25,683 research outputs found
An ALMA study of the Orion Integral Filament : I. Evidence for narrow fibers in a massive cloud
© 2018 ESO. Reproduced with permission from Astronomy & Astrophysics. Content in the UH Research Archive is made available for personal research, educational, and non-commercial purposes only. Unless otherwise stated, all content is protected by copyright, and in the absence of an open license, permissions for further re-use should be sought from the publisher, the author, or other copyright holder.Aim. We have investigated the gas organization within the paradigmatic Integral Shape Filament (ISF) in Orion in order to decipher whether or not all filaments are bundles of fibers. Methods. We combined two new ALMA Cycle 3 mosaics with previous IRAM 30m observations to produce a high-dynamic range N 2H + (1-0) emission map of the ISF tracing its high-density material and velocity structure down to scales of 0.009 pc (or ~2000 AU). Results. From the analysis of the gas kinematics, we identify a total of 55 dense fibers in the central region of the ISF. Independently of their location in the cloud, these fibers are characterized by transonic internal motions, lengths of ~0.15 pc, and masses per unit length close to those expected in hydrostatic equilibrium. The ISF fibers are spatially organized forming a dense bundle with multiple hub-like associations likely shaped by the local gravitational potential. Within this complex network, the ISF fibers show a compact radial emission profile with a median FWHM of 0.035 pc systematically narrower than the previously proposed universal 0.1 pc filament width. Conclusions. Our ALMA observations reveal complex bundles of fibers in the ISF, suggesting strong similarities between the internal substructure of this massive filament and previously studied lower-mass objects. The fibers show identical dynamic properties in both low- and high-mass regions, and their widespread detection in nearby clouds suggests a preferred organizational mechanism of gas in which the physical fiber dimensions (width and length) are self-regulated depending on their intrinsic gas density. Combining these results with previous works in Musca, Taurus, and Perseus, we identify a systematic increase of the surface density of fibers as a function of the total mass per-unit-length in filamentary clouds. Based on this empirical correlation, we propose a unified star-formation scenario where the observed differences between low- and high-mass clouds, and the origin of clusters, emerge naturally from the initial concentration of fibers.Peer reviewedFinal Published versio
Signals for New Spin-1 Resonances in Electroweak Gauge Boson Pair Production at the LHC
The mechanism of electroweak symmetry breaking (EWSB) will be directly
scrutinized soon at the CERN Large Hadron Collider (LHC). We analyze the LHC
potential to look for new vector bosons associated with the EWSB sector. We
present a possible model independent approach to search for these new spin--1
resonances. We show that the analyses of the processes pp --> l^+ l^- Emiss_T,
l^\pm j j Emiss_T, l^\pm l^+ l^- Emiss_T, and l^+ l^- j j (with l=e or \mu and
j=jet) have a large reach at the LHC and can lead to the discovery or exclusion
of many EWSB scenarios such as Higgsless models.Comment: 10 pages, 11 figure
Human case of West Nile neuroinvasive disease in Portugal, summer 2015
A case of West Nile virus (WNV) infection was reported in the Algarve region, Portugal, in the first week of September 2015. WNV is known to circulate in Portugal, with occasional reports in horses and birds (2004 to 2011) and very sporadically human cases (in 2004 and in 2010). Here we present the clinical and laboratory aspects related to the first human case of West Nile neuroinvasive disease reported in Portugal
Extended-release niacin increases anti-apolipoprotein A-I antibodies that block the antioxidant effect of high-density lipoprotein-cholesterol: the EXPLORE clinical trial.
Extended-release niacin (ERN) is the most effective agent for increasing high-density lipoprotein-cholesterol (HDL-C). Having previously identified anti-HDL antibodies, we investigated whether ERN affected the antioxidant capacity of HDL and whether ERN was associated with the production of antibodies against HDL (aHDL) and apolipoprotein A-I (aApoA-I).
METHODS:
Twenty-one patients older than 18 years, with HDL-C ≤40 mg dl-1 (men) or ≤50 mg dl-1 (women) were randomly assigned to receive daily ERN (n = 10) or placebo (n = 11) for two sequential 12-week periods, with 4 weeks of wash-out before cross-over. Primary outcome was change of paraoxonase-1 (PON1) activity and secondary outcomes were changes in aHDL and aApoA-I antibodies. Clinical Trial Unique Identifier: EudraCT 2006-006889-42.
RESULTS:
The effect of ERN on PON1 activity was nonsignificant (coefficient estimate 20.83 U l-1 , 95% confidence interval [CI] -9.88 to 51.53; P = 0.184). ERN was associated with an increase in HDL-C levels (coefficient estimate 5.21 mg dl-1 , 95% CI 1.16 to 9.25; P = 0.012) and its subclasses HDL2 (coefficient estimate 2.46 mg dl-1 , 95% CI 0.57 to 4.34; P = 0.011) and HDL3 (coefficient estimate 2.73 mg dl-1 , 95% CI 0.47 to 4.98; P = 0.018). ERN was significantly associated with the production of aApoA-I antibodies (coefficient estimate 0.25 μg ml-1 , 95% CI 0.09-0.40; P = 0.001). aApoA-I titres at baseline were correlated with decreased PON activity.
CONCLUSIONS:
The rise in HDL-C achieved with ERN was not matched by improved antioxidant capacity, eventually hampered by the emergence of aApoA-I antibodies. These results may explain why Niacin and other lipid lowering agents fail to reduce cardiovascular risk.info:eu-repo/semantics/publishedVersio
Amplification and generation of ultra-intense twisted laser pulses via stimulated Raman scattering
Twisted Laguerre-Gaussian lasers, with orbital angular momentum and
characterised by doughnut shaped intensity profiles, provide a transformative
set of tools and research directions in a growing range of fields and
applications, from super-resolution microcopy and ultra-fast optical
communications to quantum computing and astrophysics. The impact of twisted
light is widening as recent numerical calculations provided solutions to
long-standing challenges in plasma-based acceleration by allowing for high
gradient positron acceleration. The production of ultrahigh intensity twisted
laser pulses could then also have a broad influence on relativistic
laser-matter interactions. Here we show theoretically and with ab-initio
three-dimensional particle-in-cell simulations, that stimulated Raman
backscattering can generate and amplify twisted lasers to Petawatt intensities
in plasmas. This work may open new research directions in non-linear optics and
high energy density science, compact plasma based accelerators and light
sources.Comment: 18 pages, 4 figures, 1 tabl
Why is timing of bird migration advancing when individuals are not?
Recent advances in spring arrival dates have been reported in many migratory species but the mechanism driving these advances is unknown. As population declines are most widely reported in species that are not advancing migration, there is an urgent need to identify the mechanisms facilitating and constraining these advances. Individual plasticity in timing of migration in response to changing climatic conditions is commonly proposed to drive these advances but plasticity in individual migratory timings is rarely observed. For a shorebird population that has significantly advanced migration in recent decades, we show that individual arrival dates are highly consistent between years, but that the arrival dates of new recruits to the population are significantly earlier now than in previous years. Several mechanisms could drive advances in recruit arrival, none of which require individual plasticity or rapid evolution of migration timings. In particular, advances in nest-laying dates could result in advanced recruit arrival, if benefits of early hatching facilitate early subsequent spring migration. This mechanism could also explain why arrival dates of short-distance migrants, which generally return to breeding sites earlier and have greater scope for advance laying, are advancing more rapidly than long-distance migrants
Optical doping and damage formation in AIN by Eu implantation
AlN films grown on sapphire were implanted with 300 keV Eu ions to fluences from 3×1014 to 1.4×1017 atoms/cm2 in two different geometries: “channeled” along the c-axis and “random” with a 10° angle between the ion beam and the surface normal. A detailed study of implantation damage accumulation is presented. Strong ion channeling effects are observed leading to significantly decreased damage levels for the channeled implantation within the entire fluence range. For random implantation, a buried amorphous layer is formed at the highest fluences. Red Eu-related photoluminescence at room temperature is observed in all samples with highest intensities for low damage samples (low fluence and channeled implantation) after annealing. Implantation damage, once formed, is shown to be stable up to very high temperatures.FCT - POCI/FIS/57550/2004FCT - PTDC/FIS/66262/2006FCT - PTDC/CTM/100756/200
3D gravity and non-linear cosmology
By the inclusion of an additional term, non-linear in the scalar curvature
, it is tested if dark energy could rise as a geometrical effect in 3D
gravitational formulations. We investigate a cosmological fluid obeying a
non-polytropic equation of state (the van der Waals equation) that is used to
construct the energy-momentum tensor of the sources, representing the
hypothetical inflaton in gravitational interaction with a matter contribution.
Following the evolution in time of the scale factor, its acceleration, and
the energy densities of constituents it is possible to construct the
description of an inflationary 3D universe, followed by a matter dominated era.
For later times it is verified that, under certain conditions, the non-linear
term in can generate the old 3D universe in accelerated expansion, where
the ordinary matter is represented by the barotropic limit of the van der Waals
constituent.Comment: 7 pages, to appear in Mod. Phys. Let
<i>Schistosoma mansoni</i> cercariae experience influx of macromolecules during skin penetration
We have observed that when cercariae penetrate the skin of mice, there is influx into their tissues of Lucifer Yellow and certain labelled molecules of up to 20 kDa molecular weight. This observation was made using a variety of fluorescent membrane-impermeant compounds injected into the skin before the application of cercariae. This unexpected phenomenon was investigated further by transforming cercariae in vitro in the presence of the membrane-impermeant compounds and examining the distribution by microscopy. In schistosomula derived from this procedure, the nephridiopore and surface membrane were labelled while the pre- and post-acetabular glands were not labelled. The region associated with the oesophagus within the pharyngeal muscle clearly contained the fluorescent molecules, as did the region adjacent to the excretory tubules and the germinal mass. We used cercariae stained with carmine to aid identification of regions labelled with Lucifer Yellow. Although the mechanism of this influx is unclear, the observation is significant. From it, we can suggest an hypothesis that, during skin penetration, exposure of internal tissues of the parasite to external macromolecules represents a novel host-parasite interfac
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