108 research outputs found

    Women Judges: A Preface to Their History

    Get PDF
    A special concern of this paper is the presence of women at the top of the judicial hierarchy. Understanding why women are (or are not) able to move up the opportunity structure requires data on the number and percentage of women on these prestigious courts. Appendix I provides a list arranged by state of every woman who has served on a prestigious court. The following examines the relationship between the increase in the number of positions in the courts and the presence of women. The next section examines the steps in the opportunity structure to prestigious judgeships, and the gatekeeping devices which control the movement of individuals from one position to another higher one

    Women Judges: A Preface to Their History

    Get PDF
    A special concern of this paper is the presence of women at the top of the judicial hierarchy. Understanding why women are (or are not) able to move up the opportunity structure requires data on the number and percentage of women on these prestigious courts. Appendix I provides a list arranged by state of every woman who has served on a prestigious court. The following examines the relationship between the increase in the number of positions in the courts and the presence of women. The next section examines the steps in the opportunity structure to prestigious judgeships, and the gatekeeping devices which control the movement of individuals from one position to another higher one

    Verbal Communication Skills Requirements for Information Systems Professionals

    Get PDF
    The role of information systems (IS) professionals in organizations has changed through the years, from one who works mostly with technically oriented peers, to one who spends a significant amount of time interacting with people who are involved in the functional areas of the organization. In many organizations, IS professionals are assigned permanently to the user area and they are expected to not only be technically competent, but also be competent in the user\u27s area. This move of IS professionals to the functional areas necessitates that they communicate more with the functional users whose IS needs they are fulfilling. The users, on the other hand, are also required to interact and communicate more with the IS people. With the move toward distributed IS, users are becoming more involved in the specification, design and sometimes even construction of their own systems. It is therefore imperative that analysts and users be able to communicate with each other unequivocally, so that the systems are specified and developed properly. This research investigated the verbal communication skills requirements for IS practicing professionals and new university graduates. A survey was used for data collection. It was sent to IS professionals in several large organizations, that represented the industry in general. A nearly perfect response rate was achieved. The findings are useful for both IS professionals and university programs. Organizations can use the findings to identify areas of weaknesses in the skills of their IS personnel and eliminate them with continuing education. Universities can use the findings to identify skills that they may not be currently emphasizing in their curricula and make necessary adjustments

    Intercomparison of MODIS Albedo Retrievals and In Situ Measurements Across the Global FLUXNET Network

    Get PDF
    Surface albedo is a key parameter in the Earth's energy balance since it affects the amount of solar radiation directly absorbed at the planet surface. Its variability in time and space can be globally retrieved through the use of remote sensing products. To evaluate and improve the quality of satellite retrievals, careful intercomparisons with in situ measurements of surface albedo are crucial. For this purpose we compared MODIS albedo retrievals with surface measurements taken at 53 FLUXNET sites that met strict conditions of land cover homogeneity. A good agreement between mean yearly values of satellite retrievals and in situ measurements was found (R(exp 2)= 0.82). The mismatch is correlated to the spatial heterogeneity of surface albedo, stressing the relevance of land cover homogeneity when comparing point to pixel data. When the seasonal patterns of MODIS albedo is considered for different plant functional types, the match with surface observation is extremely good at all forest sites. On the contrary, in non-forest sites satellite retrievals underestimate in situ measurements across the seasonal cycle. The mismatch observed at grasslands and croplands sites is likely due to the extreme fragmentation of these landscapes, as confirmed by geostatistical attributes derived from high resolution scenes

    Ethnic differences in DNA methyltransferases expression in patients with systemic lupus erythematosus

    Get PDF
    Systemic lupus erythematous (SLE) is a systemic autoimmune inflammatory disease with both genetic and epigenetic etiologies. Evidence suggests that deregulation of specific genes through epigenetic mechanisms may be a contributing factor to SLE pathology. There is increasing evidence that DNA methyltransferase activity may be involved. This study demonstrated modulation in expression of DNA methyltransferases (DNMTs) according to ethnicity in patients diagnosed with SLE. Furthermore, differential expression in one of the DNMTs was found in a subset of lupus patients on dehydroepiandrosterone (DHEA) therapy. Real-time PCR analyses of DNMT1, DNMT3A and DNMT3B in peripheral blood mononuclear cells from a cohort of African American and European American lupus and non-lupus women were conducted. Also, global DNA methylation was assessed using the MethylFlash.sup.TM methylated quantification colorimetric assay. These findings suggest that epigenetic changes may play a critical role in the manifestations of the disease observed among ethnic groups, particularly African American women who often have a higher incidence of lupus. DHEA therapy effects on DNMT3A expression in AA women warrant further investigation in a larger population

    Genome-Wide Association Study Identifies Genetic Loci Associated with Iron Deficiency

    Get PDF
    The existence of multiple inherited disorders of iron metabolism in man, rodents and other vertebrates suggests genetic contributions to iron deficiency. To identify new genomic locations associated with iron deficiency, a genome-wide association study (GWAS) was performed using DNA collected from white men aged ≥25 y and women ≥50 y in the Hemochromatosis and Iron Overload Screening (HEIRS) Study with serum ferritin (SF) ≤ 12 µg/L (cases) and iron replete controls (SF>100 µg/L in men, SF>50 µg/L in women). Regression analysis was used to examine the association between case-control status (336 cases, 343 controls) and quantitative serum iron measures and 331,060 single nucleotide polymorphism (SNP) genotypes, with replication analyses performed in a sample of 71 cases and 161 controls from a population of white male and female veterans screened at a US Veterans Affairs (VA) medical center. Five SNPs identified in the GWAS met genome-wide statistical significance for association with at least one iron measure, rs2698530 on chr. 2p14; rs3811647 on chr. 3q22, a known SNP in the transferrin (TF) gene region; rs1800562 on chr. 6p22, the C282Y mutation in the HFE gene; rs7787204 on chr. 7p21; and rs987710 on chr. 22q11 (GWAS observed P<1.51×10−7 for all). An association between total iron binding capacity and SNP rs3811647 in the TF gene (GWAS observed P = 7.0×10−9, corrected P = 0.012) was replicated within the VA samples (observed P = 0.012). Associations with the C282Y mutation in the HFE gene also were replicated. The joint analysis of the HEIRS and VA samples revealed strong associations between rs2698530 on chr. 2p14 and iron status outcomes. These results confirm a previously-described TF polymorphism and implicate one potential new locus as a target for gene identification

    Online Stakeholder Interactions in the Early Stage of a Megaproject

    Get PDF
    The purpose of this paper is to examine the network structure of online stakeholder discussions in the planning stage of a UK public mega project, High Speed Rail. By providing new rail connections between London, Birmingham and Manchester, this project is highly complex as it is embedded in a network of stakeholder relationships that may support or oppose the project. Data drawn from Twitter was analyzed using Social Network Analysis and inductive analysis of user profiles and content. Findings indicate that the majority of online stakeholders oppose the project and form stable clusters. Larger clusters within this network may attempt to deploy power directly in the form of a manipulation strategy while smaller clusters may seek to ally themselves with more powerful groups, a pathway strategy. Overall, the methodology is a useful complement to existing methods and may provide real time insights into the complex, evolving discussions around mega projects

    A standardized terminology for describing reproductive development in fishes

    Get PDF
    19 páginas, 12 figuras, 3 tablas.-- Open access journalAs the number of fish reproduction studies has proliferated, so has the number of gonadal classification schemes and terms. This has made it difficult for both scientists and resource managers to communicate and for comparisons to be made among studies.We propose the adoption of a simple, universal terminology for the phases in the reproductive cycle, which can be applied to all male and female elasmobranch and teleost fishes. These phases were chosen because they define key milestones in the reproductive cycle; the phases include immature, developing, spawning capable, regressing, and regenerating. Although the temporal sequence of events during gamete development in each phase may vary among species, each phase has specific histological and physiological markers and is conceptually universal. The immature phase can occur only once. The developing phase signals entry into the gonadotropin-dependent stage of oogenesis and spermatogenesis and ultimately results in gonadal growth. The spawning capable phase includes (1) those fish with gamete development that is sufficiently advanced to allow for spawning within the current reproductive cycle and (2) batch-spawning females that show signs of previous spawns (i.e., postovulatory follicle complex) and that are also capable of additional spawns during the current cycle. Within the spawning capable phase, an actively spawning subphase is defined that corresponds to hydration and ovulation in females and spermiation in males. The regressing phase indicates completion of the reproductive cycle and, for many fish, completion of the spawning season. Fish in the regenerating phase are sexually mature but reproductively inactive. Species-specific histological criteria or classes can be incorporated within each of the universal phases, allowing for more specific divisions (subphases) while preserving the overall reproductive terminology for comparative purposes. This terminology can easily be modified for fishes with alternate reproductive strategies, such as hermaphrodites (addition of a transition phase) and livebearers (addition of a gestation phase)Fish Reproduction and Fisheries (FRESH; European Cooperation in Science and Technology Action FA0601) and theWest Palm Beach Fishing Club (Florida) provided funding for the gonadal histology workshops where this terminology was developed and refined. Additionally, we thank FRESH for travel and publication fundsPeer reviewe
    • …
    corecore