18,116 research outputs found
Agents in Bioinformatics
The scope of the Technical Forum Group (TFG) on Agents in Bioinformatics (BIOAGENTS) was to inspire collaboration between the agent and bioinformatics communities with the aim of creating an opportunity to propose a different (agent-based) approach to the development of computational frameworks both for data analysis in bioinformatics and for system modelling in computational biology. During the day, the participants examined the future of research on agents in bioinformatics primarily through 12 invited talks selected to cover the most relevant topics. From the discussions, it became clear that there are many perspectives to the field, ranging from bio-conceptual languages for agent-based simulation, to the definition of bio-ontology-based declarative languages for use by information agents, and to the use of Grid agents, each of which requires further exploration. The interactions between participants encouraged the development of applications that describe a way of creating agent-based simulation models of biological systems, starting from an hypothesis and inferring new knowledge (or relations) by mining and analysing the huge amount of public biological data. In this report we summarise and reflect on the presentations and discussions
An Ontology Approach for Knowledge Acquisition and Development of Health Information System (HIS)
This paper emphasizes various knowledge acquisition approaches in terms of tacit and explicit knowledge management that can be helpful to capture, codify and communicate within medical unit. The semantic-based knowledge management system (SKMS) supports knowledge acquisition and incorporates various approaches to provide systematic practical platform to knowledge practitioners and to identify various roles of healthcare professionals, tasks that can be performed according to personnelâs competencies, and activities that are carried out as a part of tasks to achieve defined goals of clinical process. This research outcome gives new vision to IT practitioners to manage the tacit and implicit knowledge in XML format which can be taken as foundation for the development of information systems (IS) so that domain end-users can receive timely healthcare related services according to their demands and needs
TumorML: Concept and requirements of an in silico cancer modelling markup language
This paper describes the initial groundwork carried out as part of the European Commission funded Transatlantic Tumor Model Repositories project, to develop a new markup language for computational cancer modelling, TumorML. In this paper we describe the motivations for such a language, arguing that current state-of-the-art biomodelling languages are not suited to the cancer modelling domain. We go on to describe the work that needs to be done to develop TumorML, the conceptual design, and a description of what existing markup languages will be used to compose the language specification
Systems approaches to modelling pathways and networks.
Peer reviewedPreprin
The Requirements for Ontologies in Medical Data Integration: A Case Study
Evidence-based medicine is critically dependent on three sources of
information: a medical knowledge base, the patients medical record and
knowledge of available resources, including where appropriate, clinical
protocols. Patient data is often scattered in a variety of databases and may,
in a distributed model, be held across several disparate repositories.
Consequently addressing the needs of an evidence-based medicine community
presents issues of biomedical data integration, clinical interpretation and
knowledge management. This paper outlines how the Health-e-Child project has
approached the challenge of requirements specification for (bio-) medical data
integration, from the level of cellular data, through disease to that of
patient and population. The approach is illuminated through the requirements
elicitation and analysis of Juvenile Idiopathic Arthritis (JIA), one of three
diseases being studied in the EC-funded Health-e-Child project.Comment: 6 pages, 1 figure. Presented at the 11th International Database
Engineering & Applications Symposium (Ideas2007). Banff, Canada September
200
Pemilihan kerjaya di kalangan pelajar aliran perdagangan sekolah menengah teknik : satu kajian kes
This research is a survey to determine the career chosen of form four student
in commerce streams. The important aspect of the career chosen has been divided
into three, first is information about career, type of career and factor that most
influence students in choosing a career. The study was conducted at Sekolah
Menengah Teknik Kajang, Selangor Darul Ehsan. Thirty six form four students was
chosen by using non-random sampling purpose method as respondent. All
information was gather by using questionnaire. Data collected has been analyzed in
form of frequency, percentage and mean. Results are performed in table and graph.
The finding show that information about career have been improved in students
career chosen and mass media is the main factor influencing students in choosing
their career
Towards engineering ontologies for cognitive profiling of agents on the semantic web
Research shows that most agent-based collaborations
suffer from lack of flexibility. This is due to the fact that
most agent-based applications assume pre-defined
knowledge of agentsâ capabilities and/or neglect basic
cognitive and interactional requirements in multi-agent
collaboration. The highlight of this paper is that it brings
cognitive models (inspired from cognitive sciences and HCI)
proposing architectural and knowledge-based requirements
for agents to structure ontological models for cognitive
profiling in order to increase cognitive awareness between
themselves, which in turn promotes flexibility, reusability
and predictability of agent behavior; thus contributing
towards minimizing cognitive overload incurred on humans.
The semantic web is used as an action mediating space,
where shared knowledge base in the form of ontological
models provides affordances for improving cognitive
awareness
Agents in bioinformatics, computational and systems biology
The adoption of agent technologies and multi-agent systems constitutes an emerging area in bioinformatics. In this
article, we report on the activity of the Working Group on Agents in Bioinformatics (BIOAGENTS) founded during
the first AgentLink III Technical Forum meeting on the 2nd of July, 2004, in Rome. The meeting provided an
opportunity for seeding collaborations between the agent and bioinformatics communities to develop a different
(agent-based) approach of computational frameworks both for data analysis and management in bioinformatics and
for systems modelling and simulation in computational and systems biology.The collaborations gave rise to applica-
tions and integrated tools that we summarize and discuss in context of the state of the art in this area.
We investigate on future challenges and argue that the field should still be explored from many perspectives ranging
from bio-conceptual languages for agent-based simulation, to the definition of bio-ontology-based declarative
languages to be used by information agents, and to the adoption of agents for computational grid
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