Non-Scissors-Mode Behaviour of Isovector Magnetic Dipole Orbital Transitions Involving Isospin Transfer

We study the response of isovector orbital magnetic dipole (IOMD) transitions to the quadrupole-quadrupole ($Q \cdot Q$) interaction, to the isospin-conserving pairing interaction (ICP) and to combinations of both. We find qualitatively different behaviours for transitions in which the final isospin differs from the initial isospin versus cases where the two isospins are the same. For $N=Z$ even-even nuclei with $J^{\pi}=0^+, T=0$ ground states such as $^8Be$ and $^{20}Ne$, the summed $T=0 \to T=1$ IOMD from the ground state to all the $J=1, T=1$ states in the $0 \hbar \omega$ space does not vanish when the $Q \cdot Q$ interaction is turned off. The pairing interaction (ICP) alone leads to a finite transition rate. For nuclei with $J=0^+, T=1$ ground states such as $^{10}Be$ and $^{22}Ne$, the summed $T=1 \to T=1$ IOMD $does$ vanish when the $Q \cdot Q$ interaction is turned off, as is expected in a good scissors-mode behaviour. However this is not the case for the corresponding sum of the $T=1 \to T=2$ IOMD transitions. In $^{22}Ne$ (but not in $^{10}Be$) the sum of the $T=1 \to T=2$ IOMD transitions is remarkably insensitive to the strengths of both the $Q \cdot Q$ and the ICP interactions. In $^{22}Ne$ an energy weighted-sum is similarly insensitive. All our calculations were carried out in the $0 \hbar \omega$ space.Comment: 19 pages (including 5 figures). submitted to Nucl. Phys.

Formar para incluir: Referencial de reabilitação profissional Appacdm-Évora.

O programa Referencial de Reabilitação Profissional (RRP-APPACDM) tem as suas raízes no Programa Holístico de Reabilitação Neuropsicológica, que teve inicio no Centro de Reabilitação Profissional de Gaia (CRPG) (Guerreiro, Almeida, Fabela, Dores, & Castro-Caldas, 2009; Almeida et al., 2015). O modelo de Ben Yashai (Ben Yashai & Daniels-Zide, 2000) é o referencial seguido pelo RRP-APPACDM e CRPG, tendo estabelecido como principais objetivos: a) a promoção do funcionamento físico e psicológico empoderando a autonomia; b) melhorar o ajustamento psicossocial, através do desenvolvimento de competências interpessoais e aceitação da nova condição; e c) apoiar a criação de projetos de integração práticos. Especialmente, no que diz respeito ao RRP-APPACDM, os objetivos são: 1) Readaptação pessoal e social através da recuperação, atualização e otimização de competências pessoais; 2) desenvolvimento de autoconsciência, de potencial e áreas de crescimento, aceitando simultaneamente as limitações; 3) promoção de aceitação de objetivos realistas e exequíveis; 4) empoderar o desenvolvimento de estratégias de coping, resolução de problemas e flexibilização cognitivo-comportamental; 5) apoiar o desenvolvimento e melhoria nas relações interpessoais e fortalecimento de redes de suporte social; 6) encorajar as experiências vocacionais que facilitem a reorganização dos valores vocacionais enquanto (re)constroem perceções ajustadas sobre a formação vocacional e mercado de trabalho; 7) requalificação e/ou reabilitação vocacional procurando uma formação vocacional ajustada; 8) requalificação e/ou reabilitação vocacional com o objetivo de promover medidas de apoio à integração profissional recorrendo às competências e conhecimentos adquiridas antes da lesão, beneficiando de apoio técnico especializado para integração socio-vocacional, apoio para tarefas e papéis necessários para um cargo laboral e mediação de comportamentos pessoas e sociais adequados ao estatuto laboral. A nível de competências transversais abordadas, o programa da APPACDM trabalha competências tais como: flexibilidade, resolução de problemas, autodiretividade, autorregulação e criatividade. Estes transversal skills são trabalhados nos módulos: Comunicação e Relacionamentos Interpessoais; Atividades de Vida Diária; nas Terapias individuais (e.g., Psicologia, Fisioterapia, Terapia ocupacional, terapia da fala, reabilitação funcional em grupo, treino cognitivo).FCT e três projetos ENABLIN+ (Leonardo Da Vinci), Cognition & Inclusion (ERASMUS+) e LLL-HUB (Lifelong Learning Programm) e da I Conferência Europeia em Life Long Learning (realizada na Universidade de Évora com os apoios do Departamento de Psicologia e da Escola de Ciências Sociais), e da Associação Portuguesa de Gestão de Pessoas (APG) e a Associação Nacional para a Qualificação e Ensino Profissiona

Ground state particle-particle correlations and double beta decay

A self-consistent formalism for the double beta decay of Fermi type is provided. The particle-particle channel of the two-body interaction is considered first in the mean field equations and then in the QRPA. The resulting approach is called the QRPA with a self-consistent mean field (QRPASMF). The mode provided by QRPASMF, does not collapse for any strength of the particle-particle interaction. The transition amplitude for double beta decay is almost insensitive to the variation of the particle-particle interaction. Comparing it with the result of the standard pnQRPA, it is smaller by a factor 6. The prediction for transition amplitude agrees quite well with the exact result. The present approach is the only one which produces a strong decrease of the amplitude and at the same time does not alter the stability of the ground state.Comment: 23 pages, 7 figure

Detection Of Metabolic Syndrome Features Among Childhood Cancer Survivors: A Target To Prevent Disease

Along with the growing epidemic of obesity, the risk of atherosclerosis, cardiovascular disease morbidity, and mortality are increasing markedly. Several risk factors for cardiovascular disease, such as visceral obesity, glucose intolerance, arterial hypertension, and dyslipidemia commonly cluster together as a condition currently known as metabolic syndrome. Thus far, insulin resistance, and endothelial dysfunction are the primary events of the metabolic syndrome. Several groups have recommended clinical criteria for the diagnosis of metabolic syndrome in adults. Nonetheless, in what concerns children and adolescents, there are no unified definitions, and modified adult criteria have been suggested by many authors, despite major problems. Some pediatric disease states are at risk for premature cardiovascular disease, with clinical coronary events occurring very early in adult life. Survivors of specific pediatric cancer groups, particularly acute lymphocytic leukemia, central nervous system tumors, sarcomas, lymphomas, testicular cancer, and following bone marrow transplantation, may develop metabolic syndrome traits due to: hormonal deficiencies (growth hormone deficiency, thyroid dysfunction, and gonadal failure), drug or radiotherapy damage, endothelial impairment, physical inactivity, adipose tissue dysfunction, and/or drug-induced magnesium deficiency. 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Comparison Of Bone Quantity By Ultrasound Measurements Of Phalanges Between White And Black Children Living In Paraná,brazil, With Europeans

The objective of this study was to determine bone quantity by ultrasound measurements of the proximal fnger phalanges (AD-SoS = amplitude-dependent speed of sound) of healthy Brazilian schoolchildren living in Paraná, Brazil, and to compare these values with European populations. The sample was composed of 1356 Brazilian schoolchildren of both genders (660 males, 696 females), aged 6 to 11 years, divided into white (840) and black (516) groups and compared to age- and gender-matched Europeans. AD-SoS of the schoolchildren increased significantly with age for both genders. Significantly higher AD-SoS values were observed for the white children (1916 ± 58) compared to their black counterparts (1898 ± 72) and for the female gender (1920 ± 61) compared to the male gender (1898 ± 66). Overall, the AD-SoS outcomes for females were similar to those of European studies. However, the AD-SoS of the Brazilian schoolchildren of both genders and skin colors was lower than that reported for children in Poland. AD-SoS outcomes for Brazilian schoolboys were similar to those obtained in Italian studies and were lower than those of the Spanish children. In conclusion, Brazilian schoolchildren of both genders and skin colors showed lower bone quantities than Polish children and Spanish males, and levels similar to Italian children and Spanish females.4310976981Mora, S., Gilsanz, V., Establishment of peak bone mass (2003) En-docrinol Metab Clin North Am, 32, pp. 39-63Silva, C.C., Goldberg, T.B., Teixeira, A.S., Dalmas, J.C., Bone mineralization among male adolescents: Critical years for bone mass gain (2004) J Pediatr, 80, pp. 461-467Habicht, J.P., Martorell, R., Yarbrough, C., Malina, R.M., Klein, R.E., Height and weight standards for preschool children. How relevant are ethnic differences in growth potential? 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Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs

The synthesis of an isosteric analog of the natural product and HDAC inhibitor largazole is described. The sulfur atom in the thizaole ring of the natural product has been replaced with an oxygen atom, constituting an oxazole ring. The biochemical activity and cytotoxicity of this species is described

The receptor AT1 appears to be important for the maintenance of bone mass and AT2 receptor function in periodontal bone loss appears to be regulated by AT1 receptor

A large number of experimental studies has demonstrated that angiotensin II (Ang II) is involved in key events of the inflammatory process. This study aimed to evaluate the role of Ang II type 1 (AT1) and Ang II type 2 (AT2) receptors on periodontitis. Methods: Experimental periodontitis was induced by placing a 5.0 nylon thread ligature around the second upper left molar of AT1 mice, no-ligature or ligature (AT1-NL and AT1-L), AT2 (AT2-NL or AT2-L) and wild type (WT-NL or L). Alveolar bone loss was scanned using Micro-CT. Cytokines, peptides and enzymes were analyzed from gingival tissues by Elisa and RT-PCR. Results: The blockade of AT1 receptor resulted in bone loss, even in healthy animals. Ang II receptor blockades did not prevent linear bone loss. Ang II and Ang 1-7 levels were significantly increased in the AT2-L (p < 0.01) group compared to AT2-NL and AT1-L. The genic expression of the Mas receptor was significantly increased in WT-L and AT2-L compared to (WT-NL and AT2-NL, respectively) and in AT1-L. Conclusions: Our data suggest that the receptor AT1 appears to be important for the maintenance of bone mass. AT2 receptor molecular function in periodontitis appears to be regulated by AT1

AT1 and AT2 receptor knockout changed osteonectin and bone density in mice in periodontal inflammation experimental model

BACKGROUND: The aim of this study was to evaluate the role of AT1 and AT2 receptors in a periodontal inflammation experimental model. METHODS: Periodontal inflammation was induced by LPS/Porphyromonas gingivalis. Maxillae, femur, and vertebra were scanned using Micro-CT. Maxillae were analyzed histopathologically, immunohistochemically, and by RT-PCR. RESULTS: The vertebra showed decreased BMD in AT1 H compared with WT H (p < 0.05). The femur showed increased Tb.Sp for AT1 H and AT2 H, p < 0.01 and p < 0.05, respectively. The Tb.N was decreased in the vertebra (WT H-AT1 H: p < 0.05; WT H-AT2 H: p < 0.05) and in the femur (WT H-AT1 H: p < 0.01; WT H-AT2 H: p < 0.05). AT1 PD increased linear bone loss (p < 0.05) and decreased osteoblast cells (p < 0.05). RANKL immunostaining was intense for AT1 PD and WT PD (p < 0.001). OPG was intense in the WT H, WT PD, and AT2 PD when compared to AT1 PD (p < 0.001). AT1 PD showed weak immunostaining for osteocalcin compared with WT H, WT PD, and AT2 PD (p < 0.001). AT1 H showed significantly stronger immunostaining for osteonectin in fibroblasts compared to AT2 H (p < 0.01). CONCLUSION: AT1 receptor knockout changed bone density, the quality and number of bone trabeculae, decreased the number of osteoblast cells, and increased osteonectin in fibroblasts

Measurement of the photon+b+b-jet production differential cross section in ppˉp\bar{p} collisions at \sqrt{s}=1.96~\TeV

We present measurements of the differential cross section dsigma/dpT_gamma for the inclusive production of a photon in association with a b-quark jet for photons with rapidities |y_gamma|< 1.0 and 30<pT_gamma <300 GeV, as well as for photons with 1.5<|y_gamma|< 2.5 and 30< pT_gamma <200 GeV, where pT_gamma is the photon transverse momentum. The b-quark jets are required to have pT>15 GeV and rapidity |y_jet| < 1.5. The results are based on data corresponding to an integrated luminosity of 8.7 fb^-1, recorded with the D0 detector at the Fermilab Tevatron $p\bar{p}$ Collider at sqrt(s)=1.96 TeV. The measured cross sections are compared with next-to-leading order perturbative QCD calculations using different sets of parton distribution functions as well as to predictions based on the kT-factorization QCD approach, and those from the Sherpa and Pythia Monte Carlo event generators.Comment: 10 pages, 9 figures, submitted to Phys. Lett.