Gestión vial rural y seguridad vial en el Instituto Vial Provincial de San Martín – 2020

La investigación tuvo como objetivo determinar la relación de la Gestión vial rural y la seguridad vial en el Instituto Vial Provincial de San Martín - 2020. La investigación fue de tipo básica, transversal, de diseño no experimental y descriptivo correlacional. La muestra estuvo conformada por 50 personas que son parte de la organización paramunicipal. Se utilizó la técnica de la encuesta y se preparó dos cuestionarios estructurados y no estandarizados para el acopio de datos. Los resultados de la investigación demuestran que las dimensiones Capacidad institucional y Sostenibilidad financiera tienen relación significativa con la seguridad vial en el Instituto Vial Provincial de San Martín - 2020. Por otro lado, el 70.0% de consultados consideran que el nivel de la gestión vial rural del Instituto Vial Provincial de San Martin – 2020 es regular, y el 68.0 % refieren que el nivel de la seguridad vial en el Instituto Vial Provincial de San Martin –2020 es regular. La principal conclusión de la investigación evidencia que existe una relación positiva moderada (Rho de Spearman = 0.647) y es significativa en un nivel de 0.01

Applications de l'analyse en ondelettes sur un signal géophysique

Ce papier propose différentes techniques pour caractériser un signal géophysique à partir de la transformée en ondelettes continue et de l'analyse multirésolution. Tout d'abord, nous présentons des outils pour caractériser et extraire les structures ondulatoires dominantes du signal et ensuite trois méthodes originales pour déterminer la vitesse de phase verticale sur des signaux successifs. Le signal géophysique étudié pour illustrer ces méthodes est un signal LIDAR dont la structure thermique verticale de 30 à 60 km d'altitude au-dessus de la Réunion (21°S, 55°E) est déduite. Ces méthodes peuvent être étendues à d'autres domaines géophysiques ayant des signaux du même type : sonar, radar, réflectomètrie

Interdisciplinary characterisation and environmental imprints of mining and forestry in the upper Durance valley (France) during the Holocene

International audienceThe upper Durance valley contains the largest silverelead mines of the French Southern Alps. We investigated the characterisation and impact of these mining activities and associated forestry in the Argentière (L'Argentière-La Bessée) and Faravel (Freissinières) districts using a multidisciplinary approach that includes archaeological, palynological, geochemical, anthracological and dendrochrono-logical studies applied to mining remnants and a peat bog (Fangeas, in the Faravel district). More specifically , we studied the occurrence of lead contamination episodes, the chronology of mining activities and their link to the evolution in woodland cover. Our chronology is based on mining archaeology, radiocarbon dating of about thirty charcoal samples and the dendrochronological analysis of more than 170 specimens of exhumed waterlogged wood. The anthracological analysis was established with more than 10,000 charcoals from firesetting. The main geochemical approach was based on the analysis of lead and its stable isotopes in sediment fractions from a peat core. The combination of palynological records and lead isotope imprints were used to characterise (i) a Roman contamination episode unknown to archaeology, (ii) the development of medieval mining activities and (iii) the reactivation of mining during the Modern period and the Industrial Revolution. Medieval mining coincides with an extension of the high mountain agropastoral areas. The in situ continuous human activities in the same industrial territory led to rational communal management of subalpine forests, but also to their parcelling that reached its peak in the High Middle Ages. Mining during the Modern period coincides with significant stress on woodland areas that also appears to be related to lumber and fuel timber production for shipyards (French Royal Navy) as well as the functioning of several military fortresses. The mining reactivation during the 19th c. matched public measures of forest protection that took shape in the afforestation programme of the uplands

Fostering the Diversity of Exploratory Testing in Web Applications

International audienceExploratory testing (ET) is a software testing approach that complements automated testing by leveraging business expertise. It has gained momentum over the last decades as it appeals testers to exploit their business knowledge to stress the system under test (SUT). Exploratory tests, unlike automated tests, are defined and executed on-the-fly by testers.Testers who perform exploratory tests may be biased by their past experience and therefore may miss anomalies or unusual interactions proposed by the SUT. This is even more complex in the context of web applications, which typically expose a huge number of interaction paths to their users. As testers of these applications cannot remember all the sequences of interactions they performed, they may fail to deeply explore the application scope.This paper therefore introduces a new approach that assists testers in widely exploring any web application. In particular, our approach monitors the online interactions performed by the testers to suggest in real-time the probabilities of performing next interactions. Looking at these probabilities, we claim that the testers who favour interactions that have a low probability(because they were rarely performed), will increase the diversity of their explorations. Our approach defines a prediction model, based on n-grams, that encodes the history of past interactions and that supports the estimation of the probabilities. Integrated within a web browser extension, it automatically and transparently injects feedback within the application itself. We conduct a controlled experiment and a qualitative study to assess our approach. Results show that it prevents testers to be trapped in already tested loops, and succeeds to assist them in performing deeper explorations of the SUT

Tetratricopeptide repeat domain 7A is a nuclear factor that modulates transcription and chromatin structure

A loss-of-function mutation in tetratricopeptide repeat domain 7A (TTC7A) is a recently identified cause of human intestinal and immune disorders. However, clues to related underlying molecular dysfunctions remain elusive. It is now shown based on the study of TTC7A-deficient and wild-type cells that TTC7A is an essential nuclear protein. It binds to chromatin, preferentially at actively transcribed regions. Its depletion results in broad range of epigenomic changes at proximal and distal transcriptional regulatory elements and in altered control of the transcriptional program. Loss of WT_TTC7A induces general decrease in chromatin compaction, unbalanced cellular distribution of histones, higher nucleosome accessibility to nuclease digestion along with genome instability, and reduced cell viability. Our observations characterize for the first time unreported functions for TTC7A in the nucleus that exert a critical role in chromatin organization and gene regulation to safeguard healthy immune and intestinal status.</p

Modelo de um sistema eutrófico: fluxo dos nutrientes e sinecologia das populações planctônicas

Based on the information obtained from the Gulf of Fos, France, we propose herewith a generalized model to characterize the physical, chemical and biological parameters and their interrelationship in the eutrophic coastal system. This system is characterized by having high concentration of suspended materials, especially the mineral fraction (C/N >; 30). Nutrients concentrations are very high, except in diluted basins. The N-NO3/P-P04 ratio is usually low, due to the preferential assimilation of nitrates and the presence of polyphosphates from sewage waters. The concentrations of phaeopigments are always high (more than 50%), due to the mortalities of freshwater originated phytoplankton, the resuspension of dead vegetal materials, and the grazing of zooplankton. We noted in diluted water of eutrophic system the biomass is high, but the diversity is relatived low, among adapted cells with low " energetic charge". Whereas in oceanic water, the biomass is less, the diversity and energetic charge are increasing. This may indicate that phytoplankton communities have to make an effort to grow and duplicate. In comparing zooplankton populations from eutrophic to oligotrophic waters, biochemical diferentiations were observed for a same species, which may due to the difference in salinities and the presence of chemical pollutants

La sculpture romaine en Occident

Cet ouvrage réunit les résultats de deux manifestations complémentaires  : d’une part, la table ronde intitulée «  Rendre à César  », organisée le mercredi 20 juin 2012, à Paris, au Musée du Louvre et, d’autre part, les «  Rencontres autour de la sculpture romaine conservée en France  » qui ont eu lieu du 18 au 20 octobre 2012 au Musée départemental Arles antique. La richesse des interventions lors de ces deux manifestations permet de restituer un ouvrage composé de trente-huit articles, répartis en trois parties et une conclusion. La première partie, en écho et en développement de la table ronde du Louvre, porte sur le portrait du «  César du Rhône  », aussi bien que sur «  Le portrait romain en Gaule  ». La deuxième partie publie cinq études autour des «  nouvelles techniques d’investigations scientifiques  » et présente l’analyse des matériaux des sculptures en pierre et en bronze, découvertes dans le Rhône à Arles, ainsi qu’une étude ethnoarchéologique sur les techniques de production du portrait. Enfin une troisième partie présente les «  découvertes récentes et les nouvelles recherches  », déclinées en seize études qui sont consacrées à des études de cas (Autun, Vaison-la-Romaine, Nîmes, Metz-Divodurum, Apt), ainsi qu’à des relectures novatrices de sculptures méconnues (Plouarzel, Langres, Avignonet-Lauragais, Vernègues, vallée de l’Ubaye, Besançon, Lyon). Robert Turcan signe la conclusion. Ainsi, «  La sculpture romaine en Occident. Nouveaux regards   » reflète la variété et l’intérêt des questionnements actuels dans ce domaine

Standards for plant synthetic biology: a common syntax for exchange of DNA parts.

Inventors in the field of mechanical and electronic engineering can access multitudes of components and, thanks to standardization, parts from different manufacturers can be used in combination with each other. The introduction of BioBrick standards for the assembly of characterized DNA sequences was a landmark in microbial engineering, shaping the field of synthetic biology. Here, we describe a standard for Type IIS restriction endonuclease-mediated assembly, defining a common syntax of 12 fusion sites to enable the facile assembly of eukaryotic transcriptional units. This standard has been developed and agreed by representatives and leaders of the international plant science and synthetic biology communities, including inventors, developers and adopters of Type IIS cloning methods. Our vision is of an extensive catalogue of standardized, characterized DNA parts that will accelerate plant bioengineering.Biotechnological and Biological Sciences Research Council (BBSRC). Grant Numbers: BB/K005952/1, BB/L02182X/1 Synthetic Biology Research Centre ‘OpenPlant’ award. Grant Number: BB/L014130/1 Spanish MINECO. Grant Number: BIO2013‐42193‐R Engineering Nitrogen Symbiosis for Africa (ENSA) The Bill & Melinda Gates Foundation US Department of Energy, Office of Biological and Environmental. Grant Number: DE‐AC02‐05CH1123 COST Action. Grant Number: FA100

Les Caractères de La Bruyère entre poétique de la morale et immoralité de la poétique

PARIS4-BU Serpente (751052129) / SudocST QUENTIN EN YVELINES-BU (782972101) / SudocSudocFranceF

Andrea Giardina (dir.), Società romana e impero tardoantico, t. 1: Istituzioni, ceti, economia ; t. 2: Roma : politica, economia, paesaggio urbano ; t. 3: Le merci, gli insediamenti ; Tradizione dei classici, trasformazioni della cultura

Andreau Jean, Leveau Philippe. Andrea Giardina (dir.), Società romana e impero tardoantico, t. 1: Istituzioni, ceti, economia ; t. 2: Roma : politica, economia, paesaggio urbano ; t. 3: Le merci, gli insediamenti ; Tradizione dei classici, trasformazioni della cultura. In: Annales. Économies, Sociétés, Civilisations. 47ᵉ année, N. 2, 1992. pp. 402-408