99 research outputs found
A social-psychological approach to conflict resolution: Interactive problem solving
Track II diplomacy has gained currency on the international scene since the last quarter of the twentieth century. Herbert C. Kelman, a leading scholar in social sciences and a pioneer in interactive conflict resolution, has contributed to this field by applying social-psychological concepts to the analysis and resolution of conflict. In this article, the conceptual basis of Kelman’s interactive problem solving approach will be appraised as well as his work on the Israeli-Palestinian conflict. The IsraeliPalestinian workshops that Kelman and his colleagues held for more than twenty years have been influential especially in the prenegotiation process leading to the Oslo Agreement
Optimal Design of Robust Combinatorial Mechanisms for Substitutable Goods
In this paper we consider multidimensional mechanism design problem for
selling discrete substitutable items to a group of buyers. Previous work on
this problem mostly focus on stochastic description of valuations used by the
seller. However, in certain applications, no prior information regarding
buyers' preferences is known. To address this issue, we consider uncertain
valuations and formulate the problem in a robust optimization framework: the
objective is to minimize the maximum regret. For a special case of
revenue-maximizing pricing problem we present a solution method based on
mixed-integer linear programming formulation
RASSF2 Is a Novel K-Ras-specific Effector and Potential Tumor Suppressor
Ras proteins regulate a wide range of biological processes by interacting with a broad assortment of effector proteins. Although activated forms of Ras are frequently associated with oncogenesis, they may also provoke growth-antagonistic effects. These include senescence, cell cycle arrest, differentiation, and apoptosis. The mechanisms that underlie these growth-inhibitory activities are relatively poorly understood. Recently, two related novel Ras effectors, NORE1 and RASSF1, have been identified as mediators of apoptosis and cell cycle arrest. Both of these proteins exhibit many of the properties normally associated with tumor suppressors. We now identify a novel third member of this family, designated RASSF2. RASSF2 binds directly to K-Ras in a GTP-dependent manner via the Ras effector domain. However, RASSF2 only weakly interacts with H-Ras. Moreover, RASSF2 promotes apoptosis and cell cycle arrest and is frequently down-regulated in lung tumor cell lines. Thus, we identify RASSF2 as a new member of the RASSF1 family of Ras effectors/tumor suppressors that exhibits a specificity for interacting with K-Ras
First-line ovulation induction for polycystic ovary syndrome : an individual participant data meta-analysis
Acknowledgements We would like to thank Mr M. Draper from Barr Smith Library, University of Adelaide, for his assistance in developing the search strategies and Dr M. H. Zafarmand from University of Amsterdam for assisting with the translation. We would like to acknowledge all the investigators and participants of the primary trials. The investigators of individual trials are listed in Supplementary Table SIV. We would like to acknowledge the assistance of NICHD, the Reproductive Medicine Network (RMN) and the Protocol Subcommittee, in making the database for PPCOS I and II available. +The authors of the Reproductive Medicine Network are R.S.L., R.G. Brzyski, M.P. Diamond, C. Coutifaris, W.D. Schlaff, P. Casson, G.M. Christman, H. Huang, Q. Yan, R. Alvero, D.J. Haisenleder, K.T. Barnhart, G.W. Bates, R. Usadi, S. Lucidi, V. Baker, J.C. Trussell, S.A. Krawetz, P. Snyder, D. Ohl, N. Santoro, H.X. Barnhart, B.R. Carr, S.A. Carson, M.P. Steinkampf, P.G. McGovern, N.A. Cataldo, G.G. Gosman, J.E. Nestler, L.C. Giudice, P.C. Leppert, E.R. Myers, E. Eisenberg and H. Zhang. The details of their affiliations and NIH Grants are listed in Supplementary Table SV. Funding An Australian government research training programme scholarship (to R.W.); Australian National Health and Medical Research Council-funded Centre for Research Excellence in Polycystic Ovary Syndrome (APP1078444). The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript.Peer reviewedPostprin
Swift trust and commitment: the missing links for humanitarian supply chain coordination?
Coordination among actors in a humanitarian relief supply chain decides whether a relief operation can be or successful or not. In humanitarian supply chains, due to the urgency and importance of the situation combined with scarce resources, actors have to coordinate and trust each other in order to achieve joint goals. This paper investigated empirically the role of swift trust as mediating variable for achieving supply chain coordination. Based on commitment-trust theory we explore enablers of swift-trust and how swift trust translates into coordination through commitment. Based on a path analytic model we test data from the National Disaster Management Authority of India. Our study is the first testing commitment-trust theory (CTT) in the humanitarian context, highlighting the importance of swift trust and commitment for much thought after coordination. Furthermore, the study shows that information sharing and behavioral uncertainty reduction act as enablers for swift trust. The study findings offer practical guidance and suggest that swift trust is a missing link for the success of humanitarian supply chains
Slaughter weight rather than sex affects carcass cuts and tissue composition of Bisaro pigs
Carcass cuts and tissue composition were assessed in Bisaro pigs (n=64) from two sexes (31 gilts and 33 entire
males) reared until three target slaughter body-weights (BW) means: 17 kg, 32 kg, and 79 kg. Dressing percentage
and backfat thickness increased whereas carcass shrinkage decreased with increasing BW. Slaughter
weight affected most of the carcass cut proportions, except shoulder and thoracic regions. Bone proportion
decreased linearly with increasing slaughter BW, while intermuscular and subcutaneous adipose tissue depots
increased concomitantly. Slaughter weight increased the subcutaneous adipose tissue proportion but this impaired
intramuscular and intermuscular adipose tissues in the loin primal. The sex of the pigs minimally affected
the carcass composition, as only the belly weight and the subcutaneous adipose tissue proportions were greater
in gilts than in entire males. Light pigs regardless of sex are recommended to balance the trade-offs between
carcass cuts and their non-edible compositional outcomes.Work included in the Portuguese PRODER research Project
BISOPORC – Pork extensive production of Bísara breed, in two alternative
systems: fattening on concentrate vs chesnut, Project PRODER SI
I&DT Medida 4.1 “Cooperação para a Inovação”. The authors are
grateful to Laboratory of Carcass and Meat Quality of Agriculture
School of Polytechnic Institute of Bragança ‘Cantinho do Alfredo’. The
authors are members of the MARCARNE network, funded by CYTED
(ref. 116RT0503).info:eu-repo/semantics/publishedVersio
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
The roots of research in (political) persuasion: Ethos, pathos, logos and the Yale studies of persuasive communications
In ancient Greece, Aristotle claimed in his Rhetoric that the function of rhetoric was not to persuade, but to discover the means of persuasion in each case. It is remarkable how the empirical approach towards persuasion embedded in ‘ethos, pathos, logos’ of Aristotle seems to be revisited by the Yale study group in 1950s, with the aim of discovering the laws of persuasive communications in laboratory settings. The contemporary quest carried out by the Yale research program on persuasion reflects the Aristotelean tradition of examining ‘the ethos, pathos and logos’ aspects of persuasion closely. This article aims to draw the reader’s attention to this strong influence of Aristotle’s perspective on the Yale research group. Adopting a learning theory approach, the Yale study group, led by psychologist Carl Hovland, tried to find out the stimulus-response effects of many variables concerning persuasion and thus paved the way for more elaborate research in persuasion in the years to come. The characteristics of the elements of persuasion, which have been studied by the Yale research group, are explained in this article by giving examples from their experimental research. The major contribution of Hovland and his colleagues has been the specification of an initial set of characteristics to understand the principles and processes of persuasion. Since persuasion is an important dimension of politics in general and negotiation/conflict resolution in particular, the tradition of studying (political) rhetoric deserves the attention of disciplines like political science and international relations as well
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