuovila Outi
- Turpeinen Miia
- Turton James
- Turunen Joni A.
- Tybjærg-Hansen Anne
- Tzourio Christophe
- Tárraga Lluís
- Uitterlinden Andre
- Ullgren Abbe
- Ulstein Ingun
- Uphill James
- Usiskin Keith
- Uusitalo Hannu
- Uusitalo-Järvinen Hannele
- Vacca Alessandro
- Vainio Seppo
- Valero Sergi
- Valladares Otto
- Valladares Otto
- van Adelsberg Janet
- Van Deerlin Vivianna M.
- van den Bussche Hendrik
- van der Flier Wiesje M.
- van der Lee Sven J.
- van der Lugt Aad
- van Duijn Cornelia M.
- van Eldik Linda J.
- van Lent Debora Melo
- van Rooij Jeroen
- van Swieten John
- Vance Jeffery
- Vandenberghe Rik
- Vardarajan Badri N.
- Vardy Emma
- Vargas Liliana
- Vassar Robert
- Verhey Frans
- Vicente Maria Pilar
- Vidal Jean-Sébastien
- Vigo-Ortega R.
- Vigo-Ortega Rosario
- Vilas Raquel Huerto
- Vinters Harry V.
- Virolainen Petri
- Vivancos Liliana
- Vogelgsang Jonathan
- Vojinovic Dina
- Vonsattel Jean-Paul
- Voutilainen Markku
- Vyhnalek Martin
- Wadhawan Samir
- Wagner Michael
- Wallon David
- Wang Clarence
- Wang Li-San
- Wang Ruiqi
- Wang Yanbing
- Warden Donald
- Waring Jeff
- Waring Jeffrey
- Warner Nick
- Warren Jason D.
- Waterworth Dawn
- Weber Heike
- Weinhold Leonie
- Weinstein Galit
- Weintraub Sandra
- Welsh-Bohmer Kathleen A.
- Whelan Christopher
- Whitehead Patrice L.
- Wichmann H-Erich
- Wigmore Eleonor
- Wijsman Ellen M.
- Wilcock Gordon
- Wilhelmsen Kirk C.
- Williams Amy
- Williams Benjamin
- Williams Dylan
- Williams Julie
- Williamson Jennifer
- Wilms Henrik
- Wiltfang Jens
- Windle Gill
- Wingo Thomas S.
- Wisniewski Thomas
- Wittfeld Katharina
- Woltjer Randall L.
- Wong Regis
- Woods Bob
- Woon Martin
- Wright Clinton B.
- Wu Chuang-Kuo
- Wu Ying
- Xia Tai-he
- Xu Ethan
- Xu Fanli
- Yanek Lisa
- Yang Qiong
- Yang Yunju
- Yannakoulia Mary
- Yaqub Amber
- Younkin Steven G.
- Yu Chang-En
- Yu Lei
- Zare Habil
- Zhang Xiaoling
- Zhang Yuanchao
- Zhao Yi
- Zhao Yi
- Zhou Wei
- Zhu Congcong
- Zhu Xiongwei
- Ziemann Adam
- Zoia Chiara Paola
- Zompo Maria Del
- Zulaica Miren
- Álvarez Victoria
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/04/2022
- Field of study
Characterization of the genetic landscape of Alzheimer’s disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/‘proxy’ AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele
New insights into the genetic etiology of Alzheimer’s disease and related dementias
- Author
- A David Smith
- Aaltonen L.
- Aaltonen V.
- Aarno Palotie
- Aarsland D.
- Aavikko M.
- Abalos M. S.
- Abdelnour C.
- Abner E.
- Abraham R.
- Ad Adarmes-Gómez
- Adam Boxer
- Adam Ziemann
- Adams H.
- Adams P. M.
- Adarmes-Gómez A.
- Adarmes-Gómez A. D.
- Adriana Gamboa
- Adrienne L Cupples
- Adrienne Tin
- Aguilera N.
- Aguilera N.
- Aguirre A.
- Agustina Legaz
- Ahmad S.
- Aimee Pierce
- Aino Salminen
- Airi Jussila
- Aisha Khaleeq
- Aki Havulinna
- Akinyemi R. O.
- Al-Chalabi A.
- Alan B Stevens
- Alan Lerner
- Alarcón-Martín E.
- Albert M. S.
- Alberto Benussi
- Albin R. L.
- Alcolea D.
- Aldo Saenz
- Alegret M.
- Alessandra Chesi
- Alessandro Vacca
- Alexander Teumer
- Alexis Brice
- Ali M.
- Alisa Manning
- Alison E Fohner
- Allan I Levey
- Allen M.
- Allende I. R.
- Alonso M. D.
- Alonso M. D.
- Alvarez I.
- Alvarez L.
- Alvin Thomas
- Alyssa Aguirre
- Amanda Cano
- Amanda Elliott
- Amanda G Smith
- Amanda J Myers
- Amer-Ferrer G.
- Amin N.
- Ammar Al-Chalabi
- Amouyel P.
- Amy Gerrish
- Amy Williams
- Ana Mauleón
- Ana Pancho
- Anastasia Shcherban
- Anastasiou A.
- Anastasiou C.
- Anders Malarstig
- Andrade V.
- Andrea Ganna
- Andreassen O. A.
- Andreoni S.
- Andrew J Saykin
- Andrew McQuillin
- Andrew N McDavid
- Andrew P Lieberman
- Andrew Peterson
- Andrey Loboda
- André Lacour
- Angela Hodges
- Aniket Mishra
- Ann C McKee
- Anna Anastasiou
- Anna Antonell
- Anna Gailhajenet
- Anna M Karydas
- Anna Podgornaia
- Anne Lehtonen
- Anne Pitkäranta
- Anne Remes
- Annette Fitzpatrick
- Annika Auranen
- Antequera M.
- Anthony Bayer
- Anthony Muslin
- Antikainen R.
- Antonell A.
- Antti Karlsson
- Antti Palomäki
- Anttonen V.
- Antúnez C.
- Anu Jalanko
- Anu Loukola
- Aoibhinn Lynch
- Aparicio H. J.
- Aparna Chhibber
- Apinya Lertratanakul
- Apostolova L. G.
- Appollonio I.
- Arcaro M.
- Archetti S.
- Arjun Masurkar
- Armstrong N.
- Armstrong N. J.
- Arnold S. E.
- Arosio B.
- Arto Lehisto
- Arto Lehistö
- Arto Mannermaa
- Arvas M.
- Ashok Raj
- Assogna F.
- Asthana S.
- Astrid D Adarmes-Gómez
- Asunción Lafuente
- Atahualpa Castillo Morales
- Athanasiu L.
- Athena Matakidou
- Atwood C. S.
- Audrey Chu
- Auge F.
- Auranen A.
- Auvinen P.
- Awaisa G.
- Ayres G.
- Bacha J. I.
- Bahadori M.
- Bahrami S.
- Bailly H.
- Baldwin C. T.
- Banaj N.
- Baquero M.
- Barbara Davis
- Barber R. C.
- Barnes L. L.
- Barral S.
- Barral S.
- Barry Reisberg
- Bass N.
- Bass N. J.
- Bastiani P.
- Bayer A.
- Beach T. G.
- Becker J. T.
- Becker J. T.
- Becker T.
- Beecham G. W.
- Beekly D.
- Begoña Martínez
- Behrens T.
- Beiser A.
- Belezhanska D.
- Bellenguez C.
- Below J. E.
- Below J. E.
- Ben Challis
- Ben-Shlomo Y.
- Benchek P.
- Benitez B. A.
- Benjamin Williams
- Bennett D.
- Benussi A.
- Benussi L.
- Bergh S.
- Bernadette McGuinness
- Bernard Mazoyer
- Bernardino Ghetti
- Bernardo-Harrington M.
- Berr C.
- Bertelson J.
- Beryl Cummings
- Besse C.
- Bessi V.
- Beth A Dombroski
- Betts J.
- Bhangale T.
- Biessels G. J.
- Binetti G.
- Bing N.
- Bird T. D.
- Bis J. C.
- Biswas S.
- Bizarro A.
- Bjerke M.
- Blacker D.
- Blesa R.
- Blomster T.
- Boada M.
- Bob Georgantas
- Boecker H.
- Boerwinkle E.
- Boeve B. F.
- Boland A.
- Borroni B.
- Boschi S.
- Bosnes I.
- Bossù P.
- Bowen J. D.
- Bowers N.
- Boxer A.
- Bradley F Boeve
- Bradley T Hyman
- Brauer M.
- Brayne C.
- Brein G.
- Bresner C.
- Bressler J.
- Breteler M.
- Brewer J.
- Brian Fulton-Howard
- Brian Lawlor
- Brice A.
- Bridget Riley-Gillis
- Britta Schürmann
- Brodaty H.
- Broeckhoven C. V.
- Bronson P.
- Brookes K. J.
- Brown K.
- Brown K. S.
- Bruce L Miller
- Bruno A Benitez
- Bruno Dubois
- Brusco L. I.
- Bråthen G.
- Buendia M.
- Buiza-Rueda D.
- Bullido M. J.
- Burguera J. A.
- Burholt V.
- Burke J. R.
- Burns J. M.
- Bush W. S.
- Bush W. S.
- Buxbaum J. D.
- Bûrger K.
- C Dirk Keene
- Cairns N. J.
- Calero M.
- Caliskan M.
- Call K.
- Call K.
- campion D.
- Campos-Martin R.
- Cano A.
- Cantwell L. B.
- Cao C.
- Carlo Ferrarese
- Carlos Cruchaga
- Carlos Ingino
- Carlos Mangone
- Carlos Reyes Toso
- Carlson C. S.
- Carlsson C. M.
- Carmen Lage
- Carney R. M.
- Carol A Miller
- Carol Brayne
- Carolina Cuesta
- Caroline Fox
- Carpén O.
- Carracedo Á.
- Carrasquillo M. M.
- Carrillo F.
- Carrillo F.
- Carrion-Claro M.
- Casajeros M. J.
- Castaño E. M.
- Catherine Marshall
- Catherine Mummery
- Cañabate P.
- Cecchetti R.
- Cecilia Ortiz
- Cervera-Carles L.
- Challis B.
- Chang D.
- Chang-En Yu
- Chapuis J.
- Charbonnier C.
- Charlene Thomas
- Charles DeCarli
- Charles S DeCarli
- Charlotte Forsell
- Chasman D.
- Chasse S.
- Chatelain C.
- Chauhan G.
- Chen C. -Y.
- Chen H.
- Chen H.
- Chen H. -H.
- Chen X.
- Chene G.
- Chesi A.
- Chesselet M. -F.
- Chhibber A.
- Chia-Yen Chen
- Chiara Paola Zoia
- Chien-Yueh Lee
- Chillotti C.
- Chin N. A.
- Chipi E.
- Chloe Davies
- Choy D.
- Christine Herold
- Christine M Hulette
- Christoph Laske
- Christophe Tzourio
- Christopher E Shaw
- Christopher S Carlson
- Christopher Whelan
- Chu A.
- Chuang-Kuo Wu
- Chuanhai Cao
- Chui H. C.
- Chung J.
- Chung J.
- Ciccone S.
- Ciullo V.
- Claassen J. A. H. R.
- Clarence Wang
- Clarimon J.
- Clark C.
- Clarke R.
- Clement Chatelain
- Clinton B Wright
- Clinton T Baldwin
- Close D.
- Clàudia Olivé
- Collinge J.
- Comic H.
- Constantine G Lyketsos
- Conti E.
- Cores V.
- Corma-Gómez A.
- Costa M. R.
- Costantini E.
- Costas Anastasiou
- Cox S.
- Craft S.
- Craig D.
- Craig S Atwood
- Crane P. K.
- Cribbs D. H.
- Crocco E. A.
- Crohns M.
- Cruchaga C.
- Csilla Sipeky
- Cuccaro M. L.
- Cuesta C.
- Cullum M.
- Cummings B.
- Cupples A. L.
- Custodero C.
- Cynthia M Carlsson
- D Macias-García
- Daian D.
- Dalmasso M. C.
- Daly M.
- Damotte V.
- Dan Liu
- Dana Lis Palacio
- Daniel C Marson
- Daniel Chasman
- Daniel G Politis
- Daniel H Geschwind
- Daniel Janowitz
- Daniel Macias-García
- Daniele A.
- Danjuma Quarless
- Danny Oh
- Darby E.
- Dardiotis E.
- Dartigues J. -F.
- David Bennett
- David C Rubinsztein
- David Choy
- David Close
- David Craig
- David H Cribbs
- David Mann
- David Paydarfar
- David Pulford
- David Rice
- David Sultzer
- Davies C.
- Davies G.
- Davis B.
- Davis J. W.
- Dawn Waterworth
- de Deyn P. P.
- De Jager P. L.
- de Mendonça A.
- de Munain A. L.
- de Paiva Lopes K.
- de Rojas I.
- de Witte L. D.
- Debby W Tsuang
- Debette S.
- Debora Melo van Lent
- Deborah Blacker
- Deborah C Mash
- DeCarli C.
- DeCarli C. S.
- Deckert J.
- Deepak Rajpal
- del Ser T.
- Deleuze J. -F.
- della Briotta Parola P.
- della Briotta Parolo P.
- Deloukas P.
- Deloukas P.
- Denis A Evans
- Denise Harold
- Denning N.
- Dennis W Dickson
- Deramecourt V.
- Deramerourt V.
- DeStefano A.
- DeToledo J.
- Dhanaprakash Jambulingam
- Diana Chang
- Dichgans M.
- Dick M.
- Dickson D. W.
- Didier Hannequin
- Diego Real de Asúa
- Diego S.
- Diehl-Schmid J.
- Diez-Fairen M.
- Dina Vojinovic
- Diogo D.
- Diptee Kulkarni
- Diyana Belezhanska
- Djurovic S.
- Dmitriy Drichel
- Dombroski B. A.
- Dominique Campion
- Donald R Royall
- Donald Warden
- Dongen J. V.
- Dongyu Liu
- Donner K.
- Doody R. S.
- Dorothee Diogo
- Douglas Mains
- Douglas R Galasko
- Dowzell K.
- Drichel D.
- Duane Beekly
- Duara R.
- Dubois B.
- Dufouil C.
- Duperron M. -G.
- Dupuis J.
- Duron E.
- Dylan Williams
- Düzel E.
- Eaton S.
- Edith Hofer
- Edmond Teng
- Eduardo Kohler
- Eduardo M Castaño
- Edward B Lee
- Edwin S Monuki
- Eeva Kangasniemi
- Eeva Sliz
- Ehm M.
- Eicher J.
- Eija Laakkonen
- Eiriksdottir G.
- Ekaterina Rogaeva
- Eklund K.
- Elaine Peskind
- Elena Chipi
- Elenius K.
- Eleonor Wigmore
- Elhaj Mohammed
- Eliezer Masliah
- Elina Järvensivu
- Elina Kilpeläinen
- Elizabeth A Crocco
- Elizabeth Fisher
- Elizabeth Head
- Elizabeth Litkowski
- Ellen De Roeck
- Ellen M Wijsman
- Ellen Tsai
- Elliot Hong
- Elliot Tucker-Drob
- Elliott A.
- Elmutaz Shaikho
- Elvira Martín
- Emily Holzinger
- Emma Vardy
- Engelborghs S.
- Epelbaum J.
- Eric B Larson
- Eric M Reiman
- Erich Strauss
- Erik D Roberson
- Erika Kvikstad
- Erin Abner
- Ertekin-Taner N.
- Escott-Price V.
- Escuela R.
- Esmaeeli S.
- Espinosa A.
- Espinosa M. A. L.
- Essi Kaiharju
- Ester Pelejá
- Esther Pelejà
- Etchepareborda I.
- Ethan Xu
- Evans D. A.
- Evans T.
- Eveleen Darby
- Ewers M.
- F Carrillo
- Faber K. M.
- Fabrizio Piras
- Fabrizio T.
- Fairchild T. J.
- Fallon K. B.
- Fan F.
- Fanli Xu
- Fardo D. W.
- Farlow M. R.
- Farotti L.
- Farrell J. J.
- Farrer L. A.
- Fausto Roveta
- Federica Piras
- Federico Ariel Prestia
- Fedik Rahimov
- Fenoglio C.
- Fernandez-Hernandez V.
- Fernández-Fuertes M.
- Ferrarese C.
- Ferrari R.
- Ferreira C. B.
- Ferri E.
- Ferris S.
- Feulner T.
- Fievet N.
- Fin B.
- Fischer P.
- Fisher E.
- Fitzpatrick A.
- Fladby T.
- Flanagan E Margaret
- Fließbach K.
- Fohner A. E.
- Fongang B.
- Fornage M.
- Foroud T. M.
- Forsell C.
- Fortea J.
- Fostinelli S.
- Fox C.
- Fox N.
- Fox N. C.
- Francesca Assogna
- Franck Auge
- Franco-Macías E.
- Frank Fan
- Frank M LaFerla
- Frank Martiniuk
- Frank-García A.
- Frikke-Schmidt R.
- Froelich L.
- Frosch M. P.
- Frölich L.
- Fulton-Howard B.
- Fátima Carrillo
- Färkkilä M.
- Gail Davies
- Gail P Jarvik
- Gailhajenet A.
- Galasko D. R.
- Galeano P.
- Galimberti D.
- Galit Weinstein
- Gamboa A.
- Ganesh Chauhan
- Ganguli M.
- Ganna A.
- Garcia-Gonzalez P.
- Garcia-Madrona S.
- Garcia-Ribas G.
- Garcia-Tabuenca J.
- García-Alberca J. M.
- García-González P.
- Garrote-Espina L.
- Gary W Beecham
- Gayle Ayres
- Gearing M.
- Geerlings M.
- Gena Roshchupkin
- Geoff Kerchner
- Georg Brein
- Georgantas B.
- George-Hyslop P. S.
- Germani S.
- Gerrish A.
- Geschwind D. H.
- Gessica Sala
- Ghanbari M.
- Ghazal Awaisa
- Ghetti B.
- Ghidoni R.
- Ghosh S.
- Giedraitis V.
- Giegling I.
- Gilbert J. R.
- Gill Livingston
- Gill M.
- Giordano Lacidogna
- Giorgio G.
- Gisela Novack
- Glatt S. J.
- Goate A. M.
- Goldhardt O.
- Gomez-Fonseca D.
- Gonzalez H. M.
- González-Pérez A.
- Gordillo J. E.
- Gordon Wilcock
- Gormley P.
- Goss M.
- Gossel M.
- Grabe H.
- Grabowski T. J.
- Gracia-Tabuenca J.
- Graff C.
- Graff-Radford N. R.
- Graham Heap
- Graham R.
- Grand Q. L.
- Grande G.
- Grant S. F. A.
- Green E.
- Green R. C.
- Greenberg S.
- Grenier-Boley B.
- Grimmer T.
- Growdon J. H.
- Grunin M.
- Grünblatt E.
- Gu W.
- Gudnason V.
- Guerreiro R.
- Guetta-Baranes T.
- Guillermo Amer-Ferrer
- Guitart M.
- Gurling H.
- Gursoy U.
- Gwilliam R.
- Gómez-Garre P.
- Gómez-Garre P.
- H-Erich Wichmann
- Haapasalo A.
- Habes M.
- Hadjigeorgiou G.
- Haines J. L.
- Haines J. L.
- Hakon Hakonarson
- Hakonarson H.
- Hall J.
- Hamilton R. L.
- Hamilton-Nelson K. L.
- Hampel H.
- Hannele Laivuori
- Hannele Mattsson
- Hannele Uusitalo-Järvinen
- Hannequin D.
- Hannu Kankaanranta
- Hannu Uusitalo
- Hannula-Jouppi K.
- Hanon O.
- Hans Grabe
- Hao Chen
- Hao Mei
- Harari O.
- Hardy J.
- Harju J.
- Harju T.
- Harold D.
- Harrell L. E.
- Harri Siirtola
- Harry V Vinters
- Hartmann A. M.
- Harvima I.
- Harwood J.
- Hata Comic
- Hausner L.
- Haut J.
- Hautala N.
- Havulinna A.
- Head E.
- Heap G.
- Heckbert S. R.
- Hector M Gonzalez
- Hedman Å.
- Heike Kölsch
- Heike Weber
- Heikki Joensuu
- Heikkinen S.
- Heiko Runz
- Heilmann-Heimbach S.
- Helena C Chui
- Helena Schmidt
- Heli Lehtonen
- Helisalmi S.
- Hema Sekhar
- Henderson V. W.
- Hendolin M.
- Hendrik van den Bussche
- Heneka M. T.
- Henning Boecker
- Henrik Wilms
- Henrike Heyne
- Henry L Paulson
- Hernandez M.
- Hernández I.
- Herold C.
- Heron S.
- Herrmann M. J.
- Heun R.
- Heuser I.
- Hevilla S.
- Heyne H.
- Hieab Adams
- Hiekkalinna T.
- Hiltunen M.
- Hinttala R.
- Hochfeld M.
- Hodges A.
- Hofer E.
- Hoffman J.
- Hoffmann P.
- Hohman T.
- Hollingworth P.
- Holmans P. A.
- Holmes C.
- Holstege H.
- Holzinger E.
- Hong E.
- Honig L. S.
- Hooper N. M.
- Hort J.
- Howard J Rosen
- Howard Jacob
- Hu X.
- Huang Y.
- Hubert Chen
- Huebinger R. M.
- Huentelman M. J.
- Hugh Gurling
- Hughes T.
- Hugo J Aparicio
- Huhtakangas J.
- Huilaja L.
- Hulette C. M.
- Hulsman M.
- Humphrey J.
- Hunkapiller J.
- Huntington Potter
- Hyman B. T.
- Hynan L. S.
- Hyvärinen K.
- Håkan Thonberg
- Hüll M.
- Ibanez L.
- Ibarria M.
- Ignacio Etchepareborda
- Ikram M. A.
- Ilkka Harvima
- Ingelsson M.
- Ingino C.
- Ingunn Bosnes
- Iriarte M. M.
- Isabel Sastre
- Isabel Sastre Merlín
- Isabella Heuser
- Isomäki P.
- Jaakko Kaprio
- Jaakko Parkkinen
- Jaakko Tuomilehto
- Jaana Lindström
- Jacob H.
- Jacob Haut
- Jacob Shofany
- Jacques Epelbaum
- Jaeyoon Chung
- Jalanko A.
- Jambulingam D.
- James B Leverenz
- James Brewer
- James D Bowen
- James Hall
- James J Lah
- James R Burke
- James T Becker
- James T Becker
- James Turton
- James Uphill
- Jan Laczo
- Janet A Johnston
- Janet P Smith
- Janet van Adelsberg
- Janice Knebl
- Janowitz D.
- Jansen I. E.
- Jari Lahti
- Jari Laukkanen
- Jarmo Harju
- Jarmo Ritari
- Jarret A Johnston
- Jarvik G. P.
- Jason D Warren
- Javier Garcia-Tabuenca
- Javier Gracia-Tabuenca
- Jayadev S.
- Jean Shin
- Jean-Paul Vonsattel
- Jeannette Simino
- Jeff Waring
- Jeffrey A Kaye
- Jeffrey L Tilson
- Jeffrey M Burns
- Jeffrey O'Connell
- Jeffrey Waring
- Jennifer E Below
- Jennifer E Phillips-Cremins
- Jennifer Schutzman
- Jennifer Smith
- Jennifer Williamson
- Jenny Lord
- Jerome Rotter
- Jesse Mez
- Jessen F.
- Jesús S.
- Jesús S.
- Jian X.
- Jimmy Liu
- Jiménez M. G.
- Jin L. -W.
- Jiwoo Lee
- Jo Betts
- Joan S Reisch
- Joel H Kramer
- Joensuu H.
- Johanna Huhtakangas
- Johanna Mattson
- Johanna Mäkelä
- Johanna Schleutker
- Johannes Kettunen
- Johansson C.
- John Bertelson
- John C Morris
- John Collinge
- John DeToledo
- John Eicher
- John F Powell
- John H Growdon
- John J Farrell
- John M Olichney
- John M Ringman
- John Malamon
- John Michon
- John Powell
- John Q Trojanowski
- John R Gilbert
- John S.
- Johnson K.
- Johnson L.
- Johnston J. A.
- Johnston J. A.
- Jonathan L Haines
- Jones L.
- Joni A Turunen
- Jorge Esparza Gordillo
- Jose Romero
- Joseph D Buxbaum
- Joseph E Parisi
- Joseph F Quinn
- Joseph Maranville
- Joshua A Sonnen
- Joshua Hoffman
- Joshua M Shulman
- Joshua W Miller
- Josée Dupuis
- Jr
- Juan Andrés Burguera
- Juan C Troncoso
- Juan Ignacio Bacha
- Juan Macias
- Juan Marín-Muñoz
- Juan P. S.
- Juha Karjalainen
- Juha Rinne
- Juha Sinisalo
- Juhani Junttila
- Jukka Partanen
- Jukka Peltola
- Julie A Schneider
- Julie Hunkapiller
- Julieta Lisso
- Julkunen V.
- Jun G. R.
- Junttila J.
- Juonala M.
- Jussi Pihlajamäki
- Jussila A.
- Justin Wade Davis
- Järvensivu E.
- Jöckel K. -H.
- Kaarniranta K.
- Kaarteenaho R.
- Kai Kaarniranta
- Kaiharju E.
- Kaipiainen-Seppänen O.
- Kaisa Tasanen
- Kaj Metsärinne
- Kajanne R.
- Kalaoja M.
- Kalina Yonkova Mihova
- Kalle Pärn
- Kalpala K.
- Kamboh M. I.
- Kanai M.
- Kangasniemi E.
- Kankaanranta H.
- Kaprio J.
- Karen S King
- Kari Eklund
- Kari Linden
- Kari Pulkki
- Karihtala P.
- Karjalainen J.
- Karjalainen M.
- Karl-Heinz Jöckel
- Karlsson A.
- Karydas A. M.
- Kastumata Y.
- Katariina Hannula-Jouppi
- Katharina Wittfeld
- Katherine Call
- Kathleen A Welsh-Bohmer
- Kathy Call
- Kathy Klinger
- Kati Donner
- Kati Hyvärinen
- Kati Kristiansson
- Katri Pylkäs
- Katri Raikkonen-Talvitie
- Katz M. J.
- Kaunisto M.
- Kauppi P.
- Kauppila S.
- Kautz T. F.
- Kauwe J.
- Kaye J. A.
- Kayenat Parveen
- Keene C. D.
- Kehoe P. G.
- Keith Usiskin
- Kenneth B Fallon
- Kerchner G.
- Kettunen J.
- Khaleeq A.
- Kiiskinen T.
- Kilander L.
- Kilpeläinen E.
- Kilpi T.
- Kim Johnson
- Kim R.
- Kimberley Dowzell
- Kimmo Palin
- King K. S.
- Kirk C Wilhelmsen
- Kirsi Kalpala
- Kirsi Sipilä
- Kiviniemi M.
- Kivipelto M.
- Klaus Elenius
- Kleineidam L.
- Klinger K.
- Klopp N.
- Knebl J.
- Knol M.
- Kochen S.
- Kohler E.
- Kohler M.
- Koivisto A.
- Kornhuber J.
- Koskinen M.
- Kosma V. -M.
- Kosmidis M. H.
- Koulu L.
- Kowall N. W.
- Kramer J. H.
- Kremen W.
- Kristelle Brown
- Kristelle S Brown
- Kristiansson K.
- Kristin Tsuo
- Kujala U.
- Kuksa P. P.
- Kukull W. A.
- Kulkarni D.
- Kunkle B. W.
- Kurki M.
- Kuulasmaa T.
- Kuzma A. B.
- Kvikstad E.
- Kähönen M.
- Kälviäinen R.
- Kölsch H.
- Küçükali F.
- L Garrote-Espina
- Laakkonen E.
- Laakso M.
- Laatikainen T.
- Labrador M.
- Lacaze P.
- Lacidogna G.
- Lacour A.
- Laczo J.
- LaFerla F. M.
- Lafuente A.
- Lage C.
- Lage C.
- Lah J. J.
- Lahdenperä S.
- Lahti J.
- Laiho P.
- Laitinen T.
- Laivuori H.
- Lambert J. -C
- Larson E. B.
- Laske C.
- Laukka E. J.
- Laukkanen J.
- Laukkanen M.
- Launer L.
- Laura Huilaja
- Laura Ibanez
- Laura Pirilä
- Lauri Aaltonen
- Lauria A.
- Lawlor B.
- Lawrence S Honig
- Lee C. -Y.
- Lee C. -Y.
- Lee E. B.
- Lee J.
- Lee-Way Jin
- Leena Koulu
- Legaz A.
- Lehisto A.
- Lehtisalo J.
- Lehtonen A.
- Lehtonen H.
- Lei Yu
- Leigh Johnson
- Lemmelä S.
- Lerch O.
- Lerner A.
- Lertratanakul A.
- Lesley Jones
- Leung Y. Y.
- Leverenz J. B.
- Levey A. I.
- Li M.
- Li S.
- Liana G Apostolova
- Lieberman A. P.
- Liisa Suominen
- Liliana Vargas
- Liliana Vivancos
- Liming Qu
- Linda J van Eldik
- Linda McCarthy
- Linda S Hynan
- Linden K.
- Lindström J.
- Lindy E Harrell
- Lipton R. B.
- Lisa Alvarez
- Lisa L Barnes
- Lisa Yanek
- Lisso J.
- Litkowski E.
- Liu D.
- Liu D.
- Liu J.
- Liu X.
- Livingston G.
- Lleó A.
- Llorens V.
- Loboda A.
- Loerch P.
- Logue M.
- Loitfelder M.
- Lon S Schneider
- Longstreth W.
- Loomis S.
- Lopez O.
- Lord J.
- Lorena Garrote-Espina
- Lotta Männikkö
- Loukola A.
- Love S.
- Lovestone S.
- Lu T.
- Luckcuck L.
- Lunetta K. L.
- Luodonpää M.
- Lupton M.
- Lutz Frölich
- Lyketsos C. G.
- Lynch A.
- Lähteenmäki S.
- López-García S.
- López-García S.
- Löwemark M.
- M Carrion-Claro
- M Ilyas Kamboh
- M Marín
- Ma Labrador
- Ma Y.
- Macias J.
- Macias-García D.
- MacLeod C. A.
- Macías J.
- Maier W.
- Maillard P.
- Mains D.
- Maite Mendioroz Iriarte
- Malamon J.
- Malarstig A.
- Malcolm Dick
- Malik R.
- Mangialasche F.
- Mangone C.
- Mann D.
- Mannermaa A.
- Manning A.
- Mantere T.
- Manuel González Jiménez
- Manuel Mayhaus
- Manuel Rivas
- Manzanares S.
- Mar Buendia
- Maranville J.
- Marcia Ory
- Margaret F. E.
- Margit Pelkonen
- Mari E Niemi
- Mari Kaunisto
- Mari Takalo
- Maria Bjerke
- Maria Del Zompo
- Maria Knol
- Maria Pilar Vicente
- Maria Serpente
- Maria Siponen
- Marian Martinez de Pancorbo
- Mariana Sanchez Abalos
- Marie-Francoise Chesselet
- Marie-Gabrielle Duperron
- Mariet Allen
- Marika Crohns
- Marilyn S Albert
- Marina Guitart
- Mario Carrión-Claro
- Mario Rios
- Mariona Moreno
- Marioni R.
- Marisa Loitfelder
- Marita Kalaoja
- Marja Luodonpää
- Marja-Riitta Taskinen
- Mark A Sager
- Mark Daly
- Mark Logue
- Mark McCarthy
- Markku Laakso
- Markku Laukkanen
- Markku Peltonen
- Markku Voutilainen
- Markus Juonala
- Markus Perola
- Marla Gearing
- Marla Hochfeld
- Maroñas O.
- Marquié M.
- Mars N.
- Marsel Mesulam
- Marsha Polk
- Marshall C.
- Marshall R.
- Marson D. C.
- Marta Ibarria
- Marta Marín
- Martin E. R.
- Martin R Farlow
- Martin Rossor
- Martin Rossor
- Martin Woon
- Martinez de Pancorbo M.
- Martiniuk F.
- Martirio Antequera
- Martti Färkkilä
- Martín E.
- Martínez B.
- Martínez V.
- Martínez-Lage Álvarez P.
- Martínez-Larrad M. T.
- Mary Ganguli
- Mary Pat Reeve
- Mary Quiceno
- Mary Sano
- Maryam Bahadori
- María Dolores Alonso
- María Dolores Alonso
- María José Casajeros
- María Teresa Martínez-Larrad
- María Teresa Periñán-Tocino
- Marín M.
- Marín M.
- Marín T.
- Marín-Muñoz J.
- Masahiro Kanai
- Mash D. C.
- Masliah E.
- Massman P.
- Masullo C.
- Masurkar A.
- Matakidou A.
- Mateus Bernardo-Harrington
- Mather K.
- Matias Kohler
- Matias Rojo
- Matoska V.
- Matt Brauer
- Matthew J Huentelman
- Matthew P Frosch
- Matthias Gossel
- Matthias Riemenschneider
- Mattson J.
- Mattsson H.
- Mauleón A.
- Mayeux R.
- Mayhaus M.
- Mazoyer B.
- McCarthy L.
- McCarthy M.
- McCormick W. C.
- McCurry S. M.
- McDavid A. N.
- McDonough S.
- McDonough S.
- McGuinness B.
- McKee A. C.
- McQuillin A.
- Mead S.
- Mecocci P.
- Medel N.
- Medina M.
- Meg Ehm
- Meggy A.
- Mehrabian S.
- Mehta V.
- Mei H.
- Melissa Miller
- Mendoza S.
- Menéndez-González M.
- Meretoja T.
- Merlín I. S.
- Mervi Aavikko
- Mesulam M.
- Metsärinne K.
- Mez J.
- Michael C O'Donovan
- Michael Gill
- Michael Hüll
- Michael J Owen
- Michael L Cuccaro
- Michael O'Donovan
- Michael Owen
- Michelle Hernandez
- Michelle Lupton
- Michon J.
- Miguel Angel Labrador Espinosa
- Mihova K. Y.
- Miia Turpeinen
- Miika Koskinen
- Mika Kähönen
- Mikko Arvas
- Mikko Kiviniemi
- Miller B. L.
- Miller C. A.
- Miller J. W.
- Miller M.
- Minal Caliskan
- Mindy J Katz
- Minerva M Carrasquillo
- Mingyao Li
- Minna Hendolin
- Minna Karjalainen
- Mir P.
- Mirjam Geerlings
- Mishra A.
- Mitja Kurki
- Moebus S.
- Moeen Riaz
- Mohamad Habes
- Mohammed E.
- Mol M.
- Molina-Porcel L.
- Monica Goss
- Monica Rodriguear
- Monique Breteler
- Montes A. M.
- Montine T. J.
- Montrreal L.
- Monuki E. S.
- Morales A. C.
- Morelli L.
- Moreno F.
- Moreno M.
- Moreno-Grau S.
- Morgan K.
- Morris J. C.
- Mosley T.
- Mt Periñán
- Muchnik C.
- Muhammad Ali
- Mukherjee S.
- Mummery C.
- Munro Cullum
- Murali Sargurupremraj
- Murray Raskind
- Muslin A.
- Myers A. J.
- Mäkelä J.
- Mäkelä T.
- Männikkö L.
- Mäntylä P.
- Nacmias B.
- Naj A. C.
- Nan Bing
- Nancy Medel
- Nash W.
- Natalie Bowers
- Natalie S Ryan
- Nathalie Fievet
- Nathalie Ryan
- Nathaniel A Chin
- Natividad Olivar
- Natunen T.
- Neil W Kowall
- Neill R Graff-Radford
- Ngandu T.
- Nguyen T.
- Nicholas J Bass
- Nick Bass
- Nick Fox
- Nick Warner
- Nicola Armstrong
- Nicola Salvadori
- Nicolas G.
- Nielsen S. F.
- Niemi M. E.
- Nieminen P.
- Nigel J Cairns
- Nigel M Hooper
- Niiranen T.
- Nilüfer Ertekin-Taner
- Nina Hautala
- Nina Mars
- Nizar Smaoui
- Nordestgaard B. G.
- Norman Klopp
- Novack G.
- Nuria Aguilera
- Nuria Aguilera
- Nuñez-Llaves R.
- Nyquist P.
- Nöthen M. M.
- Oh D.
- Oili Kaipiainen-Seppänen
- Olalla Maroñas
- Olaso R.
- Olichney J. M.
- Olivar N.
- Olivé C.
- Olli Carpén
- Ollila T.
- Orellana A.
- Orsini M.
- Ortega G.
- Ortiz C.
- Ory M.
- Oscar Harari
- Otto Valladares
- Outi Tuovila
- Owen M.
- Owen M. J.
- O’Bryant S.
- O’Connell J.
- O’Donovan M.
- O’Donovan M. C.
- P Gómez-Garre
- Paajanen T.
- Pablo Galeano
- Pablo Martínez-Lage Álvarez
- Padhraig Gormley
- Padovani A.
- Pakkanen R.
- Palacio D. L.
- Palin K.
- Palmer R.
- Palomäki A.
- Palotie A.
- Palotie U.
- Palta P.
- Panagiotis Deloukas
- Pancho A.
- Pangiotis Deloukas
- Paola Bronson
- Paolo C.
- Papenberg G.
- Parisi J. E.
- Parkkinen J.
- Parnetti L.
- Partanen J.
- Parveen K.
- Pasquier F.
- Passmore P.
- Passmore P.
- Pastor A. A.
- Pastor A. B.
- Pastor P.
- Patel Y.
- Patel Y.
- Patrice L Whitehead
- Patricia Solis
- Patrick Loerch
- Patrizia Bastiani
- Paul Hollingworth
- Paul K Crane
- Paul Lacaze
- Paul Massman
- Paul Nyquist
- Paula Kauppi
- Pauline Maillard
- Paulson H. L.
- Paus T.
- Pausova Z.
- Pavel P Kuksa
- Pavlik V.
- Paydarfar D.
- Peeter Karihtala
- Pekka Nieminen
- Pelejà E.
- Pelkonen M.
- Peloso G.
- Peltola J.
- Peltonen M.
- Peltonen S.
- Pendergrass S.
- Penelope Benchek
- Pentti Tienari
- Per Selnes
- Perez V.
- Pericak-Vance M. A.
- Pericard P.
- Periñán M.
- Periñán-Tocino M. T.
- Perneczky R.
- Perola M.
- Perrie M Adams
- Peskind E.
- Peter Passmore
- Peter Passmore
- Peter St George-Hyslop
- Peters O.
- Petersen R. C.
- Peterson A.
- Petra Proitsi
- Petri Virolainen
- Petrovski S.
- Philip L De Jager
- Phillips-Cremins J. E.
- Pia Isomäki
- Pickering-Brown S.
- Pierce A.
- Pietro Della Briotta Parola
- Pietro Della Briotta Parolo
- Pihlajamäki J.
- Pijnenburg Y. A. L.
- Pikkarainen S.
- Pilar Cañabate
- Pilar Cañabate
- Pilar Gómez-Garre
- Pinchler S.
- Pineda J. A.
- Pineda-Sánchez R.
- Piras F.
- Piras F.
- Pirilä L.
- Pirkko Pussinen
- Pisanu C.
- Pitkäranta A.
- Piñol-Ripoll G.
- Plenge R.
- Podgornaia A.
- Polak T.
- Politis D. G.
- Polk M.
- Poon W. W.
- Popovic R.
- Popp J.
- Posthuma D.
- Potter H.
- Powell J.
- Powell J. F.
- Preckler S.
- Prestia F. A.
- Priit Palta
- Priller J.
- Proitsi P.
- Prokic I.
- Psaty B. M.
- Puerta R.
- Pulford D.
- Pulkki K.
- Pussinen P.
- Pylkäs K.
- Päivi Auvinen
- Päivi Laiho
- Päivi Mäntylä
- Pärn K.
- Pérez-Cordón A.
- Pérez-Tur J.
- Qu L.
- Quarless D.
- Quenez O.
- Quentin Le Grand
- Quiceno M.
- Quinn J. F.
- Quintela I.
- R Escuela
- R Pineda-Sánchez
- R Vigo-Ortega
- Rachelle S Doody
- Rahimov F.
- Raikkonen-Talvitie K.
- Raimo Pakkanen
- Rainer Malik
- Rainero I.
- Raisa Serpi
- Raj A.
- Raj T.
- Rajabli F.
- Rajpal D.
- Rajula R.
- Ramakers I.
- Ramirez A.
- Randall L Woltjer
- Ranjan Duara
- Raskind M.
- Rathinakannan V. S.
- Raymond Palmer
- Raúl Nuñez-Llaves
- Real de Asúa D.
- Real L. M.
- Rebecca Sussams
- Reddy Rajula
- Reetta Hinttala
- Reetta Kälviäinen
- Reeve M. P.
- Regina M Carney
- Regis Wong
- Reiman E. M.
- Reinders M. J. T.
- Reinhard Heun
- Reinhold Schmidt
- Reisberg B.
- Reisch J. S.
- Reitz C.
- Relja Popovic
- Remes A.
- Reyes-Dumeyer D.
- Rhian Gwilliam
- Riaz M.
- Riccardo Marioni
- Rice D.
- Rich S.
- Richard Abraham
- Richard B Lipton
- Ridge P.
- Riedel-Heller S.
- Riederer P.
- Riemenschneider M.
- Riitta Antikainen
- Riitta Kaarteenaho
- Riley-Gillis B.
- Ringman J. M.
- Rinne J.
- Rios M.
- Ripatti S.
- Risto Kajanne
- Rita Guerreiro
- Ritari J.
- Rivas M.
- Roberson E. D.
- Robert A Stern
- Robert C Barber
- Robert C Green
- Robert Clarke
- Robert Graham
- Robert Perneczky
- Robert Plenge
- Robert Vassar
- Roberto N.
- Rocío Escuela
- Rocío Pineda-Sánchez
- Rodrigo S.
- Rodrigo-Herrero S.
- Rodriguear M.
- Rodriguez-Rodriguez E.
- Rodríguez C. M.
- Roeck E. D.
- Rogaeva E.
- Roger L Albin
- Roger N Rosenberg
- Rojo M.
- Romero J.
- Ronald C Petersen
- Ronald Kim
- Ronald L Hamilton
- Rongve A.
- Rosario Vigo-Ortega
- Rosen H. J.
- Rosenberg R. N.
- Rosende-Roca M.
- Roshchupkin G.
- Rossi G.
- Rossi P. D.
- Rossor M.
- Rossor M.
- Rotter J.
- Roveta F.
- Royall D. R.
- Royo J. L.
- Rubino E.
- Rubinsztein D. C.
- Rudolph E Tanzi
- Rufus O Akinyemi
- Ruiz A.
- Rujescu D.
- Runz H.
- Russell H Swerdlow
- Ryan M Huebinger
- Ryan N.
- Ryan N. S.
- Rábano A.
- Rüeger S.
- S Jesús
- Saba Y.
- Sabrina Pinchler
- Sachdev P.
- Saenz A.
- Sager M. A.
- Sahar Esmaeeli
- Saila Kauppila
- Sakka P.
- Sala G.
- Sally John
- Salmi T.
- Salminen A.
- Salo T.
- Salomaa V.
- Saltvedt I.
- Salvadora Manzanares
- Salvadori N.
- Salvatore Spina
- Sami Heikkinen
- Samir Wadhawan
- Sampsa Pikkarainen
- Samuel Heron
- Samuli Ripatti
- Sanabria Á.
- Sanchez-Garcia F.
- Sando S. B.
- Sandra Barral
- Sandra Germani
- Sandra Weintraub
- Sanjay Asthana
- Sanna Seitsonen
- Sanni Lahdenperä
- Sano M.
- Sara López-García
- Sara López-García
- Sarah Pendergrass
- Saray Hevilla
- Sargurupremraj M.
- Sarnowski C.
- Sastre I.
- Satizabal C. L.
- Saykin A. J.
- Scamosci M.
- Scarmeas N.
- Scarpini E.
- Schellenberg G. D.
- Scheltens P.
- Scherbaum N.
- Scherer M.
- Schleutker J.
- Schmid M.
- Schmidt H.
- Schmidt R.
- Schneider A.
- Schneider J. A.
- Schneider L. S.
- Schott J. M.
- Schutzman J.
- Schürmann B.
- Scott Chasse
- Scott Small
- Seeley W. W.
- Seitsonen S.
- Sekhar H.
- Selbæk G.
- Selnes P.
- Seppo Vainio
- Seripa D.
- Serpente M.
- Serpi R.
- Serrano M.
- Seshadri S.
- Sevillano Z.
- Sha J.
- Shadrin A. A.
- Shahram Bahrami
- Shaikho E.
- Shameek Biswas
- Shaw C. E.
- Shcherban A.
- Shin J.
- Shofany J.
- Shulman J. M.
- Shuo Li
- Sid O'Bryant
- Siirtola H.
- Silvia Jesús
- Silvia Kochen
- Silvia Preckler
- Silvia Rodrigo
- Silvia Rodrigo-Herrero
- Simino J.
- Simon Cox
- Simon Lovestone
- Simona Andreoni
- Sims R.
- Sina Rüeger
- Sini Lähteenmäki
- Sinisalo J.
- Sipeky C.
- Sipilä K.
- Sipilä T. P.
- Siponen M.
- Sirkku Peltonen
- Sistonen T.
- Skrobot O.
- Slavé Petrovski
- Sleegers K.
- Slifer S.
- Sliz E.
- Small S.
- Smaoui N.
- Smith A. D.
- Smith A. G.
- Smith J.
- Smith J. P.
- Snijders G. J. L.
- Soininen H.
- Solfrizzi V.
- Solis P.
- Solomon A.
- Song Y. E.
- Sonnen J. A.
- Sorbi S.
- Sotolongo-Grau O.
- Soumitra Ghosh
- Spallazzi M.
- Spalletta G.
- Spina S.
- Spottke A.
- Squassina A.
- Stefan McDonough
- Stefan McDonough
- Stefan Teipel
- Stephanie Loomis
- Stephen J Glatt
- Stephen M Strittmatter
- Stephen Rich
- Stephen Todd
- Stern R. A.
- Steven E Arnold
- Steven Ferris
- Steven G Younkin
- Steven Greenberg
- Stevens A. B.
- Stordal E.
- Strandberg T.
- Strauss E.
- Strittmatter S. M.
- Struan F A Grant
- Stuart Pickering-Brown
- Ståhlbom A. K.
- Sultzer D.
- Suman Jayadev
- Suominen L.
- Susan Eaton
- Susan H Slifer
- Susan M McCurry
- Susan R Heckbert
- Susana Diego
- Susanna Lemmelä
- Sussams R.
- Suzanne Craft
- Sverre Bergh
- Swerdlow R. H.
- Sáez M. E.
- Sánchez-Arjona M. B.
- Sánchez-Valle R.
- Tai-He Xia
- Takalo M.
- Tamara Marín
- Tanzi R. E.
- Tarja Laitinen
- Tartan J. P.
- Taru Tukiainen
- Tasanen K.
- Taskinen M. -R.
- Tavia Evans
- Teea Salmi
- Teemu Natunen
- Teemu Niiranen
- Teemu Paajanen
- Teipel S.
- Teng E.
- Terhi Kilpi
- Terhi Ollila
- Tero Hiekkalinna
- Terttu Harju
- Tesí N.
- Teumer A.
- Thalamuthu A.
- Thomas A.
- Thomas C.
- Thomas D Bird
- Thomas Feulner
- Thomas G Beach
- Thomas J Fairchild
- Thomas J Grabowski
- Thomas J Montine
- Thomas S Wingo
- Thomas T.
- Thomas Wisniewski
- Thomassen J. Q.
- Thonberg H.
- Tienari P.
- Tiffany F Kautz
- Tiina Laatikainen
- Tiinamaija Tuomi
- Tilson J. L.
- Tim Becker
- Tim Behrens
- Tim Lu
- Timo Blomster
- Timo P Sipilä
- Timo Strandberg
- Timothy Hohman
- Timothy Hughes
- Tin A.
- Todd S.
- Tomas Paus
- Tomi Mäkelä
- Toso C. R.
- Tosto G.
- Traykov L.
- Tremolizzo L.
- Trojanowski J. Q.
- Troncoso J. C.
- Trung Nguyen
- Tsai E.
- Tsolaki A.
- Tsolaki M.
- Tsuang D. W.
- Tsuo K.
- Tucker-Drob E.
- Tukiainen T.
- Tuomi T.
- Tuomilehto J.
- Tuomo Kiiskinen
- Tuomo Mantere
- Tuomo Meretoja
- Tuovila O.
- Turpeinen M.
- Turton J.
- Turunen J. A.
- Tushar Bhangale
- Tuula Salo
- Tuuli Sistonen
- Tybjærg-Hansen A.
- Tzourio C.
- Tárraga L.
- Uitterlinden A.
- Ulla Palotie
- Ullgren A.
- Ulstein I.
- Ulvi Gursoy
- Uphill J.
- Urho Kujala
- Usiskin K.
- Uusitalo H.
- Uusitalo-Järvinen H.
- Vacca A.
- Vaclav Matoska
- Vainio S.
- Valentina Ciullo
- Valeria Cores
- Valero S.
- Valladares O.
- Valladares O.
- Valory Pavlik
- Valtteri Julkunen
- van Adelsberg J.
- Van Deerlin V. M.
- van den Bussche H.
- van der Flier W. M.
- van der Lee S. J.
- van der Lugt A.
- van Duijn C. M.
- van Eldik L. J.
- van Lent D. M.
- van Rooij J.
- van Swieten J.
- Vance J.
- Vandenberghe R.
- Vardarajan B. N.
- Vardy E.
- Vargas L.
- Vassar R.
- Veikko Salomaa
- Veli-Matti Kosma
- Venkat Subramaniam Rathinakannan
- Verhey F.
- Vesa Aaltonen
- Vicente M. P.
- Victor W Henderson
- Victoria Fernandez-Hernandez
- Victoria Perez
- Victoriana Martínez
- Vidal J. -S.
- Vigo-Ortega R.
- Vilas R. H.
- Vinay Mehta
- Vincent Deramecourt
- Vincent Deramerourt
- Vincent Llorens
- Vinters H. V.
- Virolainen P.
- Vivancos L.
- Vivianna M Van Deerlin
- Vogelgsang J.
- Vojinovic D.
- Vonsattel J. -P.
- Voutilainen M.
- Vuokko Anttonen
- Vyhnalek M.
- Wadhawan S.
- Wagner M.
- Wallon D.
- Wang C.
- Wang L. -S.
- Wang R.
- Wang Y.
- Warden D.
- Waring J.
- Waring J.
- Warner N.
- Warren J. D.
- Waterworth D.
- Wayne C McCormick
- Wayne W Poon
- Weber H.
- Wei Gu
- Wei Zhou
- Weinhold L.
- Weinstein G.
- Weintraub S.
- Welsh-Bohmer K. A.
- Whelan C.
- Whitehead P. L.
- Wichmann H. -E.
- Wigmore E.
- Wijsman E. M.
- Wilcock G.
- Wilhelmsen K. C.
- Will S Bush
- William Kremen
- William Nash
- William W Seeley
- Williams A.
- Williams B.
- Williams D.
- Williams J.
- Williamson J.
- Wilms H.
- Wiltfang J.
- Windle G.
- Wingo T. S.
- Wisniewski T.
- Wittfeld K.
- Woltjer R. L.
- Wong R.
- Woods B.
- Woon M.
- Wright C. B.
- Wu C. -K.
- Wu Y.
- Xia T. -H.
- Xing Chen
- Xinli Hu
- Xiongwei Zhu
- Xu E.
- Xu F.
- Xuan Liu
- Yanbing Wang
- Yanek L.
- Yang Q.
- Yang Y.
- Yannakoulia M.
- Yaqub A.
- Yasaman Saba
- Yash Patel
- Yeunjoo E Song
- Yi Zhao
- Ying Wu
- Yoav Ben-Shlomo
- Yogen Patel
- Younkin S. G.
- Yu C. -E.
- Yu L.
- Yuanchao Zhang
- Yuk Yee Leung
- Yunfeng Huang
- Yunju Yang
- Zare H.
- Zdenka Pausova
- Zhang X.
- Zhang Y.
- Zhao Y.
- Zhao Y.
- Zhou W.
- Zhu C.
- Zhu X.
- Ziemann A.
- Zoia C. P.
- Zompo M. D.
- Zulaica M.
- Zulma Sevillano
- Álvarez V.
- Åsa Hedman
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
Characterization of the genetic landscape of Alzheimer’s disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/‘proxy’ AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele