226 research outputs found

    Chronicles of Oklahoma

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    Article discusses a program led by Dartmouth College to provide education to youths from Indian Territory, and discusses some of the Cherokee and Choctaw alumni that attended the liberal arts institution. Kathleen Garrett also provides historical background to the establishment of the school

    Chronicles of Oklahoma

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    Article discusses the music curriculum at the Cherokee National Female Seminary and the drive made by the music teacher to teach the daughters of the Edmondson family, the focus of the article. Kathleen Garrett explores the growth of music in Indian Territory

    Nesting Ecology of the White-Faced Ibis (Plegadis Chihi) in Southwestern Louisiana.

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    I studied the nesting ecology of the White-faced Ibis (Plegadis chihi) during the summers of 1994 and 1995 in three colonies in Lacassine National Wildlife Refuge, southwestern Louisiana. Data were collected on colony-site characteristics, chronology (with abundance) of colony formation, reproductive success, and growth and development of ibis nestlings. Small colonies nested in dense buttonbush (Cephalanthus occidentalis) and water willow (Decodon verticillatus) islands. The largest colony nested in black willows (Salix nigra) (3.2 ha)--a habitat unique to ibis populations in Louisiana--with nests heights up to 7.5 m. Cattle egrets (Bubulcus ibis) (62%) and ibises (36%) were the most abundant species. Ibis nesting began on 23 May; hatching occurred between 19 June and 16 July. I assessed reproductive success of 292 nests with 262 chicks. In 1994 and 1995, clutches averaged 2.8 and 2.6 eggs; hatching rates (fertility) were 90% and 93%; hatching success was 41% in 1994 and 1% (in 64% of the colony) and 74% (elsewhere) in 1995; 14-day fledgling success was 33% and 37%. Survival was highly correlative with hatching order: first hatched were most likely to survive. Estimated colony success was 491 fledglings from 1,292 nests (0.38) in 1994 and 149 from 622 nests (0.24) in 1995. Major environmental differences between years were higher water, more alligators (Alligator mississippiensis), and fewer mammalian predators in 1994. Extensive predation by raccoons (Procyon lotor), mustelids, avian predators, alligators, and snakes caused most nest failures (67% and 96% each year). Minor causes included infertile eggs and collapsed and abandoned nests. Nests were more successful when substrate was black willow (vs. other tree species), over water (vs. land), in upper or lower tree heights (vs. middle), and on the edge of the colony. Nearest-neighbor species did not affect success, but nearest-neighbor distance had some effect. Measurements of the culmen, forearm, tarsus, and mass were taken of 92 chicks, the oldest was 20 days old. A chick\u27s growth was not affected by brood size or if it survived to fledge, but was slightly affected by year and hatching order. Nestlings\u27 regurgitated pellets contained water bugs, beetles, and horsefly and dragonfly larvae

    Nebraska Child Care Market Rate Survey Report 2019

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    The Child Care and Development Block Grant (CCDBG) Act of 2014 was reauthorized with renewed emphasis placed on the Child Care and Development Fund (CCDF) program, which seeks to provide equal access to quality child care for families. The CCDF program is necessary to ensure children from low-income families have the opportunity to experience stable, high-quality early experiences while their parents experience a pathway to economic stability. A primary goal of the CCDF program is to ensure that low-income families receive CCDF funds to help them access quality child care in the same manner as families that pay the full rate for child care services (Davis et al., 2017). The CCDBG Act requires Lead Agencies to engage in a number of activities designed to inform families receiving CCDF assistance, the general public, and child care providers of various aspects of the new law. This includes a requirement for Lead Agencies to conduct a market rate survey or alternative methodology to establish provider payment rates. Various factors should be considered when provider payment rates are established to ensure children from low-income families have equal access to highquality child care. Federal regulations indicate that the 75th percentile payment rate is a benchmark for gauging equal access for families receiving subsidy. However, States/ Territories are given the freedom to determine their own rates and eligibility requirements for families and programs. The Nebraska Department of Health and Human Services (NDHHS) is the CCDF Lead Agency in Nebraska. While the reauthorized CCDBG allows states to conduct a market rate survey every three years, state legislation requires that NDHHS adjust the reimbursement rate for child care every odd numbered year. For 2019, NDHHS contracted with the Buffett Early Childhood Institute (referred to as Institute throughout the remainder of this manuscript) at the University of Nebraska to conduct a market rate survey (MRS) for child care in the state of Nebraska. The 2019 MRS was designed to meet the following federal benchmarks: (a) includes the priced child care market; (b) provides complete and current data; (c) represents geographic variations; (d) uses rigorous data collection procedures; and (e) analyzes data in a manner that captures market differences as a function of age group, provider type, and geographic location (45 CFR § 98.4)

    Integrating Indigenous Knowledge and Western Science into Forestry, Natural Resources, and Environmental Programs

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    A new minor titled “Indigenous Studies in Natural Resources and the Environment” (INRE) became available to students at California Polytechnic State University in San Luis Obispo, California, in the fall of 2013. This minor aims to bring together the principles of both Indigenous ecological knowledge and western science. Instruction in these two approaches provides students with practical knowledge, research, and critical thinking skills to address complex environmental issues and natural resources management problems facing both Indigenous and non-Indigenous communities around the world today. The INRE minor seeks to prepare students by providing a balanced education in the arts, sciences, and technology, while encouraging interdisciplinary and co-curricular activities. This article reports on the need for the INRE minor, learning outcomes, curriculum, approval process, student interest surveys, and enrolled INRE students\u27 focus group comments. This program may serve as a model for other academic institutions to bridge the gap between western and Indigenous science regarding the environment. Management and Policy Implications: Society of American Foresters members are called to abide by a Code of Ethics10 whose first Principle and Pledge states: “Foresters have a responsibility to manage land for current and future generations. We pledge to practice and advocate management that will maintain the long-term capacity of the land to provide the variety of materials, uses, and values desired by landowners and society.” How can foresters and land managers achieve this pledge? Integration of Indigenous and western science into university curricula and professional disciplines could lead to enhanced collaboration and stewardship of public and tribal lands. Cal Poly\u27s new Indigenous Studies in Natural Resources and the Environment (INRE) minor works to foster communication and collaboration across academic disciplines and programs by helping people better understand and respect the land, natural resources, and ecosystems. By presenting the INRE minor design and its learn-by-doing approach to resolving land, forest, and natural resource conflicts, we hope other academic institutions will use this program as a model to bridge the gap between western science and Indigenous knowledge of the environment, as well as to instill in the next generations of foresters a broader resource and land ethic

    Chronologic distribution of stroke after minimally invasive versus conventional coronary artery bypass

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    AbstractObjectivesWe sought to investigate whether the chronologic distribution of the onset of stroke occurring after coronary artery bypass graft surgery (CABG) without cardiopulmonary bypass (off-pump CABG) is different from the conventional on-pump approach (CABG with cardiopulmonary bypass).BackgroundOff-pump CABG has been associated with a lower stroke rate, compared with conventional on-pump CABG. However, it is unknown whether the chronologic distribution of the onset of stroke is different between the two approaches.MethodsWe evaluated the chronologic distribution of postoperative stroke in patients undergoing CABG from June 1996 to August 2001 (n = 10,573). Preoperative risk factors for stroke were identified using the Northern New England preoperative estimate of stroke risk. Multivariate logistic regression analysis was used to determine the independent predictors of early stroke and to delineate the association between the surgical approach and the chronologic distribution of the onset of stroke.ResultsStroke occurred in 217 patients (2%, n = 10,573). A total of 44 (20%) and 173 (80%) of these patients had stroke after off-pump CABG and on-pump CABG, respectively. The median time for the onset of stroke was two days (range 0 to 11 days) after on-pump CABG versus four days (range 0 to 14 days) after off-pump CABG (p < 0.01). On-pump CABG was associated with a higher risk of early stroke (odds ratio 5.3, 95% confidence interval 2.6 to 10.9; p < 0.01) compared with off-pump CABG.ConclusionsCompared with off-pump CABG, on-pump CABG is associated with an earlier onset of postoperative stroke during the recovery phase, suggesting different mechanisms in the pathogenesis of stroke between the two surgical approaches

    Towards integration of environmental and health impact assessments for wild capture fishing and farmed fish with particular reference to public health and occupational health dimensions

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    The paper offers a review and commentary, with particular reference to the production of fish from wild capture fisheries and aquaculture, on neglected aspects of health impact assessments which are viewed by a range of international and national health bodies and development agencies as valuable and necessary project tools. Assessments sometimes include environmental health impact assessments but rarely include specific occupational health and safety impact assessments especially integrated into a wider public health assessment. This is in contrast to the extensive application of environmental impact assessments to fishing and the comparatively large body of research now generated on the public health effects of eating fish. The value of expanding and applying the broader assessments would be considerable because in 2004 the United Nations Food and Agriculture Organization reports there were 41,408,000 people in the total ‘fishing’ sector including 11,289,000 in aquaculture. The paper explores some of the complex interactions that occur with regard to fishing activities and proposes the wider adoption of health impact assessment tools in these neglected sectors through an integrated public health impact assessment tool

    Radiation therapy generates platelet-activating factor agonists

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    Pro-oxidative stressors can suppress host immunity due to their ability to generate oxidized lipid agonists of the platelet-activating factor-receptor (PAF-R). As radiation therapy also induces reactive oxygen species, the present studies were designed to define whether ionizing radiation could generate PAF-R agonists and if these lipids could subvert host immunity. We demonstrate that radiation exposure of multiple tumor cell lines in-vitro, tumors in-vivo, and human subjects undergoing radiation therapy for skin tumors all generate PAF-R agonists. Structural characterization of radiation-induced PAF-R agonistic activity revealed PAF and multiple oxidized glycerophosphocholines that are produced non-enzymatically. In a murine melanoma tumor model, irradiation of one tumor augmented the growth of the other (non-treated) tumor in a PAF-R-dependent process blocked by a cyclooxygenase-2 inhibitor. These results indicate a novel pathway by which PAF-R agonists produced as a byproduct of radiation therapy could result in tumor treatment failure, and offer important insights into potential therapeutic strategies that could improve the overall antitumor effectiveness of radiation therapy regimens

    Coordinated modulation of multiple processes through phase variation of a c-di-GMP phosphodiesterase in Clostridioides difficile

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    The opportunistic nosocomial pathogen Clostridioides difficile exhibits phenotypic heterogeneity through phase variation, a stochastic, reversible process that modulates expression. In C. difficile, multiple sequences in the genome undergo inversion through site-specific recombination. Two such loci lie upstream of pdcB and pdcC, which encode phosphodiesterases (PDEs) that degrade the signaling molecule c-di-GMP. Numerous phenotypes are influenced by c-di-GMP in C. difficile including cell and colony morphology, motility, colonization, and virulence. In this study, we aimed to assess whether PdcB phase varies, identify the mechanism of regulation, and determine the effects on intracellular c-di-GMP levels and regulated phenotypes. We found that expression of pdcB is heterogeneous and the orientation of the invertible sequence, or ‘pdcB switch’, determines expression. The pdcB switch contains a promoter that when properly oriented promotes pdcB expression. Expression is augmented by an additional promoter upstream of the pdcB switch. Mutation of nucleotides at the site of recombination resulted in phase-locked strains with significant differences in pdcB expression. Characterization of these mutants showed that the pdcB locked-ON mutant has reduced intracellular c-di-GMP compared to the locked-OFF mutant, consistent with increased and decreased PdcB activity, respectively. These alterations in c-di-GMP had concomitant effects on multiple known c-di-GMP regulated processes, indicating that phase variation of PdcB allows C. difficile to coordinately diversify multiple phenotypes in the population to enhance survival
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