107 research outputs found

    Application of a mode-locked fiber laser for highly time resolved broadband absorption spectroscopy and laser-assisted breakdown on micro-plasmas

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    Cataloged from PDF version of article.Absorption spectroscopy is known to be a powerful tool to gain spatially and temporally resolved information on excited and reactive species in a plasma discharge. Furthermore, the interaction of the discharge with short intense laser pulses can trigger the ignition and the transition into other transient states of the plasma. In this context laser-assisted 'pump-probe' experiments involving simultaneously generated supercontinuum radiation yield highly temporally resolved and spatially well-defined information on the transient phenomena. In this paper we demonstrate the possibility for 'pump-probe' experiments by initiating breakdown on a picosecond time scale ('pump') with a high-power beam and measuring the broadband absorption with the simultaneously provided supercontinuum ('probe'). Since both pulses are generated from the same mode-locked master oscillator, they have a strong level of synchronization

    Compulsory admissions of patients with mental disorders : State of the art on ethical and legislative aspects in 40 European countries

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    Copyright: This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of MedicineBACKGROUND.: Compulsory admission procedures of patients with mental disorders vary between countries in Europe. The Ethics Committee of the European Psychiatric Association (EPA) launched a survey on involuntary admission procedures of patients with mental disorders in 40 countries to gather information from all National Psychiatric Associations that are members of the EPA to develop recommendations for improving involuntary admission processes and promote voluntary care. METHODS.: The survey focused on legislation of involuntary admissions and key actors involved in the admission procedure as well as most common reasons for involuntary admissions. RESULTS.: We analyzed the survey categorical data in themes, which highlight that both medical and legal actors are involved in involuntary admission procedures. CONCLUSIONS.: We conclude that legal reasons for compulsory admission should be reworded in order to remove stigmatization of the patient, that raising awareness about involuntary admission procedures and patient rights with both patients and family advocacy groups is paramount, that communication about procedures should be widely available in lay-language for the general population, and that training sessions and guidance should be available for legal and medical practitioners. Finally, people working in the field need to be constantly aware about the ethical challenges surrounding compulsory admissions.Peer reviewe

    Boron Stress Responsive MicroRNAs and Their Targets in Barley

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    Boron stress is an environmental factor affecting plant development and production. Recently, microRNAs (miRNAs) have been found to be involved in several plant processes such as growth regulation and stress responses. In this study, miRNAs associated with boron stress were identified and characterized in barley. miRNA profiles were also comparatively analyzed between root and leave samples. A total of 31 known and 3 new miRNAs were identified in barley; 25 of them were found to respond to boron treatment. Several miRNAs were expressed in a tissue specific manner; for example, miR156d, miR171a, miR397, and miR444a were only detected in leaves. Additionally, a total of 934 barley transcripts were found to be specifically targeted and degraded by miRNAs. In silico analysis of miRNA target genes demonstrated that many miRNA targets are conserved transcription factors such as Squamosa promoter-binding protein, Auxin response factor (ARF), and the MYB transcription factor family. A majority of these targets were responsible for plant growth and response to environmental changes. We also propose that some of the miRNAs in barley such as miRNA408 might play critical roles against boron exposure. In conclusion, barley may use several pathways and cellular processes targeted by miRNAs to cope with boron stress

    The Phrenic Component of Acute Schizophrenia – A Name and Its Physiological Reality

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    Decreased heart rate variability (HRV) was shown for unmedicated patients with schizophrenia and their first-degree relatives, implying genetic associations. This is known to be an important risk factor for increased cardiac mortality in other diseases. The interaction of cardio-respiratory function and respiratory physiology has never been investigated in the disease although it might be closely related to the pattern of autonomic dysfunction. We hypothesized that increased breathing rates and reduced cardio-respiratory coupling in patients with acute schizophrenia would be associated with low vagal function. We assessed variability of breathing rates and depth, HRV and cardio-respiratory coupling in patients, their first-degree relatives and controls at rest. Control subjects were investigated a second time by means of a stress task to identify stress-related changes of cardio-respiratory function. A total of 73 subjects were investigated, consisting of 23 unmedicated patients, 20 healthy, first-degree relatives and 30 control subjects matched for age, gender, smoking and physical fitness. The LifeShirt®, a multi-function ambulatory device, was used for data recording (30 minutes). Patients breathe significantly faster (p<.001) and shallower (p<.001) than controls most pronouncedly during exhalation. Patients' breathing is characterized by a significantly increased amount of middle- (p<.001), high- (p<.001), and very high frequency fluctuations (p<.001). These measures correlated positively with positive symptoms as assessed by the PANSS scale (e.g., middle frequency: r = 521; p<.01). Cardio-respiratory coupling was reduced in patients only, while HRV was decreased in patients and healthy relatives in comparison to controls. Respiratory alterations might reflect arousal in acutely ill patients, which is supported by comparable physiological changes in healthy subjects during stress. Future research needs to further investigate these findings with respect to their physiological consequences for patients. These results are invaluable for researchers studying changes of biological signals prone to the influence of breathing rate and rhythm (e.g., functional imaging)

    Compulsory admissions of patients with mental disorders : State of the art on ethical and legislative aspects in 40 European countries

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    Background. Compulsory admission procedures of patients with mental disorders vary between countries in Europe. The Ethics Committee of the European Psychiatric Association (EPA) launched a survey on involuntary admission procedures of patients with mental disorders in 40 countries to gather information from all National Psychiatric Associations that are members of the EPA to develop recommendations for improving involuntary admission processes and promote voluntary care. Methods. The survey focused on legislation of involuntary admissions and key actors involved in the admission procedure as well as most common reasons for involuntary admissions. Results. We analyzed the survey categorical data in themes, which highlight that both medical and legal actors are involved in involuntary admission procedures. Conclusions. We conclude that legal reasons for compulsory admission should be reworded in order to remove stigmatization of the patient, that raising awareness about involuntary admission procedures and patient rights with both patients and family advocacy groups is paramount, that communication about procedures should be widely available in lay-language for the general population, and that training sessions and guidance should be available for legal and medical practitioners. Finally, people working in the field need to be constantly aware about the ethical challenges surrounding compulsory admissions.Peer reviewe

    The Effect of Socioeconomic and Behavioral Factors on Childhood Stunting in Janamora District, Ethiopia

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    Yibrie Azmeraw,1 Temesgen Yihunie Akalu,2 Moges Boke,3 Kassahun Gelaye2 1Janamora District Health Office, North Gondar Zone, Ethiopia; 2Department of Epidemiology, Institute of Public Health, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia; 3Department of Reproductive Health, Institute of Public Health, College of Medicine and Health Science, University of Gondar, Gondar, EthiopiaCorrespondence: Moges Boke Tel +251 926114631Email [email protected]: Globally in 2016, 22.9% of under-five children were stunted. In Ethiopia, the current reduction rate was 2.8%, which was far from the global nutritional target of 2025. However, evidence on the prevalence of stunting and its associated factors in Janamora district was very limited. Therefore, this study aimed to determine the prevalence of stunting and to identify the risk factors among 6&ndash; 59 months children in Janamora district.Methods: A community-based cross-sectional study was conducted in Janamora district from February to March 2020. A multistage cluster sampling technique was used to select 845 study participants. Data were collected using an interviewer-administered technique from caregivers, and anthropometric measurements were taken from the child. An adjusted odds ratio and a P-value &lt; 0.05 were used to declare statistical significance.Results: The prevalence of stunting in this study was 44.9% (95% CI: 41.5, 48.4). The following conditions were significantly affected stunting: age of child 6&ndash; 11 months (AOR=2.5 (1.18&ndash; 5.29)), 12&ndash; 24 months (AOR=3.38 (1.95&ndash; 5.88)), 24&ndash; 35 months (AOR=2.33 (1.35,4.01)), wealth status: poorest (AOR=2.79 (1.66,4.68)), poor (AOR=2.15 (1.29,3.57)), medium (AOR=2.09 (1.25,3.49)), good knowledge of mothers/caregivers on handwashing: (AOR = 0.64 (0.43,0.92)), presence of diarrhea: (AOR = 1.9 (1.23,2.95)), start complementary feeding at six months: (AOR=0.58 (0.39,0.88)), start complementary feeding before six months: (AOR=1.58 (1.07,2.34)), and large family size: (AOR=2.33 (1.70,3.21)).Conclusion: In this study, the prevalence of stunting was high. Being a younger child, living with a large family size, low wealth status, starting complementary feeding before and at 6-months, and diarrhea were provoking factors for stunting. On the other hand, good knowledge of mothers on handwashing during the critical time was associated with a low risk of stunting. Therefore, the nutrition programs need to give focus activities that enhance caregiver&rsquo;s handwashing knowledge at the critical time and to start complementary feeding at the appropriate age.Keywords: prevalence, stunting, 6 to 59 months, Janamora distric

    Hypertorphie des végétations adénoïdes aspects épidémiologiques, diagnostiques et thérapeutiques (étude à propos de 389 cas)

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    No Abstract Available J. Rech. Sci. Univ. Lomé (Togo) 2002, 6(2) : 199-20

    Effects of farm type on food production, landscape openness, grassland biodiversity, and greenhouse gas emissions in mixed agricultural-forestry regions

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    Context: The global demand for food is expected to continue increasing for decades, which may drive both agricultural expansion and intensification. The associated environmental impacts are potentially considerable but will depend on how the agricultural sector develops. Currently, there are contrasting regional developments in agriculture; expansion and/or intensification in some regions and abandonment in others, as well as changes in the type of farming. However, the environmental consequences of changes in farm type are not well understood.Objective: We have evaluated the impacts of farm type on food production and three key environmental variables & mdash;landscape openness, grassland biodiversity and greenhouse gas (GHG) emissions & mdash;in three marginal agricultural regions in Sweden.Methods: We do this by first dividing the population of farms in each region into types, based on their land-use and livestock holdings using an innovative clustering method. Thereafter we analysed changes in production activities for farm types over time and evaluated the environmental and food-production impacts, where landscape openness is quantified using a novel indicator.Results and conclusion: Our results show that there is not one single farm type that would simultaneously maximize food production, grassland biodiversity, and landscape openness, whilst minimizing GHG emissions. However, there exists considerable potential to manage the trade-offs between food production and these environmental variables. For example, by reducing land use for dairying and instead increasing both cropping for food production and extensive livestock grazing to maintain landscape openness and biodiversity-rich semi natural pastures, it would keep food production at similar levels.Significance: Our farm typology allows us to assess the multifunctionality of farming, by relating contrasting production activities to multiple ecosystem services, grassland biodiversity and GHG emissions for informing policy towards more sustainable agriculture. We have demonstrated this with examples under Swedish conditions, but it should to a large extent also be applicable for other countries
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