31 research outputs found
Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
- Author
- Ababneh Hazim S
- Abate Yohannes Habtegiorgis
- Abbafati Cristiana
- Abbasgholizadeh Rouzbeh
- Abbasian Mohammadreza
- Abbastabar Hedayat
- Abd Al Magied Abdallah H A
- Abd ElHafeez Samar
- Abd-Elsalam Sherief
- Abdelkader Atef
- Abdelmasseh Michael
- Abdi Parsa
- Abdollahi Mohammad
- Abdoun Meriem
- Abdullahi Auwal
- Abebe Mesfin
- Abiodun Olumide
- Aboagye Richard Gyan
- Abolhassani Hassan
- Abouzid Mohamed
- Aboye Girma Beressa
- Abreu Lucas Guimarães
- Absalan Abdorrahim
- Abualruz Hasan
- Abubakar Bilyaminu
- Abukhadijah Hana Jihad Jihad
- Addolorato Giovanni
- Adekanmbi Victor
- Adetunji Charles Oluwaseun
- Adetunji Juliana Bunmi
- Adeyeoluwa Temitayo Esther
- Adha Rishan
- Adhikary Ripon Kumar
- Adnani Qorinah Estiningtyas Sakilah
- Adzigbli Leticia Akua
- Afrashteh Fatemeh
- Afzal Muhammad Sohail
- Afzal Saira
- Agbozo Faith
- Agodi Antonella
- Agrawal Anurag
- Agyemang-Duah Williams
- Ahinkorah Bright Opoku
- Ahlstrom Austin J
- Ahmad Aqeel
- Ahmad Firdos
- Ahmad Muayyad M
- Ahmad Sajjad
- Ahmad Shahzaib
- Ahmed Anisuddin
- Ahmed Ayman
- Ahmed Haroon
- Ahmed Safoora
- Ahmed Syed Anees
- Akinosoglou Karolina
- Akkaif Mohammed Ahmed
- Akrami Ashley E
- Akter Ema
- Al Awaidy Salah
- Al Hasan Syed Mahfuz
- Al Mosa Amjad S
- Al Ta'ani Omar
- Al Zaabi Omar Ali Mohammed
- Al-Ajlouni Yazan
- Al-Aly Ziyad
- Al-amer Rasmieh Mustafa
- Al-Gheethi Adel Ali Saeed
- Al-Hanawi Mohammed Khaled
- Al-Ibraheem Akram
- Al-Mekhlafi Hesham M
- Al-Sabah Salman Khalifah
- Al-Tammemi Ala'a B.
- Al-Tawfiq Jaffar A
- Al-Wardat Mohammad Sami
- Al-Worafi Yaser Mohammed
- Al-Zyoud Walid
- Alahdab Fares
- Alajlani Muaaz M
- Alalalmeh Samer O
- Alam Khurshid
- Alam Noore
- Alam Tahiya
- Alam Zufishan
- Alanezi Fahad Mashhour
- Alanzi Turki M
- Albakri Almaza
- Aldhaleei Wafa A
- Aldridge Robert W
- Alemohammad Seyedeh Yasaman
- Alemu Yihun Mulugeta
- Ali Abid
- Ali Amjad
- Ali Iman
- Ali Mohammed Usman
- Ali Rafat
- Ali Syed Shujait Shujait
- Ali Victor Ekoche
- Ali Waad
- Alicandro Gianfranco
- Alif Sheikh Mohammad
- Aljunid Syed Mohamed
- Alla François
- Almazan Joseph Uy
- Alqutaibi Ahmed Yaseen
- Alrawashdeh Ahmad
- Alrousan Sahel Majed
- Alsabri Mohammed A
- Altaany Zaid
- Altirkawi Khalid A
- Aluh Deborah Oyine
- Alvis-Guzman Nelson
- Aly Hany
- Alyahya Mohammad Sharif
- Alzoubi Karem H
- Amani Reza
- Ameyaw Edward Kwabena
- Amin Tarek Tawfik
- Amindarolzarbi Alireza
- Amiri Sohrab
- Amirzade-Iranaq Mohammad Hosein
- Amu Hubert
- Amugsi Dickson A
- Ancuceanu Robert
- Anderlini Deanna
- Anderson David B
- Andrade Pedro Prata
- Andrei Catalina Liliana
- Andrei Tudorel
- Andrews Erick Adrian
- Anil Abhishek
- Anil Sneha
- Anoushiravani Amir
- Antony Catherine M
- Antriyandarti Ernoiz
- Anuoluwa Boluwatife Stephen
- Anvari Saeid
- Anyasodor Anayochukwu Edward
- Appiah Francis
- Aquilano Michele
- Arab Juan Pablo
- Arabloo Jalal
- Arafa Elshaimaa A
- Arafat Mosab
- Aravkin Aleksandr Y
- Ardekani Ali
- Areda Demelash
- Aregawi Brhane Berhe
- Aremu Abdulfatai
- Ariffin Hany
- Arkew Mesay
- Armani Keivan
- Artamonov Anton A
- Arumugam Ashokan
- Asghari-Jafarabadi Mohammad
- Ashbaugh Charlie
- Astell-Burt Thomas
- Athari Seyyed Shamsadin
- Atorkey Prince
- Atout Maha Moh'd Wahbi
- Aujayeb Avinash
- Ausloos Marcel
- Awad Hamzeh
- Awotidebe Adedapo Wasiu
- Ayatollahi Haleh
- Ayuso-Mateos Jose L
- Azadnajafabad Sina
- Azeez Fahad Khan
- Azevedo Rui M S
- Badar Muhammad
- Baghdadi Soroush
- Bagheri Mahboube
- Bagheri Nasser
- Bai Ruhai
- Baker Jennifer L
- Bako Abdulaziz T
- Balakrishnan Senthilkumar
- Balcha Wondu Feyisa
- Baltatu Ovidiu Constantin
- Barchitta Martina
- Bardideh Erfan
- Barker-Collo Suzanne Lyn
- Barqawi Hiba Jawdat
- Barteit Sandra
- Basiru Afisu
- Basso João Diogo
- Bastan Mohammad-Mahdi
- Basu Sanjay
- Bauckneht Matteo
- Baune Bernhard T
- Bayati Mohsen
- Bayileyegn Nebiyou Simegnew
- Bärnighausen Till Winfried
- Behnoush Amir Hossein
- Behzadi Payam
- Beiranvand Maryam
- Bello Olorunjuwon Omolaja
- Belo Luis
- Beloukas Apostolos
- Bemanalizadeh Maryam
- Bensenor Isabela M
- Benzian Habib
- Beran Azizullah
- Berezvai Zombor
- Bernstein Robert S
- Bettencourt Paulo J G
- Beyene Kebede A
- Beyene Melak Gedamu
- Bhagat Devidas S
- Bhagavathula Akshaya Srikanth
- Bhala Neeraj
- Bhandari Dinesh
- Bharadwaj Ravi
- Bhardwaj Nikha
- Bhardwaj Pankaj
- Bhargava Ashish
- Bhaskar Sonu
- Bhat Vivek
- Bhattacharjee Natalia V
- Bhatti Gurjit Kaur
- Bhatti Jasvinder Singh
- Bhatti Manpreet S
- Bhuiyan Mohiuddin Ahmed
- Bisignano Catherine
- Biswas Bijit
- Bjørge Tone
- Bodolica Virginia
- Bodunrin Aadam Olalekan
- Bonakdar Hashemi Milad
- Bora Basara Berrak
- Borhany Hamed
- Bosoka Samuel Adolf
- Botero Carvajal Alejandro
- Bouaoud Souad
- Boufous Soufiane
- Boxe Christopher
- Boyko Edward J
- Brady Oliver J
- Braithwaite Dejana
- Brauer Michael
- Brazo-Sayavera Javier
- Brenner Hermann
- Brown Colin Stewart
- Browne Annie J
- Brugha Traolach
- Bryazka Dana
- Bulamu Norma B
- Buonsenso Danilo
- Burkart Katrin
- Burns Richard A
- Busse Reinhard
- Bustanji Yasser
- Butt Zahid A
- Caetano dos Santos Florentino Luciano
- Calina Daniela
- Campos Luciana Aparecida
- Cao Shujin
- Capodici Angelo
- Carreras Giulia
- Carugno Andrea
- Carvalho Márcia
- Castaldelli-Maia Joao Mauricio
- Castelpietra Giulio
- Cattaruzza Maria Sofia
- Caye Arthur
- Cárdenas Rosario
- Cegolon Luca
- Cembranel Francieli
- Cenko Edina
- Cerin Ester
- Chadban Steven J
- Chadwick Joshua
- Chakraborty Chiranjib
- Chakraborty Sandip
- Chalek Julian
- Chan Jeffrey Shi Kai
- Chandika Rama Mohan
- Chandy Sara
- Charan Jaykaran
- Chaudhary Anis Ahmad
- Chaurasia Akhilanand
- Chen An-Tian
- Chen Haowei
- Chen Meng Xuan
- Chen Simiao
- Cherbuin Nicolas
- Chi Gerald
- Chichagi Fatemeh
- Chimed-Ochir Odgerel
- Chimoriya Ritesh
- Ching Patrick R
- Chirinos-Caceres Jesus Lorenzo
- Chitheer Abdulaal
- Cho Daniel Youngwhan
- Cho William C S
- Choi Dong-Woo
- Chong Bryan
- Chong Chean Lin
- Chopra Hitesh
- Chu Dinh-Toi
- Chung Eric
- Chutiyami Muhammad
- Clayton Justin T
- Cogen Rebecca M
- Cohen Aaron J
- Columbus Alyssa
- Comfort Haley
- Conde Joao
- Connolly Jon T
- Cooper Ezra E K
- Cortese Samuele
- Cruz-Martins Natália
- Çakmak Barsbay Mehtap
- D'Oria Mario
- da Silva Alanna Gomes
- Dadras Omid
- Dai Xiaochen
- Dai Zhaoli
- Dalton Bronte E
- Damiani Giovanni
- Dandona Lalit
- Dandona Rakhi
- Das Jai K
- Das Saswati
- Das Subasish
- Dash Nihar Ranjan
- Davletov Kairat
- De la Hoz Fernando Pio
- De Leo Diego
- Debopadhaya Shayom
- Delgado-Enciso Ivan
- Denova-Gutiérrez Edgar
- Dervenis Nikolaos
- Desai Hardik Dineshbhai
- Devanbu Vinoth Gnana Chellaiyan
- Dewan Syed Masudur Rahman
- Dhama Kuldeep
- Dhane Amol S
- Dhingra Sameer
- Dias da Silva Diana
- Diaz Daniel
- Diaz Luis Antonio
- Diaz Michael J
- Dima Adriana
- Ding Delaney D
- do Prado Camila Bruneli
- Do Thao Huynh Phuong
- Dodangeh Masoud
- Dodangeh Milad
- Doegah Phidelia Theresa
- Dohare Sushil
- Dong Wanyue
- Doshi Rajkumar
- Dowou Robert Kokou
- Dsouza Haneil Larson
- Dsouza Viola
- Dube John
- Dumith Samuel C
- Duncan Bruce B
- Duraes Andre Rodrigues
- Duraisamy Senbagam
- Durojaiye Oyewole Christopher
- Dushpanova Anar
- Dutta Sulagna
- Dzianach Paulina Agnieszka
- Dziedzic Arkadiusz Marian
- Eboreime Ejemai
- Ebrahimi Kalan Mohammad
- Ebrahimi Alireza
- Edinur Hisham Atan
- Efendi Ferry
- Eikemo Terje Andreas
- Eini Ebrahim
- Ekundayo Temitope Cyrus
- El Arab Rabie Adel
- El Sayed Iman
- Elamin Osman
- Elemam Noha Mousaad
- ElGohary Ghada Metwally Tawfik
- Elhadi Muhammed
- Elmeligy Omar Abdelsadek Abdou
- Elmoselhi Adel B
- Elshaer Mohammed
- Elsohaby Ibrahim
- Eltahir Mohd. Elmagzoub
- Emeto Theophilus I
- Eshrati Babak
- Eslami Majid
- Esmaeili Zahra
- Fabin Natalia
- Fagbamigbe Adeniyi Francis
- Fagbule Omotayo Francis
- Falzone Luca
- Fareed Mohammad
- Farinha Carla Sofia e Sá
- Faris MoezAlIslam Ezzat Mahmoud
- Faro Andre
- Fasihi Kiana
- Fatehizadeh Ali
- Fauk Nelsensius Klau
- Fazylov Timur
- Feigin Valery L
- Fekadu Ginenus
- Feng Xiaoqi
- Fereshtehnejad Seyed-Mohammad
- Ferrara Pietro
- Ferreira Nuno
- Firew Belete Sewasew
- Fischer Florian
- Fitriana Ida
- Flavel Joanne
- Flor Luisa S
- Folayan Morenike Oluwatoyin
- Foley Kristen Marie
- Fonzo Marco
- Force Lisa M
- Foschi Matteo
- Freitas Alberto
- Fridayani Ni Kadek Yuni
- Fukutaki Kai Glenn
- Furtado João M
- Fux Blima
- Gaal Peter Andras
- Gadanya Muktar A
- Gallus Silvano
- Ganesan Balasankar
- Ganiyani Mohammad Arfat
- Gautam Rupesh K
- Gebi Tilaye Gebru
- Gebregergis Miglas W
- Gebrehiwot Mesfin
- Getacher Lemma
- Getahun Genanew K A
- Gething Peter W
- Ghadimi Delaram J
- Ghadirian Fataneh
- Ghafarian Sadegh
- Ghailan Khalid Yaser
- Ghasemi MohammadReza
- Ghasempour Dabaghi Ghazal
- Ghazy Ramy Mohamed
- Ghoba Sama
- Gholami Ehsan
- Gholamrezanezhad Ali
- Gholizadeh Nasim
- Ghorbani Vajargah Pooyan
- Ghorbani Mahsa
- Ghotbi Elena
- Gil Artyom Urievich
- Gill Tiffany K
- Girmay Alem
- Glasbey James C
- Glushkova Ekaterina Vladimirovna
- Gnedovskaya Elena V
- Goldust Mohamad
- Goleij Pouya
- Golinelli Davide
- Gopalani Sameer Vali
- Goulart Alessandra C
- Gouravani Mahdi
- Goyal Anmol
- Göbölös Laszlo
- Grivna Michal
- Grosso Giuseppe
- Guarducci Giovanni
- Gubari Mohammed Ibrahim Mohialdeen
- Guicciardi Stefano
- Guimarães Rafael Alves
- Gulati Snigdha
- Gulisashvili David
- Gunawardane Damitha Asanga
- Guo Cui
- Gupta Anish Kumar
- Gupta Rahul
- Gupta Rajeev
- Gupta Renu
- Gupta Sapna
- Gupta Vijai Kumar
- Haakenstad Annie
- Hadi Najah R
- Haep Nils
- Hafiz Abdul
- Haghmorad Dariush
- Haile Demewoz
- Haj-Mirzaian Arvin
- Hajj Ali Adel
- Hajj Ali Ali
- Halboub Esam S
- Haller Sebastian
- Halwani Rabih
- Hamagharib Abdullah Kanaan
- Hamdy Nadia M
- Hamoudi Rifat
- Hanifi Nasrin
- Hankey Graeme J
- Haq Zaim Anan
- Haque Md Rabiul
- Harapan Harapan
- Hargono Arief
- Haro Josep Maria
- Hasaballah Ahmed I
- Hasan S. M. Mahmudul
- Hasanian Mohammad
- Hasnain Md Saquib
- Hassan Amr
- Haubold Johannes
- Hay Simon I
- Hebert Jeffrey J
- Hegazi Omar E
- Heidari Mohammad
- Hemmati Mehdi
- Henson Claire A
- Herrera-Serna Brenda Yuliana
- Herteliu Claudiu
- Heydari Majid
- Hezam Kamal
- Hidayana Irma
- Hiraike Yuta
- Hoan Nguyen Quoc
- Holla Ramesh
- Hoogar Praveen
- Horita Nobuyuki
- Hossain Md Mahbub
- Hosseinzadeh Hassan
- Hosseinzadeh Mehdi
- Hostiuc Mihaela
- Hostiuc Sorin
- Hu Chengxi
- Huang Junjie
- Hultström Michael
- Hundie Tsegaye Gebreyes
- Hunt Aliza J
- Hushmandi Kiavash
- Hussain Javid
- Hussain M. Azhar
- Hussein Nawfal R
- Huynh Hong-Han
- Hwang Bing-Fang
- Ibitoye Segun Emmanuel
- Iftikhar Pulwasha Maria
- Ikiroma Adalia I
- Ikwegbue Paul Chukwudi
- Ilic Irena M
- Ilic Milena D
- Immurana Mustapha
- Isa Mustafa Alhaji
- Islam Md. Rabiul
- Islam Sheikh Mohammed Shariful
- Ismail Faisal
- Ismail Nahlah Elkudssiah
- Isola Gaetano
- Iwagami Masao
- Iyamu Ihoghosa Osamuyi
- Jacob Louis
- Jacobsen Kathryn H
- Jafarinia Morteza
- Jahankhani Kasra
- Jahanmehr Nader
- Jain Nityanand
- Jairoun Ammar Abdulrahman
- Jakhmola Mani Dr Ruchi
- Jamil Safayet
- Jamora Roland Dominic G
- Jatau Abubakar Ibrahim
- Javadov Sabzali
- Javaheri Tahereh
- Jayaram Shubha
- Jee Sun Ha
- Jeganathan Jayakumar
- Jiang Heng
- Jokar Mohammad
- Jonas Jost B
- Joseph Nitin
- Joshua Charity Ehimwenma
- Jürisson Mikk
- K Vaishali
- Kabir Ali
- Kabir Zubair
- Kadashetti Vidya
- Kalankesh Laleh R
- Kalra Sanjay
- Kamath Ashwin
- Kamath Rajesh
- Kamireddy Arun
- Kanaan Mona
- Kanchan Tanuj
- Kanmiki Edmund Wedam
- Kanmodi Kehinde Kazeem
- Kansal Sushil Kumar
- Karim Asima
- Karkhah Samad
- Kashoo Faizan Zaffar
- Kasraei Hengameh
- Kassel Molly B
- Katikireddi Srinivasa Vittal
- Kauppila Joonas H
- Kaur Harkiran
- Kayode Gbenga A
- Kazemi Foad
- Kazemian Sina
- Kebede Fassikaw
- Kendal Evie Shoshannah
- Kesse-Guyot Emmanuelle
- Khademvatan Shahram
- Khajuria Himanshu
- Khalaji Amirmohammad
- Khalid Asaad
- Khalid Nauman
- Khalilian Alireza
- Khamesipour Faham
- Khan Fayaz
- Khan Mohammad Jobair
- Khan Moien AB
- Khanmohammadi Shaghayegh
- Khatab Khaled
- Khatatbeh Haitham
- Khatatbeh Moawiah Mohammad
- Khatib Mahalaqua Nazli
- Khayat Kashani Hamid Reza
- Kheirallah Khalid A
- Khokhar Manoj
- Khormali Moein
- Khorrami Zahra
- Khosla Atulya Aman
- Khosravi Majid
- Khosrowjerdi Mahmood
- Khubchandani Jagdish
- Kifle Zemene Demelash
- Kim Grace
- Kim Julie Sojin
- Kim Min Seo
- Kim Yun Jin
- Kimokoti Ruth W
- Kisa Adnan
- Kisa Sezer
- Knibbs Luke D
- Knudsen Ann Kristin Skrindo
- Kochhar Sonali
- Kolahi Ali-Asghar
- Kompani Farzad
- Koren Gerbrand
- Korzh Oleksii
- Krishan Kewal
- Krishna Varun
- Krishnamoorthy Vijay
- Kucuk Bicer Burcu
- Kuddus Md Abdul
- Kuddus Mohammed
- Kuitunen Ilari
- Kujan Omar
- Kulimbet Mukhtar
- Kulkarni Vishnutheertha
- Kumar G Anil
- Kumar Harish
- Kumar Nithin
- Kumar Rakesh
- Kumar Vijay
- Kundu Amartya
- Kusuma Dian
- Kyei-Arthur Frank
- Kytö Ville
- Kyu Hmwe Hmwe
- La Vecchia Carlo
- Lacey Ben
- Ladan Muhammad Awwal
- Laflamme Lucie
- Lahariya Chandrakant
- Lai Daphne Teck Ching
- Lalloo Ratilal
- Lallukka Tea
- Lan Qing
- Lan Tuo
- Landires Iván
- Lanfranchi Francesco
- Langguth Berthold
- Lansingh Van Charles
- Laplante-Lévesque Ariane
- Larijani Bagher
- Larsson Anders O
- Lasrado Savita
- Lauriola Paolo
- Lawlor Hilary R
- Lám Judit
- Le Huu-Hoai
- Le Long Khanh Dao
- Le Nhi Huu Hanh
- Le Thao Thi Thu
- Le Trang Diep Thanh
- Leasher Janet L
- Lee Doo Woong
- Lee Munjae
- Lee Paul H
- Lee Sang-woong
- Lee Seung Won
- Lee Shaun Wen Huey
- Lee Yo Han
- Leigh James
- Leong Elvynna
- Li Ming-Chieh
- Libra Massimo
- Ligade Virendra S
- Lim Lee-Ling
- Lim Stephen S
- Limenh Liknaw Workie
- Lindholm Daniel
- Lindstedt Paulina A
- Listl Stefan
- Liu Gang
- Liu Shiwei
- Liu Shuke
- Liu Xiaofeng
- Liu Xuefeng
- Llanaj Erand
- Loreche Arianna Maever
- Lotufo Paulo A
- Lozano Rafael
- López-Bueno Rubén
- López-Gil José Francisco
- Lubinda Jailos
- Lucchetti Giancarlo
- Luo Lisha
- Lusk Jay B
- Lv Lei
- M Amin Hawraz Ibrahim
- Ma Zheng Feei
- Maass Kelsey Lynn
- Machairas Nikolaos
- Machoy Monika
- Madureira-Carvalho Áurea M
- Magdy Abd El Razek Hassan
- Maghazachi Azzam A
- Mahadeshwara Prasad D. R.
- Mahalleh Mehrdad
- Mahasha Phetole Walter
- Mahmoud Mansour Adam
- Mahmoudi Elham
- Mahmoudvand Golnaz
- Makama Maureen
- Malakan Rad Elaheh
- Malhotra Kashish
- Malik Ahmad Azam
- Malta Deborah Carvalho
- Manla Yosef
- Mansour Ali
- Mansouri Mohammad Hadi
- Mansouri Pejman
- Mansouri Vahid
- Mansourian Marjan
- Mansournia Mohammad Ali
- Marasini Bishnu P
- Marateb Hamid Reza
- Maravilla Joemer C
- Mardi Parham
- Marjani Abdoljalal
- Markazi Moghadam Hamed
- Marrugo Arnedo Carlos Alberto
- Martinez Gabriel
- Martinez-Piedra Ramon
- Martins-Melo Francisco Rogerlândio
- Martorell Miquel
- Marx Wolfgang
- Marzo Roy Rillera
- Masoudi Sahar
- Mathangasinghe Yasith
- Mathioudakis Alexander G
- Mathur Medha
- Mathur Navgeet
- Mathur Neeta
- Matozinhos Fernanda Penido
- Mattumpuram Jishanth
- Maude Richard James
- Maugeri Andrea
- Mayeli Mahsa
- Mazidi Mohsen
- Mazzotti Antonio
- McGrath John J
- McKee Martin
- McKowen Anna Laura W
- McPhail Michael A
- McPhail Steven M
- Mehmood Asim
- Mehrabani-Zeinabad Kamran
- Mehravar Sepideh
- Mekene Meto Tesfahun
- Melese Endalkachew Belayneh
- Mendez-Lopez Max Alberto Mendez
- Mendoza Walter
- Menezes Ritesh G
- Mensah George A
- Mensah Laverne G
- Mentis Alexios-Fotios A
- Meo Sultan Ayoub
- Meretoja Atte
- Meretoja Tuomo J
- Mersha Abera M
- Mestrovic Tomislav
- Mettananda Kukulege Chamila Dinushi
- Mettananda Sachith
- Mhlanga Adquate
- Mhlanga Laurette
- Miazgowski Tomasz
- Michalek Irmina Maria
- Micheletti Gomide Nogueira de Sá Ana Carolina
- Miller Ted R
- Minh Le Huu Nhat
- Mirahmadi Alireza
- Mirijello Antonio
- Mirrakhimov Erkin M
- Mirzaei Roya
- Mitchell Philip B
- Mittal Chaitanya
- Moberg Madeline E
- Moghadam Fard Atousa
- Mohajelin Seyedehfatemeh
- Mohamadkhani Ashraf
- Mohamed Ahmed Ismail
- Mohamed Jama
- Mohamed Mouhand F H
- Mohamed Nouh Saad
- Mohammad Ameen Mosa
- Mohammadi Soheil
- Mohammed Hussen
- Mohammed Mustapha
- Mohammed Shafiu
- Mokdad Ali H
- Molokhia Mariam
- Momani Shaher Mohammad
- Momtazmanesh Sara
- Monasta Lorenzo
- Mondello Stefania
- Moni Mohammad Ali
- Montazeri Fateme
- Moodi Ghalibaf AmirAli
- Moradi Maryam
- Moradi Yousef
- Moraga Paula
- Morawska Lidia
- Moreira Rafael Silveira
- Morovatdar Negar
- Morrison Shane Douglas
- Mosapour Abbas
- Mosser Jonathan F
- Mossialos Elias
- Motappa Rohith
- Mougin Vincent
- Mousavi Parsa
- Mrejen Matías
- Mubarik Sumaira
- Mueller Ulrich Otto
- Mulita Francesk
- Munjal Kavita
- Murillo-Zamora Efrén
- Murray Christopher J L
- Musallam Khaled M
- Musina Ana-Maria
- Mustafa Ghulam
- Myung Woojae
- Nafei Ayoub
- Nagarajan Ahamarshan Jayaraman
- Naghavi Pirouz
- Naik Ganesh R
- Naik Gurudatta
- Nainu Firzan
- Najdaghi Soroush
- Nakhostin Ansari Noureddin
- Nangia Vinay
- Narasimha Swamy Sreenivas
- Nargus Shumaila
- Narimani Davani Delaram
- Nascimento Bruno Ramos
- Nascimento Gustavo G
- Naser Abdallah Y
- Nashwan Abdulqadir J
- Natto Zuhair S
- Nauman Javaid
- Navaratna Samidi N K
- Naveed Muhammad
- Nawsherwan null
- Nayak Biswa Prakash
- Nayak Vinod C
- Negash Hadush
- Negoi Ionut
- Negoi Ruxandra Irina
- Nejadghaderi Seyed Aria
- Nejjari Chakib
- Nematollahi Soroush
- Netsere Henok Biresaw
- Ng Marie
- Nguefack-Tsague Georges
- Ngunjiri Josephine W
- Nguyen Tran Minh Duc
- Nguyen Anh Hoang
- Nguyen Dang H
- Nguyen Duc Hoang
- Nguyen Hau Thi Hien
- Nguyen Nhan
- Nguyen Nhien Ngoc Y
- Nguyen Phat Tuan
- Nguyen QuynhAnh P
- Nguyen Van Thanh
- Niazi Robina Khan
- Nigatu Yeshambel T
- Niknam Mahdieh
- Nikoobar Ali
- Nikpoor Amin Reza
- Nikravangolsefid Nasrin
- Noman Efaq Ali
- Nomura Shuhei
- Noor Syed Toukir Ahmed
- Noroozi Nafise
- Nouri Mehran
- Nozari Majid
- Nri-Ezedi Chisom Adaobi
- Ntaios George
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- Wojewodzic Marcin W
- Woldeyes Dawit Habte
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- Wolfe Charles D A
- Wu Chenkai
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- Wulf Hanson Sarah
- Xiao Hong
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- Yezli Saber
- Yigzaw Zeamanuel Anteneh
- Yiğit Arzu
- Yiğit Vahit
- Yin Dehui
- Yip Paul
- Yonemoto Naohiro
- You Yuyi
- Younis Mustafa Z
- Yu Chuanhua
- Yu Elaine A
- Yu Yong
- Yuan Chun-Wei
- Yusuf Hadiza
- Zafar Uzma
- Zafari Nima
- Zahid Mondal Hasan
- Zakham Fathiah
- Zaki Nazar
- Zerfu Taddese Alemu
- Zhang Haijun
- Zhang Jingya
- Zhang Liqun
- Zhang Yunquan
- Zhang Zhiqiang
- Zhao Xiu-Ju George
- Zhao Yang
- Zhao Zhongyi
- Zhong Chenwen
- Zhou Bolun
- Zhou Juexiao
- Zhou Shangcheng
- Zhu Bin
- Zhumagaliuly Abzal
- Zielińska Magdalena
- Zoghi Ghazal
- Zumla Alimuddin
- Zyoud Sa'ed H
- Zyoud Samer H
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Future trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and prioritisation. We have expanded and improved upon previous forecasts produced as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) and provide a reference forecast (the most likely future), and alternative scenarios assessing disease burden trajectories if selected sets of risk factors were eliminated from current levels by 2050. Methods: Using forecasts of major drivers of health such as the Socio-demographic Index (SDI; a composite measure of lag-distributed income per capita, mean years of education, and total fertility under 25 years of age) and the full set of risk factor exposures captured by GBD, we provide cause-specific forecasts of mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) by age and sex from 2022 to 2050 for 204 countries and territories, 21 GBD regions, seven super-regions, and the world. All analyses were done at the cause-specific level so that only risk factors deemed causal by the GBD comparative risk assessment influenced future trajectories of mortality for each disease. Cause-specific mortality was modelled using mixed-effects models with SDI and time as the main covariates, and the combined impact of causal risk factors as an offset in the model. At the all-cause mortality level, we captured unexplained variation by modelling residuals with an autoregressive integrated moving average model with drift attenuation. These all-cause forecasts constrained the cause-specific forecasts at successively deeper levels of the GBD cause hierarchy using cascading mortality models, thus ensuring a robust estimate of cause-specific mortality. For non-fatal measures (eg, low back pain), incidence and prevalence were forecasted from mixed-effects models with SDI as the main covariate, and YLDs were computed from the resulting prevalence forecasts and average disability weights from GBD. Alternative future scenarios were constructed by replacing appropriate reference trajectories for risk factors with hypothetical trajectories of gradual elimination of risk factor exposure from current levels to 2050. The scenarios were constructed from various sets of risk factors: environmental risks (Safer Environment scenario), risks associated with communicable, maternal, neonatal, and nutritional diseases (CMNNs; Improved Childhood Nutrition and Vaccination scenario), risks associated with major non-communicable diseases (NCDs; Improved Behavioural and Metabolic Risks scenario), and the combined effects of these three scenarios. Using the Shared Socioeconomic Pathways climate scenarios SSP2-4.5 as reference and SSP1-1.9 as an optimistic alternative in the Safer Environment scenario, we accounted for climate change impact on health by using the most recent Intergovernmental Panel on Climate Change temperature forecasts and published trajectories of ambient air pollution for the same two scenarios. Life expectancy and healthy life expectancy were computed using standard methods. The forecasting framework includes computing the age-sex-specific future population for each location and separately for each scenario. 95% uncertainty intervals (UIs) for each individual future estimate were derived from the 2·5th and 97·5th percentiles of distributions generated from propagating 500 draws through the multistage computational pipeline. Findings: In the reference scenario forecast, global and super-regional life expectancy increased from 2022 to 2050, but improvement was at a slower pace than in the three decades preceding the COVID-19 pandemic (beginning in 2020). Gains in future life expectancy were forecasted to be greatest in super-regions with comparatively low life expectancies (such as sub-Saharan Africa) compared with super-regions with higher life expectancies (such as the high-income super-region), leading to a trend towards convergence in life expectancy across locations between now and 2050. At the super-region level, forecasted healthy life expectancy patterns were similar to those of life expectancies. Forecasts for the reference scenario found that health will improve in the coming decades, with all-cause age-standardised DALY rates decreasing in every GBD super-region. The total DALY burden measured in counts, however, will increase in every super-region, largely a function of population ageing and growth. We also forecasted that both DALY counts and age-standardised DALY rates will continue to shift from CMNNs to NCDs, with the most pronounced shifts occurring in sub-Saharan Africa (60·1% [95% UI 56·8–63·1] of DALYs were from CMNNs in 2022 compared with 35·8% [31·0–45·0] in 2050) and south Asia (31·7% [29·2–34·1] to 15·5% [13·7–17·5]). This shift is reflected in the leading global causes of DALYs, with the top four causes in 2050 being ischaemic heart disease, stroke, diabetes, and chronic obstructive pulmonary disease, compared with 2022, with ischaemic heart disease, neonatal disorders, stroke, and lower respiratory infections at the top. The global proportion of DALYs due to YLDs likewise increased from 33·8% (27·4–40·3) to 41·1% (33·9–48·1) from 2022 to 2050, demonstrating an important shift in overall disease burden towards morbidity and away from premature death. The largest shift of this kind was forecasted for sub-Saharan Africa, from 20·1% (15·6–25·3) of DALYs due to YLDs in 2022 to 35·6% (26·5–43·0) in 2050. In the assessment of alternative future scenarios, the combined effects of the scenarios (Safer Environment, Improved Childhood Nutrition and Vaccination, and Improved Behavioural and Metabolic Risks scenarios) demonstrated an important decrease in the global burden of DALYs in 2050 of 15·4% (13·5–17·5) compared with the reference scenario, with decreases across super-regions ranging from 10·4% (9·7–11·3) in the high-income super-region to 23·9% (20·7–27·3) in north Africa and the Middle East. The Safer Environment scenario had its largest decrease in sub-Saharan Africa (5·2% [3·5–6·8]), the Improved Behavioural and Metabolic Risks scenario in north Africa and the Middle East (23·2% [20·2–26·5]), and the Improved Nutrition and Vaccination scenario in sub-Saharan Africa (2·0% [–0·6 to 3·6]). Interpretation: Globally, life expectancy and age-standardised disease burden were forecasted to improve between 2022 and 2050, with the majority of the burden continuing to shift from CMNNs to NCDs. That said, continued progress on reducing the CMNN disease burden will be dependent on maintaining investment in and policy emphasis on CMNN disease prevention and treatment. Mostly due to growth and ageing of populations, the number of deaths and DALYs due to all causes combined will generally increase. By constructing alternative future scenarios wherein certain risk exposures are eliminated by 2050, we have shown that opportunities exist to substantially improve health outcomes in the future through concerted efforts to prevent exposure to well established risk factors and to expand access to key health interventions
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- Achilleos Eleni
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- Adamuz Jordi
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- Adekola Oyebola
- Ademokun Jane
- Adenekan Anthony
- Adib Nik Azman Nik
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- Aganon Ferdinand
- Agarwal Sonika
- Aguirre Joaquin
- Aguirre Lydia Gallego
- Aguirre-Bermeo Hernan
- Ahmad Fatima Kasem El
- Ahmad Meraj
- Ahmed Hazem
- Ahn Jong-Joon
- Ahtiala Maarit
- Akbas Turkay
- Akdağ Devrim
- Akker Mustafa
- Akselsen Gro Ringstad
- Al-Alawi Maram Milud Said
- Alabuzidi Aya
- Alampi Daniela
- Albaiceta Guillermo Muñiz
- Albert Patricia
- Albrecht Lea
- Albrett Jonathan
- Alexandropoulou Paraskevi
- Alexandrou Anna
- Ali Ashwaq
- Ali Mohd Nazri
- Alias Anita
- Alkhumsi Soad Imhmed R.
- Allaert Silvie
- Allison Nicola
- Almekhlafi Ghaleb
- Alonso Helena Fernandez
- Alsheikhly Ahmed Subhy
- Alshrif Abdualhamid I
- Alvarenga Gloria
- Alvarez Diana
- Alvarez Gonzalo Martín
- Alvarez Gustavo Andres
- Alvarez Jorge Duerto
- Alvarez Josep Trenado
- Alvarez Raquel Garcia
- Alves Paulo
- Andersen Marit Hildegunn
- Andersen Yvonne
- Andresen Hanne
- Anisoglou Souzana
- Antonio Maria Gracia San
- Antunes Nelson
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- Aperocho Cristal April Jane
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- Arcas María Luisa Bravo
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- Avramopoulou Lamprini
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- Uba Stella
- Uccelli Francesco
- Udiljak Nikolina
- Ugwu Innocent
- Umek Nejc
- Undar Hasan Nabi
- Vakalos Aristeidis
- Valerio Idália
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- Villanueva Ximena
- Villegas Paula
- Viveiros Abel
- Vizcaychipi Marcela
- Vlaovic Janko
- Vochin Ana
- Volta Carlo Alberto
- von der Osten Ingrid
- Von Der Osten Ingrid
- von Lewinski Dirk
- Vosylius Saulius
- Vuković Anita
- Vullum Sylvi
- Vymazal Tamas
- Vymazal Tomas
- Wahab Sherliza
- Wahlbom Ewa
- Waibel Hansjoerg
- Wallin Ewa
- Walsh Amy
- Wan Jianhong
- Wan Yan
- Wang Damei
- Wang Fanglan
- Wang GuoXian
- Wang Hai Yun
- Wang Haiyan
- Wang Jing
- Wang Kefang
- Wang LingLing
- Wang RuiXia
- Wang Shuhui
- Wang Shuo
- Wang Wei
- Wang Wenmei
- Wang Xiaomin
- Wang Yan
- Wang Ying
- Wang Yingli
- Wang Yuping
- Wang Yuxia
- Watts Stacey
- Waweru-Siika Wangari
- Wei Dongfang
- Wei Wei
- Wei Xiyan
- Wei Ying
- Welters Ingeborg D.
- White Joanne
- White Nigel
- Whiteley Simon
- Whitticase Richard
- Wiborg Elisabeth
- Wijnands Patricia
- Wilby Liz
- Williams Anne
- Williams Ged
- Williams Helen
- Williams Karen
- Williams Lynne
- Wilting Rob
- Wise Robert
- Woods Justin
- Wright Kerry
- Wu Juan
- Wu ShiFen
- Wu Xiaojun
- Wu Xiaoying
- Wu Yang
- Wu Yun
- Wu Zijing
- Xhindi Nordian
- Xia Chun Jie
- Xia Xinhua
- Xiao Lina
- Xiao Min
- Xiao Yan
- Xiaoyan Yang
- Xie Yan
- Xing Cynthia
- Xiong Yunfeng
- Xixi Li
- Xu Lina
- Xu Xiao
- Xu Xuelian
- Xu Yan
- Xue Xiujuan
- Yaghi Aktham
- Yakubu Yakubu H.
- Yamamoto Ryohey
- Yan Howe
- Yan Xiaoli
- Yan Yan
- Yang Fan
- Yang Fengling
- Yang Huai
- Yang Jing
- Yang Lei
- Yang Qiao
- Yang Shunzhu
- Yang Yanping
- Yang YongXia
- Yao Xiuying
- Yao Yanlan
- Yao Zhiru
- Ye Man
- Ye Mei
- Yeni Nomhle Princess
- Yeon-Joo Lee
- Yildiz İsmail
- Yilmaz Hakan
- Yin Hai
- Yin Li
- Young Charlotte
- Young-Jae Cho
- Yu Jing
- Yu Min
- Yu Tingting
- Yu Zhu Jun
- Yuan Cui
- Yuan Weilian
- Yuan Yuxia
- Yuchen Wu
- Yuemen Ly
- Yumei Chen
- Zahra Hajer Ben
- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
- Zgrzheblovska Lesia
- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
- Zhang Libing
- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- 'Organisation for Economic Co-Operation and Development (OECD)'
- Publication date
- 26/02/2021
- Field of study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
Recommended from our members
Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Abdala Antonio
- Abidi Khalid
- Abillama Fayez François
- Abos Francisco Javier Saenz
- Aboufray Ahmed Ali
- Abregal Giancarlo
- Abroug Fekri
- Achilleos Eleni
- Acosta Ysica
- Adam Višnja Nesek
- Adamina Ileana
- Adams John
- Adamuz Jordi
- Adejumo Prisca Olabisi
- Adekola Oyebola
- Ademokun Jane
- Adenekan Anthony
- Adib Nik Azman Nik
- Adipa Faustina Excel
- Afonso Elsa
- Aganon Ferdinand
- Agarwal Sonika
- Aguirre Joaquin
- Aguirre Lydia Gallego
- Aguirre-Bermeo Hernan
- Ahmad Fatima Kasem El
- Ahmad Meraj
- Ahmed Hazem
- Ahn Jong-Joon
- Ahtiala Maarit
- Akbas Turkay
- Akdağ Devrim
- Akker Mustafa
- Akselsen Gro Ringstad
- Al-Alawi Maram Milud Said
- Alabuzidi Aya
- Alampi Daniela
- Albaiceta Guillermo Muñiz
- Albert Patricia
- Albrecht Lea
- Albrett Jonathan
- Alexandropoulou Paraskevi
- Alexandrou Anna
- Ali Ashwaq
- Ali Mohd Nazri
- Alias Anita
- Alkhumsi Soad Imhmed R.
- Allaert Silvie
- Allison Nicola
- Almekhlafi Ghaleb
- Alonso Helena Fernandez
- Alsheikhly Ahmed Subhy
- Alshrif Abdualhamid I
- Alvarenga Gloria
- Alvarez Diana
- Alvarez Gonzalo Martín
- Alvarez Gustavo Andres
- Alvarez Jorge Duerto
- Alvarez Josep Trenado
- Alvarez Raquel Garcia
- Alves Paulo
- Andersen Marit Hildegunn
- Andersen Yvonne
- Andresen Hanne
- Anisoglou Souzana
- Antonio Maria Gracia San
- Antunes Nelson
- Anvelt Eneli
- Aperocho Cristal April Jane
- Aponte Cesar
- Araya Paola
- Arcas María Luisa Bravo
- Arikan Huseyin
- Arntsen Wenche
- Arteta Arteta Donaldo S.
- Ashour Firas
- Assiri Amer
- Atchade Enora
- Ateya Zainab
- Attwood Ben
- Aucapina Alejandra
- Avalos Fernando
- Aves Emma
- Avogadro Prune
- Avramopoulou Lamprini
- Ay Mustafa
- Ay Serap Avcı
- Aya Umeda
- Ayala Maria
- Aydemir Semih
- Aydin Demet Tok
- Azencot Mazal
- Azoia Joao
- Baasanjav Battsetseg
- Babych Volodymyr
- Baccaro Fernando
- Badariotti Gustavo
- Bae Jung-Min
- Baek Jonghyun
- Baftiu Nehat
- Bagshaw Sean
- Bahrin Laila Kamaliah Kamalul
- Bai Dongmei
- Bai Xiaowu
- Baini Matías
- Bakas Apostolos
- Baker Helen
- Baker Nerilee
- Balasubramanian Madhu
- Balbay Abidin Oner
- Balon Sandrine
- Bantar Ana
- Banwarie Preveen
- Bao Guijun
- Baptiste-Savoie Jacqueline
- Barakat-Johnson Michelle
- Barefield Cindy
- Barkas Diane
- Barnes Christopher
- Barone Antonio
- Baronia Arvind
- Barr Louise
- Barreiro Emma Moreno
- Barros Elaine
- Barrowcliffe Suzanne
- Barrueco-Francioni Jesus Emilio
- Bartoli Julio Ricardo
- Baruah Rosaleen
- Bascary Carlos Alejandro
- Baskakov Danil
- Baskoro Windu
- Bastani Styliani
- Baumber Rachel
- Baxter Karen
- Bayraktar Yesim Serife
- Bealer Cheryl
- Bean Sarah
- Becker Cathy
- Becker Delmiro
- Behan Helena
- Beker Tatjana
- Bekos Vasileios
- Belii Adrian
- Belkhair Wesal Ali
- Belskiy Vladislav
- Ben-Hamouda Nawfel
- Ben-Jacob Talia
- Benbenishty Julie
- Bench Suzanne
- Bendelari Valentina
- Benlamin Mohamed
- Berry Gillian
- Bertoletti Fernando Pablo
- Besbes Lamia
- Besbes Lamia Ouanes
- Besch Guillaume
- Bestle Morten
- Beuret Pascal
- Bhakhtiani Lakshay
- Bhargava Vaibhav
- Bi AiPing
- Bianchini Suzana
- Bielskute Egidija
- Bilawicz Jan
- Binda Filipo
- Birgisdottir Hrönn
- Birgisdóttir Hrönn
- Bispo Bruno Miguel
- Biston Patrick
- Bjorgen Hege
- Blackwood Bronagh
- Blanc Agnès
- Blanco Daniel
- Blanco Maria Pilar Sogues
- Blasco Maria Luisa
- Bliksted Inger Abildgaard
- Blondal Asbjorn
- Bloos Frank
- Blot Stijn I.
- Bo Qi
- Bocui Nie
- Boedjawan Naraindath N.
- Bogarin Javier
- Bogoevska-Miteva Zaneta
- Bonaccorso Luciano
- Bongiorno Benjamin
- Bonsignore Pablo Julio Maldonaldo
- Borgognoni Cinzia
- Borin Christophe
- Borkowska Marta
- Bormans Laura
- Boroli Filippo
- Borys Michal
- Boschetto Margherita
- Bossolasco Matteo
- Bota Marc
- Boulanger Carole
- Boulton Karen
- Bowes Bonnie
- Boyer Laetitia
- Bozbay Suha
- Bozena Armanda
- Bratsberg Bjorn
- Bravo Silvina
- Brett Carole
- Brett Stephen
- Brett Stephen J.
- Briva Arturo
- Brizio Elisabetta
- Brizuela Patricia
- Broadhurst Phil
- Brown Wendy
- Browne Troy
- Bruel Cédric
- Bruhn Louise
- Brumwell Sarah
- Bruni Andrea
- Bruno Anna Vita
- Buckley Sarah
- Bull Rhian
- Bumbasirevic Vesna
- Buregeya Egide
- Burns Karen
- Butcher Rand
- Byers Heather
- Bösl Kathrin
- Cabral Dolly Mabel Bordon
- Cabral João
- Cabrita Paula
- Caddell Paul
- Caicedo Nestor
- Calamai Italo
- Calili Duygu Kayar
- Caliskan Gulbahar
- Calleja Pablo Lopez-Arcas
- Calpe Neus
- Calvino-Gunther Silvia
- Campanili Ticiane
- Campbell Elizabeth
- Campos Pierina Arias
- Campos-Perez Margarita
- Camputaro Luis
- Camsooksai Julie
- Canales Julieta
- Canete Fidelina
- Cani Alma
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- Cao Deyan
- Cao Wenzhen
- Cao Ying
- Cao Zu Qing
- Capuzzi Fabio
- Cardenas Yenny
- Carey Annette
- Carney Dominic
- Carter Charlotte
- Casaioli Simona
- Castelain Vincent
- Castiglione Giacomo
- Cata Juan
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- Cengiz Melike
- Cerezo Franklin Dean
- Cesar Helena
- Cespedes Laura
- Chaboyer Wendy
- Chadwick Llesley
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- Chang Youjin
- Chantziara Vasiliki
- Chao Yu
- Chaparro Javiera
- Chaparro Silvia
- Chapeta Edwin
- Chapman Carmel
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- Chen Feifei
- Chen Haiyan
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- Chen Zhihong
- Cheng
- Cheng Jiyin
- Chime Christiana
- Chimunda Tim
- Chinardet Benoît
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- Christ Martin
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- Chueca Ramon Molina
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- Cinel İsmail
- Ciorba Paolo
- Clark Michele
- Clement Ana Isabel
- Clesi Tara
- Cody Caitriona
- Collet Marie
- Collins Amy
- Coman Mary
- Conde Belen Burgos
- Conejo Isabel
- Constantinou Constantina
- Corcoran Ailesh
- Coremans Stefano
- Correia Malcolm C.
- Corso Amalia
- Cortegiani Andrea
- Cortellazi Paolo
- Cosano Rosario
- Cossu Maria
- Costa Humberto
- Cotoia Antonella
- Coyer Fiona
- Craig Geraldine
- Craig Jayne
- Cranmer Karen
- Cranshaw Julius
- Creber Peter
- Crone Petra
- Cui Xia
- Cummings Donna
- Cupitt Jason
- Curilen Veronica
- Czuczwar Miroslaw
- Dagooc Rica
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- Dal Hayriye Cankar
- Dallaire Julie
- Das Sasidharan Nair Vishnu
- Daubin Cédric
- Davidow Jon
- Davidson Cheryl
- Dawn Frances
- Dayan Meneses
- de Almeida Angelica Olivetto
- de Anda Gilberto Felipe Vazquez
- De Bels David
- de Ceballos José Peral Gutierrez
- De Decker Koen
- De Haan Marina
- de Jesús Ortiz Alberto
- de la Ventana Ana Belén Sánchez
- De lange Dylan
- De Lange Dylan
- de Molina Serrano José Ivan Rodriguez
- De Montmollin Etienne
- De Pablo Ana María
- De Rosa Silvia
- De Sanctis Francesca
- De Schryver Nicolas
- De Wit Irene
- Dean Emiliano
- Debue Anne-Sophie
- Del Bosque Diez Rosa
- del Cotillo Mercedes
- del Mar Diaz Salcedo Maria
- Del Moral Armengol Mario
- Del Rio Cabajo Lorena
- del Rosario Villar Redondo M.
- del Valle Gimenez Graciela
- Delgado Carlos Castro
- Delgado Patricia
- Dellafiore Federica
- Delossantos Shella
- Delve Peter
- Demarré Liesbet
- Demirkiran Oktay
- Dendane Tarek
- Deng Xiaoqiong
- Depuydt Tanja
- Derbyshire Claire
- Derrick Helen
- Deschepper Mieke
- Deva Shanti Rudra
- Dhaliwal Jasdeep
- Di Gravio Valentina
- Di Risio Alessandro
- Di Yanhong
- Diakaki Chrisi
- Dias Sofia
- Diaz Ana
- Diaz Anna
- Diaz Monica Garcia
- Dieperink Willem
- Diers Anja
- Dikmen Yalım
- Dikmen Yalim
- Dilek Ozcengiz
- Dimoula Aikaterini
- Dimski Thomas
- Ding Min
- Ding Xinran
- Ding Yajun
- Ding Yanming
- Dlamini-Sserumaga Lomangisi
- Dobric Milena
- Dolenc Simon
- Dolgusevs Mihails
- Domenech Laura Claramunt
- Dong Jingwen
- Dong Yunchun
- Donvito Maria
- Dormans Tom
- Douschan Philipp
- Doyle Deirdre
- Dragoumanis Christos
- Du Guifang
- Duan Huan
- Dugernier Thierry
- Duggal Abhijit
- Dullenkopf Alexander
- Dungca Adonis
- Dunne Lisa
- Duran Karely
- Déserts Marc Danguy des
- D’Ambrosio Francesco
- D’Ambrosio Paolo
- Ebaid Maie
- Ebaid Maie Salem
- Efe Serdar
- Efthimiou Aikaterini
- Efthymiou Anna
- Egi Moritoki
- Egorova Natalya
- Ei Poe Poe
- Elatrous Souheil
- Elay Gülseren
- Elgammudi Mala
- Elhadi Ahmed
- Elhadi Muhammed
- Elhechmi Youssef Zied
- Elkhayari Mina
- Ellazar Chris Gerome
- Eller Philipp
- Eltorai Ashley Szabo
- Enamorado Judy
- Enamorado Judy Enamorado
- Eneas Antony
- Eng Timothy
- Erdivanli Başar
- Erdogan Elif
- Eroglu Ahmet
- Ershova Olga
- Escalante Rosana Gabriela
- Espinosa Cristina Paños
- Esposito Romina
- Essardy Fatiha
- Etourneau Fabienne
- Evers Mirjam
- Fadeeva Liudmila
- Fan Limei
- Fang Xiuhua
- Farkas Jean-christophe
- Farmakis Epaminontas
- Farnell-Ward Sarah
- Farre Olga
- Fartoukh Muriel
- Favre René
- Feghaly Michel El
- Fei Qin
- Feng ZhangXia
- Feng Zhaoxia
- Feranandes Ana Margarida
- Fernadez Inmaculada Lorenzo
- Fernandes Fatima
- Fernandez Alejandra Azahara Marguello
- Fernandez Maria Alejandra
- Fernandez Maria Cristina Iglesias
- Fernandez Oscar
- Fernandez Ruben
- Fernandez Silvia
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- Tubacka Marta
- Tuinstra Binny
- Tuo Lili
- Turan Can
- Turan Sema
- Turc Jean
- Turner Sarah Jane
- Turčan Anton
- Tutillo Diego Rolando Morocho
- Twagirumugabe Theogene
- Twiggs Hilary
- Uba Stella
- Uccelli Francesco
- Udiljak Nikolina
- Ugwu Innocent
- Umek Nejc
- Undar Hasan Nabi
- Vakalos Aristeidis
- Valerio Idália
- Valgolio Emanuel
- Valta Maija
- Valta Maija Anniina
- van Axel Alisha
- Van Cotthem Ilse
- Van de Velde Stijn
- Van Den Berg Lettie
- Van Den Brink Mark
- Van Den Elst Arlette
- van der Kuil Mark
- Van Gulik Laura
- Van Regenmortel Niels
- Van Vliet Peter
- Vanroest Margijske
- Varela Maria
- Vaschetto Rosanna
- Vasquez Alexandra
- Vaughan-Jones Nicola
- Velickovic Jelena
- Veličković Dejan
- Ventour Dale
- Vermeijden Jan Wytze
- Vieira João
- Villa Robert
- Villafuerte Missael Vladimir Espinoza
- Villanueva Ximena
- Villegas Paula
- Viveiros Abel
- Vizcaychipi Marcela
- Vlaovic Janko
- Vochin Ana
- Volta Carlo Alberto
- von der Osten Ingrid
- Von Der Osten Ingrid
- von Lewinski Dirk
- Vosylius Saulius
- Vuković Anita
- Vullum Sylvi
- Vymazal Tamas
- Vymazal Tomas
- Wahab Sherliza
- Wahlbom Ewa
- Waibel Hansjoerg
- Wallin Ewa
- Walsh Amy
- Wan Jianhong
- Wan Yan
- Wang Damei
- Wang Fanglan
- Wang GuoXian
- Wang Hai Yun
- Wang Haiyan
- Wang Jing
- Wang Kefang
- Wang LingLing
- Wang RuiXia
- Wang Shuhui
- Wang Shuo
- Wang Wei
- Wang Wenmei
- Wang Xiaomin
- Wang Yan
- Wang Ying
- Wang Yingli
- Wang Yuping
- Wang Yuxia
- Watts Stacey
- Waweru-Siika Wangari
- Wei Dongfang
- Wei Wei
- Wei Xiyan
- Wei Ying
- Welters Ingeborg D.
- White Joanne
- White Nigel
- Whiteley Simon
- Whitticase Richard
- Wiborg Elisabeth
- Wijnands Patricia
- Wilby Liz
- Williams Anne
- Williams Ged
- Williams Helen
- Williams Karen
- Williams Lynne
- Wilting Rob
- Wise Robert
- Woods Justin
- Wright Kerry
- Wu Juan
- Wu ShiFen
- Wu Xiaojun
- Wu Xiaoying
- Wu Yang
- Wu Yun
- Wu Zijing
- Xhindi Nordian
- Xia Chun Jie
- Xia Xinhua
- Xiao Lina
- Xiao Min
- Xiao Yan
- Xiaoyan Yang
- Xie Yan
- Xing Cynthia
- Xiong Yunfeng
- Xixi Li
- Xu Lina
- Xu Xiao
- Xu Xuelian
- Xu Yan
- Xue Xiujuan
- Yaghi Aktham
- Yakubu Yakubu H.
- Yamamoto Ryohey
- Yan Howe
- Yan Xiaoli
- Yan Yan
- Yang Fan
- Yang Fengling
- Yang Huai
- Yang Jing
- Yang Lei
- Yang Qiao
- Yang Shunzhu
- Yang Yanping
- Yang YongXia
- Yao Xiuying
- Yao Yanlan
- Yao Zhiru
- Ye Man
- Ye Mei
- Yeni Nomhle Princess
- Yeon-Joo Lee
- Yildiz İsmail
- Yilmaz Hakan
- Yin Hai
- Yin Li
- Young Charlotte
- Young-Jae Cho
- Yu Jing
- Yu Min
- Yu Tingting
- Yu Zhu Jun
- Yuan Cui
- Yuan Weilian
- Yuan Yuxia
- Yuchen Wu
- Yuemen Ly
- Yumei Chen
- Zahra Hajer Ben
- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
- Zgrzheblovska Lesia
- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
- Zhang Libing
- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- Intensive Care Medicine
- Publication date
- 09/04/2021
- Field of study
The original version of this article unfortunately contained a mistake
Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Aaron Joffe
- Aaron Mark Hernandez
- Aaron Mark Hernandez
- Abby Lewis
- Abdelhamid Hachimi
- Abdualhamid I Alshrif
- Abel Viveiros
- Abhijit Duggal
- Abidin Oner Balbay
- Achilleas Chovas
- Ade Susanti
- Adi Hadzibegovic
- Adonis Dungca
- Adrian Belii
- Adrian Belii
- Adriana Onelli
- Afolabi Owojuyigbe
- Agnieszka Kubisz-Pudelko
- Agnès Blanc
- Ahmed Ali Aboufray
- Ahmed Elhadi
- Ahmed Ramadan Triki
- Ahmed Subhy Alsheikhly
- Ahmed Zaki
- Ahmet Eroglu
- Aidan O'Shea
- Aikaterini Dimoula
- Aikaterini Efthimiou
- Aikaterini Flevari
- Ailesh Corcoran
- AiPing Bi
- Aiua Ren
- Aizhi Zhang
- Ajitha Rajendran
- Akemi Hirao
- Akira Ohuchi
- Aktham Yaghi
- Ala Khaled
- Alan Sustic
- Alan Sustic
- Alba Riera
- Alban Greca
- Alberto de Jesús Ortiz
- Alberto Peratoner
- Alejandra Aucapina
- Alejandra Azahara Marguello Fernandez
- Alejandro Ibarra
- Aleksandar Šuput
- Aleksandra Gutysz-Wojnicka
- Alessandra Negro
- Alessandro Di Risio
- Alessandro Galazzi
- Alexander Dullenkopf
- Alexander Kiselev
- Alexander Tsarev
- Alexandra Pivkina
- Alexandra Vasquez
- Alexis Tabah
- Ali Kağnıcı
- Alida Moise
- Aline Ramalho
- Alinoy Lavy
- Alisha van Axel
- Alma Cani
- Alvaro Ortega Guerrero
- Amalia Corso
- Amber Markham
- Amelia Ferreira
- Amer Assiri
- Amilcar Garcia
- Amilcar Garcia
- Amit Gupta
- Amit Gupta
- Amy Collins
- Amy Thompson
- Amy Walsh
- Amylkar Garay Reyes
- Amylkar José Garay Reyes
- Ana Alabart Llinas
- Ana Alícia Velarde Pineda
- Ana Bantar
- Ana Belén Curto Polo
- Ana Belén Sánchez de la Ventana
- Ana Diaz
- Ana Diaz
- Ana Isabel Clement
- Ana Laura Gonzalez
- Ana Lucia Vitti Ronchini
- Ana Margarida Feranandes
- Ana María De Pablo
- Ana Pascual-Bielsa
- Ana Tavares
- Ana Vochin
- Ana Wensell Fernández
- Anastasia Spyropoulou
- Anastasio Espejo Cano
- Andeas Stübner
- Andrea Bruni
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Giampaoletti
- Andrea Martonova
- Andrea Martonova
- Andrea McDonnell
- Andrea McLucas
- Andrej Markota
- Andrijan Kartalov
- Andréa Maria Laizner
- Andréa Maria Laizner
- Andréa Maria Laizner
- Ane Stenset
- Angela Trposak
- Angelica Olivetto de Almeida
- Anisette Hoegenhaven
- Anita Alias
- Anita Jans
- Anita Vuković
- Anita-Chrysolyte Kusi-Appiah
- Anja Diers
- Anja Hansen
- Ann-Sofie Malvemyr
- Anna Alexandrou
- Anna Diaz
- Anna Efthymiou
- Anna Kyriakoudi
- Anna Leonova
- Anna Vita Bruno
- Anne Fishman
- Anne Langvad
- Anne Marie Kodal
- Anne Sofie Bomholt Pedersen
- Anne Williams
- Anne-Sophie Debue
- Annette Carey
- Annette Toellefsen
- Anthony Adenekan
- Anthony Radavidson
- Antigoni Karathanou
- Anton Turčan
- Antonella Cotoia
- Antonella Mo
- Antoni Margarit Ribas
- Antonia Liarmakopoulou
- Antonija Petosic
- Antonino Rizzo
- Antonio Abdala
- Antonio Barone
- Antonio Landaverde
- Antonio Manzo
- Antonio Margarit Ribas
- Antony Eneas
- Apostolos Bakas
- Arena Raimondo
- Arif Moghal
- Aristeidis Vakalos
- Arlette Van Den Elst
- Armanda Bozena
- Armando Schmukler
- Armorel Salberg
- Artemis Patsalos
- Arturo Briva
- Arvind Baronia
- Asbjorn Blondal
- Ascanio Tridente
- Ashish K Khanna
- Ashish K Khanna
- Ashish Khanna
- Ashley Szabo Eltorai
- Ashok Sundai Raj
- Ashwaq Ali
- Asmah Zainudin
- Asu Ozgultekin
- Ata Mahmoodpoor
- Athena Lavrentieva
- Attilio Quaini
- Audrey Fioretti
- Audrey Massard
- Auke Reidinga
- Auli Palmu
- Avşar Zerman
- Aya Alabuzidi
- Ayako Noguchi
- Ayça Gümüş
- Azmin Huda Abdul Rahim
- Babangida John Sankey
- Badiola Hilario
- Banu Taşdemir
- Baoke Zhang
- Barbara Garcia
- Barbro Meland
- Bart Ramaker
- Basri Mat Nor
- Battsetseg Baasanjav
- Başar Erdivanli
- Başar Erdivanli
- Beatrice Pastore
- Begoña Zalba-Etayo
- Belen Burgos Conde
- Belinda Guadi-Gosh
- Ben Attwood
- Benjamin Bongiorno
- Benjamin Gerretsen
- Benoît Chinardet
- Berenice Navarro
- Bernardo Panka
- Bernardo Panka
- Bernd Oliver Rose
- Bert Loef
- Betty Star Kampayana
- Beverley Thomas
- Beysim Özcan
- Beysim Özcan
- Bhagyesh Shah
- Biljana Kuzmanovska
- Bindu Thankamma
- Bing Song
- Binny Tuinstra
- Birgitte Fosser Johansen
- Birthe Husted
- Biyan Li
- Bjoern Monsen
- Bjorn Bratsberg
- Bodin Khwannimit
- Bogdan Raitsiou
- Bojan Jovanovic
- Bonnie Bowes
- Boğaç Özserezli
- Bram Kilapong
- Bram Kilapong
- Branislava Stefanovic
- Brian Marsh
- Brigitte Tejeda-Huezo
- Brita Fosser Olsen
- Britt Galaaen
- Britt Sjobo
- Britta Jepsen
- Bronagh Blackwood
- Bruno Miguel Bispo
- Bruno Sousa
- Bruno Sousa
- Brynja Rygvadottir
- Burhan Hadri
- Burhan Hadri
- Byung Ju Kang
- Caihong Hui
- Caiju Song
- Caitriona Cody
- Can Turan
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- Charlotte Young
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- Cheng
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- Chrysostomos Katsenos
- Chun Jie Xia
- Chunxia Li
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- Cyril Thix
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- Daisy Mehay
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- Damien O'Connell Rosemary Finn
- Dana Tomescu
- Dana Tomescu
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- Daniel Blanco
- Daniel Horner
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- Danielle Hacking
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- Davide Massimo Ghioldi
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- Debbie Noblezada-Uy
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- DeHong Lei
- Deirdre Doyle
- Dejan Veličković
- Delmiro Becker
- Delphine Ngo
- Demet Tok Aydin
- Detlef Kindgen-Milles
- Devrim Akdağ
- Deyan Cao
- Diana Alvarez
- Diane Barkas
- Dianne Figaro-Barclay
- Dick Nahar
- Diego Rolando Morocho Tutillo
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- Dmitry Sergeev
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- Dritan Muzha
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- Dylan De Lange
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- Elizabeth Maidana
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- Elsa Afonso
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- Emilio Maseda
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- Emma Moreno Barreiro
- Emma Parkin
- Enas Soula
- Eneli Anvelt
- Enora Atchade
- Epaminontas Farmakis
- Erik Roman-Pognuz
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- Eryun Tian
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- Eva Joelsson-Alm
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- Fayez François Abillama
- Fayez François Abillama
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- Federico Gordo
- Federico Iglesias
- Fei Ouyang
- Feifei Chen
- Feifei Luo
- Feifei Zhang
- Fekri Abroug
- Fengling Yang
- Ferdinand Aganon
- Fernando Avalos
- Fernando Baccaro
- Fernando Lipovestky
- Fernando Lipovesty
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- Jing Li
- Jing Li
- Jing Li
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- Jing Yang
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- Jingfang Chen
- Jingfang Chen
- Jingwen Dong
- Jingyu Liu
- Jinhua Li
- JinHui Song
- Jinxian Liang
- Jisoo Park
- Jiye Guo
- Jiyin Cheng
- Jo Jones
- Joanne White
- Joao Azoia
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- Yuping Wang
- Yuxia Huo
- Yuxia Wang
- Yuxia Yuan
- Yvan Fleury
- Yvonne Andersen
- Zainab Ateya
- Zaneta Bogoevska-Miteva
- Zeya Shi
- Zhang Zhigang
- ZhangShuangzi Li
- ZhangXia Feng
- Zhaoxia Feng
- Zhaoxing Dai
- Zhenxia Zhang
- Zhihong Chen
- Zhiru Yao
- Zhixia Jiang
- ZhiXia Jiang
- Zhixia Tian
- Zhu Jun Yu
- Zhuqing Li
- Zied Hajjej
- Zijing Wu
- Zsuzsann Ágoston
- Zu Qing Cao
- Zulkifli Zulkifli
- Ângela Lima
- Publication venue
- Intensive Care Medicine
- Publication date
- 29/08/2020
- Field of study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
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- Aali Amirali
- Ababneh Hazim S
- Abate Yohannes Habtegiorgis
- Abbafati Cristiana
- Abbasgholizadeh Rouzbeh
- Abbasi-Kangevari Mohsen
- Abbasian Mohammadreza
- Abbastabar Hedayat
- Abd ElHafeez Samar
- Abd-Elsalam Sherief
- Abdelmasseh Michael
- Abdelwahab Ahmed
- Abdollahi Mohammad
- Abdollahifar Mohammad-Amin
- Abdoun Meriem
- Abdulah Deldar Morad
- Abdullahi Auwal
- Abebe Mesfin
- Abebe Samrawit Shawel
- Abedi Aidin
- Abegaz Kedir Hussein
- Abhilash E S
- Abidi Hassan
- Abiodun Olumide
- Aboagye Richard Gyan
- Abolhassani Hassan
- Abolmaali Meysam
- Abouzid Mohamed
- Aboye Girma Beressa
- Abreu Lucas Guimarães
- Abrha Woldu Aberhe
- Abtahi Dariush
- Abu Rumeileh Samir
- Abu-Gharbieh Eman
- Abu-Rmeileh Niveen ME
- Abu-Zaid Ahmed
- Abualruz Hasan
- Abubakar Bilyaminu
- Aburuz Salahdein
- Accrombessi Manfred Mario Kokou
- Adal Tadele Girum
- Adamu Abdu A
- Addo Isaac Yeboah
- Addolorato Giovanni
- Adebiyi Akindele Olupelumi
- Adekanmbi Victor
- Adepoju Abiola Victor
- Adetunji Charles Oluwaseun
- Adetunji Juliana Bunmi
- Adeyeoluwa Temitayo Esther
- Adeyinka Daniel Adedayo
- Adeyomoye Olorunsola Israel
- Admass Biruk Adie Adie
- Adnani Qorinah Estiningtyas Sakilah
- Adra Saryia
- Afolabi Aanuoluwapo Adeyimika
- Afzal Muhammad Sohail
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- Agyemang-Duah Williams
- Ahinkorah Bright Opoku
- Ahmad Aqeel
- Ahmad Danish
- Ahmad Firdos
- Ahmad Muayyad M
- Ahmad Sajjad
- Ahmad Shahzaib
- Ahmad Tauseef
- Ahmadi Keivan
- Ahmadzade Amir Mahmoud
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- Al-Maweri Sadeq Ali Ali
- Al-Mekhlafi Hesham M
- Al-Omari Basem
- Al-Sabah Salman Khalifah
- Al-Tawfiq Jaffar A
- Al-Worafi Yaser Mohammed
- Alahdab Fares
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- Alcalde-Rabanal Jacqueline Elizabeth
- Aldawsari Khalifah A
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- Alema Haileselasie Berhane
- Alemayohu Mulubirhan Assefa
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- Socea Bogdan
- Sokhan Anton
- Solanki Ranjan
- Solanki Shipra
- Soleimani Hamidreza
- Soliman Sameh S M
- Song Suhang
- Song Yimeng
- Sorensen Reed J D
- Soriano Joan B
- Soyiri Ireneous N
- Spartalis Michael
- Spearman Sandra
- Sreeramareddy Chandrashekhar T
- Srivastava Vijay Kumar
- Stanaway Jeffrey D
- Stanikzai Muhammad Haroon
- Stark Benjamin A
- Starnes Joseph R
- Starodubova Antonina V
- Stein Caroline
- Stein Dan J
- Steinbeis Fridolin
- Steiner Caitlyn
- Steinmetz Jaimie D
- Steiropoulos Paschalis
- Stevanović Aleksandar
- Stockfelt Leo
- Stokes Mark A
- Stortecky Stefan
- Subramaniyan Vetriselvan
- Suleman Muhammad
- Suliankatchi Abdulkader Rizwan
- Sultana Abida
- Sun Haitong Zhe
- Sun Jing
- Sundström Johan
- Sunkersing David
- Sunnerhagen Katharina S
- Swain Chandan Kumar
- Szarpak Lukasz
- Szeto Mindy D
- Szócska Miklós
- Tabaee Damavandi Payam
- Tabarés-Seisdedos Rafael
- Tabatabaei Malazy Ozra
- Tabatabaei Seyyed Mohammad
- Tabatabaeizadeh Seyed-Amir
- Tabatabai Shima
- Tabish Mohammad
- TADAKAMADLA JYOTHI
- Tadakamadla Santosh Kumar
- Taheri Abkenar Yasaman
- Taheri Soodejani Moslem
- Taiba Jabeen
- Takahashi Ken
- Talaat Iman M
- Talukder Ashis
- Tampa Mircea
- Tamuzi Jacques Lukenze
- Tan Ker-Kan
- Tandukar Sarmila
- Tang Haosu
- Tang Hong K
- Tarigan Ingan Ukur
- Tariku Mengistie Kassahun
- Tariqujjaman Md
- Tarkang Elvis Enowbeyang
- Tavakoli Oliaee Razieh
- Tavangar Seyed Mohammad
- Taveira Nuno
- Tefera Yibekal Manaye
- Temsah Mohamad-Hani
- Temsah Reem Mohamad Hani
- Teramoto Masayuki
- Tesler Riki
- Teye-Kwadjo Enoch
- Thakur Rishu
- Thangaraju Pugazhenthan
- Thankappan Kavumpurathu Raman
- Tharwat Samar
- Thayakaran Rasiah
- Thomas Nihal
- Thomas Nikhil Kenny
- Thomson Azalea M
- Thrift Amanda G
- Thum Chern Choong Chern
- Thygesen Lau Caspar
- Tian Jing
- Tichopad Ales
- Ticoalu Jansje Henny Vera
- Tillawi Tala
- Tiruye Tenaw Yimer
- Titova Mariya Vladimirovna
- Tonelli Marcello
- Topor-Madry Roman
- Toriola Adetunji T
- Torre Anna E
- Touvier Mathilde
- Tovani-Palone Marcos Roberto
- Tran Jasmine T
- Tran Nghia Minh
- Trico Domenico
- Tromans Samuel Joseph
- Truyen Thien Tan Tri Tai
- Tsatsakis Aristidis
- Tsegay Guesh Mebrahtom
- Tsermpini Evangelia Eirini
- Tumurkhuu Munkhtuya
- Tung Kang
- Tyrovolas Stefanos
- Uddin Sayed Mohammad Nazim
- Udoakang Aniefiok John
- Udoh Arit
- Ullah Atta
- Ullah Irfan
- Ullah Saeed
- Ullah Sana
- Umakanthan Srikanth
- Umeokonkwo Chukwuma David
- Unim Brigid
- Unnikrishnan Bhaskaran
- Unsworth Carolyn Anne
- Upadhyay Era
- Urso Daniele
- Usman Jibrin Sammani
- Vahabi Seyed Mohammad
- Vaithinathan Asokan Govindaraj
- Valizadeh Rohollah
- Van de Velde Sarah M
- Van den Eynde Jef
- Varga Orsolya
- Vart Priya
- Varthya Shoban Babu
- Vasankari Tommi Juhani
- Vasic Milena
- Vaziri Siavash
- Vellingiri Balachandar
- Venketasubramanian Narayanaswamy
- Verghese Nicholas Alexander
- Verma Madhur
- Veroux Massimiliano
- Verras Georgios-Ioannis
- Vervoort Dominique
- Villafañe Jorge Hugo
- Villanueva Gabriela Ines
- Vinayak Manish
- Violante Francesco S
- Viskadourou Maria
- Vladimirov Sergey Konstantinovitch
- Vlassov Vasily
- Vo Bay
- Vollset Stein Emil
- Vongpradith Avina
- Vos Theo
- Vujcic Isidora S
- Vukovic Rade
- Wafa Hatem A
- Waheed Yasir
- Wamai Richard G
- Wang Cong
- Wang Ning
- Wang Shu
- Wang Song
- Wang Yanzhong
- Wang Yuan-Pang
- Waqas Muhammad
- Ward Paul
- Wassie Emebet Gashaw
- Watson Stefanie
- Watson Stephanie Louise Watson
- Weerakoon Kosala Gayan
- Wei Melissa Y
- Weintraub Robert G
- Weiss Daniel J
- Westerman Ronny
- Whisnant Joanna L
- Wiangkham Taweewat
- Wickramasinghe Dakshitha Praneeth
- Wickramasinghe Nuwan Darshana
- Wilandika Angga
- Wilkerson Caroline
- Willeit Peter
- Wilson Shadrach
- Wojewodzic Marcin W
- Woldegebreal Demewoz H
- Wolf Axel Walter
- Wolfe Charles D A
- Wondimagegene Yohannes Addisu
- Wong Yen Jun
- Wongsin Utoomporn
- Wool Eve E
- Wu Ai-Min
- Wu Chenkai
- Wu Felicia
- Wu Xinsheng
- Wu Zenghong
- Xia Juan
- Xiao Hong
- Xie Yang
- Xu Suowen
- Xu Wang-Dong
- Xu Xiaoyue
- Xu Yvonne Yiru
- Yadollahpour Ali
- Yamagishi Kazumasa
- Yang Danting
- Yang Lin
- Yano Yuichiro
- Yao Yao
- Yaribeygi Habib
- Ye Pengpeng
- Yehualashet Sisay Shewasinad
- Yesiltepe Metin
- Yesuf Subah Abderehim
- Yezli Saber
- Yi Siyan
- Yigezu Amanuel
- Yip Paul
- Yismaw Malede Berihun
- Yismaw Yazachew
- Yiğit Arzu
- Yiğit Vahit
- Yon Dong Keon
- Yonemoto Naohiro
- Yoon Seok-Jun
- You Yuyi
- Younis Mustafa Z
- Yousefi Zabihollah
- Yu Chuanhua
- Yu Yong
- Yuh Faith H
- Zadey Siddhesh
- Zadnik Vesna
- Zafari Nima
- Zakham Fathiah
- Zaki Nazar
- Zaman Sojib Bin
- Zamora Nelson
- Zand Ramin
- Zangiabadian Moein
- Zar Heather J
- Zare Iman
- Zarrintan Armin
- Zeariya Mohammed G M
- Zeinali Zahra
- Zhang Haijun
- Zhang Jianrong
- Zhang Jingya
- Zhang Liqun
- Zhang Yunquan
- Zhang Zhi-Jiang
- Zhao Hanqing
- Zhong Chenwen
- Zhou Juexiao
- Zhu Bin
- Zhu Lei
- Ziafati Makan
- Zielińska Magdalena
- Zitoun Osama A
- Zoladl Mohammad
- Zou Zhiyong
- Zuhlke Liesl J
- Zumla Alimuddin
- Zweck Elric
- Zyoud Samer H
- Ärnlöv Johan
- Šekerija Mario
- Publication venue
- Elsevier
- Publication date
- 01/01/2024
- Field of study
BACKGROUND Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mortality rates and life expectancy allow comparisons of the consequences of causes of death globally and over time, providing a nuanced understanding of the effect of these causes on global populations. METHODS The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 cause-of-death analysis estimated mortality and years of life lost (YLLs) from 288 causes of death by age-sex-location-year in 204 countries and territories and 811 subnational locations for each year from 1990 until 2021. The analysis used 56 604 data sources, including data from vital registration and verbal autopsy as well as surveys, censuses, surveillance systems, and cancer registries, among others. As with previous GBD rounds, cause-specific death rates for most causes were estimated using the Cause of Death Ensemble model-a modelling tool developed for GBD to assess the out-of-sample predictive validity of different statistical models and covariate permutations and combine those results to produce cause-specific mortality estimates-with alternative strategies adapted to model causes with insufficient data, substantial changes in reporting over the study period, or unusual epidemiology. YLLs were computed as the product of the number of deaths for each cause-age-sex-location-year and the standard life expectancy at each age. As part of the modelling process, uncertainty intervals (UIs) were generated using the 2·5th and 97·5th percentiles from a 1000-draw distribution for each metric. We decomposed life expectancy by cause of death, location, and year to show cause-specific effects on life expectancy from 1990 to 2021. We also used the coefficient of variation and the fraction of population affected by 90% of deaths to highlight concentrations of mortality. Findings are reported in counts and age-standardised rates. Methodological improvements for cause-of-death estimates in GBD 2021 include the expansion of under-5-years age group to include four new age groups, enhanced methods to account for stochastic variation of sparse data, and the inclusion of COVID-19 and other pandemic-related mortality-which includes excess mortality associated with the pandemic, excluding COVID-19, lower respiratory infections, measles, malaria, and pertussis. For this analysis, 199 new country-years of vital registration cause-of-death data, 5 country-years of surveillance data, 21 country-years of verbal autopsy data, and 94 country-years of other data types were added to those used in previous GBD rounds. FINDINGS The leading causes of age-standardised deaths globally were the same in 2019 as they were in 1990; in descending order, these were, ischaemic heart disease, stroke, chronic obstructive pulmonary disease, and lower respiratory infections. In 2021, however, COVID-19 replaced stroke as the second-leading age-standardised cause of death, with 94·0 deaths (95% UI 89·2-100·0) per 100 000 population. The COVID-19 pandemic shifted the rankings of the leading five causes, lowering stroke to the third-leading and chronic obstructive pulmonary disease to the fourth-leading position. In 2021, the highest age-standardised death rates from COVID-19 occurred in sub-Saharan Africa (271·0 deaths [250·1-290·7] per 100 000 population) and Latin America and the Caribbean (195·4 deaths [182·1-211·4] per 100 000 population). The lowest age-standardised death rates from COVID-19 were in the high-income super-region (48·1 deaths [47·4-48·8] per 100 000 population) and southeast Asia, east Asia, and Oceania (23·2 deaths [16·3-37·2] per 100 000 population). Globally, life expectancy steadily improved between 1990 and 2019 for 18 of the 22 investigated causes. Decomposition of global and regional life expectancy showed the positive effect that reductions in deaths from enteric infections, lower respiratory infections, stroke, and neonatal deaths, among others have contributed to improved survival over the study period. However, a net reduction of 1·6 years occurred in global life expectancy between 2019 and 2021, primarily due to increased death rates from COVID-19 and other pandemic-related mortality. Life expectancy was highly variable between super-regions over the study period, with southeast Asia, east Asia, and Oceania gaining 8·3 years (6·7-9·9) overall, while having the smallest reduction in life expectancy due to COVID-19 (0·4 years). The largest reduction in life expectancy due to COVID-19 occurred in Latin America and the Caribbean (3·6 years). Additionally, 53 of the 288 causes of death were highly concentrated in locations with less than 50% of the global population as of 2021, and these causes of death became progressively more concentrated since 1990, when only 44 causes showed this pattern. The concentration phenomenon is discussed heuristically with respect to enteric and lower respiratory infections, malaria, HIV/AIDS, neonatal disorders, tuberculosis, and measles. INTERPRETATION Long-standing gains in life expectancy and reductions in many of the leading causes of death have been disrupted by the COVID-19 pandemic, the adverse effects of which were spread unevenly among populations. Despite the pandemic, there has been continued progress in combatting several notable causes of death, leading to improved global life expectancy over the study period. Each of the seven GBD super-regions showed an overall improvement from 1990 and 2021, obscuring the negative effect in the years of the pandemic. Additionally, our findings regarding regional variation in causes of death driving increases in life expectancy hold clear policy utility. Analyses of shifting mortality trends reveal that several causes, once widespread globally, are now increasingly concentrated geographically. These changes in mortality concentration, alongside further investigation of changing risks, interventions, and relevant policy, present an important opportunity to deepen our understanding of mortality-reduction strategies. Examining patterns in mortality concentration might reveal areas where successful public health interventions have been implemented. Translating these successes to locations where certain causes of death remain entrenched can inform policies that work to improve life expectancy for people everywhere. FUNDING Bill & Melinda Gates Foundation
Contributions of residents from multiple specializations in managing the COVID-19 pandemic in the largest public hospital Brazil
- Author
- Publication venue
- Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
- Publication date
- 29/08/2020
- Field of study
Contributions of residents from multiple specializations in managing the COVID-19 pandemic in the largest public hospital Brazil
- Author
- Publication venue
- 'Fundacao Faculdade de Medicina'
- Publication date
- 01/01/2020
- Field of study
The Impact of Drug Trafficking on Informal Security Actors in Kenya
- Author
- Abrahamsen Rita
- Abrahamsen Rita
- Alemika Etannibi E. O.
- Alves Maria Helena Moreira
- Anderson David
- Archibold Randal C.
- Arias Enrique Desmond
- Bagley Bruce
- Baker Bruce
- Bayart Jean-François
- Bedoya Jairo
- Beittel June S.
- Botha Anneli
- Branch Daniel
- Buxton Julia
- Bybee Ashley Neese
- Cano Ignacio
- Carrier Neil
- Cawley Marguerite
- Clunan Anne L.
- Cockayne James
- Cornell Svante E.
- Cruz José Miguel
- Csete Joanne
- De Smedt Johan
- Dennis Emmanuel
- Deveau Clement
- Dudley Steven S.
- Ellis Stephen
- Ezrow Natasha M.
- Finnegan William
- Gambetta Diego
- Gastrow Peter
- Gastrow Peter
- Gay Robert
- Gay Robert
- Giraldo Javier
- Goldstein Donna
- Grayson George W.
- Guerrero-Gutiérrez Eduardo
- Hristov Jasmin
- Human Rights Watch
- Hume Mo
- Inkster Nigel
- Jacobs Andreas
- Jordan David C.
- Jütersonke Oliver
- Kagwanja Peter Mwangi
- Katumanga Musambayi
- Kenya National Commission on Human Rights
- Kinosian Sarah
- Klopp Jacqueline
- Koonings Kees
- Leeds Elisabeth
- Logan Samuel
- Madeira Luís Filipe
- Mandel Robert
- Mazzei Julie
- Menkhaus Ken
- Misse Michel
- Mueller Susanne D.
- Mutahi Patrick
- Ndung'u James
- Njonjo Katindi Sivi
- O'Donnell Guillermo
- O'Regan Davin
- Ogada Mikewa
- Okombo Okoth
- Patrick Stewart
- Penglase Ben
- Perlman Janice
- Pizarro Leongómez Eduardo
- Pécaut Daniel
- Report Waki
- Ribeiro Paulo Jorge
- Risse Thomas
- Rodgers Dennis
- Rodgers Dennis
- Rodgers Dennis
- Rodgers Dennis
- Roessler Philip
- Rozema Ralph
- Ruteere Mutuma
- Ruteere Mutuma
- Salazar Alonso
- Scheye Eric
- Servant Jean-Christophe
- Shay Shaul
- Southall Roger
- Stanislawski Bartosz H.
- Stepputat Finn
- Sullivan John
- Thornberry William
- Thoumi Francisco E.
- Tuckman Jo
- Valdez Al
- Volkov Vadim
- Wamucii Priscilla
- Weber Max
- Williams Phil
- Wyler Liana Sun
- Zilberg Elana
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
Guidance on mucositis assessment from the MASCC Mucositis Study Group and ISOO: an international Delphi studyResearch in context
- Author
- Abdul Rahman Al-Azri
- Abhijna Vithal Yergolkar
- Abhishek Kandwal
- Abhishek Kandwal
- Adel Kauzman
- Adrian Ramseier
- Adriana Do Socorro Lima Flato
- Adriana Sesti Paz
- Adwaita Gore
- Agnes Horvath
- Aisha Al-Jamaei
- Alan Santos-Silva
- Aleksandra Polonskaia
- Alessandra Majorana
- Alessandro Villa
- Alexa Laheij
- Alexandre Giannini
- Alexandre Melo
- Alina Markova
- Alisha Morgan
- Alison Melvin
- Allan Hovan
- Aluísio Miranda Filho
- Aléxia Teixeira
- Amanda Gruza
- Amber Brown-Dahl
- Amit Harilall
- Amr El Maghrabi
- Ana Andabak Rogulj
- Ana Carolina Ribeiro
- Ana Laura Soares
- Ana Raphaela Curvo
- Andrea Stringer
- Andrew Mazar
- Andréa Moreira
- Andy Kurtzweil
- Angela Thermann
- Angelyn Salaberry
- Anne Blazy
- Anne Margrete Gussgard
- Anne Marie Lynge Pedersen
- Anne-Marie Hardman
- Annette Freidank
- Antonio Carlos Moura de Melo
- Anura Ariyawardana
- Arghavan Tonkaboni
- Ariel Blanchard
- Augusto Poropat
- Aya koizumi
- Azael Freites-Martinez
- Barbara Ballantyne
- Bella Van Sebille
- Bengt Hasséus
- Benjamin Kaffenberger
- Bente Brokstad Herlofson
- Bernar Benites
- Bernice Kwong
- Beth Test
- Bo Pettersson
- Bomi Framroze
- Božana Lončar Brzak
- Brian Muzyka
- Brittany Dulmage
- Callie Gross
- Camila Rossi
- Carlos Mantelato
- Carlton Brown
- Caroline Fulop
- Caroline Margina Speksnijder
- Caroline Silva
- Caroline Spekssnijder
- Carolyn Patrick
- Carryn Anderson
- Catherine Flaitz
- Catherine Hong
- Catherine Poh
- Cathy Massoud
- Cesar Freytes
- Cesar Migliorati
- Cesar Virgen
- Charles Loprinzi
- Charlotte de Mooij
- Chiara Gandini
- Christine Boers-Doets
- Cibele Nagano
- Courtney Subramaniam
- Cristina Del Conte
- Cristina Neuenschwander
- Cynthia Rybczyk
- Dale Weaver
- Daniel Cohen Goldemberg
- Daniel Sundaresan
- Daniela Nunes
- Daniela Ribeiro
- Danyel Perez
- Daphine Travassos
- David Yang
- Dean Kolbinson
- Deborah Buick
- Deborah Buick
- Deborah Manne
- Deborah Saunders
- Deepika Chugh
- Denise Markstrom
- Denise Travassos
- Dennis Abbott
- Dianna Weikel
- Dimitra Galiti
- Dinusha Peiris
- Doreen Pon
- Dorothea Riesenbeck
- Dorothy Keefe
- Dorothy Keefe
- Douglas Fonseca
- Douglas Peterson
- Edmund Peters
- Eduardo Fregnani
- Eduardo Rodrigues Fregnani
- Elaci Cardoso
- Elena Bardellini
- Elena Volkova
- Eleni Arvanitou
- Eli Ehrenpreis
- Elisa Kauark Fontes
- Elisa Kauark-Fontes
- Elise Bruning
- Eloise Neumann
- Elsa Madureira
- Emma McCurdy-Franks
- Emmanuelle Vigarios
- Erofili Papadopoulou
- Esther Adebayo-Olojo
- Eszter Somogyi-Ganss
- Etiene Munhoz
- Evgeniya Shatokhina
- Fabiana Granzotto
- Fabiana Martins
- Fabio Alves
- Farah Mougeot
- Federica Aielli
- Fedja Djordjevic
- Felipe Sperandio
- Fernanda Fonseca
- Fernanda Pigatti
- Fernando Chiantia
- Firoozeh Samim
- Flavia Carvalho
- Florence Cuadra Zelaya
- Fred Spijkervet
- Gabriela da Silveira
- Gabriela Martins
- Gabriela Torino
- Geisa Silva
- Gemma Bryan
- Gemma Caro
- George Taybos
- Georgette Radford
- Georgios Gkardiakos
- Ghanyah Al-Qadami
- Giorgia Albini
- Gisele Mainville
- Giulia Ottaviani
- Giulia Ottaviani
- Gleidston Potter
- Gordon Howarth
- Grace Bradley
- Gulbin Hoeberechts
- Gunjan Verma
- Gustavo dos Santos
- Hanlie Engelbrecht
- Hannah Rose Wardill
- Hannah Wardill
- Hans Peter Jungbluth
- Heidi Hansen
- Helen McInnes
- Helena Ullgren
- Heliton Spindola Antunes
- Heloísa Laís dos Santos
- Hironobu Hata
- Howard Weld
- Hsiaofen Weng
- Ian Hewson
- Ikuko Komo
- Ines Semendric
- Inger Von Bultzingslowen
- Ingrid Santos
- Iona Leong
- Iquebal Hasan
- Ira Parker
- Isabella Fonseca
- Isadora Kalif
- Iuliia Kovalenko
- Ivana Skrinjar
- Jacqui Scott
- James Carroll
- Jane Fall-Dickson
- Janet Coller
- Jann Arends
- Januaria Passos
- Jasna Leko
- Jaya Amaram-Davila
- jaya Vangara
- Jean-Luc Mougeot
- Jennifer Powers
- Jesus Gomez
- Jim Siderov
- Jimma Lenjisa
- Joan Fox
- Joana Marinho
- Joanne Bowen
- Jocelyn Harding
- Joel Epstein
- Joel Epstein
- Joel Finkelstein
- Johann Beck-Mannagetta
- Jolien Robijns
- Jonn Wu
- Jorge Illarramendi
- Jose Meurer
- Judith Raber-Durlacher
- Judith Raber-Durlacher
- Julia Bruno
- Julia Néri
- Juliana Brito
- Juliana Dantas
- Juliana Jasper
- Juliana Monteiro
- Juliane De Bortolli
- julie pfeffer
- Julija Jovanovic Ristivojevic
- Jyothsna Kuriakose
- Kanan Dave
- Karen Biggs
- Karin Barczyszyn
- Karol Sartori Lima
- Kate Cooper
- Kate Secombe
- Kate White
- Katharine Ciarrocca
- Kathryn Ruddy
- Katia Rupel
- Katia Uezu
- Katrina Cao
- Keiko Tanaka
- Ken Tomizuka
- Keng Yeoh
- Kevin Hendler
- Kevin Saganski
- Kivanc Bektas-Kayhan
- Kouji Katsura
- Kristina Skallsjö
- Kristopher Dennis
- Kristy Hodgins
- Kunal Jain
- Larissa Agatti
- Laura Garzona-Navas
- Leah van Draanen
- Leila Portela
- Leilani Iossi
- Lene Baad-Hansen
- Leonard Schmeel
- Leslie Reeder
- Leticia Lang
- Letícia Guerra
- Liciane Menezes
- Liliana Braun
- Liliane Grando
- Lina Fernandez
- Linda Elting
- Luana Campos
- Luciana Muniz
- Luciana S Barbosa Barbosa
- Luciana Simonato
- Lucy McKeage
- Luiz Gueiros
- Madhup Rastogi
- Mahfujul Riad
- Mahnoor Nazar
- Manoela Pereira
- Marcia Ramires
- Marco Andrade
- Marco Montezuma
- Marcos Santos
- Margaret Randles-Guzzardi
- Margherita Gobbo
- Maria Caterina Fortuna
- Maria Choy
- Maria Coeli Franco
- Maria Cristina Gomez Amarilla
- Maria da Gloria de Melo
- Mariana Minamisako
- Mariana Vitor
- Marie-Therese Genot
- Mark Chambers
- Marlyse Knuchel
- Marta Carlesimo
- Marta Neves
- Martin Hauer-Jensen
- Maryam Taleghani
- Masatoshi Usubuchi
- Mathew Lim
- Maíra Souza
- Melissa de Araujo
- Melody Cole
- Micaela Bouchacourt
- Michael Brennan
- Michael Dougan
- Michael Kase
- Michael Thirlwell
- Michio Nakamura
- Midori Nakagaki
- Mieko Mizutani
- Mireille Kaprilian
- Mohamed Elsayed
- Monica Fliedner
- Monique Stokman
- Muhammad Ali Shazib
- Mukund Seshadri
- Márcio Diniz-Freitas
- Nancy Batista
- Nancy Corbitt
- Nancy Gadd
- Naoko Tanda
- Narmin Nasr
- Natalia Palmier
- Nathan Lee
- Natália Garcia
- Neli Pieralisi
- Nicola Alessandro Iacovelli
- Nicole Blijlevens
- Nicole Blijlevens
- Nikolaos Tsoukalas
- Niveditha Venkatesh
- Noam Yarom
- Norma Lúcia Sampaio
- Norman Brito-Dellan
- Nour Karra
- Olivia Lemenchick
- Ondina Mendes
- Ourania Nicolatou-Galitis
- Pamela Gardner
- Pankaj Singhai
- Paolo Bossi
- Paolo Bossi
- Patricio Palma
- Paula Reis
- Paula Silva
- Paulo Sérgio Santos
- Paz Fernandez-Ortega
- Peter Fritz
- Petter Wilberg
- Pierluigi Bonomo
- Pierluigi Bonomo
- Pierre Saint Girons
- Pramod Sankar S
- Pravin Chaturvedi
- Priscila Andrade
- Priya Tiwari
- Rachel Gibson
- Rachita Gururaj
- Ragda Abdalla-Aslan
- Ragda Abdalla-Aslan
- Raghu Thota
- Ragnhild Monsen
- Raj Nair
- Rajan Saini
- Rajesh Lalla
- Rania Abasaeed
- Raquel Almeida Prado
- Raquel García
- Ravikiran Ongole
- Regina Mackey
- Renata Camilotti
- Renata Cristina Borin
- Renata Ferrari
- Renata Rego
- Renato Junior
- Rene-Jean Bensadoun
- Richard Logan
- Ricky McCullough
- Robert Miller
- Robert Miller
- Roberta Sales
- Roberta Tunes
- Roberta Zanicotti
- Rodolfo Mauceri
- Rogério Caldas
- Rol Menge
- Rosiene Feitoza
- Rui Amaral Mendes
- Rui Amaral Mendes
- Sachiko Seo
- Sachiyo Mitsunaga
- Sahani Gunathilake
- Sandip Mukhopadhyay
- Sandra Reese
- Sandrina Angeloz
- Satheeshkumar Poolakkad Sankaran
- Seema Kurup
- Sergio Cantoreggi
- Sharon Elad
- Sharon Gordon
- Shelly Brown
- Shu Yie Janine Tam
- Sibelle Faleiro
- Silmara da Silva
- Silvia de Oliveira
- Siri Beier Jensen
- Sitaraman BalajiSubramanian
- Sophie Beaumont
- Sorin Buga
- Stephanie Trager
- Stephanie van Leeuwen
- Stephen Bernard
- Stephen Rajan Samuel
- Stephen Sonis
- Steven Gilbert
- Steven Roser
- Stuart Taylor
- Suranjan Maitra
- Susanne Skulski
- Suzanne Carlisle
- Sylvie Louise Avon
- Tabata Santos Polvora
- Tabitha Kelock
- Tais de Moraes
- Takashi Yurikusa
- Takehiko Mori
- Tauana Fernandes
- Taylor Wain
- Tetsuhito konishi
- Thalyta Amanda Ferreira
- Thomas Kelly
- Timothy Brown
- Tomoko Higuchi
- Tomoko Kataoka
- Tomoya Yokota
- Toshiaki Saeki
- Tsai-Wei Huang
- Typhaine Maupoint De Vandeul
- Vanessa Lacerda
- Vanessa Tilly
- Vasiliy Shchitka
- Verônica Serrano
- Victoria McCarvell
- Vinicius Torregrossa
- Vinodh Kumar Selvaraj
- Viola Salvestrini
- Viviane Sarmento
- Vivien Heng
- Wagner Gomes-Silva
- Wan Nor I'zzah Wan Mohamad Zain
- Wanessa Miranda e Silva
- Wilber Bernaola-Paredes
- Wim Tissing
- Wonse Park
- Yehuda Zadik
- Yehuda Zadik
- Yin Ting Cheung
- Ying Chu Choi
- Yoshihiko Soga
- Ysabella Van Sebille
- Yuhei Matsuda
- Yuji Kabasawa
- Publication venue
- Elsevier
- Publication date
- 01/07/2024
- Field of study
Summary: Background: Mucositis is a common and highly impactful side effect of conventional and emerging cancer therapy and thus the subject of intense investigation. Although common practice, mucositis assessment is heterogeneously adopted and poorly guided, impacting evidence synthesis and translation. The Multinational Association of Supportive Care in Cancer (MASCC) Mucositis Study Group (MSG) therefore aimed to establish expert recommendations for how existing mucositis assessment tools should be used, in clinical care and trials contexts, to improve the consistency of mucositis assessment. Methods: This study was conducted over two stages (January 2022–July 2023). The first phase involved a survey to MASCC-MSG members (January 2022–May 2022), capturing current practices, challenges and preferences. These then informed the second phase, in which a set of initial recommendations were prepared and refined using the Delphi method (February 2023–May 2023). Consensus was defined as agreement on a parameter by >80% of respondents. Findings: Seventy-two MASCC-MSG members completed the first phase of the study (37 females, 34 males, mainly oral care specialists). High variability was noted in the use of mucositis assessment tools, with a high reliance on clinician assessment compared to patient reported outcome measures (PROMs, 47% vs 3%, 37% used a combination). The World Health Organization (WHO) and Common Terminology Criteria for Adverse Events (CTCAE) scales were most commonly used to assess mucositis across multiple settings. Initial recommendations were reviewed by experienced MSG members and following two rounds of Delphi survey consensus was achieved in 91 of 100 recommendations. For example, in patients receiving chemotherapy, the recommended tool for clinician assessment in clinical practice is WHO for oral mucositis (89.5% consensus), and WHO or CTCAE for gastrointestinal mucositis (85.7% consensus). The recommended PROM in clinical trials is OMD/WQ for oral mucositis (93.3% consensus), and PRO-CTCAE for gastrointestinal mucositis (83.3% consensus). Interpretation: These new recommendations provide much needed guidance on mucositis assessment and may be applied in both clinical practice and research to streamline comparison and synthesis of global data sets, thus accelerating translation of new knowledge into clinical practice. Funding: No funding was received
Prospective observational cohort study on grading the severity of postoperative complications in global surgery research
- Author
- Abayasinghe Chamika
- Abbas Muntadhar
- Abbott T. E. F.
- Abbott Tom
- Abdullah Noor Hairiza
- Abdur-Rahman Lukman
- Abeloos Jacques
- Abernethy Caroline
- Abidin Ucu Nurhadiat
- Abrunhosa Alexandra
- Absar Mohammed
- Adam Suwayba
- Adams George
- Adamson Michael
- Adekola Oyebola
- Adelaja Yemi
- Ademola Adeyinka
- Adenekan Anthony
- Adenike Odewabi
- Adeolu Augustine A
- Adetoye Adedapo
- Adewale Badru
- Adigun Tinuola
- Adolfsson Anne
- Aflori Laura
- Africander Cucu
- Afshari Arash
- Agarwal Vandana
- Agodirin Olayide
- Aguzzoli Crisitiano
- Ahmad Abdurrahman
- Ahmad Norfaizan
- Ahmad T.
- Ahmad Tahania
- Ahmad Yousra
- Ahmed Ahmed
- Ahmed Jamil
- Ahmed Tahania
- Ai Yanqiu
- Aignatoaie Mariana
- Aimoniotou-Georgiou Eleni
- Akanmu Olanrewaju
- Akerman Nik
- Akinwale Mukaila
- Al Amri Khalid
- Al Hussaini Sabah
- Al-Soudaine Yassr
- Aladin Hafiz
- Alagbe-Briggs Olubusola
- Albaj Safauldeensalem
- Alcock David
- Alcock Liam
- Aldecoa Cesar
- Aldecoa Cesar
- Aleixo Fábia Berganton
- Alexander Hazel
- Alexander Maini
- Alexander-Sefre Farhad
- Alherz Fadhel
- Ali Hani
- Ali Marlynn
- Ali Sarah
- Alias Abdul Hafiz
- Alias Anita
- Alias Raja Liza Raja
- Allen Samantha
- Allen Sara Jane
- Allison Joanna
- Alloj Chiara
- Allorto Nikki Leigh
- Allsop Joanne
- Almeida William
- Alonso Eduardo
- Alonso José Ignacio
- Alphonsus Christella
- Alvares Danielle
- Alves Maria Joao
- Amador Juan Carlos Bravo
- Ameer Yusuf
- Amendola Cristina Prata
- Ami Noam
- Amstrup-Hansen Louise
- Anagnou Athina
- Andersen Cheme
- Anderson Charlotte
- Anderson Colette
- Anderson Frank
- Anderson Philip
- Andreadaki Evangelia
- Andreou Alexandros
- Andreou Prematie
- Andrew Alyson
- Andrews Emma
- Angel Miguel Paludi
- Angermair Stefan
- Angus Kirsty
- Anillo Victor
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- Antoniadou Eleni
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- Applewhaite Christopher
- Applewhaite Christopher
- Aquino Laura Patricia González
- Ar Praburaj
- Araujo Daniela Marques
- Arawwawala Dilshan
- Ardern Diane
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- Aribawa Mahaalit Alit
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- Arnaoutoglou Christina
- Arnaoutoglou Elena
- Arnold Glenn
- Arrandale Lindsay
- Arrich James
- Arrigo Mario
- Arshad Homa
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- Artiles Tania Socorro
- Arumugam Swarna
- Arustei Mirela
- Arvaniti Kostoula
- Arvaniti Kostoula
- Arya Aryabiantara
- Arya Shobhit
- Asimakos Andreas
- Aslam M
- Asudo Felicia
- Athanasakis Elias
- Atiku Mamuda
- Attrill Elizabeth
- Attwood Clare
- Auer Patrick
- Avidan Michael
- Avila Erendira Jocelin Dominguez
- Avis Joanne
- Awad Hadi
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- Azam Ummi Azmira Ahmad
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- Azevedo Caroline
- Aziz Faizal Zuhri
- Baas Peter
- Baghirzada Leyla
- Bai Hui-Ping
- Baillie Shelley
- Baines Duncan
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- Bairaktari Aggeliki
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- Balain Birender
- Balajonda Naraida
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- Banerjee Robin
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- Bateman Brian
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- Ganter Michael T
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- Gray Sophie
- Greaves K. E.
- Greaves Rosanna
- Green Garyth M
- Green-Thompson Randolph
- Greene Michael
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- Grigoras Ioana
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- Grubmueller Karl Gernot
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- Haddow James
- Hadebe Bernard
- Hadfield Daniel
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- Hamzah Zulkarnain
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- Hartmann Cristina
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- Hellstrom Johanna
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- Hennings Charles
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- Hernandez Miguel
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- Hidayatullah Rahmat
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- Hinxman Honor
- Hitchcock Rachael
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- Hobrok Maria
- Hodgkiss Tracey
- Hodgson Richard E
- Hodzovic Emil
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- Hu Liu
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- Hu Xianwen
- Hu Xiaolan
- Hu Xuming
- Huang Changshun
- Huang Ledan
- Huang Lixia
- Huang Luping
- Huang Song
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- Zhang Yuan
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- Zhao Bo
- Zhao Chong
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- Zhao Lei
- Zhao Shuna
- Zhao Ting
- Zhao Weihong
- Zhao Weilu
- Zhao Xiaoying
- Zhen Jungang
- Zheng Kang
- Zheng Lina
- Zheng Tianzhao
- Zhong Yi
- Zhou Ce
- Zhou Dachun
- Zhou Haidong
- Zhou Haiyan
- Zhou Jiali
- Zhou Jialong
- Zhou Jing
- Zhou Xian-jin
- Zhu Xiaomao
- Zhu Yi
- Zhu Zhipeng
- Zhuang Xiuxiu
- Zilis Georgios
- Zin Nor Hafizah Mohd
- Zingerle Nicolette
- Zingg Urs
- Zoerner Frank
- Zonneveldt Harry
- Zou Xiaohua
- Zoulamoglou Menelaos
- Zsisku Lajos
- Zundert Tom
- Zyl Rebekka
- åkring Irene
- Ögren Katrin
- Publication venue
- 'Wiley'
- Publication date
- 22/10/2018
- Field of study
Background
The Clavien–Dindo classification is perhaps the most widely used approach for reporting postoperative complications in clinical trials. This system classifies complication severity by the treatment provided. However, it is unclear whether the Clavien–Dindo system can be used internationally in studies across differing healthcare systems in high- (HICs) and low- and middle-income countries (LMICs).
Methods
This was a secondary analysis of the International Surgical Outcomes Study (ISOS), a prospective observational cohort study of elective surgery in adults. Data collection occurred over a 7-day period. Severity of complications was graded using Clavien–Dindo and the simpler ISOS grading (mild, moderate or severe, based on guided investigator judgement). Severity grading was compared using the intraclass correlation coefficient (ICC). Data are presented as frequencies and ICC values (with 95 per cent c.i.). The analysis was stratified by income status of the country, comparing HICs with LMICs.
Results
A total of 44 814 patients were recruited from 474 hospitals in 27 countries (19 HICs and 8 LMICs). Some 7508 patients (16·8 per cent) experienced at least one postoperative complication, equivalent to 11 664 complications in total. Using the ISOS classification, 5504 of 11 664 complications (47·2 per cent) were graded as mild, 4244 (36·4 per cent) as moderate and 1916 (16·4 per cent) as severe. Using Clavien–Dindo, 6781 of 11 664 complications (58·1 per cent) were graded as I or II, 1740 (14·9 per cent) as III, 2408 (20·6 per cent) as IV and 735 (6·3 per cent) as V. Agreement between classification systems was poor overall (ICC 0·41, 95 per cent c.i. 0·20 to 0·55), and in LMICs (ICC 0·23, 0·05 to 0·38) and HICs (ICC 0·46, 0·25 to 0·59).
Conclusion
Caution is recommended when using a treatment approach to grade complications in global surgery studies, as this may introduce bias unintentionally