112 research outputs found

    Symptôme… σύμπτωμα... sumptoma

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    del síntoma y de sus dimensiones etimológica, teórica y clínica. La primera dimensión aborda su etimología griega y latina; la segunda trata el síntoma en la enseñanza freudiana, desde el descubrimiento del inconsciente y su lazo con la estructura del sujeto y, por último, da cuenta del acercamiento lacaniano al síntoma y de sus mayores modificaciones, que han llevado a proponer la existencia de un anudamiento borromeo de lo real, lo simbólico y lo imaginario. A partir de la clínica del caso Joyce se propone un cuestionamiento de la función del sinthome como anudamiento singular que introduce creaciones particulares en la renovación del lazo social. Symptôme… sύmptwma..sumptoma L’auteur avance une étude du symptôme et de ses dimensions étymologique, théorique et clinique. La première dimension déploie son étymologie grecque et latine. La deuxième aborde le symptôme dans l’enseignement freudien dès la découverte de l’inconscient et de son lien à la structure du sujet. Finalement, compte est rendu de l’approche lacanienne du symptôme et des remaniements majeurs qui le conduisent à poser l’existence du nouage borroméen du réel, du symbolique, de l’imaginaire. À partir de la clinique du cas de Joyce, un questionnement sur la fonction du sinthome comme nouage singulier mettant en jeu des créations singulières qui participent à un renouveau du lien social est proposé. Symptôme… sύmptwma...sumptoma This article propounds a study about symptoms and their etymological, theoretical, and clinical dimensions. The first dimension concerns Greek and Latin etymology. The second approaches Freudian teachings based on the discovery of the unconscious and its relationship with the subject’s structure. The third accounts for the Lacanian approach to symptoms and the major overhauls that have led to the proposal of the existence of the Borromean binding of the real, the symbolic, and the imaginary. The clinical case of Joyce denotes an inquiry into the sinthome’s function as a singular knot that introduces particular creations in the renewal of social ties

    Histoire et modélisation des dynamiques socio-environnementales Holocènes des paysages fluviaux de la côte d'Azur

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    History and modelling of the socio-environmental dynamics of the fluvial landscapes of Côte-d'Azur (France) during the Holocene A research program was initiated in 2006 in order to reconstruct the evolution of the coastal hydrosystems of the rivers Argens (Var), Loup, Cagne and Malvan (Alpes-Maritimes) during the Holocene. The paper presents the archaeological and palaeoenvironmental data and the me thods used to apprehend the effects of the landscapes mobility over settlement patterns, and the impact of human occupation over the ecosystems.Un programme de recherches a été initié en 2006 afin de retracer l'évolution des hydrosystèmes côtiers de l'Argens (Var), du Lou p, de la Cagne et du Malvan (Alpes-Maritimes) au cours de l'Holocène. L'article présente les données archéologiques et paléoenvironnementales mobilisées et les méthodes mises en œuvre pour appréhender les répercussions de la mobilité de ces paysages sur le peuplement et l'impact de l'occupation humaine sur les écosystème

    Open versus laparoscopically-assisted oesophagectomy for cancer: a multicentre randomised controlled phase III trial - the MIRO trial

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    <p>Abstract</p> <p>Background</p> <p>Open transthoracic oesophagectomy is the standard treatment for infracarinal resectable oesophageal carcinomas, although it is associated with high mortality and morbidity rates of 2 to 10% and 30 to 50%, respectively, for both the abdominal and thoracic approaches. The worldwide popularity of laparoscopic techniques is based on promising results, including lower postoperative morbidity rates, which are related to the reduced postoperative trauma. We hypothesise that the laparoscopic abdominal approach (laparoscopic gastric mobilisation) in oesophageal cancer surgery will decrease the major postoperative complication rate due to the reduced surgical trauma.</p> <p>Methods/Design</p> <p>The MIRO trial is an open, controlled, prospective, randomised multicentre phase III trial. Patients in study arm A will receive laparoscopic-assisted oesophagectomy, i.e., a transthoracic oesophagectomy with two-field lymphadenectomy and laparoscopic gastric mobilisation. Patients in study arm B will receive the same procedure, but with the conventional open abdominal approach. The primary objective of the study is to evaluate the major postoperative 30-day morbidity. Secondary objectives are to assess the overall 30-day morbidity, 30-day mortality, 30-day pulmonary morbidity, disease-free survival, overall survival as well as quality of life and to perform medico-economic analysis. A total of 200 patients will be enrolled, and two safety analyses will be performed using 25 and 50 patients included in arm A.</p> <p>Discussion</p> <p>Postoperative morbidity remains high after oesophageal cancer surgery, especially due to major pulmonary complications, which are responsible for 50% of the postoperative deaths. This study represents the first randomised controlled phase III trial to evaluate the benefits of the minimally invasive approach with respect to the postoperative course and oncological outcomes in oesophageal cancer surgery.</p> <p>Trial Registration</p> <p><a href="http://www.clinicaltrials.gov/ct2/show/NCT00937456">NCT00937456</a> (ClinicalTrials.gov)</p

    Observation of gravitational waves from the coalescence of a 2.5−4.5 M⊙ compact object and a neutron star

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    Search for gravitational-lensing signatures in the full third observing run of the LIGO-Virgo network

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    Gravitational lensing by massive objects along the line of sight to the source causes distortions of gravitational wave-signals; such distortions may reveal information about fundamental physics, cosmology and astrophysics. In this work, we have extended the search for lensing signatures to all binary black hole events from the third observing run of the LIGO--Virgo network. We search for repeated signals from strong lensing by 1) performing targeted searches for subthreshold signals, 2) calculating the degree of overlap amongst the intrinsic parameters and sky location of pairs of signals, 3) comparing the similarities of the spectrograms amongst pairs of signals, and 4) performing dual-signal Bayesian analysis that takes into account selection effects and astrophysical knowledge. We also search for distortions to the gravitational waveform caused by 1) frequency-independent phase shifts in strongly lensed images, and 2) frequency-dependent modulation of the amplitude and phase due to point masses. None of these searches yields significant evidence for lensing. Finally, we use the non-detection of gravitational-wave lensing to constrain the lensing rate based on the latest merger-rate estimates and the fraction of dark matter composed of compact objects

    Search for eccentric black hole coalescences during the third observing run of LIGO and Virgo

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    Despite the growing number of confident binary black hole coalescences observed through gravitational waves so far, the astrophysical origin of these binaries remains uncertain. Orbital eccentricity is one of the clearest tracers of binary formation channels. Identifying binary eccentricity, however, remains challenging due to the limited availability of gravitational waveforms that include effects of eccentricity. Here, we present observational results for a waveform-independent search sensitive to eccentric black hole coalescences, covering the third observing run (O3) of the LIGO and Virgo detectors. We identified no new high-significance candidates beyond those that were already identified with searches focusing on quasi-circular binaries. We determine the sensitivity of our search to high-mass (total mass M&gt;70 M⊙) binaries covering eccentricities up to 0.3 at 15 Hz orbital frequency, and use this to compare model predictions to search results. Assuming all detections are indeed quasi-circular, for our fiducial population model, we place an upper limit for the merger rate density of high-mass binaries with eccentricities 0&lt;e≤0.3 at 0.33 Gpc−3 yr−1 at 90\% confidence level

    Ultralight vector dark matter search using data from the KAGRA O3GK run

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    Among the various candidates for dark matter (DM), ultralight vector DM can be probed by laser interferometric gravitational wave detectors through the measurement of oscillating length changes in the arm cavities. In this context, KAGRA has a unique feature due to differing compositions of its mirrors, enhancing the signal of vector DM in the length change in the auxiliary channels. Here we present the result of a search for U(1)B−L gauge boson DM using the KAGRA data from auxiliary length channels during the first joint observation run together with GEO600. By applying our search pipeline, which takes into account the stochastic nature of ultralight DM, upper bounds on the coupling strength between the U(1)B−L gauge boson and ordinary matter are obtained for a range of DM masses. While our constraints are less stringent than those derived from previous experiments, this study demonstrates the applicability of our method to the lower-mass vector DM search, which is made difficult in this measurement by the short observation time compared to the auto-correlation time scale of DM
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