153 research outputs found

    Attachment, couple communication and sexual coercion

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    Abstract : The use of subtle strategies to have sex with an unwilling partner is harmful to a couple’s sexual well-being but these strategies remain understudied. This research examined the mediating role of communication patterns in the associations between attachment insecurities and sustained sexual coercion in 145 same- and cross-gender couples, and the moderating role of partners’ gender. In addition to actor and partner effects, results revealed significant indirect effects from attachment insecurities to sexual coercion via communication patterns, with moderating effects of gender. Results may help practitioners and researchers understand the ways attachment insecurities and dysfunctional communication patterns can manifest in the experience of subtle forms of sexual coercion within couples

    PIXSIC: A Wireless Intracerebral Radiosensitive Probe in Freely Moving Rats

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    International audienceThe aim of this study was to demonstrate the potential of a wireless pixelated ÎČ+-sensitive intracerebral probe (PIXSIC) for in vivo positron emission tomographic (PET) radiopharmacology in awake and freely moving rodents. The binding of [ 11 C]raclopride to D 2 dopamine receptors was measured in anesthetized and awake rats following injection of the radiotracer. Competitive binding was assessed with a cold raclopride injection 20 minutes later. The device can accurately monitor binding of PET ligands in freely moving rodents with a high spatiotemporal resolution. Reproducible time-activity curves were obtained for pixels throughout the striatum and cerebellum. A significantly lower [ 11 C]raclopride tracer–specific binding was observed in awake animals. These first results pave the way for PET tracer pharmacokinetics measurements in freely moving rodents

    New insights on the population genetic structure of the great scallop (Pecten maximus) in the English Channel coupling microsatellite data and demogenetic simulations.

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    International audienceThe great scallop (Pecten maximus) is a commercially important bivalve in Europe, particularly in the English Channel, where fisheries are managed at regional and local scales through the regulation of fishing effort. In the long term, knowledge about larval dispersal and gene flow between populations is essential to ensure proper stock management. Yet, previous population genetic studies have reported contradictory results. In this study, scallop samples collected across the main fishing grounds along the French and English coasts of the English Channel (20 samples with temporal replicates for three sites,n= 1059 individuals), and the population genetic structure was analysed using 13 microsatellite loci. Coupling empirical genetic data with demogenetic modelling based on a biophysical model simulating larval exchanges among scallop beds revealed a subtle genetic differentiation between south-west English populations and the rest of the English Channel, which was consistent with larval dispersal simulations. The present study provides a step forward in the understanding of great scallop population biology in the English Channel, underlining the fact that even in a context of potentially high gene flow and recent divergence times since the end of the last glacial maximum, weak but significant spatial genetic structure can be identified at a regional scale

    COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

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    Background: The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms. Methods: International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms. Results: ‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≀ 18 years: 69, 48, 23; 85%), older adults (≄ 70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P < 0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country. Interpretation: This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men

    AltĂ©rations du discernement et troubles du neurodĂ©veloppement chez l’enfant et l’adolescent en contexte d’expertise psychiatrique pĂ©nale : revue de la littĂ©rature

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    Introduction : L’affaire AgnĂšs Marin, en 2011, a posĂ© un questionnement sur l’irresponsabilitĂ© pĂ©nale d’un adolescent prĂ©sentant des troubles des apprentissages. Dans cette affaire, Matthieu M. a violĂ©, maltraitĂ© puis tuĂ© AgnĂšs, une autre Ă©lĂšve de son Ă©tablissement. Quelques mois plus tĂŽt, il viole avec prĂ©mĂ©ditation une jeune fille de son village, selon le mĂȘme mode opĂ©ratoire, sans la tuer. Plusieurs expertises sont rĂ©alisĂ©es, mettant en avant des difficultĂ©s chez ce jeune homme sur le plan psychiatrique ; des dĂ©faillances au niveau du suivi sont Ă©galement mises en avant durant l’enquĂȘte, ainsi que des difficultĂ©s entre les diffĂ©rents intervenants pour s’échanger les informations nĂ©cessaires Ă  l’accompagnement du jeune. La question de l’irresponsabilitĂ© pĂ©nale est codifiĂ©e par l’article 122-1 du Code PĂ©nal mais pose question aujourd’hui. C'est pourquoi s’est constituĂ© le 24 juillet 2019, un groupe de travail1 commun sur l'expertise psychiatrique et psychologique en matiĂšre pĂ©nale, Ă  l'initiative de Nathalie Delattre et de Jean Sol. Les violences (sexuelles, physiques, psychologiques) sont une problĂ©matique majeure et largement sous-estimĂ©e dans notre sociĂ©tĂ©, en termes de criminalitĂ©, de consĂ©quences sur les victimes et de santĂ© publique. Notre rĂ©flexion va s’orienter sur le role de l’expertise psychiatrique dans le parcours judiciaire a des fins d’évaluation et de proposition de soins quand ils sont nĂ©cessaires
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