117 research outputs found
The potential for Port 4.0 in a small Norwegian seaport - A case study of the Port of Kristiansand's container terminal
The Port and Maritime industry has since the 2010s undergone a significant digital transformation and is facing new challenges such as increased pressure regarding productivity, sustainability, as well as security and safety risks. This has, among other things, led to the development of smart ports. However, the adoption of automation has taken place in a slower pace than comparable sectors. Moreover, the literature related to smart port development in Norway is perceived as limited. Therefore, this study has attempted to elaborate a field of research to aid the port of Kristiansand and similar ports in Norway to develop into smart ports. The methodology of this thesis provides a qualitative approach for investigating the smart port potential in a small container terminal. Our study shows that the Port of Kristiansand is in an early stage towards a smart port status. Additionally, our findings indicate that there are substantial opportunities and potential for further development
The potential for Port 4.0 in a small Norwegian seaport - A case study of the Port of Kristiansand’s container terminal
The Port and Maritime industry has since the 2010s undergone a significant digital transformation and is facing new challenges such as increased pressure regarding productivity, sustainability, as well as security and safety risks. This has, among other things, led to the development of smart ports. However, the adoption of automation has taken place in a slower pace than comparable sectors. Moreover, the literature related to smart port development in Norway is perceived as limited. Therefore, this study has attempted to elaborate a field of research to aid the port of Kristiansand and similar ports in Norway to develop into smart ports. The methodology of this thesis provides a qualitative approach for investigating the smart port potential in a small container terminal. Our study shows that the Port of Kristiansand is in an early stage towards a smart port status. Additionally, our findings indicate that there are substantial opportunities and potential for further development
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Quantum Chemical Approach to Estimating the Thermodynamics of Metabolic Reactions
Thermodynamics plays an increasingly important role in modeling and engineering metabolism. We present the first nonempirical computational method for estimating standard Gibbs reaction energies of metabolic reactions based on quantum chemistry, which can help fill in the gaps in the existing thermodynamic data. When applied to a test set of reactions from core metabolism, the quantum chemical approach is comparable in accuracy to group contribution methods for isomerization and group transfer reactions and for reactions not including multiply charged anions. The errors in standard Gibbs reaction energy estimates are correlated with the charges of the participating molecules. The quantum chemical approach is amenable to systematic improvements and holds potential for providing thermodynamic data for all of metabolism.Chemistry and Chemical Biolog
The anti-obesogenic effect of lean fish species is influenced by the fatty acid composition in fish fillets
publishedVersio
Privacy-Preserving Observation in Public Spaces
One method of privacy-preserving accounting or billing in cyber-physical systems, such as electronic toll collection or public transportation ticketing, is to have the user present an encrypted record of transactions and perform the accounting or billing computation securely on them. Honesty of the user is ensured by spot checking the record for some selected surveyed transactions. But how much privacy does that give the user, i.e. how many transactions need to be surveyed? It turns out that due to collusion in mass surveillance all transactions need to be observed, i.e. this method of spot checking provides no privacy at all. In this paper we present a cryptographic solution to the spot checking problem in cyber-physical systems. Users carry an authentication device that authenticates only based on fair random coins. The probability can be set high enough to allow for spot checking, but in all other cases privacy is perfectly preserved. We analyze our protocol for computational efficiency and show that it can be efficiently implemented even on plat- forms with limited computing resources, such as smart cards and smart phones
Dietary fat drives whole-body insulin resistance and promotes intestinal inflammation independent of body weight gain
Heritable Stochastic Switching Revealed by Single-Cell Genealogy
The partitioning and subsequent inheritance of cellular factors like proteins and RNAs is a ubiquitous feature of cell division. However, direct quantitative measures of how such nongenetic inheritance affects subsequent changes in gene expression have been lacking. We tracked families of the yeast Saccharomyces cerevisiae as they switch between two semi-stable epigenetic states. We found that long after two cells have divided, they continued to switch in a synchronized manner, whereas individual cells have exponentially distributed switching times. By comparing these results to a Poisson process, we show that the time evolution of an epigenetic state depends initially on inherited factors, with stochastic processes requiring several generations to decorrelate closely related cells. Finally, a simple stochastic model demonstrates that a single fluctuating regulatory protein that is synthesized in large bursts can explain the bulk of our results
Lysates of Methylococcus capsulatus Bath induce a lean-like microbiota, intestinal FoxP3+RORγt+IL-17+ Tregs and improve metabolism
Interactions between host and gut microbial communities are modulated by diets and play pivotal roles in immunological homeostasis and health. We show that exchanging the protein source in a high fat, high sugar, westernized diet from casein to whole-cell lysates of the non-commensal bacterium Methylococcus capsulatus Bath is sufficient to reverse western diet-induced changes in the gut microbiota to a state resembling that of lean, low fat diet-fed mice, both under mild thermal stress (T22 °C) and at thermoneutrality (T30 °C). Concomitant with microbiota changes, mice fed the Methylococcus-based western diet exhibit improved glucose regulation, reduced body and liver fat, and diminished hepatic immune infiltration. Intake of the Methylococcu-based diet markedly boosts Parabacteroides abundances in a manner depending on adaptive immunity, and upregulates triple positive (Foxp3+RORγt+IL-17+) regulatory T cells in the small and large intestine. Collectively, these data point to the potential for leveraging the use of McB lysates to improve immunometabolic homeostasis.publishedVersio
Global sea-level budget and ocean-mass budget, with a focus on advanced data products and uncertainty characterisation
Studies of the global sea-level budget (SLB) and the global ocean-mass budget (OMB) are essential to assess the reliability of our knowledge of sea-level change and its contributors. Here we present datasets for times series of the SLB and OMB elements developed in the framework of ESA's Climate Change Initiative. We use these datasets to assess the SLB and the OMB simultaneously, utilising a consistent framework of uncertainty characterisation. The time series, given at monthly sampling and available at https://doi.org/10.5285/17c2ce31784048de93996275ee976fff (Horwath et al., 2021), include global mean sea-level (GMSL) anomalies from satellite altimetry, the global mean steric component from Argo drifter data with incorporation of sea surface temperature data, the ocean-mass component from Gravity Recovery and Climate Experiment (GRACE) satellite gravimetry, the contribution from global glacier mass changes assessed by a global glacier model, the contribution from Greenland Ice Sheet and Antarctic Ice Sheet mass changes assessed by satellite radar altimetry and by GRACE, and the contribution from land water storage anomalies assessed by the global hydrological model WaterGAP (Water Global Assessment and Prognosis). Over the period January 1993–December 2016 (P1, covered by the satellite altimetry records), the mean rate (linear trend) of GMSL is 3.05 ± 0.24 mm yr−1. The steric component is 1.15 ± 0.12 mm yr−1 (38 % of the GMSL trend), and the mass component is 1.75 ± 0.12 mm yr−1 (57 %). The mass component includes 0.64  ± 0.03 mm yr−1 (21 % of the GMSL trend) from glaciers outside Greenland and Antarctica, 0.60 ± 0.04 mm yr−1 (20 %) from Greenland, 0.19 ± 0.04 mm yr−1 (6 %) from Antarctica, and 0.32 ± 0.10 mm yr−1 (10 %) from changes of land water storage. In the period January 2003–August 2016 (P2, covered by GRACE and the Argo drifter system), GMSL rise is higher than in P1 at 3.64 ± 0.26 mm yr−1. This is due to an increase of the mass contributions, now about 2.40 ± 0.13 mm yr−1 (66 % of the GMSL trend), with the largest increase contributed from Greenland, while the steric contribution remained similar at 1.19 ± 0.17 mm yr−1 (now 33 %). The SLB of linear trends is closed for P1 and P2; that is, the GMSL trend agrees with the sum of the steric and mass components within their combined uncertainties. The OMB, which can be evaluated only for P2, shows that our preferred GRACE-based estimate of the ocean-mass trend agrees with the sum of mass contributions within 1.5 times or 0.8 times the combined 1σ uncertainties, depending on the way of assessing the mass contributions. Combined uncertainties (1σ) of the elements involved in the budgets are between 0.29 and 0.42 mm yr−1, on the order of 10 % of GMSL rise. Interannual variations that overlie the long-term trends are coherently represented by the elements of the SLB and the OMB. Even at the level of monthly anomalies the budgets are closed within uncertainties, while also indicating possible origins of remaining misclosures
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