Imprint of Gravitational Lensing by Population III Stars in Gamma Ray Burst Light Curves

We propose a novel method to extract the imprint of gravitational lensing by Pop III stars in the light curves of Gamma Ray Bursts (GRBs). Significant portions of GRBs can originate in hypernovae of Pop III stars and be gravitationally lensed by foreground Pop III stars or their remnants. If the lens mass is on the order of $10^2-10^3M_\odot$ and the lens redshift is greater than 10, the time delay between two lensed images of a GRB is $\approx 1$s and the image separation is $\approx 10 \mu$as. Although it is difficult to resolve the two lensed images spatially with current facilities, the light curves of two images are superimposed with a delay of $\approx 1$ s. GRB light curves usually exhibit noticeable variability, where each spike is less than 1s. If a GRB is lensed, all spikes are superimposed with the same time delay. Hence, if the autocorrelation of light curve with changing time interval is calculated, it should show the resonance at the time delay of lensed images. Applying this autocorrelation method to GRB light curves which are archived as the {\it BATSE} catalogue, we demonstrate that more than half light curves can show the recognizable resonance, if they are lensed. Furthermore, in 1821 GRBs we actually find one candidate of GRB lensed by a Pop III star, which may be located at redshift 20-200. The present method is quite straightforward and therefore provides an effective tool to search for Pop III stars at redshift greater than 10. Using this method, we may find more candidates of GRBs lensed by Pop III stars in the data by the {\it Swift} satellite.Comment: 13 pages, 13 figures, accepted for publication in Ap

A Gyrochronology and Microvariability Survey of the Milky Way's Older Stars Using Kepler's Two-Wheels Program

Even with the diminished precision possible with only two reaction wheels, the Kepler spacecraft can obtain mmag level, time-resolved photometry of tens of thousands of sources. The presence of such a rich, large data set could be transformative for stellar astronomy. In this white paper, we discuss how rotation periods for a large ensemble of single and binary main- sequence dwarfs can yield a quantitative understanding of the evolution of stellar spin-down over time. This will allow us to calibrate rotation-based ages beyond ~1 Gyr, which is the oldest benchmark that exists today apart from the Sun. Measurement of rotation periods of M dwarfs past the fully-convective boundary will enable extension of gyrochronology to the end of the stellar main-sequence, yielding precise ages ({\sigma} ~10%) for the vast majority of nearby stars. It will also help set constraints on the angular momentum evolution and magnetic field generation in these stars. Our Kepler-based study would be supported by a suite of ongoing and future ground-based observations. Finally, we briefly discuss two ancillary science cases, detection of long-period low-mass eclipsing binaries and microvariability in white dwarfs and hot subdwarf B stars that the Kepler Two-Wheels Program would facilitate.Comment: Kepler white pape

Amnesia in Frontotemporal Dementia with Amyotrophic Lateral Sclerosis, Masquerading Alzheimer's Disease

A 68-year-old man with a clinical diagnosis of Alzheimer's disease (AD) later developed amyotrophic lateral sclerosis (ALS), which was confirmed at autopsy at age 72 years. Because neuronal loss and AD-type pathologies (Braak stage II for neurofibrillary tangles) were scant, TDP-43-positive intracytoplasmic inclusions in hippocampal dentate granular cells and in neurons in the subiculum and amygdala, even though small in amount, may represent the earliest lesions of ALS-related dementia and could be the cause of dementia in this patient. Although the persistent elevation of creatine kinase from the onset could be a pointer to the presence of motor involvement, more accurate characterization of dementia, which may differentiate ALS-related dementia and AD, is necessary

The Spitzer Survey of Stellar Structure in Galaxies (S^4G)

The Spitzer Survey of Stellar Structure in Galaxies S^4G is an Exploration Science Legacy Program approved for the Spitzer post-cryogenic mission. It is a volume-, magnitude-, and size-limited (d < 40 Mpc, |b| > 30 degrees, m_(Bcorr) < 15.5, D25>1') survey of 2,331 galaxies using IRAC at 3.6 and 4.5 microns. Each galaxy is observed for 240 s and mapped to > 1.5 x D25. The final mosaicked images have a typical 1 sigma rms noise level of 0.0072 and 0.0093 MJy / sr at 3.6 and 4.5 microns, respectively. Our azimuthally-averaged surface brightness profile typically traces isophotes at mu_3.6 (AB) (1 sigma) ~ 27 mag arcsec^-2, equivalent to a stellar mass surface density of ~ 1 Msun pc^-2. S^4G thus provides an unprecedented data set for the study of the distribution of mass and stellar structures in the local Universe. This paper introduces the survey, the data analysis pipeline and measurements for a first set of galaxies, observed in both the cryogenic and warm mission phase of Spitzer. For every galaxy we tabulate the galaxy diameter, position angle, axial ratio, inclination at mu_3.6 (AB) = 25.5 and 26.5 mag arcsec^-2 (equivalent to ~ mu_B (AB) =27.2 and 28.2 mag arcsec^-2, respectively). These measurements will form the initial S^4G catalog of galaxy properties. We also measure the total magnitude and the azimuthally-averaged radial profiles of ellipticity, position angle, surface brightness and color. Finally, we deconstruct each galaxy using GALFIT into its main constituent stellar components: the bulge/spheroid, disk, bar, and nuclear point source, where necessary. Together these data products will provide a comprehensive and definitive catalog of stellar structures, mass and properties of galaxies in the nearby Universe.Comment: Accepted for Publication in PASP, 14 pages, 13 figure

Space-Time Diffusion of Ground and Its Fractal Nature

We present evidences of the diffusive motion of the ground and tunnels and show that if systematic movements are excluded then the remaining uncorrelated component of the motion obeys a characteristic fractal law with the displacement variance dY^2 scaling with time- and spatial intervals T and L as dY^2 \propto T^(Alpha)L^(Gamma) with both exponents close to 1. We briefly describe experimental methods of the mesa- and microscopic ground motion detection used in the measurements at the physics research facilities sensitive to the motion, particularly, large high energy elementary particle accelerators. A simple mathematical model of the fractal motion demonstrating the observed scaling law is also presented and discussed.Comment: 83 pages, 46 fig

Morphology and environment of galaxies with disc breaks in the S4G and NIRS0S

We study the surface brightness profiles of disc galaxies in the 3.6 &mu;m images from the Spitzer Survey of Stellar Structure in Galaxies (S4G) and Ks-band images from the Near-Infrared S0-Sa galaxy Survey (NIRS0S).We particularly connect properties of single exponential (type I), downbending double exponential (type II), and upbending double exponential (type III) disc profile types, to structural components of galaxies by using detailed morphological classifications, and size measurements of rings and lenses. We also study how the local environment of the galaxies affects the profile types by calculating parameters describing the environmental density and the tidal interaction strength. We find that in majority of type II profiles the break radius is connected with structural components such as rings, lenses, and spirals. The exponential disc sections of all three profile types, when considered separately, follow the disc scaling relations. However, the outer discs of type II, and the inner discs of type III, are similar in scalelength to the single exponential discs. Although the different profile types have similar mean environmental parameters, the scalelengths of the type III profiles show a positive correlation with the tidal interaction strength. &copy; 2014 The Authors. Published by Oxford University Press on behalf of the Royal Astronomical Society.</p

Grand Design and Flocculent Spirals in the Spitzer Survey of Stellar Structure in Galaxies (S4G)

Spiral arm properties of 46 galaxies in the Spitzer Survey of Stellar Structure in Galaxies (S4G) were measured at 3.6mu, where extinction is small and the old stars dominate. The sample includes flocculent, multiple arm, and grand design types with a wide range of Hubble and bar types. We find that most optically flocculent galaxies are also flocculent in the mid-IR because of star formation uncorrelated with stellar density waves, whereas multiple arm and grand design galaxies have underlying stellar waves. Arm-interarm contrasts increase from flocculent to multiple arm to grand design galaxies and with later Hubble types. Structure can be traced further out in the disk than in previous surveys. Some spirals peak at mid-radius while others continuously rise or fall, depending on Hubble and bar type. We find evidence for regular and symmetric modulations of the arm strength in NGC 4321. Bars tend to be long, high amplitude, and flat-profiled in early type spirals, with arm contrasts that decrease with radius beyond the end of the bar, and they tend to be short, low amplitude, and exponential-profiled in late Hubble types, with arm contrasts that are constant or increase with radius. Longer bars tend to have larger amplitudes and stronger arms.Comment: 31 pages, 14 figures, ApJ in pres

HIV infection and stroke:current perspectives and future directions

HIV infection can result in stroke via several mechanisms, including opportunistic infection, vasculopathy, cardioembolism, and coagulopathy. However, the occurrence of stroke and HIV infection might often be coincidental. HIV-associated vasculopathy describes various cerebrovascular changes, including stenosis and aneurysm formation, vasculitis, and accelerated atherosclerosis, and might be caused directly or indirectly by HIV infection, although the mechanisms are controversial. HIV and associated infections contribute to chronic inflammation. Combination antiretroviral therapies (cART) are clearly beneficial, but can be atherogenic and could increase stroke risk. cART can prolong life, increasing the size of the ageing population at risk of stroke. Stroke management and prevention should include identification and treatment of the specific cause of stroke and stroke risk factors, and judicious adjustment of the cART regimen. Epidemiological, clinical, biological, and autopsy studies of risk, the pathogenesis of HIV-associated vasculopathy (particularly of arterial endothelial damage), the long-term effects of cART, and ideal stroke treatment in patients with HIV are needed, as are antiretrovirals that are without vascular risk