The effectiveness of heat preparation and alleviation strategies for cognitive performance: A systematic review

A range of occupational and performance contexts (e.g. military personnel operations, emergency services, sport) require the critical maintenance of cognitive performance in environmentally challenging environments. Several reviews exist which evaluate the effectiveness of heat preparation strategies to facilitate physical performance. To date, no review has explored the usefulness of heat preparation strategies for cognitive performance. Therefore, this systematic review aimed to evaluate a range of interventions for the maintenance of cognitive performance, during or following active or passive heat exposure. Studies to be included were assessed by two authors reviewing title, abstract, and full-text. Forty articles were identified which met the inclusion criteria. Interventions were categorised into chronic (i.e. acclimation/acclimatisation) and acute strategies (i.e. hydration, cooling, supplementation, psychological). The results indicate that medium-term consecutive heat acclimation may mitigate some cognitive deficits under heat stress, although heat acclimation effectiveness could be influenced by age. Further, pre-cooling appears the most effective cooling method for maintaining cognitive performance under heat stress, although results were somewhat ambiguous. The hydration literature showed that the most effective hydration strategies were those which individualised electrolyte fortified fluid volumes to match for sweat loss. Limited research exploring psychological interventions indicates that motivational self-talk could be facilitative for maintaining cognitive skills following exercise in hot conditions. These findings can be used to help inform strategies for maintaining critical cognitive and decision-making skills in hot environments

Are you insulting me? Exposure to alcohol primes increases aggression following ambiguous provocation

Considerable research has shown that alcohol consumption can increase aggression and produce extremes in other social behaviors. Although most theories posit that such effects are caused by pharmacological impairment of cognitive processes, recent research indicates that exposure to alcohol-related constructs, in the absence of consumption, can produce similar effects. Here we tested the hypothesis that alcohol priming is most likely to affect aggression in the context of ambiguous provocation. Experiment 1 showed that exposure to alcohol primes increased aggressive retaliation but only when an initial provocation was ambiguous; unambiguous provocation elicited highly aggressive responses regardless of prime exposure. Experiment 2 showed that alcohol prime exposure effects are relatively short-lived and that perceptions of the provocateur’s hostility mediated effects of prime exposure on aggression. These findings suggest modification and extension of existing models of alcohol-induced aggressio

Behavioral Priming: It's All in the Mind, but Whose Mind?

The perspective that behavior is often driven by unconscious determinants has become widespread in social psychology. Bargh, Chen, and Burrows' (1996) famous study, in which participants unwittingly exposed to the stereotype of age walked slower when exiting the laboratory, was instrumental in defining this perspective. Here, we present two experiments aimed at replicating the original study. Despite the use of automated timing methods and a larger sample, our first experiment failed to show priming. Our second experiment was aimed at manipulating the beliefs of the experimenters: Half were led to think that participants would walk slower when primed congruently, and the other half was led to expect the opposite. Strikingly, we obtained a walking speed effect, but only when experimenters believed participants would indeed walk slower. This suggests that both priming and experimenters' expectations are instrumental in explaining the walking speed effect. Further, debriefing was suggestive of awareness of the primes. We conclude that unconscious behavioral priming is real, while real, involves mechanisms different from those typically assumed to cause the effect

The gatekeeper: individual differences are key in the chain from perception to behaviour

A basic assumption in mainstream social cognition is that the path from perception to behaviour is often automatic and direct, as supported for example by several experimental studies showing that priming can lead directly to a congruent behaviour without any need of conscious awareness of the process. However, we argue that the priming of a goal or an object activates individual differences in automatic evaluations at the associative level that in turn are the key predictors of action (gatekeeper model). A study (n = 90) on the American stereotype is presented to support the model. The results show that individual differences of the American stereotype as assessed with the IAT predicts a relevant action (essay evaluation) but only under condition of priming. Broader implications for predictive validity of implicit measures are also discussed

Evidence of the validity and accuracy of the Brazilian social attitude of students scale towards politics

Objetivou-se apresentar as evidências de validade e confiabilidade de uma escala brasileira para medir atitudes políticas de estudantes brasileiros de nível superior ante seus comportamentos políticos. O estudo teve uma amostra de abrangência nacional (N = 445), com estudantes brasileiros oriundos de distintos estados. Os resultados indicaram uma estrutura empírica sustentável (teste de Kaiser-Meyer-Olkin - KMO = 0,81), com indicadores psicométricos considerados adequados à mensuração das atitudes políticas. Três fatores empíricos foram identificados: grau de conhecimento sobre política (15 itens, cargas fatoriais entre 0,31 e 0,82, alfa = 0,82, eigenvalue = 5,07 e variância explicada = 18,78 %), afetos relativos à política (7 itens, cargas fatoriais entre 0,41 e 0,58, alfa = 0,72, eigenvalue = 3,17 e variância explicada = 11,73 %) e intenções de comportamento político (2 itens, cargas fatoriais entre 0,70 e 0,72, alfa = 0,80, eigenvalue = 1,8 e variância explicada = 6,8 %). Conclui-se que os resultados fortalecem a estrutura fatorial original da escala e mostram sua utilidade para a identificação de atitudes sociais ante comportamentos políticos.El objetivo de la presente investigación fue presentar las pruebas de confiabilidad y validez de una escala brasileña para medir las actitudes políticas de los estudiantes universitarios brasileños ante su comportamiento político. El estudio contó con una muestra nacional (N = 445) de estudiantes brasileños de diferentes Estados. Los resultados indicaron una estructura empírica sustentable (KMO = .81), con indicadores psicométricos que se consideran adecuados para la medición de las actitudes políticas. Específicamente, se identificaron tres factores empíricos: nivel de conocimiento sobre la política (15 ítems, cargas factoriales entre .31 y .82, alfa = .82, eigenvalue = 5.07 y varianza explicada = 18.78 %), sentimientos acerca de la política (7 ítems, factoriales de .41 y .58, alfa = .72, eigenvalue = 3.17 y varianza explicada = 11.73 °/o) e intenciones del comportamiento político (2 ítems, factoriales de .70 y .72, alfa = .80, eigenvalue = 1.8 y varianza explicada = 6.8 %). Se llegó a la conclusión de que los resultados apoyan la estructura factorial original de la escala y muestran su utilidad en la identificación de las actitudes sociales ante la conducta política.The objective of this study was to present the validity and reliability evidences of a Brazilian scale to measure the political attitudes of Brazilian higher education students regarding their political behavior. The study had a nationwide sample (N = 445), with Brazilian students from different states. The results indicated a sustainable empirical structure (KMO = 0.81), with psychometric indicators considered adequate to the measurement of political attitudes. Three empirical factors were identified: degree of political knowledge (15 items, factorial loads between 0.31 and 0.82, alpha = 0.82, eigenvalue = 5.07 and explained variance = 18.78%), feelings about politics (7 items, factorial loads between 0.41 and 0.58, alpha = 0.72, eigenvalue = 3.17 and explained variance = 11.73%) and intentions of political behavior (2 items, factorial loads between 0, 70 and 0.72, alpha = 0.80, eigenvalue = 1.8 and explained variance = 6.8%). It is concluded that the results strengthen the original factorial structure of the scale and show its utility for the identification of social attitudes regarding political behaviors

How to Do Things Without Words: Infants, utterance-activity and distributed cognition

Clark and Chalmers (1998) defend the hypothesis of an ‘Extended Mind’, maintaining that beliefs and other paradigmatic mental states can be implemented outside the central nervous system or body. Aspects of the problem of ‘language acquisition’ are considered in the light of the extended mind hypothesis. Rather than ‘language’ as typically understood, the object of study is something called ‘utterance-activity’, a term of art intended to refer to the full range of kinetic and prosodic features of the on-line behaviour of interacting humans. It is argued that utterance activity is plausibly regarded as jointly controlled by the embodied activity of interacting people, and that it contributes to the control of their behaviour. By means of specific examples it is suggested that this complex joint control facilitates easier learning of at least some features of language. This in turn suggests a striking form of the extended mind, in which infants’ cognitive powers are augmented by those of the people with whom they interact

The roles of motivation and ability in controlling the consequences of stereotype suppression

Two experiments investigated the conditions under which previously suppressed stereotypes are applied in impression formation. In Experiment 1, the extent to which a previously suppressed racial stereotype influenced subsequent impressions depended on the race of the target who was subsequently encountered. Whereas impressions of race-unspecified targets were assimilated to the stereotype following its suppression, no such effects were observed when the target belonged to the racial group whose stereotype had been initially suppressed. These results demonstrate that when perceivers are motivated to avoid stereo-typing individuals, the influence of a stereotype that has been previously activated through suppression is minimized. Experiment 2 demonstrated that these processing goals effectively reduce the impact of suppression-activated stereotypes only when perceivers have sufficient capacity to enact the goals. These results suggest that both sufficient motivation and capacity are necessary to prevent heightened stereotyping following stereotype suppression

Priming moral self-ambivalence heightens deliberative behaviour in self-ambivalent individuals

Background: Recent work on cognitive-behavioural models of obsessive-compulsive disorder has focused on the roles played by various aspects of self-perception. In particular, moral self-ambivalence has been found to be associated with obsessive-compulsive phenomena. Aims: In this study we used an experimental task to investigate whether artificially priming moral self-ambivalence would increase participants' deliberation on ethical problems, an index that might be analogous to obsessive-compulsive behaviour. Method: Non-clinical participants completed two online tasks designed to prime either moral self-ambivalence, general uncertainty, or neither. All participants then completed a task requiring them to consider solutions to moral dilemmas. We recorded the time participants took to respond to the dilemmas and the length of their responses; we then combined these variables to create a measure of deliberation. Results: Priming moral self-ambivalence led to increases in deliberation, but this was only significant among those participants who scored highly on a baseline measure of moral self-ambivalence. Priming general uncertainty had no significant effect upon deliberation. Conclusions: The results suggest that moral self-ambivalence may play a role in the maintenance of obsessive-compulsive behaviour. We propose that individuals who are morally self-ambivalent might respond to situations in which this ambivalence is made salient by exhibiting behaviour with obsessive-compulsive characteristics. These findings have implications for the incorporation of ideas about self-concept into theories of obsessive-compulsive disorder

Characterization of a single-use stirred-tank bioreactor vessel for microcarrier-based adherent cell culture processes using experimental and computational fluid dynamics studies

Renewed interest in microcarrier-based processes for the large-scale culture of adherent cells for vaccine and cell therapy applications drives the need for effective, high-throughput, single-use, process development tools that can be translated successfully into industrial-scale systems. The automated ambr250® platform is one such technology, operating at a volume between 100 – 250mL and which is both high-throughput and single-use. The ambr250 has demonstrated significant success for suspension-based mammalian cell culture applications. However, no studies have been reported investigating microcarrier-based processes for the culture of adherent cells. With any cell culture process, the fluid dynamics characteristics of the bioreactor must be sufficiently well understood to enable successful scale-up to larger scale bioreactors. With microcarriers, there is an additional challenge as the fluid dynamics must take into account the presence of the particulate solid phase. A critical aspect for cell cultivation on microcarriers is the minimum agitator speed required to achieve complete microcarrier suspension, NJS. Under these conditions, the surface area of the attached cells is available for transfer of nutrients (including oxygen) to the cells and metabolites from them, whilst higher speeds hardly increase these transport processes and may lead to damaging fluid dynamic stresses being generated1. This suspension condition can be studied experimentally if equipment is specially modified to make easy visual observation of the two-phase flow in the bioreactor which during actual culture is very difficult. Therefore, it is extremely beneficial to both measure NJS and then to compare the measured values with predictions based on computational fluid dynamics (CFD) in order to validate the latter. Once validated, CFD modelling is a very useful tool for analysing flow patterns, mixing time, mean and local specific energy dissipation rates and other parameters important for scale up in order to optimise the overall bioreactor geometry. In addition to the above fluid dynamic aspects, cell culture studies was also performed in parallel to analyse the cell growth at and around the minimum speed for microcarrrier suspension, NJS and the results were compared to the culture performance in well-characterised traditional spinner flask bioreactors2.The CFD and experimental results with the single-use ambr250 bioreactor will be discussed in detail along with their scale-up implications. References 1. Nienow, A. W., Coopman, K., Heathman, T. R. J., Rafiq, Q. A. and C. J. Hewitt (2016). “Bioreactor Engineering Fundamentals for Stem Cell Manufacturing”. In: “Stem Cell Manufacturing”, (Eds. J.M.S. Cabral, C.L. de Silva, L. G. Chase and M. M. Diogo), Elsevier Science, Cambridge, USA; Chapter 3, pp 43 – 76. 2. Rafiq, Q. A., Brosnan, K. M., Coopman, K., Nienow, A. W. and Hewitt, C.J. (2013) Culture of Human Mesenchymal Stem Cells on Microcarriers in a 5 L Stirred-Tank Bioreactor. (with Q. A. Rafiq, K. M. Brosnan, K