Sanguinet – Le Lac

Identifiant de l'opération archéologique : 025099 Date de l'opération : 2007 (PT) La vallée de la Gourgue prospectée entre 2001 et 2005 entre les sites de l’Estey du large et de Put Blanc a amené la découverte de zones d’habitat liées chronologiquement à ces deux espaces archéologiques. Ainsi sur une distance de près d’un kilomètre, nous avons affaire à une occupation humaine qui recouvre la totalité de l’âge du Fer. Pour compléter la connaissance du peuplement de la vallée ennoyée, nous avon..

Sanguinet – Le Lac

Identifiant de l'opération archéologique : 025348 Date de l'opération : 2008 (PT) La prospection de la rive gauche de la vallée de la Gourgue s’est poursuivie cette année dans la bande C de 20 000 m2, située immédiatement au nord des bandes A et B visitées précédemment. Cette zone se rapproche du lit de la rivière antique et les profondeurs s’échelonnent entre 12 m et 16 m. Sites de Matocq et de Put Blanc Sur ce vaste espace prospecté depuis 2006, de nombreux vestiges anthropiques ont été mis..

Design and analysis of a foldable / unfoldable corrugated architectural curved envelop

11 pagesInternational audienceOrigami and paperfolding techniques may inspire the design of structures that have the ability to be folded and unfolded: their geometry can be changed from an extended, servicing state to a compact one, and back-forth. In traditional Origami, folds are introduced in a sheet of paper (a developable surface) for transforming its shape, with artistic or decorative intent; in recent times the ideas behind origami techniques were transferred in various design disciplines to build developable foldable / unfoldable structures, mostly in aerospace industry. The geometrical arrangement of folds allows a folding mechanism of great efficiency and is often derived from the buckling patterns of simple geometries, like a plane or a cylinder (e.g. Miura-Ori and Yoshimura folding pattern). Here we interest ourselves to the conception of foldable / unfoldable structures for civil engineering and architecture. In those disciplines, the need for folding efficiency comes along with the need for structural efficiency (stiffness); for this purpose we will explore nondevelopable foldable / unfoldable structures: those structures exhibit potential stiffness because, when unfolded, they cannot be flattened to a plane (non-developability). In this paper we propose a classification for foldable / unfoldable surfaces that comprehend non fully developable (and also non fully foldable) surfaces and a method for the description of folding motion. Then we propose innovative geometrical configurations for those structures by generalizing the Miura-Ori folding pattern to non-developable surfaces that, once unfolded, exhibit curvature

TeV cosmic-ray proton and helium spectra in the myriad model

Recent measurements of cosmic ray proton and helium spectra show a hardening above a few hundreds of GeV. This excess is hard to understand in the framework of the conventional models of Galactic cosmic ray production and propagation. We propose here to explain this anomaly by the presence of local sources (myriad model). Cosmic ray propagation is described as a diffusion process taking place inside a two-zone magnetic halo. We calculate the proton and helium fluxes at the Earth between 50 GeV and 100 TeV. Improving over a similar analysis, we consistently derive these fluxes by taking into account both local and remote sources for which a unique injection rate is assumed. We find cosmic ray propagation parameters compatible with B/C measurements and for which the proton and helium spectra remarkably agree with the PAMELA and CREAM measurements over four decades in energy.Comment: 5 pages, 3 figure

Comparison of absolute gain photometric calibration between Planck/HFI and Herschel/SPIRE at 545 and 857 GHz

We compare the absolute gain photometric calibration of the Planck/HFI and Herschel/SPIRE instruments on diffuse emission. The absolute calibration of HFI and SPIRE each relies on planet flux measurements and comparison with theoretical far-infrared emission models of planetary atmospheres. We measure the photometric cross calibration between the instruments at two overlapping bands, 545 GHz / 500 $\mu$m and 857 GHz / 350 $\mu$m. The SPIRE maps used have been processed in the Herschel Interactive Processing Environment (Version 12) and the HFI data are from the 2015 Public Data Release 2. For our study we used 15 large fields observed with SPIRE, which cover a total of about 120 deg^2. We have selected these fields carefully to provide high signal-to-noise ratio, avoid residual systematics in the SPIRE maps, and span a wide range of surface brightness. The HFI maps are bandpass-corrected to match the emission observed by the SPIRE bandpasses. The SPIRE maps are convolved to match the HFI beam and put on a common pixel grid. We measure the cross-calibration relative gain between the instruments using two methods in each field, pixel-to-pixel correlation and angular power spectrum measurements. The SPIRE / HFI relative gains are 1.047 ($\pm$ 0.0069) and 1.003 ($\pm$ 0.0080) at 545 and 857 GHz, respectively, indicating very good agreement between the instruments. These relative gains deviate from unity by much less than the uncertainty of the absolute extended emission calibration, which is about 6.4% and 9.5% for HFI and SPIRE, respectively, but the deviations are comparable to the values 1.4% and 5.5% for HFI and SPIRE if the uncertainty from models of the common calibrator can be discounted. Of the 5.5% uncertainty for SPIRE, 4% arises from the uncertainty of the effective beam solid angle, which impacts the adopted SPIRE point source to extended source unit conversion factor (Abridged)Comment: 13 pages, 10 figures; Incorporates revisions in response to referee comments; cross calibration factors unchange

Real-Time PCR for Diagnosis of Oculoglandular Tularemia

International audienc

Gut microbiota analysis reveals a marked shift to bifidobacteria by a starter infant formula containing a synbiotic of bovine milk-derived oligosaccharides and Bifidobacterium animalis subsp. lactis CNCM I-3446.

Non-digestible milk oligosaccharides were proposed as receptor decoys for pathogens and as nutrients for beneficial gut commensals like bifidobacteria. Bovine milk contains oligosaccharides, some of which are structurally identical or similar to those found in human milk. In a controlled, randomized double-blinded clinical trial we tested the effect of feeding a formula supplemented with a mixture of bovine milk-derived oligosaccharides (BMOS) generated from whey permeate, containing galacto-oligosaccharides and 3'- and 6'-sialyllactose, and the probiotic Bifidobacterium animalis subsp. lactis (B. lactis) strain CNCM I-3446. Breastfed infants served as reference group. Compared with a non-supplemented control formula, the test formula showed a similar tolerability and supported a similar growth in healthy newborns followed for 12 weeks. The control, but not the test group, differed from the breast-fed reference group by a higher faecal pH and a significantly higher diversity of the faecal microbiota. In the test group the probiotic B. lactis increased by 100-fold in the stool and was detected in all supplemented infants. BMOS stimulated a marked shift to a bifidobacterium-dominated faecal microbiota via increases in endogenous bifidobacteria (B. longum, B. breve, B. bifidum, B. pseudocatenulatum)

Evidence of Transfer by Conjugation of Type IV Secretion System Genes between Bartonella Species and Rhizobium radiobacter in Amoeba

Background: Bartonella species cospeciate with mammals and live within erythrocytes. Even in these specific niches, it has been recently suggested by bioinformatic analysis of full genome sequences that Lateral Gene Transfer (LGT) may occur but this has never been demonstrated biologically. Here we describe the sequence of the B. rattaustraliani (AUST/NH4 T) circular plasmid (pNH4) that encodes the tra cluster of the Type IV secretion system (T4SS) and we eventually provide evidence that Bartonella species may conjugate and exchange this plasmid inside amoeba. Principal Findings: The T4SS of pNH4 is critical for intracellular viability of bacterial pathogens, exhibits bioinformatic evidence of LGT among bacteria living in phagocytic protists. For instance, 3 out of 4 T4SS encoding genes from pNH4 appear to be closely related to Rhizobiales, suggesting that gene exchange occurs between intracellular bacteria from mammals (bartonellae) and plants (Rhizobiales). We show that B. rattaustraliani and Rhizobium radiobacter both survived within the amoeba Acanthamoeba polyphaga and can conjugate together. Our findings further support the hypothesis that tra genes might also move into and out of bacterial communities by conjugation, which might be the primary means of genomic evolution for intracellular adaptation by cross-talk of interchangeable genes between Bartonella species and plant pathogens. Conclusions: Based on this, we speculate that amoeba favor the transfer of genes as phagocytic protists, which allows fo

Tularaemia: A challenging zoonosis

In recent years, several emerging zoonotic vector-borne infections with potential impact on human health have been identified in Europe, including tularaemia, caused by Francisella tularensis.This remarkable pathogen, one of the most virulent microorganisms currently known, has been detected in increasingly new settings and in a wide range of wild species, including lagomorphs, rodents, carnivores, fish and invertebrate arthropods. Also, a renewed concern has arisen with regard to F. tularensis: its potential use by bioterrorists. Based on the information published concerning the latest outbreaks, the aim of this paper is to review the main features of the agent, its biology, immunology and epidemiology. Moreover, special focus will be given to zoonotic aspects of the disease, as tularaemia outbreaks in human populations have been frequently associated with disease in animals