Promotional Flyer for Exhibit - Rituals of Healing: Body, Mind, Spirit

Exhibit dates: Feb. 8 through April 20, 2023, Stuart and Mimi Rose Gallery and Marian Library Gallery, both in Roesch Library. Rose Gallery: University of Dayton first-year students in Professor Liz Hutter’s writing seminar curated this display of artifacts from the Marian Library collections. While practicing writing as a model of inquiry and discovery, students wrote narratives to explore what individuals or groups believe about religion, medical expertise, and healing of the body, mind and spirit. Marian Library Gallery: Materials included in this section of the exhibit feature Mary’s roles in health, healing and rituals — including tarot cards, Catalan goigs and Schluckbildchen. Additional themes include the intersection of Catholic rituals with other faiths and spiritualities, as well as the history of Our Lady of Health across regions and centuries

Regulatory inspection and the changing legitimacy of health and safety

The regulation of conduct via law is a key mechanism through which broader social meanings are negotiated and expressed. The use of regulatory tools to bring about desired outcomes reflects existing social and political understandings about¬ institutional legitimacy, the meanings attached to regulation, and the values it seeks to advance. But these contextual understandings are not static, and their evolution poses challenges for regulators, particularly when they reflect political framing processes. This paper shows how inspection has been reshaped as a tool within the United Kingdom’s health and safety system by changes in the meanings attached to the concept of ‘risk-based regulation’. While rates of inspection have fallen dramatically in recent years, the nature and quality of inspection have also been fundamentally reshaped via an increasingly procedural and economically-rational ‘risk-based’ policy context. This has had consequences for the transformative and symbolic value of inspection as a tool of regulatory practice

Crisis, what crisis? Regulation and the academic orthodoxy

What can criminology or socio-legal studies tell us about the causes of the financial crisis – a failure of regulation, at the very least – or ways in which further such crises might be prevented, mitigated, responded to? The article begins by setting out the emergence and dimensions of the academic orthodoxy on regulation – a series of shared assumptions regarding feasible and desirable forms of regulation. Then it undertakes quantitative and qualitative content analysis of work on regulation and the crisis to assess the extent to which this orthodoxy has been reassessed in the light of events since 2007

Effects of intraoperative hypothermia on neuropsychological outcomes after intracranial aneurysm surgery

Objective Subarachnoid hemorrhage and surgical obliteration of ruptured intracranial aneurysms are frequently associated with neurological and neuropsychological abnormalities. We reported that intraoperative cooling did not improve neurological outcome in good-grade surgical subarachnoid hemorrhage patients, as assessed by the Glasgow Outcome Scale score or other neurological and functional measures (National Institutes of Health Stroke Scale, Rankin Disability Scale, Barthel Activities of Daily Living). We now report the results of neuropsychological testing in these patients. Methods A total of 1,001 patients who bled ≤14 days before surgery were randomly assigned to intraoperative hypothermia (t = 33°C) or normothermia (37°C). Outcome was assessed approximately 3 months after surgery. Patients underwent the Benton Visual Retention, Controlled Oral Word Association, Rey–Osterrieth Complex Figure, Grooved Pegboard, and the Trail Making tests. T -scores for each test were calculated from normative data. T -scores were averaged to calculate a Composite Score. A test result (or the Composite Score) was considered “impaired” if the T -score was two or more standard deviations below the norm. A Mini-Mental State Examination was also performed. Results Neurological outcome data were available in 1,000 patients. Sixty-one patients died. Of the 939 survivors, 873 completed 3 or more tests (exclusive of the Mini-Mental State Examination). Patients with poor neurological outcomes were less likely to complete testing; only 3.9% of Good Outcome (Glasgow Outcome Scale score = 1) patients were untested, compared with 38.6% of patients with Glasgow Outcome Scale scores of 3 and 4. There were no prerandomization demographic differences between the two treatment groups. For hypothermic patients, 16.8% were impaired from their Composite Score versus 20.0% of patients in the normothermic group ( p = 0.317). For patients in the hypothermic group, 54.5% were impaired on at least one test, compared with 55.5% of patients in the normothermic group ( p = 0.865). Similar results were seen in patients with baseline WFNS scores = I. Mini-Mental State Examination scores in the hypothermic and normothermic groups were 27.4 ± 3.8 and 26.8 ± 4.5, respectively. Interpretation This is the largest prospective evaluation of neuropsychological function after subarachnoid hemorrhage to date. Testing was completed in a high fraction of patients, demonstrating the feasibility of such testing in a large trial. However, the frequent inability to complete testing in poor-outcome patients suggests that testing may be best used to refine outcome assessments in good-grade patients. Many patients showed impairment on at least one test, with global impairment present in 17 to 20% of patients (18–21% of survivors). This was true even among the patients with the best preoperative condition (WFNS = 1). There was no difference in the incidence of impairment between hypothermic and normothermic groups. Ann Neurol 2006;60:518–527Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/55889/1/21018_ftp.pd

Educational interpreters for the deaf and hard of hearing: professional preparation, evaluation, and perceptions

The purpose of this study was to investigate the relationship between K-12 interpreters’ training in relation to the Model Standards (1993), their perceptions of preparation, and their evaluation scores on the Educational Interpreter Performance Assessment (EIPA) of current and recently working K-12 educational interpreters. A questionnaire was created and distributed to coordinators, chairs, and professors of interpreter training programs, national interpreting organizations, as well as to educational interpreting and American Sign Language interpreting groups on social media outlets. A total of 324 participants responded to the survey; 276 reported currently working in a K-12 educational setting, and 48 reported previous employment as an interpreter in a K-12 setting within the past 5 years. Results revealed that topic areas from the Model Standards (1993) are not being provided in formal interpreter training programs, EIPA scores continue to be below the minimum recommended skill level of 4.0, and participants feel unprepared to work as educational interpreters supporting deaf and hard-of-hearing students in K-12 settings

Aligning ancient and modern approaches to sustainable urban water management in China: Ningbo as a ‘Blue-Green City’ in the ‘Sponge City’ Campaign

Modern urban flood and water management emphasises holistic strategies that reduce flood risk while providing co- benefits to urban economies, societies and environments. The ‘Blue‐Green City’ concept provides a viable framework for putting this into practice. Ningbo, is a coastal city with high flood risk, whose history as a Chinese ‘water town’ demonstrates that approaches to water management implicit to the ‘Blue‐Green’ concept were practiced in ancient times, and lessons can be learned from these applications. Furthermore, recent launch of the ‘Sponge City’ campaign by China's National Government demonstrates the political will to implement sustainable flood and water management in ways consistent with the ‘Blue‐Green’ ideals. Selection of Ningbo for a pilot project presents the opportunity to integrate new ‘Sponge city’ approaches with ancient ‘Blue‐Green’ principles, within the contexts of both new urban development and retrofit. Reinventing traditional approaches to urban water management and governance offers the possibility of maintaining flood risk at acceptable levels without constraining urban growth in China and other countries experiencing rapid urban development

The sedimentation of an institution: changing governance in UK financial services

Post-print version. Final version published by Sage; available online at http://jmi.sagepub.com/The Financial Services Act (FSA) 1986 was the first comprehensive attempt to create a unified statutorily based system of regulation within the UK financial sector. It generated a framework of regulation that is in a continuous state of development and modification. In this paper we study the development of UK financial regulation between 1986 and 2011. We trace how competing theorizations and logics of regulation have led to the institutionalization of a meta-form of financial regulation. In doing so, we address the conundrum of conscious, strategic theorizations leading to cognitive taken-for-granted institutions by identifying four catalysts that contribute to institutionalization when concurring with theorization. These are: the evocation of political ideologies, the appropriation of scandals, the growing number of actors and the increasing organization of actors. Finally, we argue that sedimentation is the appropriate metaphor for the version of institutionalization occurring in this setting

High Target Homology Does Not Guarantee Inhibition: Aminothiazoles Emerge as Inhibitors of \u3ci\u3ePlasmodium falciparum\u3c/i\u3e

In this study, we identified three novel compound classes with potent activity against Plasmodium falciparum, the most dangerous human malarial parasite. Resistance of this pathogen to known drugs is increasing, and compounds with different modes of action are urgently needed. One promising drug target is the enzyme 1-deoxy-D-xylulose-5- phosphate synthase (DXPS) of the methylerythritol 4-phosphate (MEP) pathway for which we have previously identified three active compound classes against Mycobacterium tuberculosis. The close structural similarities of the active sites of the DXPS enzymes of P. falciparum and M. tuberculosis prompted investigation of their antiparasitic action, all classes display good cell-based activity. Through structure−activity relationship studies, we increased their antimalarial potency and two classes also show good metabolic stability and low toxicity against human liver cells. The most active compound 1 inhibits the growth of blood-stage P. falciparum with an IC50 of 600 nM. The results from three different methods for target validation of compound 1 suggest no engagement of DXPS. All inhibitor classes are active against chloroquine-resistant strains, confirming a new mode of action that has to be further investigated

Epithelial atypia in biopsies performed for microcalcifications. Practical considerations about 2,833 serially sectioned surgical biopsies with a long follow-up

This study analyzes the occurrence of epithelial atypia in 2,833 serially sectioned surgical breast biopsies (SB) performed for microcalcifications (median number of blocks per SB:26) and the occurrence of subsequent cancer after an initial diagnosis of epithelial atypia (median follow-up 160 months). Epithelial atypia (flat epithelial atypia, atypical ductal hyperplasia, and lobular neoplasia) were found in 971 SB, with and without a concomitant cancer in 301 (31%) and 670 (69%) SB, respectively. Thus, isolated epithelial atypia were found in 670 out of the 2,833 SB (23%). Concomitant cancers corresponded to ductal carcinomas in situ and micro-invasive (77%), invasive ductal carcinomas not otherwise specified (15%), invasive lobular carcinomas (4%), and tubular carcinomas (4%). Fifteen out of the 443 patients with isolated epithelial atypia developed a subsequent ipsilateral (n = 14) and contralateral (n = 1) invasive cancer. The high slide rating might explain the high percentages of epithelial atypia and concomitant cancers and the low percentage of subsequent cancer after a diagnosis of epithelial atypia as a single lesion. Epithelial atypia could be more a risk marker of concomitant than subsequent cancer