Statistical Measures for Usage‐Based Linguistics

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/111781/1/lang12119.pd

When workplace unionism in global value chains does not function well : exploring the impediments

Improving working conditions at the bottom of global value chains has become a central issue in our global economy. In this battle, trade unionism has been presented as a way for workers to make their voices heard. Therefore, it is strongly promoted by most social standards. However, establishing a well-functioning trade union is not as obvious as it may seem. Using a comparative case study approach, we examine impediments to farm-level unionism in the cut flower industry in Ethiopia. For this purpose, we propose an integrated framework combining two lenses, namely a vertical one (governance and structure of global value chains) and a horizontal one (socio-economic context). We identify 10 impediments that point to three major dimensions contributing to unionisation. These three dimensions include awareness of and interest from workers, legitimacy of trade unions, and capacity of trade unions to act. Furthermore, our results suggest that private social standards may, in certain cases, be counterproductive for the efficient functioning of trade unions. Although we argue that there is no ‘quick fix’ solution to weak workplace unionism at the bottom of global value chains, we stress the importance of considering the dynamics of, and interactions between, the impediments when designing potential support measures that mitigate negative impacts

Assessing and facilitating warehouse safety

Purpose – The purpose of this paper is to investigate how warehouse safety can be assessed and facilitated. Methodology – Through a literature study, we build a theoretical framework to provide insights in how safety in Logistics Service Providers (LSPs) can be assessed and facilitated. We perform a case study at a large Dutch LSP using interviews and questionnaires to determine the relevance of the sub-dimensions to assess warehouse safety. Findings – Using literature, we identify people, procedures and technology related sub-dimensions of safety culture and safety behavior and factors that may affect how safety culture translates to safety behavior. Using a case study our findings indicate which sub-dimensions and influencing factors LSP employees find important and why. We found differences in the importance assigned to safety, which may point to the existence of sub-cultures across warehouses. Research limitations/implications – This paper contributes to the limited existing warehouse safety literature in which the factors that influence safety are not well explored. Although the case study investigates one LSP and as such does not generalize across LSPs, it provides valuable insights in important aspects of safety and how they can be influenced. Practical implications – This paper offers safety managers insights in how to assess and facilitate safety within their warehouses. Originality – Although warehouse safety is important, there is scarce academic research that explores this issue

Ten-year mortality, disease progression, and treatment-related side effects in men with localised prostate cancer from the ProtecT randomised controlled trial according to treatment received

Background The ProtecT trial reported intention-to-treat analysis of men with localised prostate cancer randomly allocated to active monitoring (AM), radical prostatectomy, and external beam radiotherapy. Objective To report outcomes according to treatment received in men in randomised and treatment choice cohorts. Design, setting, and participants This study focuses on secondary care. Men with clinically localised prostate cancer at one of nine UK centres were invited to participate in the treatment trial comparing AM, radical prostatectomy, and radiotherapy. Intervention Two cohorts included 1643 men who agreed to be randomised and 997 who declined randomisation and chose treatment. Outcome measurements and statistical analysis Analysis was carried out to assess mortality, metastasis and progression and health-related quality of life impacts on urinary, bowel, and sexual function using patient-reported outcome measures. Analysis was based on comparisons between groups defined by treatment received for both randomised and treatment choice cohorts in turn, with pooled estimates of intervention effect obtained using meta-analysis. Differences were estimated with adjustment for known prognostic factors using propensity scores. Results and limitations According to treatment received, more men receiving AM died of PCa (AM 1.85%, surgery 0.67%, radiotherapy 0.73%), whilst this difference remained consistent with chance in the randomised cohort (p = 0.08); stronger evidence was found in the exploratory analyses (randomised plus choice cohort) when AM was compared with the combined radical treatment group (p = 0.003). There was also strong evidence that metastasis (AM 5.6%, surgery 2.4%, radiotherapy 2.7%) and disease progression (AM 20.35%, surgery 5.87%, radiotherapy 6.62%) were more common in the AM group. Compared with AM, there were higher risks of sexual dysfunction (95% at 6 mo) and urinary incontinence (55% at 6 mo) after surgery, and of sexual dysfunction (88% at 6 mo) and bowel dysfunction (5% at 6 mo) after radiotherapy. The key limitations are the potential for bias when comparing groups defined by treatment received and changes in the protocol for AM during the lengthy follow-up required in trials of screen-detected PCa. Conclusions Analyses according to treatment received showed increased rates of disease-related events and lower rates of patient-reported harms in men managed by AM compared with men managed by radical treatment, and stronger evidence of greater PCa mortality in the AM group. Patient summary More than 95 out of every 100 men with low or intermediate risk localised prostate cancer do not die of prostate cancer within 10 yr, irrespective of whether treatment is by means of monitoring, surgery, or radiotherapy. Side effects on sexual and bladder function are better after active monitoring, but the risks of spreading of prostate cancer are more common

Functional and quality of life outcomes of localised prostate cancer treatments (prostate testing for cancer and treatment [ProtecT] study)

Objective To investigate the functional and quality of life (QoL) outcomes of treatments for localised prostate cancer and inform treatment decision-making. Patients and Methods Men aged 50–69 years diagnosed with localised prostate cancer by prostate-specific antigen testing and biopsies at nine UK centres in the Prostate Testing for Cancer and Treatment (ProtecT) trial were randomised to, or chose one of, three treatments. Of 2565 participants, 1135 men received active monitoring (AM), 750 a radical prostatectomy (RP), 603 external-beam radiotherapy (EBRT) with concurrent androgen-deprivation therapy (ADT) and 77 low-dose-rate brachytherapy (BT, not a randomised treatment). Patient-reported outcome measures (PROMs) completed annually for 6 years were analysed by initial treatment and censored for subsequent treatments. Mixed effects models were adjusted for baseline characteristics using propensity scores. Results Treatment-received analyses revealed different impacts of treatments over 6 years. Men remaining on AM experienced gradual declines in sexual and urinary function with age (e.g., increases in erectile dysfunction from 35% of men at baseline to 53% at 6 years and nocturia similarly from 20% to 38%). Radical treatment impacts were immediate and continued over 6 years. After RP, 95% of men reported erectile dysfunction persisting for 85% at 6 years, and after EBRT this was reported by 69% and 74%, respectively (P < 0.001 compared with AM). After RP, 36% of men reported urinary leakage requiring at least 1 pad/day, persisting for 20% at 6 years, compared with no change in men receiving EBRT or AM (P < 0.001). Worse bowel function and bother (e.g., bloody stools 6% at 6 years and faecal incontinence 10%) was experienced by men after EBRT than after RP or AM (P < 0.001) with lesser effects after BT. No treatment affected mental or physical QoL. Conclusion Treatment decision-making for localised prostate cancer can be informed by these 6-year functional and QoL outcomes

Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission

AbstractUnderstanding SARS-CoV-2 transmission in higher education settings is important to limit spread between students, and into at-risk populations. In this study, we sequenced 482 SARS-CoV-2 isolates from the University of Cambridge from 5 October to 6 December 2020. We perform a detailed phylogenetic comparison with 972 isolates from the surrounding community, complemented with epidemiological and contact tracing data, to determine transmission dynamics. We observe limited viral introductions into the university; the majority of student cases were linked to a single genetic cluster, likely following social gatherings at a venue outside the university. We identify considerable onward transmission associated with student accommodation and courses; this was effectively contained using local infection control measures and following a national lockdown. Transmission clusters were largely segregated within the university or the community. Our study highlights key determinants of SARS-CoV-2 transmission and effective interventions in a higher education setting that will inform public health policy during pandemics.</jats:p

0406 Daytime Sleepiness in The Community: Implications for Sleep, Circadian, and Physical Health

Abstract Introduction Daytime sleepiness impacts performance and well-being. The present study used validated measures to explore associations of community-level daytime sleepiness with sleep health, preferred sleep phase, physical inactivity, and overall health. Methods Data were from the Sleep and Healthy Activity, Diet, Environment, and Socialization (SHADES) study of N=1007 adults age 22-60 from the community. Daytime sleepiness was assessed with the Epworth Sleepiness Scale (ESS). Outcomes of interest included the Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), endorsement of a preference for an advanced or delayed sleep phase on the Sleep Disorders Symptom Check List (SDSCL), STOP-BANG sleep apnea questionnaire score, sedentary time assessed with the International Physical Activity Questionnaire (IPAQ), and the global health item on the SF-12, operationalized as excellent/good or fair/poor health. Through regression analyses, we assessed whether daytime sleepiness was independently associated with several sleep, circadian and physical health outcomes, adjusting for habitual sleep duration and sociodemographic factors like age, sex, education, and race/ethnicity. Results Our adjusted models indicate that daytime sleepiness was associated with insomnia (B=0.57; 95%CI: 0.50, 0.65; p<0.0001), sleep quality (B=0.34; 95%CI: 0.29, 0.39; p<0.0001), advanced sleep phase (OR=1.06; 95%CI: 1.03, 1.09; p<0.0001), delayed sleep phase (OR=1.05; 95%CI: 1.02, 1.07; p=0.0003), STOP-BANG score (B=0.08; 95%CI: 0.07, 0.10; p<0.0001), sedentary minutes (B=6.12; 95%CI: 2.77, 9.47; p=0.0004), and overall poor health (OR=1.10; 95%CI: 1.07, 1.13; p<0.0001). After additional adjustment for habitual sleep duration, all relationships were maintained. Conclusion Daytime sleepiness is associated with more severe insomnia, preference for advanced or delayed sleep timing, worse sleep quality, and greater risk of sleep apnea. Moreover, daytime sleepiness was associated with greater sedentary time and worse overall health. Since these relationships are independent of sleep duration, they likely do not reflect an effect of sleep deprivation. Support This work was supported by a grant from Jazz Pharmaceuticals. The SHADES study was funded by R21ES022931. Dr. Grandner is supported by R01MD011600

Prospects for Labour in Global Value Chains: Labour Standards in the Cut Flower and Banana Industries

Global value chain (GVC) governance is central to analyses of labour's strategic options. It frames the terrain on which labour campaigns and institutions — such as private social standards and international framework agreements — contribute to the social regulation of value chains. GVC concepts help to emphasize how power in the employment relationship transcends organizational boundaries, as well as how industrial power is shifting from the sphere of production to that of consumption. Based on extensive case studies of the banana and cut flower value chains, we explore the implications of GVC restructuring for the scope and form of labour rights strategies.