IDR/UPM facilities for liquid bridge experimentation on earth under microgravity conditions

Besides space laboratories for in-orbit experimentation, Earth based facilities for laboratory experimentation are of paramount importance for the enhancement on liquid bridge knowledge. In spite of the constraints imposed by simulated microgravity (which force to work either with very small size liquid bridges or by using the Plateau tank technique, amongst other techniques), the availability and accessibility of Earth facilities can circumvent in many cases the drawbacks associated with simulated microgravity conditions. To support theoretical and in orbit experimental studies on liquid bridges under reduced gravity conditions, several ground facilities were developed at IDR. In the following these ground facilities are briefly described, and main results obtained by using them are cited

Minimum volume of long liquid bridges between noncoaxial, nonequal diameter circular disks under lateral acceleration

The stability limit of minimum volume and the breaking dynamics of liquid bridges between nonequal, noncoaxial, circular supporting disks subject to a lateral acceleration were experimentally analyzed by working with liquid bridges of very small dimensions. Experimental results are compared with asymptotic theoretical predictions, with the agreement between experimental results and asymptotic ones being satisfactor

Electromagnetic transitions of the helium atom in superstrong magnetic fields

We investigate the electromagnetic transition probabilities for the helium atom embedded in a superstrong magnetic field taking into account the finite nuclear mass. We address the regime \gamma=100-10000 a.u. studying several excited states for each symmetry, i.e. for the magnetic quantum numbers 0,-1,-2,-3, positive and negative z parity and singlet and triplet symmetry. The oscillator strengths as a function of the magnetic field, and in particular the influence of the finite nuclear mass on the oscillator strengths are shown and analyzed.Comment: 10 pages, 8 figure

Estimation of the tectonic slip-rate from Quaternary lacustrine facies within the intraplate Albacete province (SE of Spain)

The Quaternary lacustrine basin of Cordovilla (CB) represents one of the most active tectonic areas of the Prebetic Zone (Albacete, SE of Spain). The Quaternary sedimentary deposits of this basin are mainly endoreic lacustrine carbonate and alluvial deposits, developed in a semi-arid climate (Pleistocene-present). The basin is a NW–SE-elongated graben bounded by a major right-lateral oblique-fault, the Pozohondo Fault. This fault trendsNW–SE, with an approximate trace of 55 km, and is composed of various segments which are identified by fault scarps. In order to establish the slip-rate of the most active segment of the Pozohondo Fault, called the Cordovilla segment, we carried out a detailed study of the affected Quaternary lacustrine deposits. We found that the lacustrine facies could be related to episodic moderate paleoearthquakes. The slip-rate is calculated to be 0.05 and 0.09 mm/yr, using radiometric dating for the vertical offsets of the lacustrine facies. A trenching study at the northern part of the Cordovilla segment revealed two events caused by paleoearthquakes, with the most recent expressed as an oblique-fault off-setting a poorly-developed soil. The magnitude of the last event was greater than 6, using various empirical relationships for the fault displacement and the surface-length rupture. We estimate episodic activity across the Cordovilla segment, to be characterized by moderate-sized paleoearthquakes (M6), which is in agreement with the tectonic context of an intraplate zone of the Iberian plate

Respuesta de hongos benéficos del suelo asociados a Lotus tenuis a la aplicación de glifosato

En los últimos años se está adoptando la práctica de promoción de Lotus tenuis a través de la aplicación de glifosato en pastizales de La Pampa Deprimida debido a su importante aporte en cantidad y calidad de forraje. Sin embargo, diversos estudios han demostrado que el uso de este herbicida puede ocasionar efectos no deseados en microorganismos benéficos del suelo. El objetivo de este trabajo fue evaluar el efecto de la aplicación de glifosato sobre los hongos micorrícicos arbusculares y hongos septados oscuros asociados a L. tenuis. En una pastura de L. tenuis se establecieron dos tratamientos: Lotus tenuis promovido y Lotus tenuis establecido. En el primer caso, la pastura se pulverizó en invierno (fines de agosto) con 3,5 l/ha de glifosato, mientras en el segundo tratamiento la pastura de L. tenuis no recibió la aplicación del herbicida. Los resultados demuestran que el número de esporas viables de hongos micorrícicos arbusculares fue un 52% menor, y el porcentaje de arbúsculos en plantas de L. tenuis un 40% menor, en el tratamiento Lotus tenuis promovido en relación con el tratamiento Lotus tenuis establecido. La colonización radical por hongos septados oscuros no fue afectada por la aplicación de glifosato. La pérdida de funcionalidad de la simbiosis micorrícica podría en el mediano plazo afectar no solo la producción de biomasa de L. tenuis, sino también la diversidad y productividad de todas las especies presentes en la comunidad vegetal. La información generada en este trabajo será de utilidad para rediseñar prácticas de manejo que permitan la producción de alimento con un uso sustentable de los recursos.In recent years, the Lotus tenuis promotion through glyphosate application has been adopted in Flooding Pampa grasslands, due to the important contribution in forage quantity and quality of this species. However, several studies have shown that the use of glyphosate can cause undesirable effects on beneficial soil microorganisms. The objective of this study was to evaluate the effect of glyphosate application on the arbuscular mycorrhizal fungi and dark septate endophytes associated to L. tenuis. Two treatments were applied in plots located in a L. tenuis pasture: promoted Lotus tenuis and established Lotus tenuis. In the first case, plots were sprayed in winter (late August) with 3.5 l/ha of glyphosate, while in the second treatment plots did not receive herbicide application. Our results demonstrated that the number of viable spores of arbuscular mycorrhizal fungi was 52% lower, and the percentage of arbuscules in L. tenuis plants was 40% lower in the Promoted Lotus tenuis treatment in relation to Established Lotus tenuis treatment. Root colonization by dark septate endophytes was not affected by glyphosate application. The loss of functionality of the mycorrhizal symbiosis might in the medium-term affect not only L. tenuis biomass production, but also the diversity and productivity of the complete plant community. The information generated in this study will be useful to redesign management practices that allow food production with a sustainable use of resources.EEA Cuenca del SaladoFil: Druille, Magdalena. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal; ArgentinaFil: Acosta, A. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal; ArgentinaFil: Acosta, G. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal; ArgentinaFil: Rossi, J.L. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal; ArgentinaFil: Golluscio, Rodolfo A. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal; ArgentinaFil: Bailleres, Matias Andres. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Cuenca del Salado. Agencia de Extensión Rural Chascomus; Argentin

Helium in superstrong magnetic fields

We investigate the helium atom embedded in a superstrong magnetic field gamma=100-10000 au. All effects due to the finite nuclear mass for vanishing pseudomomentum are taken into account. The influence and the magnitude of the different finite mass effects are analyzed and discussed. Within our full configuration interaction approach calculations are performed for the magnetic quantum numbers M=0,-1,-2,-3, singlet and triplet states, as well as positive and negative z parities. Up to six excited states for each symmetry are studied. With increasing field strength the number of bound states decreases rapidly and we remain with a comparatively small number of bound states for gamma=10^4 au within the symmetries investigated here.Comment: 16 pages, including 14 eps figures, submitted to Phys. Rev.

A Search for Rapid Photometric Variability in Symbiotic Binaries

We report on our survey for rapid (time scale of minutes) photometric variability in symbiotic binaries. These binaries are becoming an increasingly important place to study accretion onto white dwarfs since they are candidate Type Ia supernovae progenitors. Unlike in most cataclysmic variables, the white dwarfs in symbiotics typically accrete from a wind, at rates greater than or equal to 10^{-9} solar masses per year. In order to elucidate the differences between symbiotics and other white dwarf accretors, as well as search for magnetism in symbiotic white dwarfs, we have studied 35 primarily northern symbiotic binaries via differential optical photometry. Our study is the most comprehensive to date of rapid variability in symbiotic binaries. We have found one magnetic accretor, Z And, previously reported by Sokoloski & Bildsten (1999). In four systems (EG And, BX Mon, CM Aql, and BF Cyg), some evidence for flickering at a low level (roughly 10 mmag) is seen for the first time. These detections are, however, marginal. For 25 systems, we place tight upper limits (order of mmag) on both aperiodic and periodic variability, highlighting a major difference between symbiotics and cataclysmic variables. The remaining five of the objects included in our sample (the 2 recurrent novae RS Oph and T CrB, plus CH Cyg, o Ceti, and MWC 560) had previous detections of large-amplitude optical flickering, and we present our extensive observations of these systems in a separate paper. We discuss the impact of our results on the ``standard'' picture of wind-fed accretion, and speculate on the possibility that in most symbiotics, light from quasi-steady nuclear burning on the surface of the white dwarf hides the fluctuating emission from accretion.Comment: 24 pages, 17 figures. Submitted to MNRAS (12/21/00), and revised in response to referee comments (3/30/01

Elementary landscape decomposition of the 0-1 unconstrained quadratic optimization

Journal of Heuristics, 19(4), pp.711-728Landscapes’ theory provides a formal framework in which combinatorial optimization problems can be theoretically characterized as a sum of an especial kind of landscape called elementary landscape. The elementary landscape decomposition of a combinatorial optimization problem is a useful tool for understanding the problem. Such decomposition provides an additional knowledge on the problem that can be exploited to explain the behavior of some existing algorithms when they are applied to the problem or to create new search methods for the problem. In this paper we analyze the 0-1 Unconstrained Quadratic Optimization from the point of view of landscapes’ theory. We prove that the problem can be written as the sum of two elementary components and we give the exact expressions for these components. We use the landscape decomposition to compute autocorrelation measures of the problem, and show some practical applications of the decomposition.Spanish Ministry of Sci- ence and Innovation and FEDER under contract TIN2008-06491-C04-01 (the M∗ project). Andalusian Government under contract P07-TIC-03044 (DIRICOM project)

Randomized crossover pharmacokinetic evaluation of subcutaneous versus intravenous granisetron in cancer patients treated with platinum-based chemotherapy

BACKGROUND: 5-HT3-receptor antagonists are one of the mainstays of antiemetic treatment, and they are administered either i.v. or orally. Nevertheless, sometimes neither administration route is feasible, such as in patients unable to admit oral intake managed in an outpatient setting. Our objective was to evaluate the bioavailability of s.c. granisetron. PATIENTS AND METHODS: Patients receiving platinum-based chemotherapy were randomized to receive 3 mg of granisetron either s.c. or i.v. in a crossover manner during two cycles. Blood and urine samples were collected after each cycle. Pharmacokinetic parameters observed with each administration route were compared by analysis of variance. RESULTS: From May to November 2005, 31 patients were included and 25 were evaluable. Subcutaneous granisetron resulted in a 27% higher area under the concentration-time curve for 0-12 hours (AUC(0-12h)) and higher levels at 12 hours, with similar values for AUC(0-24h). The maximum concentration was lower with the s.c. than with the i.v. route and was observed 30 minutes following s.c. administration. CONCLUSION: Granisetron administered s.c. achieves complete bioavailability. This is the first study that shows that s.c. granisetron might be a valid alternative to i.v. delivery. Further trials to confirm clinical equivalence are warranted. This new route of administration might be especially relevant for outpatient management of emesis in cancer patients

Dynamic relationships between body fat and circulating adipokine levels from adolescence to young adulthood: The Santiago Longitudinal Study

Background and aims: Adipose tissue secretes adipokines such as adiponectin and leptin, playing important roles in energy metabolism. The longitudinal associations between such adipokines and body fat accumulation have not been established, especially during adolescence and young adulthood and in diverse populations. The study aims to assess the longitudinal association between body fat measured with dual X-ray absorptiometry and plasma adipokines from adolescence to young adulthood. Methods and results: Among Hispanic/Latino participants (N = 537) aged 16.8 (SD: 0.3) years of the Santiago Longitudinal Study, we implemented structural equation modeling to estimate the sex-specific associations between adiposity (body fat percent (BF%) and proportion of trunk fat (PTF)) and adipokines (adiponectin and leptin levels) during adolescence (16 y) and these values after 6 years of follow-up (22 y). In addition, we further investigated whether the associations differed by baseline insulin resistance (IR) status. We found evidence for associations between 16 y BF% and 22 y leptin levels (β (SE): 0.58 (0.06) for females; 0.53 (0.05) for males), between 16 y PTF and 22 y adiponectin levels (β (SE): −0.31 (0.06) for females; −0.18 (0.06) for males) and between 16 y adiponectin levels and 22 y BF% (β (SE): 0.12 (0.04) for both females and males). Conclusion: We observed dynamic relationships between adiposity and adipokines levels from late adolescence to young adulthood in a Hispanic/Latino population further demonstrating the importance of this period of the life course in the development of obesity