Tailor-made directional emission in nanoimprinted plasmonic-based light-emitting devices

We demonstrate an enhanced and tailor-made directional emission of light-emitting devices using nanoimprinted hexagonal arrays of aluminum nanoparticles. Fourier microscopy reveals that the luminescence of the device is not only determined by the material properties of the organic dye molecules but is also strongly influenced by the coherent scattering resulting from periodically arranged metal nanoparticles. Emitters can couple to lattice-induced hybrid plasmonic–photonic modes sustained by plasmonic arrays. Such modes enhance the spatial coherence of an emitting layer, allowing the efficient beaming of the emission along narrow angular and spectral ranges. We show that tailoring the separation of the nanoparticles in the array yields an accurate angular distribution of the emission. This combination of large-area metal nanostructures fabricated by nanoimprint lithography and light-emitting devices is beneficial for the design and optimization of solid-state lighting systems

Proliferative verrucous leukoplakia : a proposal for diagnostic criteria

Proliferative verrucous leukoplakia (PVL) is a rare form of oral leukoplakia, which was first described in 1985 by Hansen et al. Since then, various published case series have presented PVL as a disease with aggressive biological behaviour due to its high probability of recurrence and a high rate of malignant transformation, usually higher than 70%. PVL is a long-term progressive condition, which is observed more frequently in women and elderly patients over 60 years at the time of diagnosis. Eventually, PVL tends to become multifocal with a progressive deterioration of the lesions, making it more and more difficult to control. Tobacco use does not seem to have a significant influence on the appearance or progression of PVL. These lesions may occur both in smokers and nonsmokers. Nevertheless, at present, the aetiology of PVL remains unclear as well as its management and diagnosis, which is still retrospective, late and poorly defined, lacking consensus criteria. Therefore, the aim of this study is to propose a set of diagnostic criteria to allow for the early and objective identification of PVL cases, and thereby conduct an adequate management. The proposal includes five major criteria and four minor criteria, as well as specific combinations among them in order to establish a correct and objective diagnosis of proliferative verrucous leukoplakia

Co-creation Processes Contributing to the Societal Impact of Science: Contributions from the Net4Impact Network

La participación ciudadana a lo largo del desarrollo de los proyectos de investigación ha demostrado aumentar el impacto social de la ciencia. Los procesos de cocreación promueven un impacto social más significativo al alinear la investigación con las necesidades sociales. En los últimos años se han identificado importantes avances en materia de participación ciudadana en la ciencia. Sin embargo, todavía existen importantes retos que limitan la interacción de la ciudadanía con las creaciones científicas. Este artículo recoge algunas de las aportaciones de la red Net4Impact frente a estos retos. Concretamente, analizamos los procesos de cocreación desarrollados por proyectos que han demostrado impacto social. Este estudio cualitativo se basa en el análisis de Webinars, reuniones con investigadores de diferentes áreas científicas y en el Análisis de Contenido Comunicativo. Como resultado, este trabajo ofrece seis ejemplos de impacto social en tres áreas científicas: ciencias sociales, humanidades e ingeniería. Además, se analizan las características e implicaciones de los distintos procesos de cocreación desarrollados por estos proyectos exitosos

Cosmological gas accretion history onto the stellar discs of Milky Way-like galaxies in the Auriga simulations -- (I) Temporal dependency

We use the 30 simulations of the Auriga Project to estimate the temporal dependency of the inflow, outflow and net accretion rates onto the discs of Milky Way-like galaxies. The net accretion rates are found to be similar for all galaxies at early times, increasing rapidly up to $\sim 10~\mathrm{M}_\odot \, \mathrm{yr}^{-1}$. After $\sim 6~\mathrm{Gyr}$ of evolution, however, the net accretion rates are diverse: in most galaxies, these exhibit an exponential-like decay, but some systems instead present increasing or approximately constant levels up to the present time. An exponential fit to the net accretion rates averaged over the MW analogues yields typical decay time-scale of $7.2~\mathrm{Gyr}$. The analysis of the time-evolution of the inflow and outflow rates, and their relation to the star formation rate (SFR) in the discs, confirms the close connection between these quantities. First, the inflow$/$outflow ratio stays approximately constant, with typical values of $\dot{M}_\mathrm{out}/ \dot{M}_\mathrm{in} \sim 0.75$, indicating that the gas mass involved in outflows is of the order of 25% lower compared to that involved in inflows. A similar behaviour is found for the SFR$/$inflow rate ratio, with typical values between 0.1 and 0.3, and for the outflow rate$/$SFR which varies in the range $3.5$--$5.5$. Our results show that continuous inflow is key to the SFR levels in disc galaxies, and that the star formation activity and the subsequent feedback in the discs is able to produce mass-loaded galaxy winds in the disc-halo interface.Comment: 21 pages, 15 figure

Cosmological gas accretion history on to the stellar discs of Milky Way-like galaxies in the Auriga simulations – II. The inside–out growth of discs

We investigate the growth of stellar discs in Milky Way-mass galaxies using the magnetohydrodynamical simulations of the Auriga Project in a full cosmological context. We focus on the gas accretion process along the discs, calculating the net, infall and outflow rates as a function of galactocentric distance, and investigate the relation between them and the star formation activity. The stellar distributions of around 70 per cent of the simulated galaxies exhibit an ‘inside–out’ pattern, with older (younger) stellar populations preferentially located in the inner (outer) disc regions. In all cases, we find a very tight correlation between the infall, outflow, and net accretion rates, as well as between these three quantities and the star formation rate. This is because the amount of gas which is ultimately available for star formation in each radial ring depends not only on the infall rates, but also on the amount of gas leaving the disc in outflows, which directly relates to the local star formation level. Therefore, any of these rates can be used to identify galaxies with inside–out growth. For these galaxies, the correlation between the dominant times of accretion/star formation and disc radius is well fitted by a linear function. We also find that, when averaged over galaxies with formation histories similar to the Milky Way, the simulated accretion rates show a similar evolution (both temporally and radially integrated) to the usual accretion prescriptions used in chemical evolution models, although some major differences arise at early times and in the inner disc regions

Grapevine virus L: a novel vitivirus in grapevine

Vitiviruses are ssRNA(+) viruses in the family Betaflexiviridae (subfamily Trivirinae). There are currently 10 ICTV recognized virus species in the genus; nevertheless, the extended use of NGS technologies is rapidly expanding their diversity and official recognition of six more have been proposed recently. Here, we present the characterization of a novel virus from grapevine, which fits the genomic architecture and evolutionary constraints to be classified within the Vitivirus genus. The detected virus sequence is 7607 nt long, including a typical genome organization of ORFs encoding a replicase (RP), a 22 kDa protein, a movement protein, a coat protein (CP) and a nucleic acid binding protein. Phylogenetic analyses based on the predicted RP and CP proteins unequivocally place the new virus within the Vitivirus genus. Multiple independent RNAseq data confirmed the presence of the detected virus in berries at diverse developmental stages. Additionally, we detected, confirmed, and assembled virus sequences from grapevine samples of distinct cultivars from America, Europe, Asia and Oceania, sharing 74.4%–97.8% nt identity, suggesting that the identified virus is widely distributed and diverse. We propose the name grapevine virus L (GVL) to the detected Vitivirus.Fil: Debat, Humberto Julio. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigaciones Agropecuarias. Instituto de Patología Vegetal; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Zavallo, Diego. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Agrobiotecnología y Biología Molecular. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Agrobiotecnología y Biología Molecular; ArgentinaFil: Soltero Brisbane, Reid. Foundation Plant Services; Estados UnidosFil: Voncina, Darko. University of Zagreb; CroaciaFil: Almeida, Rodrigo P.. University of California at Berkeley; Estados UnidosFil: Blouin, Arnaud G.. No especifíca;Fil: Al Rwahnih, Maher. University of California at Berkeley; Estados UnidosFil: Gómez Talquenca, Sebastián. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Mendoza-San Juan. Estación Experimental Agropecuaria Mendoza; ArgentinaFil: Asurmendi, Sebastian. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Agrobiotecnología y Biología Molecular. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Agrobiotecnología y Biología Molecular; Argentin

Impacto del daño ocasionado por el picudo negro de la vaina, Rhyssomatus subtilis Fiedler (Coleoptera: Curculionidae), en diferentes etapas fenológicas del cultivo de soja

El picudo negro de la soja, Rhyssomatus subtilis Fiedler, es una plaga ampliamente difundida en gran parte del Noroeste Argentino y la soja constituye uno de sus cultivos hospederos preferidos (Cazado et al., 2013). El picudo afecta al cultivo durante todo su ciclo. En la etapa vegetativa, los adultos se alimentan de los cotiledones, tallos y brotes tiernos de las plantas, llegando a comprometer su estructura e incluso ocasionando su muerte. En la etapa reproductiva, tanto el adulto como la larva causan perjuicios al cultivo. Durante la formación de los granos, las hembras colocan los huevos en el interior de las vainas de soja. Las larvas, al nacer, se alimentan de los granos verdes, llegando a consumir uno o más granos dentro de una misma vaina. La alimentación de las larvas incide en forma directa sobre el rinde del cultivo (Socías et al., 2009). Además, los orificios de alimentación y oviposición constituyen vías de ingreso para patógenos que afectan la calidad de la semilla (Escobar et al., 2009).Fil: Cazado, Lucas Emiliano. Gobierno de Tucumán. Ministerio de Desarrollo Productivo. Estación Experimental Agroindustrial Obispo Colombres; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Casmuz, Augusto Sebastián. Gobierno de Tucumán. Ministerio de Desarrollo Productivo. Estación Experimental Agroindustrial Obispo Colombres; ArgentinaFil: Scalora, Franco S.. Gobierno de Tucumán. Ministerio de Desarrollo Productivo. Estación Experimental Agroindustrial Obispo Colombres; ArgentinaFil: Aralde, Marcos R.. Gobierno de Tucumán. Ministerio de Desarrollo Productivo. Estación Experimental Agroindustrial Obispo Colombres; ArgentinaFil: Aybar Guchea, Matías. Gobierno de Tucumán. Ministerio de Desarrollo Productivo. Estación Experimental Agroindustrial Obispo Colombres; ArgentinaFil: Colledani Toranzo, G. Alejandro. Gobierno de Tucumán. Ministerio de Desarrollo Productivo. Estación Experimental Agroindustrial Obispo Colombres; ArgentinaFil: Gómez, Mario. Gobierno de Tucumán. Ministerio de Desarrollo Productivo. Estación Experimental Agroindustrial Obispo Colombres; ArgentinaFil: Fadda, Lucas A.. Gobierno de Tucumán. Ministerio de Desarrollo Productivo. Estación Experimental Agroindustrial Obispo Colombres; ArgentinaFil: Fernández, José L.. Gobierno de Tucumán. Ministerio de Desarrollo Productivo. Estación Experimental Agroindustrial Obispo Colombres; ArgentinaFil: Gómez, César Horacio. Gobierno de Tucumán. Ministerio de Desarrollo Productivo. Estación Experimental Agroindustrial Obispo Colombres; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Gastaminza, Gerardo Alfredo. Gobierno de Tucumán. Ministerio de Desarrollo Productivo. Estación Experimental Agroindustrial Obispo Colombres; ArgentinaFil: Willink, Eduardo. Gobierno de Tucumán. Ministerio de Desarrollo Productivo. Estación Experimental Agroindustrial Obispo Colombres; Argentin

Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosol

A novel lyase activity enzyme is characterized for the first time: HMG-CoA lyase-like1 (er-cHL), which is a close homolog of mitochondrial HMG-CoA lyase (mHL). Initial data show that there are nine mature transcripts for the novel gene HMGCLL1, although none of them has all its exons. The most abundant transcript is called "variant b," and it lacks exons 2 and 3. Moreover, a three-dimensional model of the novel enzyme is proposed. Colocalization studies show a dual location of the er-cHL in the endoplasmic reticulum (ER) and cytosol, but not in mitochondria or peroxisomes. Furthermore, the dissociation experiment suggests that it is a nonendoplasmic reticulum integral membrane protein. The kinetic parameters of er-cHL indicate that it has a lower Vmax and a higher substrate affinity than mHL. Protein expression and lyase activity were found in several tissues, and were particularly strong in lung and kidney. The occurrence of er-cHL in brain is surprising, as mHL has not been found there. Although mHL activity is clearly associated with energy metabolism, the results suggest that er-cHL is more closely related to another metabolic function, mostly at the pulmonary and brain level.Fil: Arnedo, María. Universidad de Zaragoza; EspañaFil: Menao, Sebastián. Universidad de Zaragoza; EspañaFil: Puisac, Beatriz. Universidad de Zaragoza; EspañaFil: Teresa Rodrigo, María E.. Universidad de Zaragoza; EspañaFil: Gil Rodríguez, María C.. Universidad de Zaragoza; EspañaFil: López Viñas, Eduardo. CENTRO DE BIOLOGIA MOLECULAR SEVERO OCHOA (CBMSO) ; UNIVERSIDAD AUTONOMA DE MADRID; . Universidad Autónoma de Madrid; EspañaFil: Gómez Puertas, Paulino. CENTRO DE BIOLOGIA MOLECULAR SEVERO OCHOA (CBMSO) ; UNIVERSIDAD AUTONOMA DE MADRID; . Universidad Autónoma de Madrid; EspañaFil: Casals, Nuria. Universitat Internacional de Catalunya; EspañaFil: Casale, Cesar Horacio. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Instituto de Biotecnología Ambiental y Salud - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Biotecnología Ambiental y Salud; ArgentinaFil: Hegardt, Fausto G.. Universidad de Barcelona; EspañaFil: Pié, Juan. Universidad de Zaragoza; Españ

Implementación de middleware publicador/subscriptor para aplicaciones web de monitoreo

En la actualidad, millones de clientes se conectan a la nube utilizando el protocolo HTTP (Protocolo de Transferencia de Hipertexto). Históricamente, el estudio de los sistemas distribuidos ha propuesto diversas técnicas de optimización de acceso; como ser Sun RPC, CORBA, SOAP. Sin embargo, en el ámbito de las aplicaciones web una tendencia muy generalizada es la abstención a este tipo de middlewares, en favor de principios arquitectónicos propuestos como REST (Representational State Transfer). Uno de los problemas que presenta esta mecánica de comunicación, es la imposibilidad que un cliente reciba actualizaciones de un recurso remoto sin iniciar un requerimiento. Una técnica actual para mitigar el problema consiste en la utilización de WebSockets. Paralelamente, las bases de datos relacionales han ganado capacidades de notificación a través de canales asincrónicos. Estas pueden ser aprovechadas para recuperar cambios en los datos de tiempo real. En este trabajo se presenta el desarrollo de una aplicación web con requerimientos de actualizaciones de estado en tiempo real. Inicialmente se plantea su diseño exponiendo recursos bajo REST, para luego abordar un enfoque Publicador Subscriptor sobre los mismos recursos utilizando middleware basado en WebSockets.Eje: Arquitectura, Redes y Sistemas Operativos.Red de Universidades con Carreras en Informática (RedUNCI

Multidisciplinary approach detects speciation within the kissing bug Panstrongylus rufotuberculatus populations (Hemiptera, Heteroptera, Reduviidae)

BACKGROUND Panstrongylus rufotuberculatus (Hemiptera-Reduviidae) is a triatomine species with a wide geographic distribution and a broad phenotypic variability. In some countries, this species is found infesting and colonising domiciliary ecotopes representing an epidemiological risk factor as a vector of Trypanosoma cruzi, etiological agent of Chagas disease. In spite of this, little is known about P. rufotuberculatus genetic diversity. METHODS Cytogenetic studies and DNA sequence analyses of one nuclear (ITS-2) and two mitochondrial DNA sequences (cyt b and coI) were carried out in P. rufotuberculatus individuals collected in Bolivia, Colombia, Ecuador and Mexico. Moreover, a geometric morphometrics study was applied to Bolivian, Colombian, Ecuadorian and French Guiana samples. OBJECTIVES To explore the genetic and phenetic diversity of P. rufotuberculatus from different countries, combining chromosomal studies, DNA sequence analyses and geometric morphometric comparisons. FINDINGS We found two chromosomal groups differentiated by the number of X chromosomes and the chromosomal position of the ribosomal DNA clusters. In concordance, two main morphometric profiles were detected, clearly separating the Bolivian sample from the other ones. Phylogenetic DNA analyses showed that both chromosomal groups were closely related to each other and clearly separated from the remaining Panstrongylus species. High nucleotide divergence of cyt b and coI fragments were observed among P. rufotuberculatus samples from Bolivia, Colombia, Ecuador and Mexico (Kimura 2-parameter distances higher than 9%). MAIN CONCLUSIONS Chromosomal and molecular analyses supported that the two chromosomal groups could represent different closely related species. We propose that Bolivian individuals constitute a new Panstrongylus species, being necessary a detailed morphological study for its formal description. The clear morphometric discrimination based on the wing venation pattern suggests such morphological description might be conclusive.MEC-DICYT: II/FVF/2019/054CSIC: No. 16