Wood mouse feeding effort and decision-making when encountering a restricted unknown food source

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Animals making foraging decisions must balance the energy gained, the time invested, and the influence of key environmental factors. In our work, we examined the effect of predation risk cues and experience on feeding efforts when a novel food resource was made available. To achieve this, we live-trapped wood mouse Apodemus sylvaticus in Monte de Valdelatas (Madrid), where 80 Sherman traps were set in four plots. Traps were subjected to two food-access difficulties in treatments consisting of three consecutive nights: open plastic bottles (easy) and closed bottles (difficult), both using corn as bait. To simulate predation risk, we set fox faeces in half of the traps in each plot. We also considered moonlight (medium/low) as an indirect predation risk cue. We analysed whether bottles had been bitten by mice and the gnawed area of each bottle was measured. Our results indicated that food access difficulty, experience, and predation risk determined mice feeding decisions and efforts. The ability of mice to adapt feeding effort when a new food source is available was demonstrated because a higher proportion of closed bottles exhibited bite marks and the gnawed area was bigger. Moreover, mouse experience was determinant in the use of this new resource since recaptured mice gnawed broader orifices in the bottles and the gnawed area increased each time an individual was recaptured. Additionally, direct predation risk cues prompted mice to bite the bottles whereas the effect of different moon phases varied among the food access treatments. This study provides direct evidence of formidable efficacy of wild mice to exploit a new nutrient resource while considering crucial environmental factors that shape the decision-making procedur

"Origo Constantini Imperatoris": comentario, notas y traducción

El objetivo de este artículo no es otro que presentar por primera vez una traducción al castellano de la "Origo Constantini Imperatoris", texto del s. IV dedicado a la vida y trayectoria política del emperador Constantino el Grande. Dicha traducción se presenta acompañada de un breve comentario histórico y literario con el que se pretende dar una visión global del estado actual de las investigaciones que esta obra ha generado.The aim of this paper is, basically, to present for the first time a Spanish translation of the "Origo Constantini Imperatoris". This is a text belonging to the 4th century, dedicated to Constantine the Great’s life and political course. The above mentioned translation is presented enclosed to a brief historic and literary commentary. It aims to give a general view of the current state of investigations that this work has generated.España. Ministerio de Educación y Ciencia AP20045943Aragón (Comunidad Autónoma) B037/200

FGF2, but not EGF, Induces multiciliated ependymal cells to dedifferentiate and adopt radial glial features in vitro

Multiciliated ependymal cells form an epithelium lining most of the ventricular cavities of vertebrates brain. Although considered postmitotic and completely differentiated, ependymal cells maintain some phenotypic characteristics of neural stem cells. Thereby, under specific conditions they behave as neural stem cells, developing radial glia characteristics, and undergoing asymmetric division. Our group is searching for factors that promote dedifferentiation of ependymal cells in vitro. We developed a simple method to obtain pure cultures of non-adherent multiciliated ependymal cells from adult rats. These cultures were used to investigate the effect of FGF2 on the differentiation state and the aggregation of ependymal cells. Thus, FGF2 treated ependymal cells lose cilia and hence mobility, and after 7 days they aggregate to form irregular spheres (diameter ≥ 20-30 μm). Such changes were not observed when EFG was used instead of FGF2. To assess the specificity of FGF2 action on cell aggregation, the FGF receptor inhibitor PD166866 and an anti-FGF2 neutralizing antibody were used. In both conditions the aggregative effect of FGF2 was abolished. No cell proliferation was observed during sphere formation, at least in such experimental conditions. Spheres were analyzed by immunocytochemistry using radial glia markers. They were positive for GFAP, vimentin, BLBP and GLAST. These data suggest that FGF2 promotes the identity loss in multiciliated ependymal cells in vitro, which are transformed into cells with radial glia features.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Alternative pathways to a sustainable future lead to contrasting biodiversity responses

Land-use change is currently the main driver of biodiversity loss. Projections of land-use change are often used to estimate potential impacts on biodiversity of future pathways of human development. However, such analyses frequently neglect that species can persist in human-modified habitats. Our aim was to estimate changes in biodiversity, considering affinities for multiple habitats, for three different land-use scenarios. Two scenarios focused on more sustainable trajectories of land-use change, based on either technological improvements (Pathway A) or societal changes (Pathway B), and the third reflected the historical or business-as-usual trends (Pathway 0). Using Portugal as a case study, we produced spatially-explicit projections of land-use change based on these pathways, and then we assessed the resulting changes in bird species richness and composition projected to occur by 2050 in each of the scenarios. By 2050, alpha and gamma diversity were projected to decrease, relative to 2010, in Pathway 0 and increase in Pathways A and B. However, different pathways favored different species groups, and presented strong regional differences. In the technological improvement pathway, loss of extensive agricultural areas led to an increase in both natural and extensive forest areas. In this pathway, forest species increase at the expense of farmland species, while in the societal change pathway the reverse occurs, as extensive agricultural areas were projected to increase. We show that while multiple positive pathways (A and B) for biodiversity can be envisioned, they will lead to differential impacts on biodiversity depending on the transformational changes in place and the regional socio-economic context. Our results suggest that considering compositional aspects of biodiversity can be critical in choosing the appropriate regional land-use policies

Temperature responsiveness of gilthead sea bream bone; an in vitro and in vivo approach

This study aimed to characterize the molecules involved in osteogenesis in seabream and establish using in vitro/in vivo approaches the responsiveness of selected key genes to temperature. The impact of a temperature drop from 23 to 13 degrees C was evaluated in juvenile fish thermally imprinted during embryogenesis. Both, in vitro/in vivo, Fib1a, appeared important in the first stages of bone formation, and Col1A1, ON and OP, in regulating matrix production and mineralization. OCN mRNA levels were up-regulated in the final larval stages when mineralization was more intense. Moreover, temperature-dependent differential gene expression was observed, with lower transcript levels in the larvae at 18 degrees C relative to those at 22 degrees C, suggesting bone formation was enhanced in the latter group. Results revealed that thermal imprinting affected the long-term regulation of osteogenesis. Specifically, juveniles under the low and low-to-high-temperature regimes had reduced levels of OCN when challenged, indicative of impaired bone development. In contrast, gene expression in fish from the high and high-to-low-temperature treatments was unchanged, suggesting imprinting may have a protective effect. Overall, the present study revealed that thermal imprinting modulates bone development in seabream larvae, and demonstrated the utility of the in vitro MSC culture as a reliable tool to investigate fish osteogenesis."Ministerio de Economia y Competitividad" (MINECO) [BES-2015-074654]; Portuguese Science Foundation (FCT) [SFRH/BPD/111512/2015, SFRH/BD/81625/2011]; MINECO, Spain [AGL2010-17324, AGL2014-57974-R]; "Generalitat de Catalunya" (XRAq); Generalitat de Catalunya [2014SGR-01371]; FCT, Portugal [CCMAR/Multi/04326/2013]; European Union [LIFECYCLE EU-FP7 222719]info:eu-repo/semantics/publishedVersio

Instruments de síntesi i integració : guia per a l'elaboració de l'anamnesi i l'informe

Per tal d'escollir un eix temàtic hem revisat base que sustenta el nostre treball i que detallem a continuació: (1)Creiem que el procés de canvi impulsat per l'IDES exigeix un canvi en les estratègies d'ensenyament aprenentatge, és per això que presentem una guia que pot servir com a un instrument de síntesi de diferents assignatures cursades al llarg de la diplomatura. A més afavoreix l'autoaprenentatge, autonomia i resolució de problemes. (2)El canvi d'estratègies comporta també una metodologia docent diferent que en el nostre cas combina presencialitat, virtualitat, treball autònom, treball en equip. La utilització de aquesta combinació de metodologies afavoreix també els diferents estils d'aprenentatge de l'alumnat, pesem que és important respectar les característiques individuals dels integrants del grup. Per totes aquestes raons creiem que l'eix temàtic que pot treball és el corresponent a: Estratègies d'aprenentatge: metodologies docents, autoaprenentatge, et

Delamination Study in Edge Trimming of Basalt Fiber Reinforced Plastics (BFRP)

[EN] Although there are many machining studies of carbon and glass fiber reinforced plastics, delamination and tool wear of basalt fiber reinforced plastics (BFRP) in edge trimming has not yet studied. This paper presents an end milling study of BFRP fabricated by resin transfer molding (RTM), to evaluate delamination types at the top layer of the machined edge with different cutting conditions (cutting speed, feed rate and depth of cut) and fiber volume fraction (40% and 60%). This work quantifies delamination types, using a parameter Sd/L, that evaluates the delamination area (Sd) and the length (L), taking into account tool position in the yarn and movement of yarns during RTM process, which show the random nature of delamination. Delamination was present in all materials with 60% of fiber volume. High values of tool wear did not permit to machine the material due to an excessive delamination. Type II delamination was the most usual delamination type and depth of cut has influence on this type of delamination.The authors gratefully acknowledge the funding by the Ministerio de Educacion y Ciencia of the Spanish government under grant DPI2013-44903-R-AR.Navarro-Mas, M.; García Manrique, JA.; Meseguer, MD.; Ordeig Fernández, IN.; Sánchez Galdón, AI. (2018). Delamination Study in Edge Trimming of Basalt Fiber Reinforced Plastics (BFRP). Materials. 11(8). doi:10.3390/ma1108141811