The influence of remote aerosol forcing from industrialised economies on the future evolution of East and West African rainfall

Past changes in global industrial aerosol emissions have played a significant role in historical shifts in African rainfall and yet assessment of the impact on African rainfall of near term (10-40 year) potential aerosol emission pathways remains largely unexplored. Whilst existing literature links future aerosol declines to a northward shift of Sahel rainfall, existing climate projections rely on RCP scenarios that do not explore the range of air quality drivers. Here we present projections from two emission scenarios that better envelope the range of potential aerosol emissions. More aggressive emission cuts results in northward shifts of the tropical rain-bands whose signal can emerge from expected internal variability on short, 10-20 year, time horizons. We also show for the first time that this northward shift also impacts East Africa, with evidence of delays to both onset and withdrawal of the Short Rains. However, comparisons of rainfall impacts across models suggest that only certain aspects of both the West and East African model responses may be robust, given model uncertainties. This work motivates the need for wider exploration of air quality scenarios in the climate science community to assess the robustness of these projected changes and to provide evidence to underpin climate adaptation in Africa. In particular, revised estimates of emission impacts of legislated measures every 5-10 years would have a value in providing near term climate adaptation information for African stakeholders

First records of the family Scoloplacidae (Siluriformes, Loricarioidei) in Colombia, including a range expansion of Scoloplax baileyi Rocha, Lazzarotto & Py-Daniel, 2012

The Neotropical family Scoloplacidae is a monogeneric group of miniature freshwater catfishes that includes 6 species. Scoloplax dicra has the widest distribution across the Amazon basin, except in the western upper portions. We collected 3 specimens from localities close to Leticia in Colombia, corresponding to S. baileyi and S. dicra, constituting the westernmost records of the family for the Amazon basin and the first for Colombia

Fisiología de la nutrición y del estrés en las primeras fases de vida del pulpo común (Octopus vulgaris). Resultados del proyecto OCTOPHYS

El cultivo del pulpo común (Oclopus vulgaris) está severamente limitado por las altas mortalidades que se producen durante su cultivo larvano, aunque en la actualidad, las causas especfficas de tan alta mortalidad siguen siendo desconocidas. Este proyecto pretende adquirir conocimientos básicos sobre la biología y fisiologia de las paralarvas a través de un enfoque multidisciplinarque incluye aspectos innovadores relacionados con la fisiologia de la nutrición y el estrés. Los objetivos propuestos están basados en un fuerte input zootécnico y prevén el uso de herramientas biométricas, bioquímicas, enzimáticas, moleculares y proteómicas, con el fin último de optimizar la condición y supervivencia de las paralarvas. Incluyen asimismo la búsqueda y selección de biomarcadores capaces de detectar y cuantíñcar el estrés nutricional.The culture oflhe common octopus (Octopus vulgaris) is hindered by high mortalities encountered during its paralarval rearing, allhough at present, Ihe specific causes forlhe high mortalities observed remain unidentified. This project aims at galhering a beller understanding of Ihe basic biology and physiology ofthe paralarvae, through a multidisciplinary and integrated approach, which includes Ihe study oflhe physiology 01 nutrition and!he evaluation 01Ihe stress condition. The objectives proposed are basad on a strong zootechnical input and foresee Ihe use of biometric, biochemical, enzymatic, molecular biology and proteomic tools, pointing towards the ultimate optimisation of Ihe paralarval condition and survival. They also include Ihe study ofthe nutritionally-derived stress and Ihe selection ofbiomarkers capable of its detection and quantification

Measurement of the Lifetime Difference Between B_s Mass Eigenstates

We present measurements of the lifetimes and polarization amplitudes for B_s --> J/psi phi and B_d --> J/psi K*0 decays. Lifetimes of the heavy (H) and light (L) mass eigenstates in the B_s system are separately measured for the first time by determining the relative contributions of amplitudes with definite CP as a function of the decay time. Using 203 +/- 15 B_s decays, we obtain tau_L = (1.05 +{0.16}/-{0.13} +/- 0.02) ps and tau_H = (2.07 +{0.58}/-{0.46} +/- 0.03) ps. Expressed in terms of the difference DeltaGamma_s and average Gamma_s, of the decay rates of the two eigenstates, the results are DeltaGamma_s/Gamma_s = (65 +{25}/-{33} +/- 1)%, and DeltaGamma_s = (0.47 +{0.19}/-{0.24} +/- 0.01) inverse ps.Comment: 8 pages, 3 figures, 2 tables; as published in Physical Review Letters on 16 March 2005; revisions are for length and typesetting only, no changes in results or conclusion

Fisiología de la nutrición y del estrés en las primeras fases de vida del pulpo común (Octopus vulgaris). Resultados del proyecto OCTOPHYS

El cultivo del pulpo común (Oclopus vulgaris) está severamente limitado por las altas mortalidades que se producen durante su cultivo larvano, aunque en la actualidad, las causas especfficas de tan alta mortalidad siguen siendo desconocidas. Este proyecto pretende adquirir conocimientos básicos sobre la biología y fisiologia de las paralarvas a través de un enfoque multidisciplinarque incluye aspectos innovadores relacionados con la fisiologia de la nutrición y el estrés. Los objetivos propuestos están basados en un fuerte input zootécnico y prevén el uso de herramientas biométricas, bioquímicas, enzimáticas, moleculares y proteómicas, con el fin último de optimizar la condición y supervivencia de las paralarvas. Incluyen asimismo la búsqueda y selección de biomarcadores capaces de detectar y cuantíñcar el estrés nutricional.The culture oflhe common octopus (Octopus vulgaris) is hindered by high mortalities encountered during its paralarval rearing, allhough at present, Ihe specific causes forlhe high mortalities observed remain unidentified. This project aims at galhering a beller understanding of Ihe basic biology and physiology ofthe paralarvae, through a multidisciplinary and integrated approach, which includes Ihe study oflhe physiology 01 nutrition and!he evaluation 01Ihe stress condition. The objectives proposed are basad on a strong zootechnical input and foresee Ihe use of biometric, biochemical, enzymatic, molecular biology and proteomic tools, pointing towards the ultimate optimisation of Ihe paralarval condition and survival. They also include Ihe study ofthe nutritionally-derived stress and Ihe selection ofbiomarkers capable of its detection and quantification

Predicting September Arctic Sea Ice: A Multi-Model Seasonal Skill Comparison

Abstract This study quantifies the state-of-the-art in the rapidly growing field of seasonal Arctic sea ice prediction. A novel multi-model dataset of retrospective seasonal predictions of September Arctic sea ice is created and analyzed, consisting of community contributions from 17 statistical models and 17 dynamical models. Prediction skill is compared over the period 2001–2020 for predictions of Pan-Arctic sea ice extent (SIE), regional SIE, and local sea ice concentration (SIC) initialized on June 1, July 1, August 1, and September 1. This diverse set of statistical and dynamical models can individually predict linearly detrended Pan-Arctic SIE anomalies with skill, and a multi-model median prediction has correlation coefficients of 0.79, 0.86, 0.92, and 0.99 at these respective initialization times. Regional SIE predictions have similar skill to Pan-Arctic predictions in the Alaskan and Siberian regions, whereas regional skill is lower in the Canadian, Atlantic, and Central Arctic sectors. The skill of dynamical and statistical models is generally comparable for Pan-Arctic SIE, whereas dynamical models outperform their statistical counterparts for regional and local predictions. The prediction systems are found to provide the most value added relative to basic reference forecasts in the extreme SIE years of 1996, 2007, and 2012. SIE prediction errors do not show clear trends over time, suggesting that there has been minimal change in inherent sea ice predictability over the satellite era. Overall, this study demonstrates that there are bright prospects for skillful operational predictions of September sea ice at least three months in advance.</jats:p

Venezuela's humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region.

In the past 5-10 years, Venezuela has faced a severe economic crisis, precipitated by political instability and declining oil revenue. Public health provision has been affected particularly. In this Review, we assess the impact of Venezuela's health-care crisis on vector-borne diseases, and the spillover into neighbouring countries. Between 2000 and 2015, Venezuela witnessed a 359% increase in malaria cases, followed by a 71% increase in 2017 (411 586 cases) compared with 2016 (240 613). Neighbouring countries, such as Brazil, have reported an escalating trend of imported malaria cases from Venezuela, from 1538 in 2014 to 3129 in 2017. In Venezuela, active Chagas disease transmission has been reported, with seroprevalence in children (<10 years), estimated to be as high as 12·5% in one community tested (n=64). Dengue incidence increased by more than four times between 1990 and 2016. The estimated incidence of chikungunya during its epidemic peak is 6975 cases per 100 000 people and that of Zika virus is 2057 cases per 100 000 people. The re-emergence of many vector-borne diseases represents a public health crisis in Venezuela and has the possibility of severely undermining regional disease elimination efforts. National, regional, and global authorities must take action to address these worsening epidemics and prevent their expansion beyond Venezuelan borders

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

Caracterización del Banco de La Concepción

Se integra información hidrográfica, geomorfológica, sedimentológica, biológica, sobre hábitats marinos y pesquera, para establecer las bases ecológicas necesarias para la protección y conservación del Banco de La ConcepciónEl proyecto INDEMARES ha permitido utilizar amplios medios económicos y personales para estudiar en detalle y desde múltiples perspectivas la zona del Banco de La Concepción. Se han aplicado metodologías para el estudio de la hidrografía, caracterizando la región, describiendo sus principales masas de agua y la hidrodinámica de las corrientes. También se ha abordado la geología de la zona, incluyendo levantamientos batimétricos, perfiles sísmicos, muestreos de sedimento y petrológicos, obteniendo modelos digitales del terreno, mapas de tipos de fondo, geomorfológicos. Se han caracterizado las comunidades bentopelágicas, demersales, epibentónicas y endobentónicas, prestando especial atención a aquellas que conforman o estructuran los hábitats sensibles cuyo inventariado y cartografía era objeto principal del proyecto. Los trabajos de identificación de hábitats se han realizado con muestreadores directos, pero también con muestreadores visuales, que han permitido hacer un mayor esfuerzo de muestreo sin aumentar el impacto sobre los fondos de la zona. Por otro lado se ha estudiado la huella pesquera de la zona por medio del análisis de los datos VMS y los cuadernos de pesca proporcionados por la SGP, además de una ardua labor a pie de puerto de entrevistas y encuestas. Toda la información ha sido gestionada y analizada por diferentes grupos de investigación de diferentes centros (Universidad de La Laguna, Instituto Universitario de Ciencias Políticas y Sociales, Universidad de Las Palmas de Gran Canaria, Instituto de Ciencias del Mar de Barcelona, Universidad de Barcelona, Centro de Investigaciones Medioambientales del Atlántico, Centro Oceanográfico de Santander y Centro Oceanográfico de Málaga del Instituto Español de Oceanografía, …), aunque el grueso de esta labor, además de la coordinación, se ha llevado a cabo en el Centro Oceanográfico de Canarias del Instituto Español de Oceanografía. Los resultados permiten tener un conocimiento profundo y multidisciplinar de la zona de estudio comparable a pocos proyectos de investigación marina en la macaronesia. El estudio oceanográfico, el geológico, y el de las comunidades biológicas, ha permitido la caracterización de los hábitats de la zona, y su cartografiado mediante el intenso muestreo y la aplicación de análisis de idoneidad de hábitats.INDEMARES Project made possible to bring together economic and staff resources to study in detail, and from multiple perspectives, the area of Banco de La Concepción. Methodologies have been applied to study hydrography, making a regional characterization, depicting main water masses, and current hydrodynamics. Geology has been tackled including bathymetric uplifting, seismic profiles, sediment and petrological sampling, obtaining digital terrain models, type of bottom maps, geomorphological maps, as an output. Benthopelagic, demersal, epibenthic and endobenthic communities have been characterized, paying special attention to sensitive habitats which inventory and mapping was the project’s main aim. Habitat identification has been made with direct and visual samplers, the latter making a major sampling effort possible without an increase of bottom impact. Moreover, fisheries footprint has been identified by Vessel Monitoring System data, together with logbooks from Secretaría General de Pesca (Fisheries Ministry), as well as a hard interviewing and surveying task at landing points. Information has been managed and analysed by different research groups from different Centres (Universidad de La Laguna, Instituto Universitario de Ciencias Políticas y Sociales, Universidad de Las Palmas de Gran Canaria, Instituto de Ciencias del Mar de Barcelona, Universidad de Barcelona, Centro de Investigaciones Medioambientales del Atlántico, Centro Oceanográfico de Santander y Centro Oceanográfico de Málaga del Instituto Español de Oceanografía), although the main body of the work, plus coordination, has been made by the Canary Islands Oceanographic Centre, from the Spanish Institute of Oceanography. Results let us have a multidisciplinary profound knowledge of the study zone, comparable to few other marine research projects off Macaronesia. The study about oceanography, geology and biologic communities has allowed the habitats characterization and mapping by means of intensive sampling and habitat suitability analysis.Instituto Español de Oceanografía, Comisión Europea Programa LIFE+, Fundación Biodiversida