699 research outputs found
Theory and Practice of Data Citation
Citations are the cornerstone of knowledge propagation and the primary means
of assessing the quality of research, as well as directing investments in
science. Science is increasingly becoming "data-intensive", where large volumes
of data are collected and analyzed to discover complex patterns through
simulations and experiments, and most scientific reference works have been
replaced by online curated datasets. Yet, given a dataset, there is no
quantitative, consistent and established way of knowing how it has been used
over time, who contributed to its curation, what results have been yielded or
what value it has.
The development of a theory and practice of data citation is fundamental for
considering data as first-class research objects with the same relevance and
centrality of traditional scientific products. Many works in recent years have
discussed data citation from different viewpoints: illustrating why data
citation is needed, defining the principles and outlining recommendations for
data citation systems, and providing computational methods for addressing
specific issues of data citation.
The current panorama is many-faceted and an overall view that brings together
diverse aspects of this topic is still missing. Therefore, this paper aims to
describe the lay of the land for data citation, both from the theoretical (the
why and what) and the practical (the how) angle.Comment: 24 pages, 2 tables, pre-print accepted in Journal of the Association
for Information Science and Technology (JASIST), 201
Models of everywhere revisited: a technological perspective
The concept ‘models of everywhere’ was first introduced in the mid 2000s as a means of reasoning about the
environmental science of a place, changing the nature of the underlying modelling process, from one in which
general model structures are used to one in which modelling becomes a learning process about specific places, in
particular capturing the idiosyncrasies of that place. At one level, this is a straightforward concept, but at another
it is a rich multi-dimensional conceptual framework involving the following key dimensions: models of everywhere,
models of everything and models at all times, being constantly re-evaluated against the most current
evidence. This is a compelling approach with the potential to deal with epistemic uncertainties and nonlinearities.
However, the approach has, as yet, not been fully utilised or explored. This paper examines the
concept of models of everywhere in the light of recent advances in technology. The paper argues that, when first
proposed, technology was a limiting factor but now, with advances in areas such as Internet of Things, cloud
computing and data analytics, many of the barriers have been alleviated. Consequently, it is timely to look again
at the concept of models of everywhere in practical conditions as part of a trans-disciplinary effort to tackle the
remaining research questions. The paper concludes by identifying the key elements of a research agenda that
should underpin such experimentation and deployment
Addendum to Informatics for Health 2017: Advancing both science and practice
This article presents presentation and poster abstracts that were mistakenly omitted from the original publication
MULTI-X, a State-of-the-Art Cloud-Based Ecosystem for Biomedical Research
With the exponential growth of clinical data, and the fast development of AI technologies, researchers are facing unprecedented challenges in managing data storage, scalable processing, and analysis capabilities for heterogeneous multisourced datasets. Beyond the complexity of executing data-intensive workflows over large-scale distributed data, the reproducibility of computed results is of paramount importance to validate scientific discoveries. In this paper, we present MULTIX, a cross-domain research-oriented platform, designed for collaborative and reproducible science. This cloud-based framework simplifies the logistical challenges of implementing data analytics and AI solutions by providing pre-configured environments with ad-hoc scalable computing resources and secure distributed storage, to efficiently build, test, share and reproduce scientific pipelines. An exemplary use-case in the area of cardiac image analysis will be presented together with the practical application of the platform for the analysis of ~20.000 subjects of the UK-Biobank database
Measuring Success for a Future Vision: Defining Impact in Science Gateways/Virtual Research Environments
Scholars worldwide leverage science gateways/VREs for a wide variety of research and education endeavors spanning diverse scientific fields. Evaluating the value of a given science gateway/VRE to its constituent community is critical in obtaining the financial and human resources necessary to sustain operations and increase adoption in the user community. In this paper, we feature a variety of exemplar science gateways/VREs and detail how they define impact in terms of e.g., their purpose, operation principles, and size of user base. Further, the exemplars recognize that their science gateways/VREs will continuously evolve with technological advancements and standards in cloud computing platforms, web service architectures, data management tools and cybersecurity. Correspondingly, we present a number of technology advances that could be incorporated in next-generation science gateways/VREs to enhance their scope and scale of their operations for greater success/impact. The
exemplars are selected from owners of science gateways in the Science Gateways Community Institute (SGCI) clientele in the United States, and from the owners of VREs in the International Virtual Research Environment Interest Group (VRE-IG) of the Research Data Alliance. Thus, community-driven best practices and technology advances are compiled from diverse expert groups with an international perspective
to envisage futuristic science gateway/VRE innovations
AI in Medical Imaging Informatics: Current Challenges and Future Directions
This paper reviews state-of-the-art research solutions across the spectrum of medical imaging informatics, discusses clinical translation, and provides future directions for advancing clinical practice. More specifically, it summarizes advances in medical imaging acquisition technologies for different modalities, highlighting the necessity for efficient medical data management strategies in the context of AI in big healthcare data analytics. It then provides a synopsis of contemporary and emerging algorithmic methods for disease classification and organ/ tissue segmentation, focusing on AI and deep learning architectures that have already become the de facto approach. The clinical benefits of in-silico modelling advances linked with evolving 3D reconstruction and visualization applications are further documented. Concluding, integrative analytics approaches driven by associate research branches highlighted in this study promise to revolutionize imaging informatics as known today across the healthcare continuum for both radiology and digital pathology applications. The latter, is projected to enable informed, more accurate diagnosis, timely prognosis, and effective treatment planning, underpinning precision medicine
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