28 research outputs found
Low dimensional strongly perfect lattices. I: The 12-dimensional case
It is shown that the Coxeter-Todd lattice is the unique strongly perfect
lattice in dimension 12
Construction of spherical cubature formulas using lattices
We construct cubature formulas on spheres supported by homothetic images of
shells in some Euclidian lattices. Our analysis of these cubature formulas uses
results from the theory of modular forms. Examples are worked out on the sphere
of dimension n-1 for n=4, 8, 12, 14, 16, 20, 23, and 24, and the sizes of the
cubature formulas we obtain are compared with the lower bounds given by Linear
Programming
The genetic architecture of the human cerebral cortex
The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson's disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder