Reconstruction of Holocene environmental changes in North-Western Pacific in relation to paleorecord from Shikotan Island

Results of a paleolimnological investigation of a well-dated lake sediment section from Shikotan Island (Southern Kurils) showed that from ca 8.0 to 5.8 cal ka BP a warm and humid period corresponding to middle Holocene optimum took place. Cooling thereafter corresponds to Neoglacial. A reconstructed from ca 0.9 to ca 0.58 cal ka BP warm period can correspond to a Medieval Warm Period. Cooling after 0.58 cal ka BP can be correlated with the LIA. Marine regression stages were identified at ca 6.2–5.9, 5.5– 5.1 and 1.07–0.36 cal ka BP. The general chronology of major climatic events of Holocene in the island is in accordance with the climate records from the North Pacific region. Revealed spatial differences in timing and magnitude of the Late Holocene climatic episodes (LIA, MWP) in the region needs further investigations

The Eurasian Modern Pollen Database (EMPD), version 2

The Eurasian (née European) Modern Pollen Database (EMPD) was established in 2013 to provide a public database of high-quality modern pollen surface samples to help support studies of past climate, land cover, and land use using fossil pollen. The EMPD is part of, and complementary to, the European Pollen Database (EPD) which contains data on fossil pollen found in Late Quaternary sedimentary archives throughout the Eurasian region. The EPD is in turn part of the rapidly growing Neotoma database, which is now the primary home for global palaeoecological data. This paper describes version 2 of the EMPD in which the number of samples held in the database has been increased by 60 % from 4826 to 8134. Much of the improvement in data coverage has come from northern Asia, and the database has consequently been renamed the Eurasian Modern Pollen Database to reflect this geographical enlargement. The EMPD can be viewed online using a dedicated map-based viewer at https://empd2.github.io and downloaded in a variety of file formats at https://doi.pangaea.de/10.1594/PANGAEA.909130 (Chevalier et al., 2019)Swiss National Science Foundation | Ref. 200021_16959

The Eurasian Modern Pollen Database (EMPD), version 2

The Eurasian (nee European) Modern Pollen Database (EMPD) was established in 2013 to provide a public database of high-quality modern pollen surface samples to help support studies of past climate, land cover, and land use using fossil pollen. The EMPD is part of, and complementary to, the European Pollen Database (EPD) which contains data on fossil pollen found in Late Quaternary sedimentary archives throughout the Eurasian region. The EPD is in turn part of the rapidly growing Neotoma database, which is now the primary home for global palaeoecological data. This paper describes version 2 of the EMPD in which the number of samples held in the database has been increased by 60% from 4826 to 8134. Much of the improvement in data coverage has come from northern Asia, and the database has consequently been renamed the Eurasian Modern Pollen Database to reflect this geographical enlargement. The EMPD can be viewed online using a dedicated map-based viewer at https://empd2.github.io and downloaded in a variety of file formats at https://doi.pangaea.de/10.1594/PANGAEA.909130 (Chevalier et al., 2019).Peer reviewe

Selection of DNA Aptamers for Breast Cancer

Текст статьи не публикуется в открытом доступе в соответствии с политикой журнала.A method of selection of DNA aptamers to breast tumor tissue based on the use of potoperative material has been developed. Breast cancer tissue were used as the positive target; the negative targets included benign tumor tissue, adjacent healthy tissue, breast tissues from mastopathy patients, and also tissue of other types of malignant tumors/ Tese DNA aptamers can be used for identification of protein markars, breast cancer diagnostics, and targeted delivery of anticancer drugs

Selection of DNA Aptamers for Breast Cancer

Текст статьи не публикуется в открытом доступе в соответствии с политикой журнала.A method of selection of DNA aptamers to breast tumor tissue based on the use of potoperative material has been developed. Breast cancer tissue were used as the positive target; the negative targets included benign tumor tissue, adjacent healthy tissue, breast tissues from mastopathy patients, and also tissue of other types of malignant tumors/ Tese DNA aptamers can be used for identification of protein markars, breast cancer diagnostics, and targeted delivery of anticancer drugs