Ön Gerilmeli Piezoelektrik Örtü Tabakası Ve Ön Gerilmeli Elastik Yarı Düzlemden Oluşan Sistemde Genelleştirilmiş Rayleigh Dalgalarının Dispersiyonu

Konferans Bildirisi -- Teorik ve Uygulamalı Mekanik Türk Milli Komitesi, 2013Conference Paper -- Theoretical and Applied Mechanical Turkish National Committee, 2013Bu çalışmada doğrusallaştırılmış dalga teorisi kullanılarak ön gerilmeli piezoelektrik tabaka ile örtülü ön gerilmeli yarı düzlem ortamında genelleştirilmiş Rayleigh dalgalarının dispersiyonu incelenmiştir.In this paper, generalized Rayleigh wave dispersion in a pre-stressed half-plane covered with a pre-stressed piezoelectric layer is studied using linearized wave theory

Formulation of a mathematical problem and methods for solving the development of antistatic clothing for protection from elevated temperatures

The article is devoted to the study and development of a mathematical model of the process of electrification of textile materials in the system "man - clothing - environment" in hot climatic conditions. The phenomenon of static electrification, which occurs in the processes of manufacturing textile materials and products from them, as well as during the operation of finished products, leads to a decrease in the quality of products, causes inconvenience in work, and when an electric discharge occurs, it poses a threat to human life. Such interactions of elements in the "person - clothing - environment" system such as friction, compression, tension, shear increase the contact area of two media, and depending on the rate of these processes, they enhance or weaken metabolic processes, which contributes to an increase in the maximum static charge generated on contacting surfaces. temperature values for special clothing of limited length at the nodal points. At the same time, the number of nodal points is 1601, the number of connected elements is 800. In the area of temperature distribution along the length of the garment, in four different versions, it was found that in the I – version , in the II – version  , in the III – version , in the IV – version , in the V – version , in the VI - version, the length of the clothes in this area increased by 10% compared to the length of the clothes in the II – version

Assessment of information value of targeted biopsy and endoscopic removal of colorectal polyps

This research is based on histological investigation of targeted biopsy material and resected polyps’ at 354 patients who applied to National Center of Oncology from 2005 to 2010. All patients underwent targeted biopsy at first with subsequent endoscopic polypectomy and 494 polyps were removed and histologically investigated. The most prevalence type was tubular polyp — 212 (43 %) cases. The rest types of polyps were distributed as follow: tubule-villous type — 125 (25.3 %), villous type — 16 (3.2 %), inflammatory type — 28 (5.7 %), hyperplastic type — 40 (8.1 %), hamartoma type — 21 (4.3 %) cases. In 52 (10.4 %) cases malignant polyps were revealed.Sensitivity of targeted biopsy in iagnostics of dysplasia was 65.1 % while in revealing of malignancy was even lower — just 36.5 %. So we consider performing of endoscopic polypectomy and histological evaluation of resected polyps in all case even after previous targeted biopsy

Primary care medication safety surveillance with integrated primary and secondary care electronic health records: a cross-sectional study

Introduction: The extent of preventable medication-related hospital admissions and medication-related issues in primary care is significant enough to justify developing decision support systems for medication safety surveillance. The prerequisite for such systems is defining a relevant set of medication safety-related indicators and understanding the influence of both patient and general practice characteristics on medication prescribing and monitoring. Objective: The aim of the study was to investigate the feasibility of linked primary and secondary care electronic health record data for surveillance of medication safety, examining not only prescribing but also monitoring, and associations with patient- and general practice-level characteristics. Methods: A cross-sectional study was conducted using linked records of patients served by one hospital and over 50 general practices in Salford, UK. Statistical analysis consisted of mixed-effects logistic models, relating prescribing safety indicators to potential determinants. Results: The overall prevalence (proportion of patients with at least one medication safety hazard) was 5.45 % for prescribing indicators and 7.65 % for monitoring indicators. Older patients and those on multiple medications were at higher risk of prescribing hazards, but at lower risk of missed monitoring. The odds of missed monitoring among all patients were 25 % less for males, 50 % less for patients in practices that provide general practitioner training, and threefold higher in practices serving the most deprived compared with the least deprived areas. Practices with more prescribing hazards did not tend to show more monitoring issues. Conclusions:Systematic collection, collation, and analysis of linked primary and secondary care records produce plausible and useful information about medication safety for a health system. Medication safety surveillance systems should pay close attention to patient age and polypharmacy with respect to both prescribing and monitoring failures; treat prescribing and monitoring as different statistical processes, rather than a combined measure of prescribing safety; and audit the socio-economic equity of missed monitoring

Оценка информативности получаемого материала при прицельной биопсии и эндоскопическом удалении колоректальных полипов

This research is based on histological investigation of targeted biopsy material and resected polyps’ at 354 patients who applied to National Center of Oncology from 2005 to 2010. All patients underwent targeted biopsy at first with subsequent endoscopic polypectomy and 494 polyps were removed and histologically investigated. The most prevalence type was tubular polyp — 212 (43 %) cases. The rest types of polyps were distributed as follow: tubule-villous type — 125 (25.3 %), villous type — 16 (3.2 %), inflammatory type — 28 (5.7 %), hyperplastic type — 40 (8.1 %), hamartoma type — 21 (4.3 %) cases. In 52 (10.4 %) cases malignant polyps were revealed.Sensitivity of targeted biopsy in iagnostics of dysplasia was 65.1 % while in revealing of malignancy was even lower — just 36.5 %. So we consider performing of endoscopic polypectomy and histological evaluation of resected polyps in all case even after previous targeted biopsy.Данное исследование основано на результатах сравнительного гистологического изучения биопсийного материала и удаленных колоректальных полипов у 354 пациентов в отделении эндоскопии Национального центра онкологии в период с 2005 по 2010 г. Всем больным была выполнена предварительная прицельная биопсия из колоректальных полипов и последующая эндоскопическая полипэктомия (удалено 494 полипа). Наиболее распространенным гистологическим типом оказался тубулярный полип — 212 (43 %) случая. Остальные типы полипов распределялись следующим образом: тубуло-виллезный тип — 125 (25,3 %) случаев, виллезный тип — 16 (3,2 %), воспалительный тип — 28 (5,7 %), гиперпластический тип — 40 (8,1 %) и гамартомный тип полипа — 21 (4,3 %) случай. В 52 (10,4 %) случаях были выявлены малигнизированные полипы. Чувствительность прицельной биопсии в определении дисплазии составила 65,1 %, а в выявлении малигнизации — лишь 36,5 %. Таким образом, мы считаем необходимым гистологическое исследование удаленных полипов после эндоскопической полипэктомии во всех случаях, даже при наличии результатов предварительной прицельной биопсии

Experience in International Cooperation on Organization of Anti-Epidemic Measures by Health Care Institutions under COVID-19 Pandemic in the Republic of Uzbekistan

The results of the joint work of a panel of experts from Rospotrebnadzor and healthcare professionals of the Republic of Uzbekistan on organizing activities to counter the spread of the SARS-CoV-2 virus are described in the paper.The goal of the study was to determine the main driving forces of COVID-19 spread in the Republic of Uzbekistan and develop an action plan to reduce the incidence of coronavirus infection caused by the SARS-CoV-2 virus.Materials and methods. The organization of work in 14 health care institutions in Tashkent and Samarkand, as well as in Tashkent and Samarkand Regions, was analyzed: in 7 laboratories, 6 hospitals and 1 polyclinic. The routes for the movement of personnel, the demarcation of green and red zones, the features of disinfection and the use of personal protective equipment were studied. Attention is drawn to the diagnosis of COVID-19, the use of therapy aimed at reducing the period of virus shedding, the criteria for lifting quarantine restrictions for patients.Results and discussion. The main factors in the organization of work of institutions that contribute to the spread of COVID-19 among medical personnel and the population have been identifed: the lack of equipped gateways between the red and green zones with the accessibility of adequate disinfection, the wrong choice of personal protective equipment, monitoring of contact persons for 10 days, discharge from hospitals based on clinical improvement. The incorrect use of antiviral therapy, the lack of differentiated approaches to the selection of optimal regimens have been noted. Proposals are formulated for organizing the work of healthcare institutions, taking into account the requirements of biological safety. The introduction of targeted measures in addition to those previously adopted has led to a signifcant improvement in the epidemic situation: the total number of active cases in the Republic of Uzbekistan, despite the increase in testing volumes, decreased from 3,686 people on August 23 to 2335 on October 27. Towards December 20, 2020, 97 % of patients recovered completely. All diagnostic triage centers in the Republic of Uzbekistan are closed due to the absence of patients with COVID-19, most of the country’s medical institutions previously re-profled for patients with coronavirus infection have returned to the routine operations

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

Correction: Volume53, Issue5 Page 762-762 DOI: 10.1038/s41588-021-00832-z Published MAY 2021Genetic studies of blood pressure (BP) to date have mainly analyzed common variants (minor allele frequency > 0.05). In a meta-analysis of up to similar to 1.3 million participants, we discovered 106 new BP-associated genomic regions and 87 rare (minor allele frequencyPeer reviewe