DETERMINACIÓN DE LAS FUNCIONES Y SERVICIOS PRESTADOS POR LOS COMPONENTES DE LA SAN DEL CECAD DE LA UNIVERSIDAD DISTRITAL FRANCISCO JOSÉ DE CALDAS

En este artículo se asignan las funciones y servicios que deben prestar los componentes de la Red de Almacenamiento  del Centro de Cómputo de Alto desempeño de la Universidad  Distrital Francisco José de Caldas. Para alcanzar este objetivo se realizaron varias pruebas entre los diferentes elementos  que conforman la SAN y se midieron las velocidades de  transferencia con la ayuda de herramientas especializadas

Operadores logísticos de la sociedad portuaria de santa marta: un análisis comparativo con el Puerto Santos de Brasil

En la actualidad, la globalización se ha convertido en un proceso multidimensional con una progresiva comunicación e interdependencia entre países, en donde los procesos logísticos y el transporte entre ellos el marítimo han tomado un papel fundamental para el comercio y la competitividad. Colombia cuenta con importantes puertos marítimos como el de Santa Marta, siendo este el terminal de contenedores más profundo y con mejores condiciones climáticas de América. El propósito de este artículo es identificar los operadores logísticos y las oportunidades que el puerto ofrece, bajo fundamentos de diversas fuentes bibliográficas certeras que toman como punto de comparación la eficiencia del puerto de Santos en Brasil, el cual se ha posicionado como uno de los principales terminales de América Latina, de tal forma que, al comparar sus servicios y procesos logísticos, permiten un estudio más amplio de sus estrategias que pueden ser adaptables a las prácticas y aplicaciones logísticas orientadas a un ciclo de mejora continua, que encamina al puerto de Santa Marta al incremento de su competitividad internacional, por medio de recomendaciones, que ayudaran a concluir la eficiencia y eficacia del puerto, para un desempeño óptimo.At present, globalization has become a multidimensional process with progressive communication and interdependence between countries, where the logistics processes and transport between them the maritime have taken a fundamental role for trade and competitiveness. Colombia has important seaports such as Santa Marta, this being the deepest container terminal with the best climatic conditions in America. The purpose of this article is to identify the logistics operators and the opportunities that the port offers, on the basis of various accurate bibliographic sources that take as a point of comparison the efficiency of the port of Santos in Brazil, which has positioned itself as one of the main Latin American terminals, so that, when comparing their services and logistics processes, allow a broader study of their strategies that can be adaptable to logistics practices and applications oriented to a cycle of continuous improvement, which lead to the port of Santa Marta to increase its international competitiveness, through recommendations, which helps to conclude the efficiency and effectiveness of the port, for optimal performance

Contribution of the Twin-Arginine Translocation System to the Intracellular Survival of Salmonella Typhimurium in Dictyostelium discoideum

The twin-arginine translocation (Tat) system is a specialized secretion pathway required for bacteria to export fully folded proteins through the cytoplasmic membrane. This system is crucial during Salmonella infection of animal hosts. In this study, we show that Salmonella enterica serovar Typhimurium (S. Typhimurium) requires the Tat system to survive and proliferate intracellularly in the social amoeba Dictyostelium discoideum. To achieve this, we developed a new infection assay to assess intracellular bacterial loads in amoeba by direct enumeration of colony forming units (CFU) at different times of infection. Using this assay we observed that a ΔtatABC mutant was internalized in higher numbers than the wild type, and was defective for intracellular survival in the amoeba at all times post infection evaluated. In addition, we assessed the effect of the ΔtatABC mutant in the social development of D. discoideum. In contrast to the wild-type strain, we observed that the mutant was unable to delay the social development of the amoeba at 2 days of co-incubation. This phenotype correlated with defects in intracellular proliferation presented by the ΔtatABC mutant in D. discoideum after 24 h of infection. All phenotypes described for the mutant were reverted by the presence of a plasmid carrying tatABC genes, indicating that abrogation of Tat system attenuates S. Typhimurium in this model organism. Overall, our results indicate that the Tat system is crucial for S. Typhimurium to survive and proliferate intracellularly in D. discoideum and for virulence in this host. To the best of our knowledge, this is the first report on the relevance of the Tat system in the interaction of any bacterial pathogen with the social amoeba D. discoideum

El balanced scorecard como herramienta de gestión para mejorar la productividad de la industria camaronera: Caso camaronera Biocultivos del Mar (Biomar) Cía. Ltda.

El Balanced Scorecard (BSC) resulta una herramienta muy importante que contribuye a que todas las empresas puedan llegar a la dialéctica de convertir sus estrategias en objetivos factibles de realizar, relacionándolos para facilitar el actuar del recurso humano y las inversiones se optimicen para lograr su máxima funcionalidad y productividad; actualmente en las organizaciones se ha convertido en una herramienta fundamental para gestionar de manera eficiente sus recursos. Bajo estos conceptos y con el interés de medir, controlar y mejorar las fases productivas en los centros de operación es como Biocultivos del mar Biomar Cía. Ltda., se ve en la necesidad de implementar un cuadro de mando integral CMI o Balanced Scorecard BSC que garantice un adecuado y correcto manejo de sus recursos y que refleje la rentabilidad sobre la inversión en cuanto a su producción de camarón; razón por la cual se pretende que con la aplicación del BSC y con los indicadores propuestos se logre maximizar la optimización de las inversiones y así lograr una mejor rentabilidad en la camaronera

Evaluating static postural control in subjects with controlled-diabetes mellitus II

Diabetes and neuropathy have been linked to postural instability. Aims: The purpose of this study is to determine how each system involved in balance is affected when challenged in a static standing posture. The goal was to identify postural instability by measuring balance through the amount of sway and weight bearing distribution in non-neuropathic controlled type II diabetics. Methods: Twelve participants (five males and seven females) with controlled type II diabetes mellitus and no history of peripheral neuropathy (Non-PN cDMII) formed the diabetic group, whereas eighteen participants (7 males and 11 females) without type II diabetes formed the control group. The exclusion criteria was applied via a series of screening tests (Berg Balance Scale, Five Times Sit To Stand Test, Functional Reach Test and Monofilament Test). Postural stability and weight distribution during quiet standing were measured using a Tekscan Matscan pressure mat, which measured the amount of sway and weight distribution. Static postural control was evaluated during eight sensory conditions that perturbed or stimulated the visual, proprioceptive, and vestibular systems. Results: Postural control was found to be significantly deficient when the vestibular system was stimulated, whereas the proprioceptive system was perturbed. After the data analysis, there was a significant difference in antero-posterior sway (P=0.05) with the following tasks: eyes open with head movements on an unstable surface, and eyes closed with head movements on a firm surface. Conclusions: The results revealed that the experimental group with type II diabetes had greater postural instability when compared to the control group during tasks with the vestibular system on an unstable surface. This demonstrates that, due to their deficits, individuals with non-PN cDMII are unable to maintain their balance when the vestibular and proprioceptive systems are challenged simultaneously

Absence of molecular evidence of Leptospira spp. in urine samples collected from rodents captured in Yucatán, México

Leptospira spp. is a spirochete bacteria, causal agent of leptospirosis, zoonotic disease endemic in México that represents a serious public health and veterinary problem. Rodents are recognised as the most important reservoirs of this bacteria, which is transmitted mainly through direct or indirect contact with the Leptospira spp. excreted in the urine of infected individuals. Theaim of this study was to evaluate the circulation of Leptospira spp. in urine samples of wild and synanthropic rodents from Yucatán, México. Eighty-four rodents were captured in the community of Cenotillo, Yucatán. Twenty-six urine samples were collected from the bladder and were used in the total DNA extraction. The identification of Leptospira spp. was intended through the polymerase chain reaction test in its endpoint variant. No evidence of Leptospira spp. was found in the urine samples. It is necessary to use other tissues for the identification of Leptospira spp., before concluding that the rodents used in the present study are not reservoirs of this bacteri

Molecular detection of pathogenic Leptospira in synanthropic and wild rodents captured in Yucatán, México

Introduction: Leptospirosis is a zoonotic disease caused by bacteria of the genus Leptospira, which is endemic in México and considered a public and veterinary health problem. Rodents are the most relevant reservoirs of Leptospira spp. because the bacteria establish and reproduce in its renal tissue and are excreted through the urine. Objective: To identify the presence of Leptospira spp. in renal tissue from rodents captured in Yucatán, México. Materials and methods: Synanthropic and wild rodents were captured in the rural municipality of Cenotillo, Yucatán, México. We collected one kidney from each rodent and extracted the total DNA. The identification of Leptospira spp. was done by detecting two fragments of the 16S rRNA gene using end-point polymerase chain reaction (PCR). We sequenced and analyzed positive products using alignment tools. Results: A total of 92 rodents belonging to seven different species were captured. The PCR yielded a global positivity of 5.4% (5/92). The alignment analysis of the sequenced products demonstrated a 100% of coverage and identity with Leptospira interrogans. This is the first molecular evidence of Leptospira spp. circulation in Heteromys gaumeri captured in Yucatán, México. Conclusion: Our results evidenced that rodents of Yucatán are reservoirs of Leptospira spp. and participate in the infection cycle of leptospirosis in the region

DETERMINACIÓN DE LAS FUNCIONES Y SERVICIOS PRESTADOS POR LOS COMPONENTES DE LA SAN DEL CECAD DE LA UNIVERSIDAD DISTRITAL FRANCISCO JOSÉ DE CALDAS

En este artículo se asignan las funciones y servicios que deben prestar los componentes de la Red de Almacenamiento  del Centro de Cómputo de Alto desempeño de la Universidad  Distrital Francisco José de Caldas. Para alcanzar este objetivo se realizaron varias pruebas entre los diferentes elementos  que conforman la SAN y se midieron las velocidades de  transferencia con la ayuda de herramientas especializadas

DETERMINACIÓN DE LAS FUNCIONES Y SERVICIOS PRESTADOS POR LOS COMPONENTES DE LA SAN DEL CECAD DE LA UNIVERSIDAD DISTRITAL FRANCISCO JOSÉ DE CALDAS

En este artículo se asignan las funciones y servicios que deben prestar los componentes de la Red de Almacenamiento  del Centro de Cómputo de Alto desempeño de la Universidad  Distrital Francisco José de Caldas. Para alcanzar este objetivo se realizaron varias pruebas entre los diferentes elementos  que conforman la SAN y se midieron las velocidades de  transferencia con la ayuda de herramientas especializadas.</p

Existencia de soluciones para un problema de Dirichlet sublineal

El objetivo del trabajo es ilustrar la aplicación de técnicas variacionales para la solución de un problema del análisis no lineal. Más específicamente, se demuestra que un problema de Dirichlet sublineal tiene por lo menos una solución cuando el crecimiento de la no linealidad en infinito está controlado por una recta de pendiente menor que el primer valor propio. La demostración utiliza un resultado clásico de la teoría de minimización de funcionales