37 research outputs found

    Fungal enrichment of cassava peels proteins

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    About 60% of the cassava produced all over the world is used for human consumption. These peels waste were found to contain 42.6% carbohydrate, 1.6% protein, 12.1% ether extract, 5.0% total ash and 22.5% crude fibre. With the advent of biotechnology approaches, there are opportunities for economic utilization of agro industrial residues such as cassava peels waste. The Microorganisms isolated from the fermenting cassava waste were Aspergillus niger, A. flavus, and A. fumigatus. These and Trichoderma sp. from soil were studied for their ability to increase the protein content of cassava peels waste.Keywords: Cassava peels, Aspergillus flavus, Aspergillus niger, Aspergillus fumigatu

    Activity-Based Funding of Hospitals and Its Impact on Mortality, Readmission, Discharge Destination, Severity of Illness, and Volume of Care: A Systematic Review and Meta-Analysis

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    Background: Activity-based funding (ABF) of hospitals is a policy intervention intended to re-shape incentives across health systems through the use of diagnosis-related groups. Many countries are adopting or actively promoting ABF. We assessed the effect of ABF on key measures potentially affecting patients and health care systems: mortality (acute and post-acute care); readmission rates; discharge rate to post-acute care following hospitalization; severity of illness; volume of care.     Methods: We undertook a systematic review and meta-analysis of the worldwide evidence produced since 1980. We included all studies reporting original quantitative data comparing the impact of ABF versus alternative funding systems in acute care settings, regardless of language. We searched 9 electronic databases (OVID MEDLINE, EMBASE, OVID Healthstar, CINAHL, Cochrane CENTRAL, Health Technology Assessment, NHS Economic Evaluation Database, Cochrane Database of Systematic Reviews, and Business Source), hand-searched reference lists, and consulted with experts. Paired reviewers independently screened for eligibility, abstracted data, and assessed study credibility according to a pre-defined scoring system, resolving conflicts by discussion or adjudication.     Results: Of 16,565 unique citations, 50 US studies and 15 studies from 9 other countries proved eligible (i.e. Australia, Austria, England, Germany, Israel, Italy, Scotland, Sweden, Switzerland). We found consistent and robust differences between ABF and no-ABF in discharge to post-acute care, showing a 24% increase with ABF (pooled relative risk = 1.24, 95% CI 1.18–1.31). Results also suggested a possible increase in readmission with ABF, and an apparent increase in severity of illness, perhaps reflecting differences in diagnostic coding. Although we found no consistent, systematic differences in mortality rates and volume of care, results varied widely across studies, some suggesting appreciable benefits from ABF, and others suggesting deleterious consequences.     Conclusions: Transitioning to ABF is associated with important policy- and clinically-relevant changes. Evidence suggests substantial increases in admissions to post-acute care following hospitalization, with implications for system capacity and equitable access to care. High variability in results of other outcomes leaves the impact in particular settings uncertain, and may not allow a jurisdiction to predict if ABF would be harmless. Decision-makers considering ABF should plan for likely increases in post-acute care admissions, and be aware of the large uncertainty around impacts on other critical outcomes

    Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy

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    Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe

    Global variation in anastomosis and end colostomy formation following left-sided colorectal resection

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    Background End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection. Methods This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associated with colostomy formation versus primary anastomosis were explored using a multilevel, multivariable logistic regression model. Results In total, 1635 patients from 242 hospitals in 57 countries undergoing left-sided colorectal resection were included: 113 (6·9 per cent) from low-HDI, 254 (15·5 per cent) from middle-HDI and 1268 (77·6 per cent) from high-HDI countries. There was a higher proportion of patients with perforated disease (57·5, 40·9 and 35·4 per cent; P < 0·001) and subsequent use of end colostomy (52·2, 24·8 and 18·9 per cent; P < 0·001) in low- compared with middle- and high-HDI settings. The association with colostomy use in low-HDI settings persisted (odds ratio (OR) 3·20, 95 per cent c.i. 1·35 to 7·57; P = 0·008) after risk adjustment for malignant disease (OR 2·34, 1·65 to 3·32; P < 0·001), emergency surgery (OR 4·08, 2·73 to 6·10; P < 0·001), time to operation at least 48 h (OR 1·99, 1·28 to 3·09; P = 0·002) and disease perforation (OR 4·00, 2·81 to 5·69; P < 0·001). Conclusion Global differences existed in the proportion of patients receiving end stomas after left-sided colorectal resection based on income, which went beyond case mix alone

    Short communication: The salvage value of bovine foetuses in slaughtered cattle within Ogun state, Nigeria

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    Bovine foetuses recovered from abattoirs and slaughter slabs in Ogun State were previously discarded.  Recently, a total of 327 skins of foetuses in the third trimester were tanned to produce leathers for the manufacture of 439 pairs of shoes which yielded a revenue of N33,124 for the State Goverment. The skim of foetuses in both the first and second trimesters were used in the manufacture of local drums. Foetal carcases were processed as pet foods by dog and cat owners. Some foetal tissues could be preserved for use in the laboratories for research purposes. Such utilization of foetues has reduced losses which they brought about when there was no need for them.Key words: Bovine foetus, salvage valu

    Assessment of abattoir and slaughter slab operations in Oyo State, Nigeria

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    Yield of ungatched incubator eggs and its replacement value in soyabean meal diets fed to cockerels

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    Blood chemistry and carcass yield of cockerels fed melon husk diets

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    Reproductive Performance Of West African Dwarf Sheep And Goats At Village Level In Ogun State, Nigeria

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    Reproductive performance or 20 pregnant ewes and 20 pregnant does of West African Dwarf breed at village level in Ogun State, Nigeria were compared in a study which lasted for 8 months. Litter size in ewes was1.50 while that of does was 1.85. The number of males produced by the two species out-numbered that of females. However, multiple births were higher in goat than in sheep. Results or birth weights and body weights of lambs and kids at 3 month of age were significantly different (P &lt; 0.05). Lambs were heavier at birth with overall mean birth weight of 2.00kg compared with 1.48kg recorded for kids. At the age of 3 months, the overall body weight of lamb was 1038kg while that of kid was 7.61kg. Mortality in lamb was 23.33% as against 10.81 % in kids. Effective management system of West African Dwarf sheep and goats at village level before andafter birth will improve the reproductive efficiency of the two species.Keywords: Reproductive performance, WAD sheep and goat

    Hatchability of chicken eggs as influenced by turning frequency in hurricane lantern incubator

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    An experiment was conducted to determine the influence of turning frequency of chicken eggs on hatchability in hurricane lantern incubator. There were four treatments in which eggs were not turned intreatment one (control), those in treatment two were turned once daily (morning), treatment three turned twice daily (morning and afternoon) while treatment four were turned thrice daily (morning, afternoonand evening). A range of 9.86 - 11.51% egg weight loss was obtained with the lowest value of 9.86% recorded in the control experiment. Egg turning three times daily produced highest hatchability of 72.90%. Embryonic mortality occurred in all the treatments. Early embryonic mortality (DIG) was highest (70.85%) in treatment two while late embryonic mortality (DIS) was highest (66.65%) in treatment three.Hatching occurred in the three zones of the egg. Most of the chicks hatched from the equatorial region while few ones hatched from the narrow end of the egg. Manual turning of eggs three times a day isrecommended for hurricane lantern incubator in order to enhance minimal egg weight loss and higher hatchability of chicks. Such incubator could be used for hatching eggs of domestic fowls, turkeys,ducks, etc thereby taking hatchery operations to the door- steps of small-scale poultry farmers
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