1,113 research outputs found
L2: EFFECTIVENESS OF ORAL CIPROFLOXACIN IN THE TREATMENT OF EXACERBATIONS OF CHRONIC AIRWAY DISEASES
Equilibrium bitcoin pricing
We offer an overlapping generations equilibrium model of cryptocurrency pricing and confront it to new data on bitcoin transactional benefits and costs. The model emphasizes that the fundamental value of the cryptocurrency is the stream of net transactional benefits it will provide, which depend on its future prices. The link between future and present prices implies that returns can exhibit large volatility unrelated to fundamentals. We construct an index measuring the ease with which bitcoins can be used to purchase goods and services, and we also measure costs incurred by bitcoin owners. Consistent with the model, estimated transactional net benefits explain a statistically significant fraction of bitcoin returns
Equilibrium bitcoin pricing
We offer an overlapping generations equilibrium model of cryptocurrency pricing and confront it to new data on bitcoin transactional benefits and costs. The model emphasizes that the fundamental value of the cryptocurrency is the stream of net transactional benefits it will provide, which depend on its future prices. The link between future and present prices implies that returns can exhibit large volatility unrelated to fundamentals. We construct an index measuring the ease with which bitcoins can be used to purchase goods and services, and we also measure costs incurred by bitcoin owners. Consistent with the model, estimated transactional net benefits explain a statistically significant fraction of bitcoin returns
Scientific, Technical and Economic Committee for Fisheries (STECF) - Report of the STECF Study Group on the Evaluation of Fishery Multi-annual Plans (SGMOS 09-02)
SG-MOS 09-02 was held in IPIMAR, Lisbon, (Portugal), on 23-27 November 2009. The aim of the
workshop was to provide Evaluations of three multiannual fisheries management plans:- R(EC) No
388/2006 ¿ multi-annual plan for sole in the Bay of Biscay; R(EC) No 209/2007 ¿ multi-annual plan for sole
in the Western Channel R(EC) No676/2007 ¿ multi-annual plan for sole and plaice in the North Sea.
STECF reviewed the report during its Plenary meeting on 26-30 April 2010.JRC.DG.G.4-Maritime affair
c-di-GMP modulates type IV MSHA pilus retraction and surface attachment in Vibrio cholerae.
Biofilm formation by Vibrio cholerae facilitates environmental persistence, and hyperinfectivity within the host. Biofilm formation is regulated by 3',5'-cyclic diguanylate (c-di-GMP) and requires production of the type IV mannose-sensitive hemagglutinin (MSHA) pilus. Here, we show that the MSHA pilus is a dynamic extendable and retractable system, and its activity is directly controlled by c-di-GMP. The interaction between c-di-GMP and the ATPase MshE promotes pilus extension, whereas low levels of c-di-GMP correlate with enhanced retraction. Loss of retraction facilitated by the ATPase PilT increases near-surface roaming motility, and impairs initial surface attachment. However, prolonged retraction upon surface attachment results in reduced MSHA-mediated surface anchoring and increased levels of detachment. Our results indicate that c-di-GMP directly controls MshE activity, thus regulating MSHA pilus extension and retraction dynamics, and modulating V. cholerae surface attachment and colonization
Why is order flow so persistent?
Order flow in equity markets is remarkably persistent in the sense that order
signs (to buy or sell) are positively autocorrelated out to time lags of tens
of thousands of orders, corresponding to many days. Two possible explanations
are herding, corresponding to positive correlation in the behavior of different
investors, or order splitting, corresponding to positive autocorrelation in the
behavior of single investors. We investigate this using order flow data from
the London Stock Exchange for which we have membership identifiers. By
formulating models for herding and order splitting, as well as models for
brokerage choice, we are able to overcome the distortion introduced by
brokerage. On timescales of less than a few hours the persistence of order flow
is overwhelmingly due to splitting rather than herding. We also study the
properties of brokerage order flow and show that it is remarkably consistent
both cross-sectionally and longitudinally.Comment: 42 pages, 15 figure
Equilibrium Bitcoin Pricing
We offer an overlapping generations equilibrium model of cryptocurrency pricing and confront it to new data on bitcoin transactional benefits and costs. The model emphasizes that the fundamental value of the cryptocurrency is the stream of net transactional benefits it will provide, which depend on its future prices. The link between future and present prices implies that returns can exhibit large volatility unrelated to fundamentals. We construct an index measuring the ease with which bitcoins can be used to purchase goods and services, and we also measure costs incurred by bitcoin owners. Consistent with the model, estimated transactional net benefits explain a statistically significant fraction of bitcoin returns
Speed, Algorithmic Trading, and Market Quality Around Macroeconomic News Announcements
Direct Mechanisms, Menus and Latent Contracts
In common agency games, one cannot characterize all equilibria by considering only direct mechanisms. In an attempt to overcome this difficulty, Peters [Econometrica, 2001]and Martimort and Stole [Econometrica, 2002] identified a class of indirect mechanisms (namely, menus) which are able to characterize every equilibrium. Unfortunately, menus are difficult to handle, and several methodologies have been proposed in the literature. Here, it is shown that, even if authors consider menus rather than simpler mechanisms, many equilibria described in the literature could have been characterized by direct incentive compatible mechanisms. Use of more sophisticated mechanisms was not necessary in these cases
A model for a large investor trading at market indifference prices. I: single-period case
We develop a single-period model for a large economic agent who trades with
market makers at their utility indifference prices. A key role is played by a
pair of conjugate saddle functions associated with the description of Pareto
optimal allocations in terms of the utility function of a representative market
maker.Comment: Shorten from 69 to 30 pages due to referees' requests; a part of the
previous version has been moved to "The stochastic field of aggregate
utilities and its saddle conjugate", arXiv:1310.728
- …