Bar pattern speeds in CALIFA galaxies: I. Fast bars across the Hubble sequence

The bar pattern speed ($\Omega_{\rm b}$) is defined as the rotational frequency of the bar, and it determines the bar dynamics. Several methods have been proposed for measuring $\Omega_{\rm b}$. The non-parametric method proposed by Tremaine \& Weinberg (1984; TW) and based on stellar kinematics is the most accurate. This method has been applied so far to 17 galaxies, most of them SB0 and SBa types. We have applied the TW method to a new sample of 15 strong and bright barred galaxies, spanning a wide range of morphological types from SB0 to SBbc. Combining our analysis with previous studies, we investigate 32 barred galaxies with their pattern speed measured by the TW method. The resulting total sample of barred galaxies allows us to study the dependence of $\Omega_{\rm b}$ on galaxy properties, such as the Hubble type. We measured $\Omega_{\rm b}$ using the TW method on the stellar velocity maps provided by the integral-field spectroscopy data from the CALIFA survey. Integral-field data solve the problems that long-slit data present when applying the TW method, resulting in the determination of more accurate $\Omega_{\rm b}$. In addition, we have also derived the ratio $\cal{R}$ of the corotation radius to the bar length of the galaxies. According to this parameter, bars can be classified as fast ($\cal{R}$ $1.4). For all the galaxies,$\cal{R}$is compatible within the errors with fast bars. We cannot rule out (at 95$\%$level) the fast bar solution for any galaxy. We have not observed any significant trend between$\cal{R}$ and the galaxy morphological type. Our results indicate that independent of the Hubble type, bars have been formed and then evolve as fast rotators. This observational result will constrain the scenarios of formation and evolution of bars proposed by numerical simulations.Comment: 17 pages, 10 figures, accepted for publication in A&

Insights on the stellar mass-metallicity relation from the CALIFA survey

We use spatially and temporally resolved maps of stellar population properties of 300 galaxies from the CALIFA integral field survey to investigate how the stellar metallicity (Z*) relates to the total stellar mass (M*) and the local mass surface density ($\mu$*) in both spheroidal and disk dominated galaxies. The galaxies are shown to follow a clear stellar mass-metallicity relation (MZR) over the whole 10$^9$ to 10$^{12}$ M$_{\odot}$ range. This relation is steeper than the one derived from nebular abundances, which is similar to the flatter stellar MZR derived when we consider only young stars. We also find a strong relation between the local values of $\mu$* and Z* (the $\mu$ZR), betraying the influence of local factors in determining Z*. This shows that both local ($\mu$*-driven) and global (M*-driven) processes are important in determining the metallicity in galaxies. We find that the overall balance between local and global effects varies with the location within a galaxy. In disks, $\mu$* regulates Z*, producing a strong $\mu$ZR whose amplitude is modulated by M*. In spheroids it is M* who dominates the physics of star formation and chemical enrichment, with $\mu$* playing a minor, secondary role. These findings agree with our previous analysis of the star formation histories of CALIFA galaxies, which showed that mean stellar ages are mainly governed by surface density in galaxy disks and by total mass in spheroids.Comment: 6 pages, 3 figures, accepted for publication in ApJ

HST/WFPC2 imaging of the circumnuclear structure of LLAGNs. I Data and nuclear morphology

To advance our knowledge of the nature of the central source in LLAGNs and its relation with stellar clusters, we are carrying out several imaging projects with HST at near-UV, optical and near-IR wavelengths. In this paper, we present the first results obtained with observations of the central regions of 57 LLAGNs imaged with the WFPC2 through any of the V (F555W, F547M, F614W) and I (F791W, F814W) filters that are available in the HST archive. The sample contains 34% of the LINERs and 36% of the TOs in the Palomar sample. The mean spatial resolution of these images is 10 pc. With these data we have built an atlas that includes structural maps for all the galaxies, useful to identify compact nuclear sources and, additionally, to characterize the circumnuclear environment of LLAGNs, determining the frequency of dust and its morphology. The main results obtained are: 1) We have not found any correlation between the presence of nuclear compact sources and emission-line type. Thus, nucleated LINERs are as frequent as nucleated TOs. 2) The nuclei of "Young-TOs" are brighter than the nuclei of "Old-TOs" and LINERs. These results confirm our previous results that Young-TOs are separated from other LLAGNs classes in terms of their central stellar population properties and brightness. 3) Circumnuclear dust is detected in 88% of the LLAGNs, being almost ubiquitous in TOs. 4) The dust morphology is complex and varied, from nuclear spiral lanes to chaotic filaments and nuclear disk-like structures. Chaotic filaments are as frequent as dust spirals; but nuclear disks are mainly seen in LINERs. These results suggest an evolutionary sequence of the dust in LLAGNs, LINERs being the more evolved systems and Young-TOs the youngest. The full collection of figures are at http://www.iaa.es/~rosa/research/LLAGNs2007/LLAGNs-HSTIma1.htmlComment: Paper accepted in AJ, pdf file and the full collection of figures are at the ULR: http://www.iaa.es/~rosa/research/LLAGNs2007/LLAGNs-HSTIma1.htm

The Mass-Metallicity relation explored with CALIFA: I. Is there a dependence on the star formation rate?

We present the results on the study of the global and local M-Z relation based on the first data available from the CALIFA survey (150 galaxies). This survey provides integral field spectroscopy of the complete optical extent of each galaxy (up to 2-3 effective radii), with enough resolution to separate individual HII regions and/or aggregations. Nearly $\sim$3000 individual HII regions have been detected. The spectra cover the wavelength range between [OII]3727 and [SII]6731, with a sufficient signal-to-noise to derive the oxygen abundance and star-formation rate associated with each region. In addition, we have computed the integrated and spatially resolved stellar masses (and surface densities), based on SDSS photometric data. We explore the relations between the stellar mass, oxygen abundance and star-formation rate using this dataset. We derive a tight relation between the integrated stellar mass and the gas-phase abundance, with a dispersion smaller than the one already reported in the literature ($\sigma_{\Delta{\rm log(O/H)}}=$0.07 dex). Indeed, this dispersion is only slightly larger than the typical error derived for our oxygen abundances. However, we do not find any secondary relation with the star-formation rate, other than the one induced due to the primary relation of this quantity with the stellar mass. We confirm the result using the $\sim$3000 individual HII regions, for the corresponding local relations. Our results agree with the scenario in which gas recycling in galaxies, both locally and globally, is much faster than other typical timescales, like that of gas accretion by inflow and/or metal loss due to outflows. In essence, late-type/disk dominated galaxies seem to be in a quasi-steady situation, with a behavior similar to the one expected from an instantaneous recycling/closed-box model.Comment: 19 Pages, 8 figures, Accepted for Publishing in Astronomy and Astrophysics (A&A

Standard comparison of local mental health care systems in eight European countries

Aims. There is a need of more quantitative standardised data to compare local Mental Health Systems (MHSs) across international jurisdictions. Problems related to terminological variability and commensurability in the evaluation of services hamper like-with-like comparisons and hinder the development of work in this area. This study was aimed to provide standard assessment and comparison of MHS in selected local areas in Europe, contributing to a better understanding of MHS and related allocation of resources at local level and to lessen the scarcity in standard service comparison in Europe. This study is part of the Seventh Framework programme REFINEMENT (Research on Financing Systems’ Effect on the Quality of Mental Health Care in Europe) project. Methods. A total of eight study areas from European countries with different systems of care (Austria, England, Finland, France, Italy, Norway, Romania, Spain) were analysed using a standard open-access classification system (Description and Evaluation of Services for Long Term Care in Europe, DESDE-LTC). All publicly funded services universally accessible to adults (≥18 years) with a psychiatric disorder were coded. Care availability, diversity and capacity were compared across these eight local MHS. Results. The comparison of MHS revealed more community-oriented delivery systems in the areas of England (Hampshire) and Southern European countries (Verona – Italy and Girona – Spain). Community-oriented systems with a higher proportion of hospital care were identified in Austria (Industrieviertel) and Scandinavian countries (Sør-Trøndelag in Norway and Helsinki-Uusimaa in Finland), while Loiret (France) was considered as a predominantly hospital-based system. The MHS in Suceava (Romania) was still in transition to community care. Conclusions. There is a significant variation in care availability and capacity across MHS of local areas in Europe. This information is relevant for understanding the process of implementation of community-oriented mental health care in local areas. Standard comparison of care provision in local areas is important for context analysis and policy planning

Uncovering multiple Wolf-Rayet star clusters and the ionized ISM in Mrk 178: the closest metal-poor Wolf-Rayet H ii galaxy

New integral field spectroscopy (IFS) has been obtained for the nearby metal-poor Wolf–Rayet (WR) galaxy Mrk 178 to examine the spatial correlation between its WR stars and the neighbouring ionized interstellar medium (ISM). The strength of the broad WR features and its low metallicity make Mrk 178 an intriguing object. We have detected the blue and red WR bumps in different locations across the field of view (∼300 pc × 230 pc) in Mrk 178. The study of the WR content has been extended, for the first time, beyond its brightest star-forming knot uncovering new WR star clusters. Using Large/Small Magellanic Cloud-template WR stars, we empirically estimate a minimum of ∼20 WR stars within the region sampled. Maps of the spatial distribution of the emission lines and of the physical–chemical properties of the ionized ISM have been created and analysed. Here, we refine the statistical methodology by Pérez-Montero et al. (2011) to probe the presence of variations in the ISM properties. An error-weighted mean of 12+log(O/H) = 7.72 ± 0.01 is taken as the representative oxygen abundance for Mrk 178. A localized N and He enrichment, spatially correlated with WR stars, is suggested by this analysis. Nebular He II λ4686 emission is shown to be spatially extended reaching well beyond the location of the WR stars. This spatial offset between WRs and He II emission can be explained based on the mechanical energy input into the ISM by the WR star winds, and does not rule out WR stars as the He II ionization source. We study systematic aperture effects on the detection and measurement of the WR features, using Sloan Digital Sky Survey spectra combined with the power of IFS. In this regard, the importance of targeting low metallicity nearby systems is discussed

Stellar populations of bulges at low redshift

This chapter summarizes our current understanding of the stellar population properties of bulges and outlines important future research directions.Comment: Review article to appear in "Galactic Bulges", Editors: Laurikainen E., Peletier R., Gadotti D., Springer Publishing. 34 pages, 12 figure

Development of a Novel Anti-CD19 Chimeric Antigen Receptor : A Paradigm for an Affordable CAR T Cell Production at Academic Institutions

Genetically modifying autologous T cells to express an anti-CD19 chimeric antigen receptor (CAR) has shown impressive response rates for the treatment of CD19+ B cell malignancies in several clinical trials (CTs). Making this treatment available to our patients prompted us to develop a novel CART19 based on our own anti-CD19 antibody (A3B1), followed by CD8 hinge and transmembrane region, 4-1BB- and CD3z-signaling domains. We show that A3B1 CAR T cells are highly cytotoxic and specific against CD19+ cells in vitro, inducing secretion of pro-inflammatory cytokines and CAR T cell proliferation. In vivo, A3B1 CAR T cells are able to fully control disease progression in an NOD.Cg-Prkdc Il2rd/SzJ (NSG) xenograph B-ALL mouse model. Based on the pre-clinical data, we conclude that our CART19 is clearly functional against CD19+ cells, to a level similar to other CAR19s currently being used in the clinic. Concurrently, we describe the implementation of our CAR T cell production system, using lentiviral vector and CliniMACS Prodigy, within a medium-sized academic institution. The results of the validation phase show our system is robust and reproducible, while maintaining a low cost that is affordable for academic institutions. Our model can serve as a paradigm for similar institutions, and it may help to make CAR T cell treatment available to all patients

Response of phytoplankton to enhanced atmospheric and riverine nutrient inputs in a coastal upwelling embayment

Original research paperOver the past decades, as a consequence of human activity, there was an increase in nutrient inputs to the ocean and they are expected to enhance even more in the future. Coastal areas, accounting for a significant proportion of marine primary productivity, are the most vulnerable zones to anthropogenic impacts. The response of phytoplankton communities to an increase in organic and inorganic nutrients levels from natural allochthonous sources was assessed in microcosm experiments conducted in a coastal system affected by intermittent upwelling events (Ría de Vigo, NW Iberia). Three nutrient addition experiments were performed in spring, summer and autumn, when surface water was supplemented with 5 and 10% of atmospheric and riverine matter. Pico-, nano- and microphytoplankton abundances, chlorophyll a concentration (Chl a) and primary production rates (PP) were measured and compared with those in the control seawater sample (without additions) after 48 h of incubation. Simultaneous experiments with controlled additions of inorganic and organic nutrients were also performed in order to describe the limiting nutrient for phytoplankton growth at each experiment. The composition of the matter inputs and the structure of the phytoplankton communities determined the type of response observed. Phytoplankton responses varied among seasons, being positively correlated with dissolved inorganic nitrogen (DIN) concentrations. As expected, the phytoplankton responses to external nutrient inputs were stronger under low nutrient levels (summer) than when phytoplankton was already growing in nutrient replete conditions (spring). Null and negative responses to the natural inputs were observed in autumn, which suggests that the oceanic phytoplankton advected to this coastal system during downwelling events could be occasionally inhibited by these nutrient inputs. In a future global change scenario, characterized by enhanced nutrient inputs from riverine and atmospheric origin, the response of phytoplankton communities will strongly depend on the concentration and chemical composition of these inputs and on the structure of phytoplankton communities able to respond to themSpanish Ministry of Science and Innovation (project REIMAGE CTM2011-30155); Spanish Ministry of Economy and Competitiviness (project iSmall, reference CTM2014-56119-R); Portuguese Foundation for Science and Technology (reference SFRH/BPD/188485/2015); ESF (reference JAE DOC 040) and MINECO (project FERMIO reference CTM2014-57334-JIN)Versión del edito