La socialización de la producción científica desde la gestión del conocimiento

The objective of this article is to base the socialization of the scientific production, its access, visibility and recognition, by means of actions of management of the knowledge for its introduction and generalization in the educational practice, in the context of Pedagogical Science University “Enrique J. Varona, Havana, Cuba. It was carried out a bibliographical revision that allowed the systematizing of roads, tools, scenarios that facilitate the socialization of the results of the scientific educational activity exposed in the scientific production

La socialización de la producción científica desde la gestión del conocimiento

The objective of this article is to base the socialization of the scientific production, its access, visibility and recognition, by means of actions of management of the knowledge for its introduction and generalization in the educational practice, in the context of Pedagogical Science University “Enrique J. Varona, Havana, Cuba. It was carried out a bibliographical revision that allowed the systematizing of roads, tools, scenarios that facilitate the socialization of the results of the scientific educational activity exposed in the scientific production

Campesinos sin resolución agraria: la difícil construcción de la gobernanza ambiental en un área natural protegida de Chiapas, México

Throughout the years, protected natural areas have been gaining increasing importance as a tool through which international organizations can preserve ecosystems. However, some of these protected areas are often established in previously inhabited territories. This study addresses the implications of the decree creating the Biosphere Reserve La Sepultura, above of Los Laureles. Using a diachronic qualitative methodology applied to a case study and life histories, it was found that the area’s lag in agricultural development together with the preservation decree led the agricultural and environmental authorities to classify this location as an irregular settlement. For this reason, government programs were cancelled and conflicts emerged between inhabitants. These factors had a determining influence on the agricultural, social and economic-productive dynamics since they pushed the population towards marginalization and exclusion. These groups, in their struggle to remain in their territory act above all in agreement with the environmental governance issuing from the decree defining their territory as a Protected Natural Area.Las áreas naturales protegidas como instrumentos de conservación de los ecosistemas han ido cobrando mayor importancia ante los organismos internacionales; sin embargo, varias de estas zonas de protección son frecuentemente establecidas sobre territorios ya habitados. Este artículo aborda las implicaciones del decreto de la Reserva de la Biosfera La Sepultura sobre la localidad de Los Laureles. Mediante la metodología cualitativa diacrónica en un estudio de caso y de historias de vida se encontró que el rezago agrario, aunado al decreto de conservación, provocó que dicho poblado fuera catalogado por las autoridades agrarias y ambientales como asentamiento irregular, situación que ocasionó la cancelación de programas gubernamentales y el surgimiento de conflictos entre sus pobladores; estos factores determinaron las dinámicas agraria, social y económico-productiva al propiciar procesos de marginación y exclusión entre los pobladores de la localidad, cuya lucha por permanecer en el territorio involucra sobre todo atender la gobernanza ambiental que emanó del decreto del área natural protegida

Campesinos sin resolución agraria: la difícil construcción de la gobernanza ambiental en un área natural protegida de Chiapas, México

Las áreas naturales protegidas como instrumentos de conservación de los ecosistemas han ido cobrando mayor importancia ante los organismos internacionales; sin embargo, varias de estas zonas de protección son frecuentemente establecidas sobre territorios ya habitados. Este artículo aborda las implicaciones del decreto de la Reserva de la Biosfera La Sepultura sobre la localidad de Los Laureles. Mediante la metodología cualitativa diacrónica en un estudio de caso y de historias de vida se encontró que el rezago agrario, aunado al decreto de conservación, provocó que dicho poblado fuera catalogado por las autoridades agrarias y ambientales como asentamiento irregular, situación que ocasionó la cancelación de programas gubernamentales y el surgimiento de conflictos entre sus pobladores; estos factores determinaron las dinámicas agraria, social y económico-productiva al propiciar procesos de marginación y exclusión entre los pobladores de la localidad, cuya lucha por permanecer en el territorio involucra sobre todo atender la gobernanza ambiental que emanó del decreto del área natural protegida

Activación de la inteligencia emocional en los estudiantes universitarios de Grado en Educación a través de un programa de intervención de competencia emocional en el aula

Depto. de Investigación y Psicología en EducaciónFac. de EducaciónFALSEsubmitte

Human and mouse seeds differentially affect AB aggregation by modulating the inflammatory response.

Abstract text: Alzheimer’s Disease (AD) is a neurodegenerative proteinopathy in which Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prionlike process. These amyloid aggregation and propagation processes are influenced by three factors: the origin of the Aβ seed, time of incubation and host. However, the mechanism underlying the differential effect of each factor is poorly known. Previous studies have shown that the Aβ source is relevant for the amyloid process, since its pathogenicity is different according to its origin. Furthermore, recent evidence suggests that microglia plays a key role in the amyloidogenic event, and can modulate the propagation and aggregation process. Here, we seek to perform a comparative study to determine whether Aβ seeds from humans vs a familial AD line (the 3xTg-AD model) are more efficient to generate amyloid aggregates, as well as the role of the microglia in the propagation process. Methods: Amyloid seeds from AD patient (stage C for amyloid; from the Alzheimer’s Disease Research Center at UCI) and 25 mo-3xTg-AD mice were injected into the hippocampus of 7-8- month-old 3xTg-AD mice. They were analyzed 10 months post-surgery for amyloid and microglia markers. Results: Our findings demonstrated that amyloid seeds from the human patient seem to induce a more aggressive amyloid pathology compared to seeds from aged 3xTg-AD mice. Moreover, human and mice seeds differentially affect the presence of plaque-associated microglia in 3xTgAD mice. Conclusion: These results suggest that seeds from human patients seem to be more amyloidogenic than from aged 3xTg-AD mice, and also microglia cells may play a key role in this differential effect. Therefore, more profound understanding these factors will provide key insight on how amyloid pathology progresses in AD.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

El perfil de salud-enfermedad bucal y las necesidades de tratamiento de los adultos mayores de Lima urbana 2012

The main objective of this study was to determine the profile of oral health and disease of the elderly adults of urban Lima, taking into account the prevalence of dental caries, periodontal disease, oral mucosa injuries and treatment needs. Descriptive and transversal study was using over 120 elderly adults (over 60 years old), living in Lima center and district. Data collection was performed by the method of clinical observation and interview using rates and procedures of the WHO. The results obtained were: average age 71 years, high prevalence of the female gender (70%) and secondary education, presence of hypertension with 33 % and diabetes mellitus with 10.8%, the mucosal disorders in 10.8 %, with ulceration type localized on the palate and alveolar ridges. Also was observed presence of calculi and periodontal bleeding in 52% of the population. The study subjects requiring prophylaxis in 23.3 % and needed just a case of root planing in 11%. Teeth present in the mouth, the 23% have lost fixation at 4-5 mm. Only 5.82 % of the teeth are healthy, with an average of 4.43 cavities, missing teeth 14.77 with 53%. The DMF had a mean of 19.71 with a Ds . 6.74. The 31.7 % use removable full dentures and fixed prostheses by 19.2 %. In the lower jaw using PPR with 20% and 13.3 % use full dentures and fixed prostheses with 9.27%. Finding a high need for the use of removable dentures in upper and lower jaw. It was determined that the oral health of older people is poor due to the poor hygiene, introduction of caries and periodontal disease and in dire need of restoration of cavities, use of removable, removable total and fixed partial denture.El objetivo principal de este estudio fue determinar el perfil de salud- enfermedad bucal de las personas adultos mayores (AM) de Lima urbana, tomando en cuenta la prevalencia de caries dental, enfermedad periodontal, lesiones mucosa bucal y necesidades de tratamiento. Se realizó un estudio de tipo descriptivo-trasversal en 120 personas adultas mayores de 60 años, que viven en Lima cercado y distritos. La recolección de datos se realizó a través del método de observación clínica y entrevista haciendo uso de los índices y procedimientos de la OMS. Los resultados obtenidos fueron: edad promedio 71 años, con prevalencia del sexo femenino (70%) y educación secundaria, presencia de hipertensión arterial 33% y diabetes miellitus 10.8 %, trastornos de la mucosa en un 10.8%, siendo del tipo ulceración localizadas en el paladar y rebordes alveolares. Presencia de cálculos y sangrado periodontal, en el 52% de la población. El 23.3% necesita profilaxis y solo un 11% raspaje radicular. De los dientes presentes en boca el 23% han perdido fijación en 4-5 mm. Solo 5.82% de los dientes se encuentran sanos, siendo el promedio de caries 4.43, dientes perdidos 14,77 del 53%. El CPO tuvo una media de 19.71. Ds. 6.74. El 31.7% usan prótesis total removible superior y prótesis fija en un 19,2%. En el maxilar inferior un 20% utilizan PPR y el 13,3% usan prótesis total y fija 9,27%. Encontrándose una alta necesidad de prótesis removible en maxilar superior e inferior. Se logró determinar que la salud bucal de las personas adultas mayores es mala por efecto de la caries y enfermedad periodontal y con gran necesidad de higiene, operatoria y prótesis parcial removible, removibles totales y fijas

Usos del e‐learning en las Universidades Andaluzas: estado de la situación y análisis de buenas prácticas. (Resumen ejecutivo).

Secretaría General de Universidades, Investigación y Tecnología P07-SE-J.0267

Usos del e-learning en las Universidades Andaluzas: Estado de la situación y análisis de buenas prácticas. (Versión completa)

Secretaría General de Universidades, Investigación y Tecnología P07-SE-J.0267

Effectiveness of an intervention for improving drug prescription in primary care patients with multimorbidity and polypharmacy:Study protocol of a cluster randomized clinical trial (Multi-PAP project)

This study was funded by the Fondo de Investigaciones Sanitarias ISCIII (Grant Numbers PI15/00276, PI15/00572, PI15/00996), REDISSEC (Project Numbers RD12/0001/0012, RD16/0001/0005), and the European Regional Development Fund ("A way to build Europe").Background: Multimorbidity is associated with negative effects both on people's health and on healthcare systems. A key problem linked to multimorbidity is polypharmacy, which in turn is associated with increased risk of partly preventable adverse effects, including mortality. The Ariadne principles describe a model of care based on a thorough assessment of diseases, treatments (and potential interactions), clinical status, context and preferences of patients with multimorbidity, with the aim of prioritizing and sharing realistic treatment goals that guide an individualized management. The aim of this study is to evaluate the effectiveness of a complex intervention that implements the Ariadne principles in a population of young-old patients with multimorbidity and polypharmacy. The intervention seeks to improve the appropriateness of prescribing in primary care (PC), as measured by the medication appropriateness index (MAI) score at 6 and 12months, as compared with usual care. Methods/Design: Design:pragmatic cluster randomized clinical trial. Unit of randomization: family physician (FP). Unit of analysis: patient. Scope: PC health centres in three autonomous communities: Aragon, Madrid, and Andalusia (Spain). Population: patients aged 65-74years with multimorbidity (≥3 chronic diseases) and polypharmacy (≥5 drugs prescribed in ≥3months). Sample size: n=400 (200 per study arm). Intervention: complex intervention based on the implementation of the Ariadne principles with two components: (1) FP training and (2) FP-patient interview. Outcomes: MAI score, health services use, quality of life (Euroqol 5D-5L), pharmacotherapy and adherence to treatment (Morisky-Green, Haynes-Sackett), and clinical and socio-demographic variables. Statistical analysis: primary outcome is the difference in MAI score between T0 and T1 and corresponding 95% confidence interval. Adjustment for confounding factors will be performed by multilevel analysis. All analyses will be carried out in accordance with the intention-to-treat principle. Discussion: It is essential to provide evidence concerning interventions on PC patients with polypharmacy and multimorbidity, conducted in the context of routine clinical practice, and involving young-old patients with significant potential for preventing negative health outcomes. Trial registration: Clinicaltrials.gov, NCT02866799Publisher PDFPeer reviewe