559 research outputs found

    Graphene–Metamaterial Photodetectors for Integrated Infrared Sensing

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    PublishedIn this work we study metamaterial-enhanced graphene photodetectors operating in the mid-IR to THz. The detector element consists of a graphene ribbon embedded within a dual-metal split ring resonator, which acts like a cavity to enhance the absorption of electromagnetic radiation by the graphene ribbon, while the asymmetric metal contacts enable photothermoelectric detection. Detectors designed for the mid-IR demonstrate peak responsivity (referenced to total power) of ∼120 mV/W at 1500 cm–1 and are employed in the spectroscopic evaluation of vibrational resonances, thus demonstrating a key step toward a platform for integrated surface-enhanced sensing.The authors thank Johanna Wolf for providing the QCL used for the detector characterization. This research was supported by the European Union under the FET-open grant GOSFEL and the Swiss National Science Foundation through NCCR QSIT. G.R.N. also gratefully acknowledges the support of the UK Engineering and Physical Sciences Research Council through a fellowship in Frontier Manufacturing (Grant No. EP/J018651/1)

    Strong coupling in the far-infrared between graphene plasmons and the surface optical phonons of silicon dioxide

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    This is the author accepted manuscript. The final version is available from American Chemical Society via the DOI in this record.We study plasmonic resonances in electrostatically gated graphene nanoribbons on silicon dioxide substrates. Absorption spectra are measured in the mid-far infrared and reveal multiple peaks, with width-dependent resonant frequencies. We calculate the dielectric function within the random phase approximation and show that the observed spectra can be explained by surface-plasmon-phonon-polariton modes, which arise from coupling of the graphene plasmon to three surface optical phonon modes in the silicon dioxide.This research was supported by the UK Engineering and Physical Sciences Research Council, via the award of a Fellowship in Frontier Manufacturing (EP/J018651/1) to G.N., and the European Union under the FET-open grant GOSFEL

    Digenean parasites of Chinese marine fishes: a list of species, hosts and geographical distribution

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    In the literature, 630 species of Digenea (Trematoda) have been reported from Chinese marine fishes. These belong to 209 genera and 35 families. The names of these species, along with their hosts, geographical distribution and records, are listed in this paper

    The Roles of Serum Selenium and Selenoproteins on Mercury Toxicity in Environmental and Occupational Exposure

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    Many studies have found that mercury (Hg) exposure is associated with selenium (Se) accumulation in vivo. However, human studies are limited. To study the interaction between Se and Hg, we investigated the total Se and Hg concentrations in body fluids and serum Se-containing proteins in individuals exposed to high concentrations of Hg. Our objective was to elucidate the possible roles of serum Se and selenoproteins in transporting and binding Hg in human populations. We collected data from 72 subjects: 35 had very low Hg exposure as evidenced by mean Hg concentrations of 0.91 and 1.25 ng/mL measured in serum and urine, respectively; 37 had high exposure (mean Hg concentrations of 38.5 and 86.8 ng/mL measured in serum and urine, respectively). An association between Se and Hg was found in urine (r = 0.625; p < 0.001) but not in serum. Hg exposure may affect Se concentrations and selenoprotein distribution in human serum. Expression of both selenoprotein P and glutathione peroxidase (GSH-Px) was greatly increased in Hg miners. These increases were accompanied by elevated Se concentrations in serum. In addition, selenoprotein P bound more Hg at higher Hg exposure concentrations. Biochemical observations revealed that both GSH-Px activity and malondialdehyde concentrations increased in serum of the Hg-exposed group. This study aids in the understanding of the interaction between Se and Hg. Selenoproteins play two important roles in protecting against Hg toxicity. First, they may bind more Hg through their highly reactive selenol group, and second, their antioxidative properties help eliminate the reactive oxygen species induced by Hg in vivo

    Ring-LWE:applications to cryptography and their efficient realization

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    © Springer International Publishing AG 2016. The persistent progress of quantum computing with algorithms of Shor and Proos and Zalka has put our present RSA and ECC based public key cryptosystems at peril. There is a flurry of activity in cryptographic research community to replace classical cryptography schemes with their post-quantum counterparts. The learning with errors problem introduced by Oded Regev offers a way to design secure cryptography schemes in the post-quantum world. Later for efficiency LWE was adapted for ring polynomials known as Ring-LWE. In this paper we discuss some of these ring-LWE based schemes that have been designed. We have also drawn comparisons of different implementations of those schemes to illustrate their evolution from theoretical proposals to practically feasible schemes

    Improved Progressive BKZ Algorithms and their Precise Cost Estimation by Sharp Simulator

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    In this paper, we investigate a variant of the BKZ algorithm, called progressive BKZ, which performs BKZ reductions by starting with a small blocksize and gradually switching to larger blocks as the process continues. We discuss techniques to accelerate the speed of the progressive BKZ algorithm by optimizing the following parameters: blocksize, searching radius and probability for pruning of the local enumeration algorithm, and the constant in the geometric series assumption (GSA). We then propose a simulator for predicting the length of the Gram-Schmidt basis obtained from the BKZ reduction. We also present a model for estimating the computational cost of the proposed progressive BKZ by considering the efficient implementation of the local enumeration algorithm and the LLL algorithm. Finally, we compare the cost of the proposed progressive BKZ with that of other algorithms using instances from the Darmstadt SVP Challenge. The proposed algorithm is approximately 50 times faster than BKZ 2.0 (proposed by Chen-Nguyen) for solving the SVP Challenge up to 160 dimensions

    A New Microsphere-Based Immunoassay for Measuring the Activity of Transcription Factors

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    There are several traditional and well-developed methods for analyzing the activity of transcription factors, such as EMSA, enzyme-linked immunosorbent assay, and reporter gene activity assays. All of these methods have their own distinct disadvantages, but none can analyze the changes in transcription factors in the few cells that are cultured in the wells of 96-well titer plates. Thus, a new microsphere-based immunoassay to measure the activity of transcription factors (MIA-TF) was developed. In MIA-TF, NeutrAvidin-labeled microspheres were used as the solid phase to capture biotin-labeled double-strand DNA fragments which contain certain transcription factor binding elements. The activity of transcription factors was detected by immunoassay using a transcription factor-specific antibody to monitor the binding with the DNA probe. Next, analysis was performed by flow cytometry. The targets hypoxia-inducible factor-1α (HIF-1α) and nuclear factor-kappa B (NF-κB) were applied and detected in this MIA-TF method; the results that we obtained demonstrated that this method could be used to monitor the changes of NF-κB or HIF within 50 or 100 ng of nuclear extract. Furthermore, MIA-TF could detect the changes in NF-κB or HIF in cells that were cultured in wells of a 96-well plate without purification of the nuclear protein, an important consideration for applying this method to high-throughput assays in the future. The development of MIA-TF would support further progress in clinical analysis and drug screening systems. Overall, MIA-TF is a method with high potential to detect the activity of transcription factors

    The General Sieve Kernel and New Records in Lattice Reduction

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    textabstractWe propose the General Sieve Kernel (G6K, pronounced /Ze.si.ka/), an abstract stateful machine supporting a wide variety of lattice reduction strategies based on sieving algorithms. Using the basic instruction set of this abstract stateful machine, we first give concise formulations of previous sieving strategies from the literature and then propose new ones. We then also give a light variant of BKZ exploiting the features of our abstract stateful machine. This encapsulates several recent suggestions (Ducas at Eurocrypt 2018; Laarhoven and Mariano at PQCrypto 2018) to move beyond treating sieving as a blackbox SVP oracle and to utilise strong lattice reduction as preprocessing for sieving. Furthermore, we propose new tricks to minimise the sieving computation required for a given reduction quality with mechanisms such as recycling vectors between sieves, on-the-fly lifting and flexible insertions akin to Deep LLL and recent variants of Random Sampling Reduction. Moreover, we provide a highly optimised, multi-threaded and tweakable implementation of this machine which we make open-source. We then illustrate the performance of this implementation of our sieving strategies by applying G6K to various lattice challenges. In particular, our approach allows us to solve previously unsolved instances of the Darmstadt SVP (151, 153, 155) and LWE (e.g. (75, 0.005)) challenges. Our solution for the SVP-151 challenge was found 400 times faster than the time reported for the SVP-150 challenge, the previous record. For exact SVP, we observe a performance crossover between G6K and FPLLL’s state of the art implementation of enumeration at dimension 70

    Precise measurement of the W-boson mass with the CDF II detector

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    We have measured the W-boson mass MW using data corresponding to 2.2/fb of integrated luminosity collected in proton-antiproton collisions at 1.96 TeV with the CDF II detector at the Fermilab Tevatron collider. Samples consisting of 470126 W->enu candidates and 624708 W->munu candidates yield the measurement MW = 80387 +- 12 (stat) +- 15 (syst) = 80387 +- 19 MeV. This is the most precise measurement of the W-boson mass to date and significantly exceeds the precision of all previous measurements combined
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