12 research outputs found

    The Scintillation Index In Moderate To Strong Turbulence For The Gaussian Beam Wave Along A Slant Path

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    Scintillation is one of the most common statistics in the literature of mathematical modeling of laser propagation through random media. One approach to estimating scintillation is through the Rytov approximation, which is limited to weak atmospheric turbulence. Recently, an improvement of the Rytov approximation was developed employing a linear filter function technique. This modifies the Rytov approximation and extends the validity into the moderate to strong regime. In this work, an expression governing scintillation of a Gaussian beam along an uplink slant path valid in all regimes of turbulence is presented, as well as results for the limiting cases of a plane wave and a spherical wave

    New genetic loci link adipose and insulin biology to body fat distribution.

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    Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms
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