Diagnóstico de la EPOC

La presencia de síntomas puede ser extremadamente variable en los pacientes con EPOC, y un diagnóstico firme sólo puede ser confirmado objetivando una limitación al flujo aéreo mediante la realización de una espirometría

Diagnóstico de la EPOC

La presencia de síntomas puede ser extremadamente variable en los pacientes con EPOC, y un diagnóstico firme sólo puede ser confirmado objetivando una limitación al flujo aéreo mediante la realización de una espirometría

Sistema portátil para determinar compuestos orgánicos volátiles en suelos

Referencia OEPM: P9602622.-- Fecha de solicitud: 10/12/1996.-- Titular: Consejo Superior de Investigaciones Científicas (CSIC).Sistema portátil para determinar compuestos orgánicos volátiles en suelos. Sistema compuesto de: 1) multisonda, constituida por 16 elementos sensores resistivos preparados mediante la tecnología de película delgada: sputtering; 2) sistema de calefacción controlado e incorporado en la cabeza multisensora; 3) software y equipo informático para la adquisición, tratamiento y análisis de datos. Con este equipo de medida se pueden medir in situ y en continuo y por lo tanto resuelve el problema actual de medición.Peer reviewe

Electrical characterization of a thin film tin oxide sensor array for VOCs detection

A tin oxide sensor array has been fabricated using the r.f. reactive sputtering technique. Some elements of the array have been doped with Pt, Pd and Al by sputtering. Sensors have been characterized by DC electrical measurements for different volatile organic compounds (VOCs) such as benzene, toluene, chloroform, propanal, methyl-ethyl-ketone (MEK) and octane, in a concentration range from 50 to 500 ppm in dry air at 300°C. The best response has been obtained by Pt and Pd doped sensors for the oxygenated compounds, but for all gases good sensitivities are shown. The impedance spectra were obtained by AC variable-frequency measurements for all the sensors in air, in benzene and in propanal atmospheres at 300°C. The VOCs peak frequencies changed with regard to air peak frequencies for all the sensors. The roles of dopants and doping level are discussed. © 1998 Elsevier Science S.A.Peer Reviewe

Onset of Nut Allergy in a Pediatric Cohort: Clinical and Molecular Patterns in the AFRUSEN Study.

Nut allergy is a growing problem, yet little is known about its onset in children. Objective: To characterize the onset of nut allergy in children in southern Europe. The study population comprised consecutive patients up to 14 years of age who visited allergy departments with an initial allergic reaction to peanut, tree nut, or seed. The allergy work-up included a clinical history, food challenge, skin prick testing, determination of whole-extract sIgE, and ImmunoCAP ISAC-112 assay. Of the 271 children included, 260 were first diagnosed with nut allergy at a mean age of 6.5 years and at a mean (SD) of 11.8 (21.2) months after the index reaction. The most common culprit nuts at onset were walnut (36.5%), peanut (28.5%), cashew (10.4%), hazelnut (8.5%), pistachio (5.4%), and almond (5%). Onset of peanut allergy was more frequent in children ≤6 years and walnut in those aged >6 years (P=.032). In 65% of cases, the allergic reaction occurred the first time the patient consumed the nut, and 35% of reactions were anaphylactic. Overall, polysensitization to nuts was detected by skin prick testing in 64.9% of patients, although this rate was lower among walnut-allergic children (54.7%) and peanut-allergic children (54.1%) (P6 years (P=.032). In 65% of cases, the allergic reaction occurred the first time the patient consumed the nut, and 35% of reactions were anaphylactic. Overall, polysensitization to nuts was detected by skin prick testing in 64.9% of patients, although this rate was lower among walnut-allergic children (54.7%) and peanut-allergic children (54.1%) (P In the population we assessed, the onset of nut allergy occurred around 6 years of age, slightly later than that reported in English-speaking countries. Walnut was the main trigger, followed by peanut. 2S albumin storage proteins, especially Jug r 1, were the most relevant allergens. This study will help guide management and may contribute to preventive strategies in pediatric nut allergy