404 research outputs found

    A Uniform Dress Code Policy for Middle/Junior High School

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    The purpose of this project was to design a model uniform dress code policy for the student population of a selected middle/junior high level school district in Washington State. To accomplish this purpose, a review of current literature regarding student dress codes and policies was conducted. Additionally, related information from selected public schools currently using student uniforms was obtained and analyzed

    Historical Climatology of the Alaska Climate Divisions

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    Complex topography and proximity to coasts results in multiple climate types in Alaska. Climate variability is regional in Alaska. Understanding regional climate variability can further evaluation of climate change, seasonal climate prediction, and teleconnection impacts. Novel climate divisions for Alaska present new avenues for climate products and services.NOAA Climate Program Office grant NA10OAR4310055 through CIFA

    Moderate versus light pressure massage therapy leads to greater weight gain in preterm infants

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    Sixty-eight preterm infants (M GA= 30 weeks) were randomly assigned to a moderate or to a light pressure massage therapy group to receive 15 massages three times per day for 5 days. Behavior state, stress behaviors and heart rate were recorded for 15 min before and during the first 15-min therapy session. Weight gain was recorded over the 5-day therapy period. The moderate versus light pressure massage group gained significantly more weight per day. During the behavior observations the moderate versus light pressure massage group showed significantly lower increases from the pre-session to the session recording on: (1) active sleep; (2) fussing; (3) crying; (4) movement; and (5) stress behavior (hiccupping). They also showed a smaller decrease in deep sleep, a greater decrease in heart rate and a greater increase in vagal tone. Thus, the moderate pressure massage therapy group appeared to be more relaxed and less aroused than the light pressure massage group which may have contributed to the greater weight gain of the moderate pressure massage therapy group.We would like to thank the mothers and infants who participated in this study and Julia Beutler, Larissa Feijo, Karla Gill and Yanexy Vera for their help with participant recruitment and data collection. We would also like to thank John Allen for his help with EKG analysis software. This research was supported by Senior Research Scientist Awards (#MH00331 and #AT01585) and an NIHM merit award (MH #46586) and a March of Dimes Grant (#12-FY03-48) to Tiffany Field, an NCCAM research Grant to Maria Hernandez-Reif (#AT00370) and an NCCAM research supplement (#AT00370-02S 1) to Miguel A. Diego and funding from Johnson and Johnson Pediatric Institute

    Deriving Historical Temperature and Precipitation Time Series For Alaska Climate Divisions Via Climatologically Aided Interpolation

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    This paper describes the construction of temperature and precipitation time series for climate divisions in Alaska for 1925-2015. Designed for NOAA climate monitoring applications, these new series build upon the divisional data of Bieniek et al. (2014) through the inclusion of additional observing stations, temperature bias adjustments, supplemental temperature elements, and enhanced computational techniques (i.e., climatologically aided interpolation). The new NOAA series are in general agreement with Bieniek et al. (2014), differences being attributable to the underlying methods used to compute divisional averages in each dataset. Trends in minimum temperature are significant in most divisions whereas trends in maximum temperature are generally not significant in the eastern third of the state. Likewise, the statewide rate of warming in minimum temperature (0.158°C dec-1) is roughly 50% larger than that of maximum temperature (0.101 °C dec-1). Trends in precipitation are not significant for most divisions or for the state as a whole

    Enhancement of CD8 T-cell function through modifying surface glycoproteins in young and old mice

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    Previous work from our laboratory has shown that modifying cell surface glycosylation with either a Clostridium perfringens -derived sialidase (CP-Siase), or an O-linked glycoprotein endopeptidase (OSGE) can enhance the function of CD4 T cells from both young and old mice at multiple levels. Here we have re-assessed the effect of age on CD8 T-cell function, and examined the outcome of enzymatic treatment with CP-Siase and OSGE on its different aspects. Pre-treatment of CD8 T cells with either CP-Siase or OSGE led to a significant increase in anti-CD3-mediated Ca 2+ response in both young and old mice. Pre-treated CD8 T cells from both age groups also displayed a significant increase in activation-induced CD69 and CD25 expression, and produced significantly higher amounts of interleukin-2 and interferon-Îł in comparison to their untreated counterparts. Furthermore, pretreatment with either enzyme enhanced granzyme B expression in CD8 T cells, and increased their cytolytic activity in vitro . These data support the notion that glycosylated surface proteins hinder CD8 T-cell activation and function in both young and old mice, and raise the possibility of significantly improving CD8 T cell function in older individuals through enzymatic alteration of surface glycoproteins.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75199/1/j.1365-2567.2006.02420.x.pd

    The state of the Martian climate

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    60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes

    Aging Impairs Recipient T Cell Intrinsic and Extrinsic Factors in Response to Transplantation

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    As increasing numbers of older people are listed for solid organ transplantation, there is an urgent need to better understand how aging modifies alloimmune responses. Here, we investigated whether aging impairs the ability of donor dendritic cells or recipient immunity to prime alloimmune responses to organ transplantation.Using murine experimental models, we found that aging impaired the host environment to expand and activate antigen specific CD8(+) T cells. Additionally, aging impaired the ability of polyclonal T cells to induce acute allograft rejection. However, the alloimmune priming capability of donor dendritic cells was preserved with aging.Aging impairs recipient responses, both T cell intrinsic and extrinsic, in response to organ transplantation
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