El éxito académico en el primer año de la carrera de Ingeniería Industrial y su vínculo con factores académicos previos

A significant number of students get access to the Faculty of Industrial Engineering of the Technological University of Havana. It produces a volume of data that can be analyzed in order to manage the educational process intentionally. In this study, descriptive statistics techniques are used to extract useful and relevant information from the educational data recorded during the process of professional training. The objective of this work is to analyze information obtained from the first-year students enrolled in the academic courses between 2012 and 2017 to improve their academic performance. The analysis of a set of data to study possible associations shows a reduction of academic efficiency. Technical and software statistical packages were used to process available data. The results obtained point out the significant impact of some admission processes parameters over first year student academic success.  En la facultad de Ingeniería Industrial de la Universidad Tecnológica de La Habana ingresa una cantidad significativa de estudiantes de los que se dispone un volumen de datos, que pueden ser analizados para contribuir a gestionar el proceso de formación de manera intencionada. En este estudio se utilizan técnicas de estadística descriptiva que permiten extraer información útil y relevante de los datos educacionales que son registrados como entradas o resultados del proceso de formación de profesionales. El objetivo de este trabajo es analizar información obtenida de los estudiantes de primer año académico de la carrera matriculados en los cursos académicos entre el 2012 y el 2017 para la mejora de su rendimiento académico. Se muestra el análisis de un conjunto de datos para estudiar posibles correlaciones entre factores influyentes lo que permite apreciar una disminución en la promoción y en la eficiencia académica. Se utilizaron para el procesamiento de los datos educacionales, técnicas y paquetes computacionales estadísticos. Los resultados obtenidos indican la relevancia que tienen los niveles de ingreso de los estudiantes en primer año para lograr el éxito académico

ARQUITECTURA COMPUTACIONAL PARA PREDECIR EL RENDIMIENTO ACADÉMICO DE ALUMNOS DE LA UNIVERSIDAD AGOSTINHO NETO

El estudio de los factores que intervienen en el rendimiento académico de los alumnos ha sido y sigue siendo un tema objeto de investigación pedagógica por cuanto aporta información de mucho valor en el proceso de personalización de la enseñanza y en la mejora del sistema educativo en su conjunto. A pesar de que esa información puede dar un indicio sobre las dificultades que presentarán individualmente los alumnos durante sus estudios inmediatos y futuros, es conveniente disponer de algún procedimiento que permita predecir con alguna certeza cuál será su rendimiento al finalizar un período. Este conocimiento facilitaría la creación de intervenciones oportunas que favorezcan un mejor aprendizaje de cada alumno en función de sus características personales. Para analizar la relación entre un grupo de factores que caracterizan a los alumnos que ingresan en la carrera de Ciencia de la Computación de la UAN y su rendimiento académico al finalizar el primer año se propone la utilización de un modelo de red neuronal del tipo Perceptron Multicapa (MLP), debido a su buen desempeño en la predicción del comportamiento de sistemas complejos. En este trabajo se describe una arquitectura computacional, que incluye una red neuronal MLP, con el fin de realizar una predicción del desempeño académico de los estudiantes al finalizar el primer año de la carrera

DETERMINACIÓN DE COMPETENCIAS EN ENTIDADES DE SERVICIO PÚBLICO. CASO DE ESTUDIO ESTACIÓN POLICIAL

The use of the competencies approachwithin public service organization is a requirement of a strategic management of human capital and the possibility to improve the efficiency of the work. Through a case of study, the goal of this article is to show how to establishthe organizational, processes and working position competencies within a police station. The obtained results indicate the relevance of the competenciesapproach in the organizational model of the police organizations and the current state competencies system in the reference station.El uso del enfoque de competencias en entidades de servicio público es requisito de una gestión estratégica del capital humano y la posibilidad de un trabajo más eficiente.El objetivo de este artículo es mostrar, a través de un caso de estudio, un procedimiento para determinar las competencias organizacionales, de procesos y de puestos en una estación policial. Los resultados obtenidos indican la pertinencia del enfoque de competencia en el modelo organizacional de las entidades policiales y el estado actual del sistema de competencias en la estación de referencia

Identificación de factores influyentes en el éxito académico de estudiantes de primer año en la universidad Agostinho Neto

En el rendimiento académico dentro de la universidad influyen muchos factores, los que se manifiestan principalmente en el primer año de la carrera. Sin embargo, los factores influyentes y los resultados que se han presentado en estudios previos no son iguales en diferentes universidades. Este trabajo presenta una aproximación para identificar un grupo de factores o variables que puede incidir en que los estudiantes que ingresan en la carrera de Ciencias de la Computación en la universidad Agostinho Neto, de Angola, puedan tener éxito en dos materias de contenidos esenciales dentro de la carrera: Lógica de Programación y Programación Imperativa. Se analizan desde el punto de vista psicopedagógico y social, las razones que explican la selección de esas variables y se contrasta con un análisis correlacional para estimar la posible asociación entre cada variable independiente y la variable criterio. La información empleada corresponde a tres cursos (unos 800 alumnos). Los resultados de aplicar el estadístico Chi-cuadrado a tablas de contingencia sugieren un grupo de aspectos que más influyen en tener éxito en las asignaturas Lógica de Programación y Programación Imperativa.The low academic performance at the university is influenced by many factors manifested mainly in the early years of study. However, the influential factors and the results presented in previous studies are different depending on the kind of universities. This work presents an approach to identify a group of factors or variables affecting the low academic performance of students in Computer Science in the university Agostinho Neto, of Angola, during first year of studies, specifically in two essential subjects of the course: Logic of Programming and Imperative Programming. From the psychological, pedagogical and social point of view the reasons to select those variables is analyzed and is compared by mean of a correlacional analysis for estimating the possible association between each independent variable and the variable criteria. Information employed belongs to three courses (about 800 students). The results of applying the statistical Chi-square to contingency tables suggest a group of aspects that more mainly influence in achieve successful in the subjects Logic of Programming and Imperative Programming.Facultad de Informátic

THE PERSONS MANAGEMENT IN ENTERPRISES OF BIOTECHNICAL PHARMACIST SECTOR

El objetivo de este artículo es establecer algunos requerimientos que demanda la gestión del capital humano en empresas de alta tecnología del sector biotecnológico farmacéutico cubano. El estudio se realiza a partir del empleo del método histórico lógico, la modelación, así como el análisis documental, la observación directa, y el método de expertos. Para cumplir con el objetivo general fue necesario utilizar el estudio de caso como método de investigación científica, que permite investigar la gestión del capital humano de las Empresas de Alta Tecnología del sector biotecnológico farmacéutico cubano, en su contexto real y con todas sus complejidades asociadas. Los resultados conducen al establecimiento de un modelo conceptual particular que tiene en cuenta las singularidades de un sector que se distingue por el uso intensivo del conocimiento y empresas de ciclo completo. Además, se muestra un procedimiento de aplicación general, con procedimientos específicos de trabajo, para cuyo diseño se tomaron en consideración las mejores prácticas desarrolladas en diferentes centros en materia de capital humano.The objective of this article is to establish some requirements demanded by the management of human capital in high technology companies of the Cuban pharmaceutical biotechnology sector. The study is based on the use of the logical historical method, the modeling, as well as the documentary analysis, direct observation, and the expert method. In order to comply with the general objective, it was necessary to use the case study as a scientific research method, which allows investigating the human capital management of the High Technology Companies of the Cuban pharmaceutical biotechnology sector, in its real context and with all its complexities associated. The results lead to the establishment of a particular conceptual model that takes into account the singularities of a sector that is distinguished by the intensive use of knowledge and full-cycle companies. In addition, a general application procedure is shown, with specific work procedures, for which the best practices developed in different centers regarding human capital were taken into consideration.&nbsp

DETERMINACIÓN DEL SISTEMA DE COMPETENCIAS DEL PROCESO DE POSGRADO EN CENTROS DE INVESTIGACIÓN. CASO DE ESTUDIO: INSTITUTO DE CIENCIA ANIMAL

Much has been said about the importance of human capital in organizations and especially in the research centers, which exhibit growing needs to guarantee people's skill training. The objective of this study was to determine the competence system of the Postgraduate Process in the Institute of Animal Science, using techniques and tools such as: Critical Incident Interview and Critical Examination. As a result, 6 competences representative of the Postgraduate process were obtained with values ​​of agreement higher than 65%, expressing agreement among the experts in the definition of: Professional rigor, Ethic, Teamwork, and Search for excellence, Interest in keeping up to date and Innovation and creativity. The key positions for the process and the associated competencies for the superior performance of said positions were also defined. The competences identified can serve as a reference to other centers.Mucho se ha hablado de la importancia que tiene el capital humano en las organizaciones y en especial en los centros de investigación, los que exhiben necesidades crecientes de garantizar la formación por competencias de las personas. El trabajo tiene como objetivo determinar el sistema de competencias del proceso de Posgrado en el Instituto de Ciencia Animal, a partir de técnicas y herramientas tales como: Entrevista de Incidente Crítico y Examen Crítico. Como resultado se obtuvieron 6 competencias representativas del proceso de Posgrado con valores de concordancia superiores al 65%, expresando acuerdo entre los expertos en la definición de: Rigor profesional, Ética, Trabajo en equipo, Búsqueda de la excelencia, Interés por mantenerse actualizado e Innovación y creatividad. Se definieron además los cargos claves para el proceso y las competencias asociadas para el desempeño superior de dichos cargos. Las competencias identificadas pueden servir de referencia a otros centros

The Effect of Physical Activity and High Body Mass Index on Health-Related Quality of Life in Individuals with Metabolic Syndrome

[EN] The main objective of this study was to examine the relationship between the level of physical activity (PA) and the degree of obesity with health-related quality of life (HRQoL) in individuals with metabolic syndrome (MetS) who participated in the Predimed-Plus study. A total of 6875 subjects between 55 and 75 years of age with MetS were selected and randomized in 23 Spanish centers. Subjects were classified according to categories of body mass index (BMI). PA was measured with the validated Registre Gironi del Cor (REGICOR) questionnaire and subjects were classified according to their PA level (light, moderate, vigorous) and the HRQoL was measured with the validated short-form 36 (SF-36) questionnaire. By using the ANOVA model, we found a positive and statistically significant association between the level of PA and the HRQoL (aggregated physical and mental dimensions p < 0.001), but a negative association with higher BMI in aggregated physical dimensions p < 0.001. Furthermore, women obtained lower scores compared with men, more five points in all fields of SF-36. Therefore, it is essential to promote PA and body weight control from primary care consultations to improve HRQoL, paying special attention to the differences that sex incurs.SIThe Predimed-Plus trial was supported by the Spanish government’s official funding agency for biomedical research, ISCIII, through the Fondo de Investigación para la Salud (FIS), which is co-funded by the European Regional Development Fund (three coordinated FIS projects led by Jordi Salas-Salvadó and Josep Vidal, including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/0147, PI14/00636, PI14/00972, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926, PI19/00957, PI19/00386, PI19/00309, PI19/01032, PI19/00576, PI19/00017, PI19/01226, PI19/00781, PI19/01560, PI19/01,332), the Special Action Project entitled: Implementación y evaluación de una intervención intensiva sobre la actividad física Cohorte PREDIMED-PLUS grant to Jordi Salas-Salvadó, the European Research Council (Advanced Research Grant 2013–2018; 340918) grant to Miguel Ángel Martínez-Gonzalez, the Recercaixa grant to Jordi Salas-Salvadó (2013ACUP00194), grants from the Consejería de Salud de la Junta de Andalucía (PI0458/2013; PS0358/2016; PI0137/2018), the PROMETEO/2017/017 grant from the Generalitat Valenciana, the SEMERGEN grant and FEDER funds (CB06/03 and CB12/03), Olga Castaner is funded by the JR17/00,022 grant, ISCIII. Christopher Papandreou is supported by a postdoctoral fellowship granted by the Autonomous Government of Catalonia (PERIS 2016–2020 Incorporació de Científics i Tecnòlegs, SLT002/0016/00,428). María Rosa Bernal-Lopez was supported by “Miguel Servet Type I” program (CP15/00028) from the ISCIII-Madrid (Spain), cofinanced by the Fondo Europeo de Desarrollo Regional-FEDER, Ignacio M.Giménez-Alba is supported by a FPU predoctoral contract (reference FPU18/01703) from the Ministerio de Ciencia, Innovación y Universidades, Spain

Dietary diversity and depression: cross-sectional and longitudinal analyses in Spanish adult population with metabolic syndrome. Findings from PREDIMED-Plus trial

Objective: To examine the cross-sectional and longitudinal (2-year follow-up) associations between dietary diversity (DD) and depressive symptoms. Design: An energy-adjusted dietary diversity score (DDS) was assessed using a validated FFQ and was categorised into quartiles (Q). The variety in each food group was classified into four categories of diversity (C). Depressive symptoms were assessed with Beck Depression Inventory-II (Beck II) questionnaire and depression cases defined as physician-diagnosed or Beck II >= 18. Linear and logistic regression models were used. Setting: Spanish older adults with metabolic syndrome (MetS). Participants: A total of 6625 adults aged 55–75 years from the PREDIMED-Plus study with overweight or obesity and MetS. Results: Total DDS was inversely and statistically significantly associated with depression in the cross-sectional analysis conducted; OR Q4 v. Q1 = 0·76 (95 % CI (0·64, 0·90)). This was driven by high diversity compared to low diversity (C3 v. C1) of vegetables (OR = 0·75, 95 % CI (0·57, 0·93)), cereals (OR = 0·72 (95 % CI (0·56, 0·94)) and proteins (OR = 0·27, 95 % CI (0·11, 0·62)). In the longitudinal analysis, there was no significant association between the baseline DDS and changes in depressive symptoms after 2 years of follow-up, except for DD in vegetables C4 v. C1 = (β = 0·70, 95 % CI (0·05, 1·35)). Conclusions: According to our results, DD is inversely associated with depressive symptoms, but eating more diverse does not seem to reduce the risk of future depression. Additional longitudinal studies (with longer follow-up) are needed to confirm these findings.T The PREDIMED-Plus trial was supported by the European Research Council (Advanced Research Grant 2013-2018; 340918) grant to Miguel Angel Martinez-Gonzalez, and by the official funding agency for biomedical research of the Spanish Government, ISCIII through the Fondo de Investigacion para la Salud (FIS), which is cofunded by the European Regional Development Fund (four coordinated FIS projects led by Jordi Salas-Salvado and Josep Vidal), including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926, The Especial Action Project entitled: 'Implementacion y Evaluacion de una intervencion intensiva sobre la actividad fisica Cohorte PREDIMED-Plus' grant to Jordi Salas-Salvado, the Recercaixa grant to Jordi Salas-Salvado (2013ACUP00194), grants from the Consejeria de Salud de la Junta de Andalucia (PI0458/2013; PS0358/2016; PI0137/2018), the PROMETEO/2017/017 grant from the Generalitat Valenciana, the SEMERGEN grant, and CIBEROBN and FEDER funds (CB06/03), ISCIII. International Nut&Dried Fruit Council-FESNAD N degrees 201302: Miguel Angel Martinez-Gonzalez (PI). None of the funding sources took part in the design, collection, analysis or interpretation of the data, or in the decision to submit the manuscript for publication. The corresponding author had full access to all the data in the study and had final responsibility to submit for publication

Contribution of cardio-vascular risk factors to depressive status in the PREDIMED-PLUS Trial. A cross-sectional and a 2-year longitudinal study

Background Cardio-vascular disease and depression are thought to be closely related, due to shared risk factors. The aim of the study was to determine the association between cardio-vascular risk (CVR) factors and depressive status in a population (55-75 years) with metabolic syndrome (MetS) from the PREDIMED-Plus trial. Methods and findings Participants were classified into three groups of CVR according to the Framingham-based REGICOR function: (1) low (LR), (2) medium (MR) or (3) high/very high (HR). The Beck Depression Inventory-II (BDI-II) was used to assess depressive symptoms at baseline and after 2 years. The association between CVR and depressive status at baseline (n = 6545), and their changes after 2 years (n = 4566) were evaluated through multivariable regression models (logistic and linear models). HR women showed higher odds of depressive status than LR [OR (95% CI) = 1.78 (1.26, 2.50)]. MR and HR participants with total cholesterol <160 mg/mL showed higher odds of depression than LR [OR (95% CI) = 1.77 (1.13, 2.77) and 2.83 (1.25, 6.42) respectively)] but those with total cholesterol ¿280 mg/mL showed lower odds of depression than LR [OR (95% CI) = 0.26 (0.07, 0.98) and 0.23 (0.05, 0.95), respectively]. All participants decreased their BDI-II score after 2 years, being the decrease smaller in MR and HR diabetic compared to LR [adjusted mean±SE = -0.52±0.20, -0.41 ±0.27 and -1.25±0.31 respectively). MR and HR participants with total cholesterol between 240-279 mg/mL showed greater decreases in the BDI-II score compared to LR (adjusted mean±SE = -0.83±0.37, -0.77±0.64 and 0.97±0.52 respectively). Conclusions Improving cardiovascular health could prevent the onset of depression in the elderly. Diabetes and total cholesterol in individuals at high CVR, may play a specific role in the precise response.The PREDIMED-Plus trial was supported by the European Research Council through a grant to MAM (Advanced Research Grant 2013-2018; 340918). The project was also supported by the official funding agency for biomedical research of the Spanish Government (ISCIII) through the Fondo de Investigación para la Salud (FIS), which is co-funded by the European Regional Development Fund (four coordinated FIS projects), who awarded grants to JS and JV (PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732 and PI17/00926). The International Nut&Dried Fruit Council-FESNAD also provided funding through a grant to MAM (201302), and Recercaixa also awarded a grant to JS (2013ACUP00194). The Department of Health, Generalitat de Cataluña by the calls 'Acció instrumental de programes de recerca orientats en lámbit de la recercaila innovació en salut' and 'Pla estrategic de recerca i innovació en salut (PERIS),' also awarded a grant to FF (SLT006/17/00246). This research was also partially funded by: Consejería de Salud de la Junta de Andalucía (PI0458/2013, PS0358/2016, PI0137/2018); Generalitat Valenciana (PROMETEO/2017/017); SEMERGEN, CIBEROBN, FEDER and ISCIII (CB06/03); EU-H2020 Grants (Eat2beNICE/h2020-sfs-2016-2, ref.728018; PRIME/h2020-SC1-BHC-2018-2020, ref: 847879)

Prospective associations between a priori dietary patterns adherence and kidney function in an elderly Mediterranean population at high cardiovascular risk

Purpose To assess the association between three different a priori dietary patterns adherence (17-item energy reduced-Mediterranean Diet (MedDiet), Trichopoulou-MedDiet and Dietary Approach to Stop Hypertension (DASH)), as well as the Protein Diet Score and kidney function decline after one year of follow-up in elderly individuals with overweight/obesity and metabolic syndrome (MetS). Methods We prospectively analyzed 5675 participants (55-75 years) from the PREDIMED-Plus study. At baseline and at one year, we evaluated the creatinine-based estimated glomerular filtration rate (eGFR) and food-frequency questionnaires-derived dietary scores. Associations between four categories (decrease/maintenance and tertiles of increase) of each dietary pattern and changes in eGFR (ml/min/1.73m(2)) or >= 10% eGFR decline were assessed by fitting multivariable linear or logistic regression models, as appropriate. Results Participants in the highest tertile of increase in 17-item erMedDiet Score showed higher upward changes in eGFR (beta: 1.87 ml/min/1.73m(2); 95% CI: 1.00-2.73) and had lower odds of >= 10% eGFR decline (OR: 0.62; 95% CI: 0.47-0.82) compared to individuals in the decrease/maintenance category, while Trichopoulou-MedDiet and DASH Scores were not associated with any renal outcomes. Those in the highest tertile of increase in Protein Diet Score had greater downward changes in eGFR (beta: - 0.87 ml/min/1.73m(2); 95% CI: - 1.73 to - 0.01) and 32% higher odds of eGFR decline (OR: 1.32; 95% CI: 1.00-1.75). Conclusions Among elderly individuals with overweight/obesity and MetS, only higher upward change in the 17-item erMedDiet score adherence was associated with better kidney function after one year. However, increasing Protein Diet Score appeared to have an adverse impact on kidney health. Trial Registration Number: ISRCTN89898870 (Data of registration: 2014).Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. This work was supported by the official Spanish Institutions for funding scientific biomedical research, CIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN) and Instituto de Salud Carlos III (ISCIII), through the Fondo de Investigacion para la Salud (FIS), which is co-funded by the European Regional Development Fund (six coordinated FIS projects leaded by JS-S and JVi, including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926, PI19/00957, PI19/00386, PI19/00309, PI19/01032, PI19/00576, PI19/00017, PI19/01226, PI19/00781, PI19/01560, PI19/01332, PI20/01802, PI20/00138, PI20/01532, PI20/00456, PI20/00339, PI20/00557, PI20/00886, PI20/01158); the Especial Action Project entitled: Implementacion y evaluacion de una intervencion intensiva sobre la actividad fisica Cohorte PREDIMED-Plus grant to JS-S; the European Research Council (Advanced Research Grant 2014-2019; agreement #340918) granted to MAMG.; the Recercaixa (number 2013ACUP00194) grant to JS-S; grants from the Consejeria de Salud de la Junta de Andalucia (PI0458/2013, PS0358/2016, PI0137/2018); the PROMETEO/2017/017 and the PROMETEO 21/2021 grant from the Generalitat Valenciana; the SEMERGEN grant; the Boosting young talent call grant program for the development of IISPV research projects 2019-2021 (Ref.: 2019/IISPV/03 grant to AD-L); the Societat Catalana d'Endocrinologia i Nutricio (SCEN) Clinical-Research Grant 2019 (IPs: JS-S and AD-L). Collaborative Nutrition and/or Obesity Project for Young Researchers 2019 supported by CIBEROBN entitled: Lifestyle Interventions and Chronic Kidney Disease: Inflammation, Oxidative Stress and Metabolomic Profile (LIKIDI study) grant to AD-L. Jordi Salas-Salvado, gratefully acknowledges the financial support by ICREA under the ICREA Academia programme. M.R.-G., is supported by the Ministry of Education of Spain (FPU17/06488). None of the funding sources took part in the design, collection, analysis, interpretation of the data, or writing the report, or in the decision to submit the manuscript for publication