Hospital Prof. Dr. Fernando Fonseca
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Cardioneuroablation: a new era for vagal syncope?
42 years old male athlete
Bradycardia and vagal syncope episodes
ECGs showed sinus rhythm with bradycardia (40-44 bpm)
Transthoracic Echocardiogram: normal
TILT test: positive - 2b cardio inhibitory response and 20s asystoleN/
AVALIAÇÃO DO FEV1Q COMO PREDITOR DE MORTALIDADE NA ESCLEROSE LATERAL AMIOTRÓFICA: EXPERIÊNCIA DE UM HOSPITAL DISTRITAL
Num período de cerca de 6 anos verificou-se uma importante mortalidade nos doentes com ELA;
O FEV1Q revelou-se o melhor preditor de mortalidade de entre as variáveis analisadas;
instabilidade poderá corresponder a um agravamento progressivo da ELA.
Antes de aplicar estes resultados na prática clínica, é essencial realizar esta análise numa população maior para validar sua relevância e precisão.N/
An inverted puzzle: a complex case of CRT in a congenitally corrected transposition of great vessels
TTE: congenitally corrected transposition of great vessels (ccTGA) and a dextrocardia; suspicion of ventricular septal defect (VSD; severely depressed left ventricular function (ejection fraction < 30%)
Heart CT scan: confirmation of CCTGA and dextrocardiaN/
8-ZONE LUNG ULTRASOUND AND BIOIMPEDANCE ANALYSIS FOR ASSESSMENT OF HYDRATION STATUS IN HEMODIALYSIS
The 8-zone Lung US protocol is efficient to evaluate patients prior to HD sessions.
There is a good correlation between the total number of B lines determined by the 8-zone protocol and bioimpedance parameters such as TBW, ECW, and normalized OH.
This demonstrates that the 8-zone protocol can effectively be used in routine evaluations of HD patients. Although these techniques reflect different over-fluid compartments, they have a complementary role for fluid overload determination and dry weight guidance.N/
DIAGNOSTIC - challeng
Neste caso, a marcha diagnóstica consistiu na exclusão de causa neoplásica com a realização de TC de corpo, toracocentese e exames endoscópicos
A biópsia do duodeno foi primordial para estabelecer o diagnóstico atempado de Doença de Whipple com identificação do bacilo Tropheryma whippleiN/
RESULTS FROM A 48-WEEK PHASE 2 STUDY
Database solution for an HIV-2 cohort study
Publication "Real-world experience of TAF/FTC/BIC in people with HIV-2" presented at European AIDS Clinical Society Conference, Oct 2023, Warsaw
HIV-2 salvage therapy with Lenacapavir (injectable, capsid inhibitor, EMA approved 2022)N/
ARC-HBR SCORE PREDICTS BETTER THAN HAS-BLED THE RISK OF MAJOR BLEEDING IN PATIENTS WITH ATRIAL FIBRILLATION
Neste estudo unicêntrico retrospetivo com doentes hospitalizados por fibrilhação auricular, o score ARC-HBR critérios major tem um desempenho superior ao HAS-BLED e semelhante ao HEMORR2HAGES na previsão do risco de hemorragiaN/
first report of two combined mutational variants in a Portuguese patient
WD is rare, and the diagnostic suspicion should be high in young patients with subacute or acute chronic liver disease: a diagnosis made in time can avoid a liver transplant.
The diagnostic workup was not straightforward, and genetic testing was necessary to confirm the diagnosis
To our knowledge, this is the first report of this compound heterozygote genotype.
The c.3402del mutation has been described as liver-predominant in heterozygous and neurologically predominant in homozygous patients.
The c.3061-12T>A mutation is described as neurologically predominant.
The evolution of our patient remains to be seen in the long-term follow-up.N/
PrOgnosis in Pulmonary Embolism (PoPE): 30-day mortality risk score based on five admission parameters
Existem vários sistemas de pontuação para a estratificação de doentes com tromboembolismo pulmonar (TEP).
As taxas de mortalidade no TEP agudo dependem principalmente da gravidade da disfunção cardiopulmonar na apresentação e das comorbidades associadas.N/
UNVEILING THE UNUSUAL: A RARE CASE OF TRANSIENT CARDIOMYOPATHY IN A YOUNG MALE
Há alguns casos descritos na literatura de insuficiência da supra renal como causa reversível de disfunção ventricular esquerda;
O vasospasmo coronário está associado a défice de corticosteroides;
A combinação de hipocortisolismo com doença arterial coronária aterosclerótica é raro (inflamação acelerada?);
Este caso ilustra a importância de procurar causas reversíveis de disfunção ventricular esquerda.N/