11 research outputs found

    Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

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    Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives. Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an updated classification of cell death subroutines focusing on mechanistic and essential (as opposed to correlative and dispensable) aspects of the process. As we provide molecularly oriented definitions of terms including intrinsic apoptosis, extrinsic apoptosis, mitochondrial permeability transition (MPT)-driven necrosis, necroptosis, ferroptosis, pyroptosis, parthanatos, entotic cell death, NETotic cell death, lysosome-dependent cell death, autophagy-dependent cell death, immunogenic cell death, cellular senescence, and mitotic catastrophe, we discuss the utility of neologisms that refer to highly specialized instances of these processes. The mission of the NCCD is to provide a widely accepted nomenclature on cell death in support of the continued development of the field

    Time's Up: Analysing the Feminist Potential of Time Banks

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    Time banks are an alternative economic system proposed to address social problems by stimulating work and exchange through time‐based currency. They aim to redefine work and money, through building social capital to alleviate social problems. As women are disproportionately affected by these problems, it follows that membership is predominantly female, often poor. This article takes the position that time banks provide a lens through which to theorise the feminist potential of alternative forms of economic organisation. It examines the ways in which feminists, and time banks, have sought to redefine the concepts of work and money, as well as the context of time banks within the Third Sector. ‘The reality’ of these concepts in practice is then critically analysed using empirical data from a year as an active participant within a time bank. The findings demonstrate the complex issues regarding how the time bank functioned in practice, particularly in relation to how members engaged with it, and articulated their participation. Further, the way in which the system co‐opted feminist potentials of alternative economic practices as part of the Third Sector, through a conception of social capital, is shown to be problematic in terms of exploiting the energies of already exploited women. This research shows the need for ongoing critical examination of initiatives targetted at social problems, particularly those mirroring feminist activism, in order to prevent the co‐option of energies and work

    Comparative Anatomy of the Bony Labyrinth (Inner Ear) of Placental Mammals

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    Strahlenbedingte Knochenschäden

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    The Ontogeny-Phylogeny Nexus in a Nutshell: Implications for Primatology and Paleoanthropology

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    3 The Ontogeny–Phylogeny Nexus in a Nutshell: Implications for Primatology and Paleoanthropology

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