53 research outputs found
Neanderthal selective hunting of reindeer? The case study of Abri du Maras (south-eastern France)
Fieldwork was supported by the Regional Office of Archaeology RhĂŽne-Alpes, the French Ministry of Culture and Communication and the ArdĂšche Department through several scientific programs. M.G.Chacon, F. Rivals and E. AlluĂ© research are funded by âCERCA Programme/Generalitat de Catalunyaâ. Thanks to Jean-Jacques Hublin, Annabell Reiner and Steven Steinbrenner from the Max Planck Institute (MPI-EVA) for analytical support (isotope analysis). We are grateful to the two anonymous reviewers for their constructive remarks on this manuscript. The English manuscript was edited by L. Byrne, an official translator and native English speaker.Peer reviewedPostprin
Lâinsediamento a bifacciali di Guado San Nicola (Monteroduni, Molise, Italia)
La monografia rappresenta un compendio di lavori specialistici sul sito paleolitico di Guado San Nicola a Monteroduni (Molise, Italia), oggetto di ricerche sistematiche ed indagini interdisciplinari inaugurate nellâarea a partire dal 2000 dall'UniversitĂ degli Studi di Ferrara. Il sito, ascrivibile al MIS 10/11, costituisce un tassello importante nellâambito della ricostruzione del quadro del popolamento umano della penisola italiana e dellâintero bacino del Mediterraneo, alla luce delle considerazioni crono-stratigrafiche, della ricchezza della documentazione e della presenza di elementi innovativi dal punto di vista culturale quali la padronanza del metodo Levallois e lâuso di percussori in palchi di cervo
Dating the Homo erectus bearing travertine from KocabaĆ (Denizli, Turkey) at at least 1.1 Ma
Since its discovery within a travertine quarry, the fragmentary cranium of the only known Turkish Homo erectus, the KocabaĆ hominid, has led to conflicting biochronological estimations. First estimated to be ~500ka old, the partial skull presents a combination of archaic and evolved features that puts it as an intermediate specimen between the Dmanisi fossils (Homo georgicus) and the Chinese Zhoukoudian skulls (Homo erectus) respectively dated to 1.8 to ~0.8Ma. Here we present a multidisciplinary study combining sedimentological, paleontological and paleoanthropological observations together with cosmogenic nuclide concentration and paleomagnetic measurements to provide an absolute chronological framework for the Upper fossiliferous Travertine unit where the KocabaĆ hominid and fauna were discovered. The 26Al/10Be burial ages determined on pebbles from conglomeratic levels framing the Upper fossiliferous Travertine unit, which exhibits an inverse polarity, constrains its deposition to before the Cobb Mountain sub-chron, that is between 1.22 and ~1.5Ma. The alternative match of the normal polarity recorded above the travertine with the Jaramillo subchron (lower limit 1.07 Ma) may also be marginally compatible with cosmogenic nuclides interpretation, thus the proposed minimum age of 1.1 Ma for the end of massive travertine deposition. The actual age of the fossils is likely to be in the 1.1-1.3 Ma range. This absolute date is in close agreement with the paleoanthropological conclusions based on morphometric comparisons implying that KocabaĆ hominid belongs to the Homo erectus s.l. group that includes Chinese and African fossils, and is different from Middle and Upper Pleistocene specimens. Furthermore, this date is confirmed by the large mammal assemblage, typical of the late Villafranchian. Because it attests to the antiquity of human occupation of the Anatolian Peninsula and one of the waves of settlements out of Africa, this work challenges the current knowledge of the Homo erectus dispersal over Eurasia. © 2014 The Authors
Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling
Many cellular processes including apoptosis, autophagy, translation, energy metabolism, and inflammation are controlled by the mammalian target of rapamycin (mTOR) kinase and the endoplasmic reticulum (ER) stress pathway, also known as the unfolded protein response (UPR). Although both of these signaling nodes have attracted wide attention in fundamental cell biology and drug discovery, crosstalk between the two pathways has emerged only very recently. mTOR complex 1 (mTORC1) operates both upstream and downstream of ER stress signals, which can either enhance or antagonize the anabolic output of mTORC1. Upon prolonged ER stress, mTORC1 contributes to apoptotic signaling by suppressing the survival kinase Akt through feedback inhibition. Likewise, chronic ER stress obstructs activation of Akt by mTOR complex 2. This review surveys our knowledge of mTOR-ER stress intersections and highlights potential therapeutic implications
La faune de la fin du PlĂ©istocĂšne moyen de la dĂ©charge dâAubais (Gard, France)
Résumé
Il y a une vingtaine dâannĂ©es, des dents de mammouths ont Ă©tĂ© retrouvĂ©es dans les dĂ©blais de la dĂ©charge de la commune dâAubais (Gard, Sud-Est de la France). Des opĂ©rations de fouille de sauvetage, de tri et de tamisage ont par la suite Ă©tĂ© menĂ©es et ont permis dâidentifier la prĂ©sence de 19 taxons de vertĂ©brĂ©s continentaux. Les carnivores dominent (n=10), suivis par les herbivores (n=5), les oiseaux (n=1) et les lĂ©poridĂ©s (n=2) dont les restes sont les plus abondants. Aucun reste de micromammifĂšres nâa en revanche Ă©tĂ© retrouvĂ©. Les observations sĂ©dimentologiques croisĂ©es aux donnĂ©es gĂ©ologiques locales permettent dâaffirmer lâhomogĂ©nĂ©itĂ© de la faune piĂ©gĂ©e dans une ancienne doline creusĂ©e dans des niveaux burdigaliens. Les restes osseux Ă©taient Ă lâorigine en bon Ă©tat de conservation mais ont Ă©tĂ© fragmentĂ©s lors de leur extraction par des engins de terrassement (fracturation et griffures dâengins). Le type dâextraction du sĂ©diment Ă lâorigine de ces dĂ©blais nâa pas permis de procĂ©der Ă une Ă©tude taphonomique. Les diffĂ©rentes Ă©tudes fauniques permettent de positionner chronologiquement le gisement au cours du stade isotopique 6. Aucune trace dâactivitĂ©s humaines et carnivores nâa Ă©tĂ© dĂ©tectĂ©e et la faune de la dĂ©charge dâAubais permet de mieux comprendre lâenvironnement dans lequel Ă©voluaient les groupes humains de la rĂ©gion Ă fin du PlĂ©istocĂšne moyen.Abstract
Twenty years ago, mammoth teeth were discovered in Aubais landfill (Gard, Southeastern France). Salvage excavations were subsequently conducted and the sediment has been sifted and screened. Therefore, 19 continental vertebrate species have been identified. Carnivores species are dominant (n=10) followed by the herbivorous (n=5), birds (n=1) and leporids (n=2) which are the most abundant. In contrast, no micromammal remains were found. The analysis of the sediments and the local geological data permit to indicate that this fauna is homogeneous and has been trapped in an oldest sinkhole opened in the Burdigalian. The faunal remains were well preserved initially but they were fragmented during their extraction by earth-moving machine (breakage, scratches). Consequently, it was not possible to study the taphonomical processes. The paleontological study allows us to chronologically relate the deposit to the marine isotopic stage 6. Although no indication of human activities has been detected, the Aubais fauna provides a better understanding of the local environment of human groups during the late Middle Pleistocene
REPRISES PLIO-PLEISTOCENES DU PALEOKARST QUERCINOIS
National audienceL'investigation du paléokarst du Sud-Quercy (France) a révélé en de nombreux points une reprise d'érosion et remblaiement superficiels de la plateforme karstique jurassique, succédant à celle plus généralisée du PaléogÚne. Cette reprise est marquée par la présence de fossiles, notamment de grands et petits mammifÚres. La note dresse un inventaire de ces localités dans leur contexte géologique et de leurs restes fossiles. Leurs ùges sont distribués depuis le PliocÚne supérieur jusqu'à l'HolocÚne et principalement dans la période du PléistocÚne moyen et supérieur (de 0,5 à 0,1 Ma)
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