512 research outputs found
Coherently manipulating flying qubits in a quantum wire with a magnetic impurity
e study the effect of a magnetic impurity with spin-half on a single
propagating electron in a one-dimensional model system via the tight-binding
approach. Due to the spin-dependent interaction, the scattering channel for the
flying qubit is split, and its transmission spectrum is obtained. It is found
that, the spin orientation of the impurity plays the role as a spin state
filter for a flying qubit.Comment: 6 pages, 5 figure
Atrapamiento alveolar y diseminación interalveolar en carcinoma pulmonar no microcítico : correlación con la expresión de antígeno de grupo A, proteínas de choque térmico, estadificación y supervivencia
[ABSTRACT] Lung carcinoma is the second most common cancer worldwide, following prostatic carcinoma in incidence but it remains the highest in mortality. The five year survival varies depending on the geographical areas but it ranges between 6 and 14% for males and between 7 and 18% for females, in such way that the total deaths due to pulmonary carcinoma are higher than those caused by colonic, mammary and prostatic carcinomas together, in spite of the advances in diagnosis and therapeutics. Even among patients with localized disease who are treated with surgical resection, 73% and 58% of them, respectively in stage IA and IB, live longer than 5 years. Further studies in order to discriminate which cases purported either a favorable or dismal clinical course are pivotal to know the patients who will need additional treatment and to look for new and more specific therapies. Nowadays, in the molecular age, a so classic and conventional procedure as staging constitutes the most important isolated factor to determine the survival, predict the prognosis, select the therapies and stratify the patients. Histological features of the nonsmall cell lung carcinoma (NSCLC) as prognostic factors have been variously studied with diverse and not uniform results. So the histologic type of the tumor, grade of differentiation, growth pattern at the periphery of the tumor, necrosis, presence of scar and desmoplasia inside the neoplasm, vascular invasion either lymphatic, venous or even arterial; mitotic count have been studied with diverse and sometimes contradictory results depending on the different series. Among the most constant microscopic features with prognostic implications are: vascular invasion, desmoplasia and some histologic patterns or variations as micropapillar areas in adenocarcinoma (AC), carcinomas with rhabdoid differentiation as unfavorable factors or bronchioloalveolar carcinoma (BC) or extensive areas with this bronchioloalveolar pattern as favorable ones..
Bioaccessibility of metals and human health risk assessment in community urban gardens
Pseudo-total (i.e. aqua regia extractable) and gastric-bioaccessible (i.e. glycine + HCl extractable) concentrations of Ca, Co, Cr, Cu, Fe, Mn, Ni, Pb and Zn were determined in a total of 48 samples collected from six community urban gardens of different characteristics in the city of Madrid (Spain). Calcium carbonate appears to be the soil property that determines the bioaccessibility of a majority of those elements, and the lack of influence of organic matter, pH and texture can be explained by their low levels in the samples (organic matter) or their narrow range of variation (pH and texture). A conservative risk assessment with bioaccessible concentrations in two scenarios, i.e. adult urban farmers and children playing in urban gardens, revealed acceptable levels of risk, but with large differences between urban gardens depending on their history of land use and their proximity to busy areas in the city center. Only in a worst-case scenario in which children who use urban gardens as recreational areas also eat the produce grown in them would the risk exceed the limits of acceptabilit
Arsenic, antimony and selenium in urban soils: potential risks for human health in urban gardening
The benefits of urban agriculture are many and well documented, ranging from health improvement to community betterment, more sustainable urban development and environment protection. On the negative side, urban soils are commonly enriched in toxic trace elements that have accumulated over time through the deposition of atmospheric particles (generated by automotive traffic, heating systems, historical industrial activities and resuspended street dust), and the uncontrolled disposal of domestic, commercial and industrial wastes. This in turn has given rise to concerns about the level of exposure of urban farmers to these elements and the potential health hazards associated with this exposure. Research efforts in this field have started relatively recently and have almost systematically omitted the influence of Sb and Se, and to a lesser extent of As, although all three have proven toxic effects
Preparing for generation Z:how can technology enhanced learning be firmly embedded in our students' learning experience? A case study from Abertay University
Abertay is a relatively small, modern university (undergraduate population of around 4000) with a wide portfolio and a diverse student population. Around 35% of our students are direct entry from local partner colleges to years 2 and 3 of our programmes and a significant number are first generation higher education within their families. As such, partnership working with colleges and support to aid student transitions are key aspects of Abertay’s provision. Since 2013/14, the university has developed and implemented a new Teaching and Learning Enhancement strategy that has catalysed wholescale transformation across the institution. This paper provides an overview of technology enhanced learning at the university with the drivers for change being to the quality of our students' learning experience, improve student retention and progression and enhance learners’ engagement
Dual VET in the EU policy: the internationalization of the german model?
Some European countries, including Spain, encouraged by the European Union, have undertaken the reform of their Vocational Training systems so as to promote dual apprenticeship. This research analyses EU documentation, consisting of documents related to the Copenhagen process and VET reform, such as communications, recommendations, and declarations from different European bodies. This analysis will focus on EU proposals and recommendations on two areas of VET: the governance system and the training model which are the main characteristics of the German model of VET. The methodology consists of reflective thematic analysis, using NVIVO's qualitative data analysis computer software. This will advance the understanding of the process of internationalisation and attraction of the German dual VET model within the EU as a model of good practice.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech
Mesoporous Silica Nanoparticles for Drug Delivery: Current Insights
This manuscript reviews the recent progress on mesoporous silica nanoparticles as drug delivery systems. Their intrinsic structural, textural and chemical features permit to design versatile multifunctional nanosystems with the capability to target the diseased tissue and release the cargo on demand upon exposition to internal or external stimuli. The degradation rate of these nanocarriers in diverse physiological fluids is overviewed obeying their significance for their potential translation towards clinical applications. To conclude, the balance between the benefits and downsides of this revolutionary nanotechnological tool is also discussed
Bioaccessibility of heavy metals and risk assessment in urban gardens of Madrid
Human health problems and solutions. Urban gardening has spread worldwide in recent years as it enhances food security and selfsupply and promotes community integration. However urban soils are significantly enriched in trace elements relative to background levels. Exposure to the soil in urban gardens may therefore result in adverse health effects depending on the degree of contact during gardening, infant recreational activities and ingestion of vegetables grown in them. In order to evaluate this potential risk, 36 composite samples were collected from the top 20 cm of the soil of 6 urban gardens in Madrid. The aqua regia (pseudototal) and glycine-extractable (bioaccessible) concentrations of Co, Cr, Cu, Ni, Pb and Zn were determined by atomic absorption spectrophotometry. Additionally, pH, texture, Fe, Ca, and Mn concentrations, and organic matter and calcium carbonate contents were determined in all urban gardens and their influence on trace element bioaccessibility was analyzed
Co-Existence of Inoculated Yeast and Lactic Acid Bacteria and Their Impact on the Aroma Profile and Sensory Traits of Tempranillo Red Wine
This study investigates the effects of simultaneous inoculation of a selected Saccharomyces cerevisiae yeast strain with two different commercial strains of wine bacteria Oenococcus oeni at the beginning of the alcoholic fermentation on the kinetics of malolactic fermentation (MLF), wine chemical composition, and organoleptic characteristics in comparison with spontaneous MLF in Tempranillo grape must from Castilla-La Mancha (Spain). Evolution of MLF was assessed by the periodic analysis of L-malic acid through the enzymatic method, and most common physiochemical parameters and sensory traits were evaluated using a standardized sensory analysis. The samples were analyzed by GC/MS in SCAN mode using a Trace GC gas chromatograph and a DSQII quadrupole mass analyzer. Co-inoculation reduced the overall fermentation time by up to 2 weeks leading to a lower increase in volatile acidity. The fermentation-derived wine volatiles profile was distinct between the co-inoculated wines and spontaneous MLF and was influenced by the selected wine bacteria used in co-inoculation. Co-inoculation allows MLF to develop under reductive conditions and results in wines with very few lactic and buttery flavors, which is related to the impact of specific compounds like 2,3-butanedione. This compound has been also confirmed as being dependent on the wine bacteria use
Planar ESPAR Array Design with Nonsymmetrical Pattern by Means of Finite-Element Method, Domain Decomposition, and Spherical Wave Expansion
The application of a 3D domain decomposition finite-element and spherical mode expansion for the design of planar ESPAR (electronically steerable passive array radiator) made with probe-fed circular microstrip patches is presented in this work. A global generalized scattering matrix (GSM) in terms of spherical modes is obtained analytically from the GSM of the isolated patches by using rotation and translation properties of spherical waves. The whole behaviour of the array is characterized including all the mutual coupling effects between its elements. This procedure has been firstly validated by analyzing an array of monopoles on a ground plane, and then it has been applied to synthesize a prescribed radiation pattern optimizing the reactive loads connected to the feeding ports of the array of circular patches by means of a genetic algorithm
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