44 research outputs found

    Imágenes de la Guerra Civil española en la poesía de expresión inglesa

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    La Guerra Civil Española entusiasmó la imaginación creadora de los intelectuales en general y de los poetas ingleses en particular. Ensayos, novelas, obras teatrales, artículos de periódicos..., proliferaron durante los tres años que duró la guerra. Muchos escritores llegaron a España para seguir los acontecimientos más de cerca, y muchos perdieron sus vidas en el campo de batalla. Pero el impacto emocional de la guerra puede verse especialmente en la poesía. Un buen número de poetas de habla inglesa -ingleses, irlandeses, norteamericanos, etc., producen una enorme cantidad de poemas que van desde contenidos de clara declaración política al lirismo más íntimo.The Spanish Civil War greatly excited the creative imagination of intellectuals in general and of English poets in particular. Essays, novels, theatrical works, newspaper articles, and son on, proliferated during the three years that the war lasted. Many writers came to Spain to follow the events more closely, and a good many lost their lives on the battlefield. But the emotional impact of the war can be seen especially in poetry. A good number of English-speaking poets -British, Irish, North American, etc.-produced an enormous quantity of poems ranging in content from bald political statement to the most intimate lyricism

    Impact of Blood Eosinophil Variability in Asthma:A Real-Life Population Study

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    RATIONALE: Blood eosinophil count predicts response to inhaled corticosteroids and specific biologic therapies in selected asthma patients. Despite this important role, fundamental aspects of eosinophil behavior in asthma have not been studied. Objectives To investigate the behavior of blood eosinophils in a population comparing their distribution with the general population and studying their intra-individual variability over time in relation to hospital episodes (emergency department visits and hospitalizations) in clinical practice. METHODS: The distribution and variability of 35,703 eosinophil determinations in 10,059 stable asthma patients were investigated in the Majorca Real-Life Investigation in COPD and Asthma cohort (MAJORICA). Eosinophil distribution in the asthma population was compared with a control sample from the general population of 8,557 individuals. Eosinophil variability and hospital episodes were analyzed using correlations, ROC curves and multiple regression analysis. We defined the Eosinophil Variability Index (EVI) as (Eosmax-Eosmin/Eosmax) x 100%. The findings of the asthma population were re-tested in an external well-characterized asthma cohort. RESULTS: The eosinophil count values and variability were higher in the asthma population than in the general population (p-value<0.001). Variability data showed a better association with hospital episodes than the counting values. An EVI≥50% was more strongly associated with hospital episodes than any of the absolute counting values. These results were validated in the external cohort. CONCLUSION: The eosinophil variability in asthma patients better identifies the risk of any hospital episode than the absolute counting values currently used to target specific treatments

    Effectiveness of a strategy that uses educational games to implement clinical practice guidelines among Spanish residents of family and community medicine (e-EDUCAGUIA project):A clinical trial by clusters

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    This study was funded by the Fondo de Investigaciones Sanitarias FIS Grant Number PI11/0477 ISCIII.-REDISSEC Proyecto RD12/0001/0012 AND FEDER Funding.Background: Clinical practice guidelines (CPGs) have been developed with the aim of helping health professionals, patients, and caregivers make decisions about their health care, using the best available evidence. In many cases, incorporation of these recommendations into clinical practice also implies a need for changes in routine clinical practice. Using educational games as a strategy for implementing recommendations among health professionals has been demonstrated to be effective in some studies; however, evidence is still scarce. The primary objective of this study is to assess the effectiveness of a teaching strategy for the implementation of CPGs using educational games (e-learning EDUCAGUIA) to improve knowledge and skills related to clinical decision-making by residents in family medicine. The primary objective will be evaluated at 1 and 6months after the intervention. The secondary objectives are to identify barriers and facilitators for the use of guidelines by residents of family medicine and to describe the educational strategies used by Spanish teaching units of family and community medicine to encourage implementation of CPGs. Methods/design: We propose a multicenter clinical trial with randomized allocation by clusters of family and community medicine teaching units in Spain. The sample size will be 394 residents (197 in each group), with the teaching units as the randomization unit and the residents comprising the analysis unit. For the intervention, both groups will receive an initial 1-h session on clinical practice guideline use and the usual dissemination strategy by e-mail. The intervention group (e-learning EDUCAGUIA) strategy will consist of educational games with hypothetical clinical scenarios in a virtual environment. The primary outcome will be the score obtained by the residents on evaluation questionnaires for each clinical practice guideline. Other included variables will be the sociodemographic and training variables of the residents and the teaching unit characteristics. The statistical analysis will consist of a descriptive analysis of variables and a baseline comparison of both groups. For the primary outcome analysis, an average score comparison of hypothetical scenario questionnaires between the EDUCAGUIA intervention group and the control group will be performed at 1 and 6months post-intervention, using 95% confidence intervals. A linear multilevel regression will be used to adjust the model. Discussion: The identification of effective teaching strategies will facilitate the incorporation of available knowledge into clinical practice that could eventually improve patient outcomes. The inclusion of information technologies as teaching tools permits greater learning autonomy and allows deeper instructor participation in the monitoring and supervision of residents. The long-term impact of this strategy is unknown; however, because it is aimed at professionals undergoing training and it addresses prevalent health problems, a small effect can be of great relevance. Trial registration: ClinicalTrials.gov: NCT02210442.Publisher PDFPeer reviewe

    Global urban environmental change drives adaptation in white clover.

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    Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural clines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale

    4to. Congreso Internacional de Ciencia, Tecnología e Innovación para la Sociedad. Memoria académica

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    Este volumen acoge la memoria académica de la Cuarta edición del Congreso Internacional de Ciencia, Tecnología e Innovación para la Sociedad, CITIS 2017, desarrollado entre el 29 de noviembre y el 1 de diciembre de 2017 y organizado por la Universidad Politécnica Salesiana (UPS) en su sede de Guayaquil. El Congreso ofreció un espacio para la presentación, difusión e intercambio de importantes investigaciones nacionales e internacionales ante la comunidad universitaria que se dio cita en el encuentro. El uso de herramientas tecnológicas para la gestión de los trabajos de investigación como la plataforma Open Conference Systems y la web de presentación del Congreso http://citis.blog.ups.edu.ec/, hicieron de CITIS 2017 un verdadero referente entre los congresos que se desarrollaron en el país. La preocupación de nuestra Universidad, de presentar espacios que ayuden a generar nuevos y mejores cambios en la dimensión humana y social de nuestro entorno, hace que se persiga en cada edición del evento la presentación de trabajos con calidad creciente en cuanto a su producción científica. Quienes estuvimos al frente de la organización, dejamos plasmado en estas memorias académicas el intenso y prolífico trabajo de los días de realización del Congreso Internacional de Ciencia, Tecnología e Innovación para la Sociedad al alcance de todos y todas

    Global urban environmental change drives adaptation in white clover

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    Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural clines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale

    Imágenes de la Guerra Civil española en la poesía de expresión inglesa

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    La Guerra Civil Española entusiasmó la imaginación creadora de los intelectuales en general y de los poetas ingleses en particular. Ensayos, novelas, obras teatrales, artículos de periódicos..., proliferaron durante los tres años que duró la guerra. Muchos escritores llegaron a España para seguir los acontecimientos más de cerca, y muchos perdieron sus vidas en el campo de batalla. Pero el impacto emocional de la guerra puede verse especialmente en la poesía. Un buen número de poetas de habla inglesa -ingleses, irlandeses, norteamericanos, etc., producen una enorme cantidad de poemas que van desde contenidos de clara declaración política al lirismo más íntimo.The Spanish Civil War greatly excited the creative imagination of intellectuals in general and of English poets in particular. Essays, novels, theatrical works, newspaper articles, and son on, proliferated during the three years that the war lasted. Many writers came to Spain to follow the events more closely, and a good many lost their lives on the battlefield. But the emotional impact of the war can be seen especially in poetry. A good number of English-speaking poets -British, Irish, North American, etc.-produced an enormous quantity of poems ranging in content from bald political statement to the most intimate lyricism

    Co-movimientos entre los Índices Accionarios y los Ciclos Económicos de Estados Unidos y México

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    Abstract The aim of this paper is to identify the co-movements between the Dow Jones stock index (DJ) of the United States of America (US) and the Índice de Precios y Cotizaciones (IPC) of Mexico along with the economic cycles of both countries. A novel approach using concepts and models widely accepted in the study of economic cycles is developed to explain this relationship, in particular: trend, cycle, turning points, conformity and synchrony. Finding points show that trend of the DJ index and the mexican economy indicator (SICCA) present high conformity. On the other hand, the financial cycles of the DJ and IPC present an almost coincident synchrony. Some variables such as exchange rate, credit and political cycles that also influence economic cycles are not taken into account. The originality of this paper is the study of the relationship between financial cycles obtained from the main stock indexes and economic cycles. It is concluded that the cycles of the DJ and IPC anticipate economic cycles of both US and Mexico with at least four months.Resumen El objetivo de este trabajo es identificar los co-movimientos entre los índices accionarios Dow Jones (DJ) de los Estados Unidos (EU) y el Índice de Precios y Cotizaciones (IPC) de México; así también con los ciclos económicos de ambos países. Para explicar esta relación se propone una metodología que comprende conceptos y modelos utilizados en el estudio de ciclos económicos, en particular: tendencia, ciclo, puntos de giro, conformidad y sincronía. Los resultados muestran que las tendencias del índice DJ y el indicador de la economía mexicana (SICCA) muestran una alta conformidad. Por otra parte, los ciclos financieros del DJ e IPC presentan una sincronía casi coincidente. Algunas variables que escapan a este trabajo y que también influyen en los ciclos económicos incluyen la tasa de cambio, ciclos crediticios y políticos. La originalidad de esta investigación consiste en el estudio de la relación que tienen los ciclos financieros obtenidos de los principales índices accionarios con los ciclos económicos. Se concluye que los ciclos del DJ e IPC anticipan con al menos cuatro meses a los ciclos económicos de EU y México
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