NASA Research Bearing on Jet Engine Reliability

Turbojet engine reliability has long been an intense interest to the military users of this type of aircraft propulsion. With the recent inauguration of commercial jet transport this subject has assumed a new dimension of importance. In January l96 the Lewis Research Center of the NASA (then the MACA) published the results of an extensive study on the factors that affect the opera- center dot tional reliability of turbojet engines (ref. 1). At that time the report was classified Confidential. In July l98 this report was declassified. It is thus appropriate at this time to present some of the highlights of the studies described in the NASA report. In no way is it intended to outline the complete contents of the report; rather it is hoped to direct attention to it among those who are center dot directly concerned with this problem. Since the publication of our study over three years ago, the NASA has completed a number of additional investigations that bear significantly on this center dot subject. A second object of this paper, therefore, is to summarize the results of these recent studies and to interpret their significance in relation to turbojet operational reliability

On the IYB-property in some solvable groups

A finite group G is called Involutive Yang-Baxter (IYB) if there exists a bijective 1-cocycle χ:G⟶M for some ZG -module M. It is known that every IYB-group is solvable, but it is still an open question whether the converse holds. A characterization of the IYB property by the existence of an ideal I in the augmentation ideal ωZG complementing the set 1−G leads to some speculation that there might be a connection with the isomorphism problem for ZG . In this paper we show that if N is a nilpotent group of class two and H is an IYB-group of order coprime to that of N, then N⋊H is IYB. The class of groups that can be obtained in that way (and hence are IYB) contains in particular Hertweck’s famous counterexample to the isomorphism conjecture as well as all of its subgroups. We then investigate what an IYB structure on Hertweck’s counterexample looks like concretely

Disinhibition of hippocampal CA3 neurons induced by suppression of an adenosine A1 receptor-mediated inhibitory tonus: Pre- and postsynaptic components

Intracellular recordings were performed on hippocampal CA3 neuronsin vitro to investigate the inhibitory tonus generated by endogenously produced adenosine in this brain region. Bath application of the highly selective adenosine A1 receptor antagonist 1,3-dipropyl-8-cyclopentylxanthine at concentrations up to 100 nM induced both spontaneous and stimulus-evoked epileptiform burst discharges. Once induced, the 1,3-dipropyl-8-cyclopentylxanthine-evoked epileptiform activity was apparently irreversible even after prolonged superfusion with drug-free solution. The blockade of glutamatergic excitatory synaptic transmission by preincubation of the slices with the amino-3-hydroxy-5-methyl-4-isoxazolpropionic acid receptor antagonist 6-cyano-7-nitroquinoxaline-2,3-dione (10 μM), but not with theN-methyl-d-aspartate receptor antagonistd-2-amino-5-phosphonovaleric acid (50/μM), prevented the induction of epileptiform activity by 1,3-dipropyl-8-cyclopentylxanthine. The generation of the burst discharges was independent of the membrane potential, and the amplitude of the slow component of the paroxysmal depolarization shift increased with hyperpolarization, indicating that the 1,3-dipropyl-8-cyclopentylxanthine-induced bursts were synaptically mediated events. Recordings from tetrodotoxin-treated CA3 neurons revealed a strong postsynaptic component of endogenous adenosinergic inhibition. Both 1,3-dipropyl-8-cyclopentylxanthine and the adenosine-degrading enzyme adenosine deaminase produced an apparently irreversible depolarization of the membrane potential by about 20 mV. Sometimes, this depolarization attained the threshold for the generation of putative calcium spikes, but no potential changes resembling paroxysmal depolarization shift-like events were observed

Nanoscale Evidence for Temperature-Induced Transient Rheology and Postseismic Fault Healing

Friction-generated heat and the subsequent thermal evolution control fault material properties and thus strength during the earthquake cycle. We document evidence for transient, nanoscale fault rheology on a high-gloss, light-reflective hematite fault mirror (FM). The FM cuts specularite with minor quartz from the Pleistocene El Laco Fe-ore deposit, northern Chile. Scanning and transmission electron microscopy data reveal that the FM volume comprises a2+ suboxides. Sub–5-nm-thick silica films encase hematite grains and connect to amorphous interstitial silica. Observations imply that coseismic shear heating (temperature \u3e1000 °C) generated transiently amorphous, intermixed but immiscible, and rheologically weak Fe-oxide and silica. Hematite regrowth in a fault-perpendicular thermal gradient, sintering, twinning, and a topographic network of nanometer-scale ridges from crystals interlocking across the FM surface collectively restrengthened fault material. Results reveal how temperature-induced weakening preconditions fault healing. Nanoscale transformations may promote subsequent strain delocalization and development of off-fault damage

Boric acid vaginal suppositories: a brief review.

OBJECTIVE: The purpose of this study was to determine the utility of serum CA125 determinations in diagnosing acute salpingitis. METHODS: CA125 levels were determined for 34 women with the clinical diagnosis of pelvic inflammatory disease (PID). Acute salpingitis was confirmed laparoscopically in 28 women (82.3%). RESULTS: Twenty patients (71.4%) with laparoscopically confirmed acute salpingitis had CA125 levels greater than 7.5 units, compared with no patients (0/6) with laparoscopically normal tubes (P = 0.002). The degree of elevation of CA125 levels correlated with the severity of tubal inflammation noted at laparoscopy. All patients with levels above 16 units had laparoscopically severe salpingitis. CONCLUSIONS: We conclude that while CA125 levels above 7.5 units may modestly improve the ability of the clinical diagnosis of PID to accurately reflect visually confirmed acute salpingitis, limitations of the test make its clinical utility questionable

Revisiting the design intent concept in the context of mechanical CAD education

[EN] Design intent is generally understood simply as a CAD model¿s anticipated behavior when altered. However, this representation provides a simplified view of the model¿s construction and purpose, which may hinder its general understanding and future reusability. Our vision is that design intent communication may be improved by recognizing the multifaceted nature of design intent, and by instructing users to convey each facet of design intent through the better-fitted CAD resource. This paper reviews the current understanding of design intent and its relationship to design rationale and builds on the idea that communication of design intent conveyed via CAD models can be satisfied at three levels provided that specialized instruction is used to instruct users in selection of the most suitable level for each intent.Otey, J.; Company, P.; Contero, M.; Camba, J. (2018). Revisiting the design intent concept in the context of mechanical CAD education. Computer-Aided Design and Applications. 15(1):47-60. https://doi.org/10.1080/16864360.2017.1353733S476015