An exploratory investigation into the role of a research and development programme on future craft practice

Purpose - The purpose of this paper is to assess the effectiveness of a research and development programme on improving craft practice through the provision of mentoring by academic practitioners, studio space and advice on marketing techniques. Design/methodology/approach - Following an initial focus group investigation of issues which impinge on contemporary craft practice, recipients of a bursary associated with the research and development programme were assessed with respect to how their craft and marketing competencies have developed. Findings - Practitioners can now reflect on their skills, experiment with techniques and consider the effectiveness of their approach and attitude towards marketing. Research limitations/implications - The programme only extends to practitioners working with one art and design institution but has implications for those concerned with creative practice elsewhere. Practical implications - There is wider potential to reinvigorate artistic and marketing practice across the creative and cultural industries, and the small and medium enterprise community in general. Originality/value - This is a novel programme which challenges experienced practitioners to extend their creative abilities in craft and approaches to marketing

Intra-Tester Reliability and Concurrent Validity of Musculoskeletal Ultrasound and Vernier Calipre in Quantifying the Anteroposterior Diameter of the Common Extensor Origin of the Forearm and the Radial Nerve: A Cadaveric Study

Introduction: The literature reports an increase in anteroposterior diameter of the common extensor origin (CEO) of the extensor carpi radialis brevis (ECRB) and extensor digitorum communis (EDC) or the radial nerve in painful elbows diagnosed with lateral epicondylalgia (LE) or supinator syndrome. The edge-to-edge measurements of these anatomical structures are quantified using musculoskeletal ultrasound (MSUS). However, in the current literature, reports on the reliability and validity of MSUS measurements of the CEO (of ECRB and EDC) and the radial nerve are not found. In this study, reliability was measured for three testers in determining the anteroposterior diameter of the CEO (of ECRB and EDC) and the radial nerve. Moreover, the concurrent validity was determined of MSUS measurements with Vernier calipre measurements using formalin preserved elbows of human cadavers. Methodology: Cadaver measurements of the CEO (of ECRB and EDC) and the radial nerve were performed. Initially, the sonologist measured the anteroposterior diameter of the CEO (of ECRB and EDC) and the radial nerve. A month after scan, the formalin preserved cadavers were dissected. Consequently, the anteroposterior diameter of the exposed CEO (of ECRB and EDC) and the radial nerve was measured using the Vernier calipre. Results: Eight upper extremities of four embalmed Filipino cadavers (2 males: 2 females) were dissected. A total of seven (7) CEO of EDC, seven (7) CEO of ECRB, and eight (8) radial nerves at the level of the radial head in the elbows of four (4) cadavers were measured using the MSUS and the Vernier calipre. The MSUS and Vernier calipre protocol used in this study was found to be reliable, p \u3e 0.05. However, in all three levels of interest, the MSUS measurements were statistically different from the Vernier calipre measurements, p \u3c 0.05. Conclusion: MSUS and Vernier calipre measurements are reliable methods in measuring the CEO (of ECRB and EDC) and the radial nerve. While each of these methods is reliable in measuring the anteroposterior dimensions of the CEO (of the EDC and ECRB) and the radial nerve, substituting one for the other yielded statistically different measurement results

Quasi-experimental study designs series –Paper 9: Collecting Data from Quasi-Experimental Studies

Objective: To identify variables that must be coded when synthesizing primary studies that use quasi-experimental designs.  Study Design and Setting: All quasi-experimental (QE) designs.  Results: When designing a systematic review of QE studies potential sources of heterogeneity – both theory-based and methodological – must be identified. We outline key components of inclusion criteria for syntheses of quasi-experimental studies. We provide recommendations for coding content-relevant and methodological variables, and outlined the distinction between bivariate effect sizes and partial (i.e., adjusted) effect sizes. Designs used and controls employed are viewed as of greatest importance. Potential sources of bias and confounding are also addressed.  Conclusion: Careful consideration must be given to inclusion criteria and the coding of theoretical and methodological variables during the design phase of a synthesis of quasi-experimental studies. The success of the meta-regression analysis relies on the data available to the meta-analyst. Omission of critical moderator variables (i.e., effect modifiers) will undermine the conclusions of a meta-analysis

Likelihood and Cost Impact of Engineering Change Requirements for DoD Contracts

Purpose: There appears to be no empirical-based method in the literature for estimating if an engineering change proposal (ECP) will occur or the dollar amount incurred. This paper aims to present an empirically based approach to address this shortfall.Design/Methodology/Approach: Using the cost assessment data enterprise database, 533 contracts were randomly selected via a stratified sampling plan to build two regression models: one to predict the likelihood of a contract experiencing an ECP and the other to determine the expected median per cent increase in baseline contract cost if an ECP was likely. Both models adopted a stepwise approach. A validation set was placed aside prior to any model building.Findings: Not every contract incurs an ECP; approximately 80 per cent of the contracts in the database did not have an ECP. The likelihood of an ECP and the additional amount incurred appears to be statistically independent of acquisition phase, branch of service, commodity, contract type or any other factor except for the basic contract amount and the number of contract line item numbers; both of these later variables equally affected the contract percentage increase because of an ECP. The combined model overall bested current anecdotal approaches to ECP withhold

Evaluation and application of static headspace-multicapillary column-gas chromatography-ion mobility spectrometry for complex sample analysis.

An evaluation of static headspace-multicapillary column-gas chromatography-ion mobility spectrometry (SHS-MCC-GC-IMS) has been undertaken to assess its applicability for the determination of 32 volatile compounds (VCs). The key experimental variables of sample incubation time and temperature have been evaluated alongside the MCC-GC variables of column polarity, syringe temperature, injection temperature, injection volume, column temperature and carrier gas flow rate coupled with the IMS variables of temperature and drift gas flow rate. This evaluation resulted in six sets of experimental variables being required to separate the 32 VCs. The optimum experimental variables for SHS-MCC-GC-IMS, the retention time and drift time operating parameters were determined; to normalise the operating parameters, the relative drift time and normalised reduced ion mobility for each VC were determined. In addition, a full theoretical explanation is provided on the formation of the monomer, dimer and trimer of a VC. The optimum operating condition for each VC calibration data was obtained alongside limit of detection (LOD) and limit of quantitation (LOQ) values. Typical detection limits ranged from 0.1ng bis(methylthio)methane, ethylbutanoate and (E)-2-nonenal to 472ng isovaleric acid with correlation coefficient (R(2)) data ranging from 0.9793 (for the dimer of octanal) through to 0.9990 (for isobutyric acid). Finally, the developed protocols were applied to the analysis of malodour in sock samples. Initial work involved spiking an inert matrix and sock samples with appropriate concentrations of eight VCs. The average recovery from the inert matrix was 101±18% (n=8), while recoveries from the sock samples were lower, that is, 54±30% (n=8) for sock type 1 and 78±24% (n=6) for sock type 2. Finally, SHS-MCC-GC-IMS was applied to sock malodour in a field trial based on 11 volunteers (mixed gender) over a 3-week period. By applying the SHS-MCC-GC-IMS database, four VCs were identified and quantified: ammonia, dimethyl disulphide, dimethyl trisulphide and butyric acid. A link was identified between the presence of high ammonia and dimethyl disulphide concentrations and a high malodour odour grading, that is, ≥ 6. Statistical analysis did not find any correlation between the occurrence of dimethyl disulphide and participant gender

Cross-cultural effects of color, but not morphological masculinity, on perceived attractiveness of men's faces

This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2012 ElsevierMuch attractiveness research has focused on face shape. The role of masculinity (which for adults is thought to be a relatively stable shape cue to developmental testosterone levels) in male facial attractiveness has been examined, with mixed results. Recent work on the perception of skin color (a more variable cue to current health status) indicates that increased skin redness, yellowness, and lightness enhance apparent health. It has been suggested that stable cues such as masculinity may be less important to attractiveness judgments than short-term, more variable health cues. We examined associations between male facial attractiveness, masculinity, and skin color in African and Caucasian populations. Masculinity was not found to be associated with attractiveness in either ethnic group. However, skin color was found to be an important predictor of attractiveness judgments, particularly for own-ethnicity faces. Our results suggest that more plastic health cues, such as skin color, are more important than developmental cues such as masculinity. Further, unfamiliarity with natural skin color variation in other ethnic groups may limit observers' ability to utilize these color cues

Preliminary measurements of turbulence and environmental parameters in a sub-tropical estuary of Eastern Australia

In natural systems, mixing is driven by turbulence, but current knowledge is very limited in estuarine zones where predictions of contaminant dispersion are often inaccurate. A series of detailed field studies was conducted in a small subtropical creek in eastern Australia. Hydrodynamic, physio-chemical and ecological measurements were conducted simultaneously to assess the complexity of the estuarine zone and the interactions between turbulence and environment. The measurements were typically performed at high frequency over a tidal cycle. The results provide an original data set to complement long-term monitoring and the basis for a more detailed study of mixing in sub-tropical systems. Unlike many long-term observations, velocity and water quality scalars were measured herein with sufficient spatial and temporal resolutions to determine quantities of interest in the study of turbulence, while ecological indicators were sampled systematically and simultaneously. In particular the results yielded contrasted outcomes, and the finding impacts on the selection process for key water quality indicators

Vaccinia protein 169 inhibits translation and affects virulence

Vaccinia virus (VACV) is the prototypic orthopoxvirus and the vaccine used to eradicate smallpox. Here we show that VACV strain Western Reserve protein 169 is a cytoplasmic polypeptide expressed early during infection that is excluded from virus factories and inhibits the initiation of cap-dependent and cap-independent translation. Ectopic expression of protein 169 causes the accumulation of 80S ribosomes, a reduction of polysomes, and inhibition of protein expression deriving from activation of multiple innate immune signaling pathways. A virus lacking 169 (vΔ169) replicates and spreads normally in cell culture but is more virulent than parental and revertant control viruses in intranasal and intradermal murine models of infection. Intranasal infection by vΔ169 caused increased pro-inflammatory cytokines and chemokines, infiltration of pulmonary leukocytes, and lung weight. These alterations in innate immunity resulted in a stronger CD8+ T-cell memory response and better protection against virus challenge. This work illustrates how inhibition of host protein synthesis can be a strategy for virus suppression of innate and adaptive immunity.This work was supported by grants from the Wellcome Trust (090315) and the UK Medical Research Council (G0800151). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.This is the final version of the article. It first appeared from PLOS via http://dx.doi.org/10.1371/journal.ppat.100515

Sequential Effects in Judgements of Attractiveness: The Influences of Face Race and Sex

In perceptual decision-making, a person’s response on a given trial is influenced by their response on the immediately preceding trial. This sequential effect was initially demonstrated in psychophysical tasks, but has now been found in more complex, real-world judgements. The similarity of the current and previous stimuli determines the nature of the effect, with more similar items producing assimilation in judgements, while less similarity can cause a contrast effect. Previous research found assimilation in ratings of facial attractiveness, and here, we investigated whether this effect is influenced by the social categories of the faces presented. Over three experiments, participants rated the attractiveness of own- (White) and other-race (Chinese) faces of both sexes that appeared successively. Through blocking trials by race (Experiment 1), sex (Experiment 2), or both dimensions (Experiment 3), we could examine how sequential judgements were altered by the salience of different social categories in face sequences. For sequences that varied in sex alone, own-race faces showed significantly less opposite-sex assimilation (male and female faces perceived as dissimilar), while other-race faces showed equal assimilation for opposite- and same-sex sequences (male and female faces were not differentiated). For sequences that varied in race alone, categorisation by race resulted in no opposite-race assimilation for either sex of face (White and Chinese faces perceived as dissimilar). For sequences that varied in both race and sex, same-category assimilation was significantly greater than opposite-category. Our results suggest that the race of a face represents a superordinate category relative to sex. These findings demonstrate the importance of social categories when considering sequential judgements of faces, and also highlight a novel approach for investigating how multiple social dimensions interact during decision-making