153 research outputs found
Attachment, couple communication and sexual coercion
Abstract : The use of subtle strategies to have sex with an unwilling partner is harmful to a coupleâs sexual well-being but these strategies remain understudied. This research examined the mediating role of communication patterns in the associations between attachment insecurities and sustained sexual coercion in 145 same- and cross-gender couples, and the moderating role of partnersâ gender. In addition to actor and partner effects, results revealed significant indirect effects from attachment insecurities to sexual coercion via communication patterns, with moderating effects of gender. Results may help practitioners and researchers understand the ways attachment insecurities and dysfunctional communication patterns can manifest in the experience of subtle forms of sexual coercion within couples
PIXSIC: A Wireless Intracerebral Radiosensitive Probe in Freely Moving Rats
International audienceThe aim of this study was to demonstrate the potential of a wireless pixelated ÎČ+-sensitive intracerebral probe (PIXSIC) for in vivo positron emission tomographic (PET) radiopharmacology in awake and freely moving rodents. The binding of [ 11 C]raclopride to D 2 dopamine receptors was measured in anesthetized and awake rats following injection of the radiotracer. Competitive binding was assessed with a cold raclopride injection 20 minutes later. The device can accurately monitor binding of PET ligands in freely moving rodents with a high spatiotemporal resolution. Reproducible time-activity curves were obtained for pixels throughout the striatum and cerebellum. A significantly lower [ 11 C]raclopride tracerâspecific binding was observed in awake animals. These first results pave the way for PET tracer pharmacokinetics measurements in freely moving rodents
New insights on the population genetic structure of the great scallop (Pecten maximus) in the English Channel coupling microsatellite data and demogenetic simulations.
International audienceThe great scallop (Pecten maximus) is a commercially important bivalve in Europe, particularly in the English Channel, where fisheries are managed at regional and local scales through the regulation of fishing effort. In the long term, knowledge about larval dispersal and gene flow between populations is essential to ensure proper stock management. Yet, previous population genetic studies have reported contradictory results. In this study, scallop samples collected across the main fishing grounds along the French and English coasts of the English Channel (20 samples with temporal replicates for three sites,n= 1059 individuals), and the population genetic structure was analysed using 13 microsatellite loci. Coupling empirical genetic data with demogenetic modelling based on a biophysical model simulating larval exchanges among scallop beds revealed a subtle genetic differentiation between south-west English populations and the rest of the English Channel, which was consistent with larval dispersal simulations. The present study provides a step forward in the understanding of great scallop population biology in the English Channel, underlining the fact that even in a context of potentially high gene flow and recent divergence times since the end of the last glacial maximum, weak but significant spatial genetic structure can be identified at a regional scale
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Monitoring bee health in European agroecosystems using wing morphology and fat bodies
Current global change substantially threatens pollinators, which directly impacts the
pollination services underpinning the stability, structure and functioning of ecosystems.
Amongst these threats, many synergistic drivers, such as habitat destruction and
fragmentation, increasing use of agrochemicals, decreasing resource diversity, as well as
climate change, are known to affect wild and managed bees. Therefore, reliable indicators
for pollinator sensitivity to such threats are needed. Biological traits, such as phenotype
(e.g. shape, size and asymmetry) and storage reserves (e.g. fat body size), are important
pollinator traits linked to reproductive success, immunity, resilience and foraging efficiency
and, therefore, could serve as valuable markers of bee health and pollination service
potential.
This data paper contains an extensive dataset of wing morphology and fat body content for
the European honeybee (Apis mellifera) and the buff-tailed bumblebee (Bombus terrestris)
sampled at 128 sites across eight European countries in landscape gradients dominated
by two major bee-pollinated crops (apple and oilseed rape), before and after focal crop
bloom and potential pesticide exposure. The dataset also includes environmental metrics
of each sampling site, namely landscape structure and pesticide use. The data offer the
opportunity to test whether variation in the phenotype and fat bodies of bees is structured
by environmental factors and drivers of global change. Overall, the dataset provides
valuable information to identify which environmental threats predominantly contribute to the
modification of these traits
COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study
Background:
The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms.
Methods:
International, prospective observational study of 60â109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms.
Results:
âTypicalâ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (â€â18 years: 69, 48, 23; 85%), older adults (â„â70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each Pâ<â0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country.
Interpretation:
This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men
AltĂ©rations du discernement et troubles du neurodĂ©veloppement chez lâenfant et lâadolescent en contexte dâexpertise psychiatrique pĂ©nale : revue de la littĂ©rature
Introduction : Lâaffaire AgnĂšs Marin, en 2011, a posĂ© un questionnement sur lâirresponsabilitĂ© pĂ©nale dâun adolescent prĂ©sentant des troubles des apprentissages. Dans cette affaire, Matthieu M. a violĂ©, maltraitĂ© puis tuĂ© AgnĂšs, une autre Ă©lĂšve de son Ă©tablissement. Quelques mois plus tĂŽt, il viole avec prĂ©mĂ©ditation une jeune fille de son village, selon le mĂȘme mode opĂ©ratoire, sans la tuer. Plusieurs expertises sont rĂ©alisĂ©es, mettant en avant des difficultĂ©s chez ce jeune homme sur le plan psychiatrique ; des dĂ©faillances au niveau du suivi sont Ă©galement mises en avant durant lâenquĂȘte, ainsi que des difficultĂ©s entre les diffĂ©rents intervenants pour sâĂ©changer les informations nĂ©cessaires Ă lâaccompagnement du jeune. La question de lâirresponsabilitĂ© pĂ©nale est codifiĂ©e par lâarticle 122-1 du Code PĂ©nal mais pose question aujourdâhui. C'est pourquoi sâest constituĂ© le 24 juillet 2019, un groupe de travail1 commun sur l'expertise psychiatrique et psychologique en matiĂšre pĂ©nale, Ă l'initiative de Nathalie Delattre et de Jean Sol. Les violences (sexuelles, physiques, psychologiques) sont une problĂ©matique majeure et largement sous-estimĂ©e dans notre sociĂ©tĂ©, en termes de criminalitĂ©, de consĂ©quences sur les victimes et de santĂ© publique. Notre rĂ©flexion va sâorienter sur le role de lâexpertise psychiatrique dans le parcours judiciaire a des fins dâĂ©valuation et de proposition de soins quand ils sont nĂ©cessaires
CĂ©ramiques du Ier siĂšcle de notre Ăšre dans le quartier d'Ancely (Toulouse, Haute-Garonne)
International audienc
Nurserie carcĂ©raleâ: processus de socialisation et enjeux sensoriels et psychomoteurs au sein dâun quartier «âmĂšre-enfantâ» pĂ©nitentiaire
International audienc
Quelle est la place du pharmacien d'officine dans l'éducation thérapeutique du patient diabétique de type II ?
LYON1-BU Santé (693882101) / SudocSudocFranceF
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